Zalophus californianus (California sea lion): 113910123
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Entry
113910123 CDS
T07874
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca01522
Endocrine resistance
zca04012
ErbB signaling pathway
zca04062
Chemokine signaling pathway
zca04148
Efferocytosis
zca04151
PI3K-Akt signaling pathway
zca04360
Axon guidance
zca04370
VEGF signaling pathway
zca04510
Focal adhesion
zca04517
IgSF CAM signaling
zca04518
Integrin signaling
zca04670
Leukocyte transendothelial migration
zca04810
Regulation of actin cytoskeleton
zca04935
Growth hormone synthesis, secretion and action
zca05100
Bacterial invasion of epithelial cells
zca05135
Yersinia infection
zca05146
Amoebiasis
zca05163
Human cytomegalovirus infection
zca05165
Human papillomavirus infection
zca05170
Human immunodeficiency virus 1 infection
zca05200
Pathways in cancer
zca05202
Transcriptional misregulation in cancer
zca05205
Proteoglycans in cancer
zca05208
Chemical carcinogenesis - reactive oxygen species
zca05222
Small cell lung cancer
zca05417
Lipid and atherosclerosis
zca05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
113910123 (PTK2)
04370 VEGF signaling pathway
113910123 (PTK2)
04151 PI3K-Akt signaling pathway
113910123 (PTK2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
113910123 (PTK2)
04518 Integrin signaling
113910123 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
113910123 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
113910123 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
113910123 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
113910123 (PTK2)
04062 Chemokine signaling pathway
113910123 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
113910123 (PTK2)
09158 Development and regeneration
04360 Axon guidance
113910123 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113910123 (PTK2)
05202 Transcriptional misregulation in cancer
113910123 (PTK2)
05205 Proteoglycans in cancer
113910123 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
113910123 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
113910123 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
113910123 (PTK2)
05163 Human cytomegalovirus infection
113910123 (PTK2)
05165 Human papillomavirus infection
113910123 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
113910123 (PTK2)
05100 Bacterial invasion of epithelial cells
113910123 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
113910123 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113910123 (PTK2)
05418 Fluid shear stress and atherosclerosis
113910123 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
113910123 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113910123 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
zca01009
]
113910123 (PTK2)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
113910123 (PTK2)
Protein kinases [BR:
zca01001
]
Non-receptor tyrosine kinases
FAK family
113910123 (PTK2)
Protein phosphatases and associated proteins [BR:
zca01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
113910123 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
113910123
NCBI-ProteinID:
XP_027427768
UniProt:
A0A6J2BD91
LinkDB
All DBs
Position
4:complement(188265076..188520341)
Genome browser
AA seq
1140 aa
AA seq
DB search
MLLELAGQGALRPAGAVCMEKSGCSPFPMCWAKEYDRYIASSKIMAAAYLDPNLNHTPNS
STKPHLGTGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGMRTHAVSVSGVSPCQHKVKKARRFLPLVFCSHEPSPTDEISGDETDDYAEIID
EEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMES
RRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSAYPGSHGITA
MAGSIYPGQASLLDQTDSWNPRPQEISMWQPNVEDSAALDLRGIGQVLPTHLMEERLIRQ
QQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPTGNQHIYQPVGKPDPAAPPKK
PPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPPTANLDRSNDRVYENVTGLV
KAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLPVLPASTHREIEMAQKLLNS
DLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLRMLGPTRPH
NT seq
3423 nt
NT seq
+upstream
nt +downstream
nt
atgttgctggaactggcgggccaaggggccctgagaccagcaggtgccgtctgtatggag
aagagcggctgtagtccatttccaatgtgttgggctaaagagtatgacagatacatagca
tctagcaaaataatggcagctgcttaccttgacccaaacttgaatcacacaccgaattcg
agtaccaagcctcacctgggtactggagtggaacgttcccctggggcaatggagcgagtg
ttgaaggtctttcattattttgaaaacagcagtgagccagccacttgggccagtattatc
aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgcctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaggacaagccaactctgaatttcttctatcaacaggtgaagagcgactacatg
tctgagatagctgaccgcgtggaccaggacattgctttgaagctgggctgtctagagata
cggcgctcgtactgggagatgcgaggcaacgcgctagagaagaagtccaactatgaagtg
ctggaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacactaagaaagctgatccaacagacatttagacagtttgccaatcttaacaga
gaagaaagtattctgaagttctttgagatcctctccccagtgtacagatttgataaagaa
tgcttcaagtgtgctctgggttcaagctggattatttcggtagaactggcaattggccca
gaagaaggaatcagttacctcacggacaaggggtgcaaccccacacatctggccgacttc
aatcaagtgcagaccattcagtattcaaacagcgaagacaaggacaggaaagggatgcta
cagctgaaaattgccggcgccccagagcctctgacagtgacagcaccatccctgaccatc
gctgagaatatggctgacttgatagatgggtactgccggctggtgaacggggccacacag
tcttttatcatcagaccccagaaagaaggtgaacgggctttgccatcaataccaaagctg
gccaacagcgagaagcaaggcatgcggacacacgcggtctccgtatcaggagtcagtccc
tgccaacataaagttaagaaagctaggcgctttctccctttggtcttctgttcccatgag
ccttctcctacggatgaaattagtggggacgaaacagatgattatgctgagattatagac
gaagaagatacctacaccatgccctcaaaaagctatggaatagatgaagccagggattat
gagattcagagagaaagaatcgagcttggacggtgcattggggaaggccagtttggagac
gtccatcaaggcgtctatatgagcccagagaatccagctttggcggttgcaattaaaaca
tgtaaaaactgtacttcggacagcgtgagagagaaattccttcaagaagccttaacgatg
cgccagtttgaccaccctcacattgtgaaactgattggtgtcatcacggagaaccctgtc
tggataatcatggagctgtgcacgcttggagagctgaggtcatttctgcaagtaaggaag
tacagtttggatctggcgtctttgatcctatatgcctatcagcttagtacagccctcgcg
tatctggagagcaaaagatttgtgcacagggacattgctgctcggaatgttctggtatcc
tcaaatgattgtgtaaaactaggagactttggattatcccgatatatggaagacagtact
tactacaaagcttccaaaggaaaattgccaattaagtggatggctccagagtccatcaat
tttcgacgttttacctcagctagtgatgtatggatgtttggtgtatgtatgtgggagata
ctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcggtcgaatt
gagaatggggagagattaccaatgcctccaaattgccctcctaccctctacagccttatg
acgaaatgctgggcctatgaccccagcaggcggccccggttcactgagctcaaagctcag
ctcagcacaatcctggaggaggagaaggttcagcaagaagaacggatgaggatggagtcc
agaagacaggtcacagtgtcctgggactccggagggtccgacgaagcgccacccaagccc
agcagacccggttacccgagtccaaggtccagtgaaggattttatcccagcccacagcac
atggtacaaaccaatcattaccaggtctctgcctatcctggttcacatgggatcacggcc
atggctggcagcatctacccgggtcaggcatctcttttggaccagacggattcctggaat
cctagaccgcaggagatatcaatgtggcagcccaacgtggaggactctgctgcactggac
ctgcgtgggatcggacaggtgttgccgacccacctgatggaagagcggctgatccggcag
cagcaggagatggaagaagatcagcgctggctagaaaaagaggagagattcctgaaacct
gacgtgcggctctctcgaggcagtatcgacagggaggatggaagtctccagggtccgact
ggaaaccaacacatatatcagcctgtggggaaaccagatcctgcggctccgccaaagaaa
ccgccacggcctggggcccccggtcacctgggcagcctcgccagcctcagcagccccggg
gacagttacaacgagggcgtcaagccatggaggcttcagccccaggaaatcagcccccca
cccactgccaacctggaccggtccaacgacagggtgtacgagaatgtgacgggcctggtg
aaggctgtcatcgagatgtccagcaagatccagcctgccccgccagaggagtacgttccc
atggtgaaggaagtcggcctggccctgcggacgttactggccactgtggacgagaccctc
ccagtcctgccagccagcactcaccgagagattgagatggcccagaagctgttgaactcc
gacctgggtgagctcatcaacaagatgaaactggcccagcagtacgtcatgaccagtctc
cagcaggagtacaaaaagcaaatgctgaccgcggctcacgccctggccgtggacgccaaa
aacttactcgatgtcattgaccaagcgagactgcggatgctcggaccgacgaggccacac
tga
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