Yersinia pestis A1122: A1122_07255
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Entry
A1122_07255 CDS
T01831
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ypt
Yersinia pestis A1122
Pathway
ypt00270
Cysteine and methionine metabolism
ypt00450
Selenocompound metabolism
ypt00670
One carbon pool by folate
ypt01100
Metabolic pathways
ypt01110
Biosynthesis of secondary metabolites
ypt01230
Biosynthesis of amino acids
ypt04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
ypt00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
A1122_07255 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
A1122_07255 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
A1122_07255 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
A1122_07255 (metH)
04980 Cobalamin transport and metabolism
A1122_07255 (metH)
Enzymes [BR:
ypt01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
A1122_07255 (metH)
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AEL72106
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Position
1594795..1598490
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AA seq
1231 aa
AA seq
DB search
MVDTVIDNKVKELHQQLAQRILVLDGGMGTMIQSYRLEEADYRGARFADWASDLKGNNDL
LVLSKPEVITAIHNAYLEAGADILETNTFNSTSIAMADYQMASLSAEINYEAARLARICA
DEWSARTPEKPRYVAGVLGPTNRTASISPKVNDPAFRNVSFDQLVEAYRESTRALIEGGV
DLIMIETVFDTLNAKAATFAVESEFEVMGVLLPVMISGTITDASGRTLSGQTTEAFYNSL
RHVKPLSFGLNCALGPDELRQYVAELSRISEYYVSAHPNAGLPNAFGEYDLEAKEMAEQI
GEWARAGFLNIVGGCCGTTPRHIAAMVNAVAGVPPRPLPDIPVACRLAGLEPLTIDANTL
FVNVGERTNVTGSARFKRLIKEEKYGEALDVARQQVESGAQIIDINMDEGMLDAEAAMVR
FLNLIAGEPDIARVPIMIDSSRWDVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLVRR
YGAAMVVMAFDETGQADTRARKIEICRRAYKILTETVGFPPEDIIFDPNIFAVATGIEEH
NNYAVDFIEACADIKAELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMG
IVNAGQLAIYDDLSDELRDAVEDVILNRRDDSTERLLDLAEKYRDSKSGEVAIQQAEWRG
WPVVKRLEYSLVKGITEFIELDTEEARQQADRPIEVIEGPLMSGMNVVGDLFGEGKMFLP
QVVKSARVMKQAVAYLEPYIEASKQKGTTAGKILLATVKGDVHDIGKNIVGVVLQCNNYE
IIDLGVMVPTEKILRTAREEKVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGAT
TSKAHTAVKIEQNYSGSTTYVSNASRSVGVVSALLSDTQREAFVAKTRKEYETVRIQHAR
KKPRTPPVSLQAARNNPTVIDWENYTPPVAHKLGVQVVEASIETLRNYIDWTPFFMTWSL
AGKYPRILEDEVVGEEAKRLLADANALLDKLSAEDLLHPKGVVGLFPANSVGDDIEIYRD
ERRDEVLAISYHLRQQTEKTDFPNYCLADYVAPKSSGKADYFGAFAVTGGLEEDALADAY
DAQHDDYNKIMIKALSDRLAEAFAEYLHERVRKVYWGFAPNENLSNEELVRENYQGIRPA
PGYPACPEHTEKGQIWQLLDVETHTGMKLTESYAMWPGASVSGWYFSHPDSKYFAVAQIQ
RDQVEDYAARKGMPTAEVERWLAPNLGYDAD
NT seq
3696 nt
NT seq
+upstream
nt +downstream
nt
gtggtggatacagtaatcgataataaggtcaaggaattgcaccagcagttggcgcaacgc
attttggtactggatggtggtatgggcaccatgatccagagctaccgattagaagaagca
gattaccgaggcgcgcgttttgctgactgggcaagtgacctaaaaggtaacaatgacctc
ttggtgctctccaagccagaagtcatcacggcgatccataatgcctaccttgaagccggt
gctgacattctcgaaaccaatacctttaactctacctccattgcgatggcggactatcag
atggcgtcactgtcggctgaaattaactatgaagccgcccgtctggcccgtatctgtgcc
gatgaatggagcgcccgcacgccagaaaaaccacgttatgttgccggggtgctggggcca
accaaccgtactgcctccatctcccctaaagttaatgacccggcgttccgtaacgtcagt
tttgatcagttggtcgaggcctatcgtgagtctacccgcgcgctgattgaagggggtgtt
gatttaattatgatcgaaacggtcttcgatacgttgaatgcgaaggccgcgacctttgcg
gttgaaagcgaattcgaagtgatgggcgtgctgttgccggtgatgatttccggcaccatt
accgatgcctccggccgtacgctgtctggtcaaacgacggaagctttttataactcgctg
cgccatgtcaaaccgctgtcgtttggtctgaactgtgcgctggggccggatgaactgcgc
caatatgttgctgagttatcgcgtatctctgaatattatgtcagtgcgcacccgaatgcc
ggtttgccgaatgcttttggtgaatatgatctggaagccaaagagatggctgagcagatt
ggcgagtgggcacgtgccggatttttgaatattgtcggcggttgctgcggtaccacaccc
cggcatattgcggcgatggtcaacgctgtcgctggggtgcctccgcgcccgttgcctgat
attccggttgcctgccgtttggccgggctggagccactgactatcgatgccaataccctg
tttgtgaacgtcggtgagcggaccaacgtcacgggttcggcacgctttaaacggctgata
aaagaagagaagtacggagaggcgctggatgttgcccgccaacaggtcgaaagcggcgcg
cagatcatcgatatcaacatggacgaaggcatgttggatgccgaagcggccatggtgcgt
ttccttaatctgattgccggggagcctgatattgccagggtgccgattatgatcgactcc
tcaaggtgggatgtgattgaaaaaggcctgaaatgtattcaaggcaaaggcatcgtgaac
tccatttcgatgaaagagggcgttgatgcctttattcatcacgccaaactggtacgccgt
tatggtgccgccatggtggtcatggcctttgatgaaaccgggcaagccgatacccgcgca
cgcaaaatcgagatttgccgccgtgcgtataaaatattgacggaaaccgtcggtttccca
ccagaagatattatcttcgatccgaatatttttgccgtagcgacggggattgaagagcat
aacaattatgccgtcgattttattgaagcctgtgccgatatcaaagccgagttgcctcac
gcgctgatttctggcggtgtctccaacgtttccttctctttccgagggaatgatccagta
cgtgaagccattcatgcagtgttcctctattacgctattcgcaatggcatggatatgggg
attgttaacgccggtcaattggcgatttatgacgacctgtctgatgaattacgtgatgcg
gtcgaggatgtgatcctcaaccgccgtgatgacagtactgagcgcctgctggatttagca
gaaaaataccgtgacagtaaaagtggcgaggtcgcgatccagcaagcagaatggcgtggt
tggccggtggtgaaacggttagagtattcgctggtaaaaggcattactgaatttattgag
ctggataccgaagaagcgcgccagcaggcagatcggccaattgaagtgattgaagggccg
ttaatgtctgggatgaatgtggttggtgacttgtttggtgaaggaaaaatgttcctgcca
caggttgtaaaatcagccagggtaatgaaacaggcggtggcctatctcgaaccttatatt
gaagccagtaagcagaagggtaccaccgccggtaaaatcttattagcaaccgtcaaaggc
gatgtgcatgacatcggcaagaacatcgtgggtgtggttttgcagtgtaataactatgaa
atcatcgatctgggcgtgatggtgccgacggaaaaaattctgcgcactgcacgggaagag
aaggtggatattatcggcctgtctggtctgattaccccgtcgctggacgagatggttaac
gtggcgaaagagatggagcgccaaggctttacgctgccgttgctcattggtggcgcaacg
acatccaaagctcacaccgcggtcaagattgaacaaaattatagcggttccaccacgtat
gtctctaacgcctcgcgcagtgtgggcgtggtatccgcgttgctatcggatacgcaacgg
gaggcatttgtggcaaaaacccgcaaagaatatgagactgtacgtatccaacacgcccgt
aaaaaaccgcgcaccccgccggtcagtttgcaggctgcacggaataacccaacggtgatt
gattgggagaactacactccgccagtggcccataaattgggggtacaggtggtggaggcc
agtattgaaactctgcgcaactatatcgactggacgccattctttatgacctggtcgttg
gcaggcaagtatccgcgcattttagaagatgaggtggtgggggaggaggccaagcgcctg
ctcgccgacgccaatgctttgttggataaattgtccgccgaggatctgctgcatccaaaa
ggcgtggttggtctgttcccggctaacagcgtcggcgatgatatcgaaatttaccgtgat
gagcggcgagatgaggtactggccatcagctatcatttacgccaacagaccgaaaaaacc
gacttcccgaactactgtttagctgactatgtcgcgcctaaatccagtggtaaagccgat
tattttggtgcgtttgcggtgaccggtggcttggaagaagacgcattggccgatgcttat
gatgcgcaacatgatgactacaataaaatcatgattaaggcattatcagaccgtctggcc
gaagcctttgccgagtatctgcatgagcgagtacgtaaagtgtattggggttttgcaccg
aacgaaaatctgagcaacgaagagttggtgcgcgaaaattatcaggggatccgcccggca
ccgggctatcccgcttgcccggagcacaccgagaaaggccaaatttggcagttgttggat
gtcgaaacccacaccggtatgaaactgaccgaatcctacgccatgtggcctggggcttcg
gtatcgggttggtatttcagccacccagacagcaaatattttgccgtagcacaaattcag
cgtgatcaggttgaggattatgccgcccgtaaagggatgcccactgccgaagttgaacgc
tggctagcccctaatctgggttacgatgcggattga
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