Zalophus californianus (California sea lion): 113912429
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Entry
113912429 CDS
T07874
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04014
Ras signaling pathway
zca04072
Phospholipase D signaling pathway
zca04148
Efferocytosis
zca04360
Axon guidance
zca04625
C-type lectin receptor signaling pathway
zca04630
JAK-STAT signaling pathway
zca04650
Natural killer cell mediated cytotoxicity
zca04660
T cell receptor signaling pathway
zca04670
Leukocyte transendothelial migration
zca04722
Neurotrophin signaling pathway
zca04920
Adipocytokine signaling pathway
zca04931
Insulin resistance
zca05168
Herpes simplex virus 1 infection
zca05205
Proteoglycans in cancer
zca05208
Chemical carcinogenesis - reactive oxygen species
zca05211
Renal cell carcinoma
zca05220
Chronic myeloid leukemia
zca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
113912429 (PTPN11)
04630 JAK-STAT signaling pathway
113912429 (PTPN11)
04072 Phospholipase D signaling pathway
113912429 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
113912429 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
113912429 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
113912429 (PTPN11)
04660 T cell receptor signaling pathway
113912429 (PTPN11)
04670 Leukocyte transendothelial migration
113912429 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
113912429 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
113912429 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
113912429 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
113912429 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
113912429 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113912429 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
113912429 (PTPN11)
05211 Renal cell carcinoma
113912429 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
113912429 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
113912429 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
zca01009
]
113912429 (PTPN11)
Enzymes [BR:
zca01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
113912429 (PTPN11)
Protein phosphatases and associated proteins [BR:
zca01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
113912429 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
113912429
NCBI-ProteinID:
XP_027431249
UniProt:
A0A6J2BGZ7
LinkDB
All DBs
Position
14:10096719..10178389
Genome browser
AA seq
658 aa
AA seq
DB search
MKEILLGTREESSEVDGNHGGLRYFPSPADHAPSPTGGAGRIAGSYQEEVKERTVTREKR
GKRKRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT
GDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSG
KEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKY
DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET
TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE
PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE
VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTV
WQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL
IDVIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKS
KRKGHEYTNIKYSLTDQTSGDQSPLPPCTPTPSCAEMREDNARVYENVGLMQQQKSFR
NT seq
1977 nt
NT seq
+upstream
nt +downstream
nt
atgaaggaaatcttgttgggaactagagaggaatcctctgaagtggatggcaatcatggt
ggacttcgttatttccccagtcccgctgaccatgcccccagccccaccggcggtgctggc
aggatcgcaggctcctaccaagaggaagtcaaggagaggacagtgacccgggagaagagg
gggaagaggaagagaagatggtttcacccaaacatcactggcgtggaggcagaaaacctg
ctgttgacgcgaggagttgatggcagttttttggcgaggcccagtaaaagcaaccctgga
gacttcaccctttccgtcagaagaaatggcgctgtcacccacatcaagattcagaacact
ggtgattactatgacttgtacggaggggagaagtttgccactttggctgagttggtccaa
tattacatggaacatcacgggcaattaaaagagaagaatggagatgttattgagcttaaa
tatcctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctctctggg
aaagaagcagagaaattactaactgagaaaggaaaacacggtagctttctggtacgagag
agccagagccaccccggagattttgttctgtctgtccgaactggtgacgacaaaggggag
agcaatgatggcaagtctaaagtgacccacgtcatgatccgctgtcaggagctgaaatat
gatgttggtggaggagaacggtttgactctttgacagatcttgtggagcattacaagaag
aatcccatggtggaaacattgggcacagtactacaactcaagcagcccctcaacacaaca
cgtatcaatgctgctgaaatagaaagccgggttcgagaactaagcaaattagctgagacc
acagataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgc
aaacttctctacagccgaaaagagggtcagaggcaagaaaataagaacaaaaatagatat
aaaaacatcctgccctttgatcataccagggttgtcctacacgacggtgatcccaatgag
cctgtttcagattacatcaatgcaaatattatcatgcctgagtttgaaaccaaatgcaac
aattcaaagcccaaaaagagttacattgccacacaaggctgcctgcaaaacacggtgaat
gacttttggcggatggtatttcaagagaactcccgagtgattgtcatgacaacgaaagaa
gtggagagaggaaagagtaaatgtgtcaaatactggcctgacgagtatgctctaaaagaa
tatggggtcatgcgtgttaggaacgtcaaagaaagtgctgctcatgactatacattaaga
gaacttaaactttcaaaagttggacaagctctactccaggggaatacagagagaaccgtg
tggcaataccactttcggacctggccggaccacggagtgcccagtgaccctgggggcgtg
ctggacttcctggaggaggtccaccataagcaagagagcattatggatgcagggcctgtg
gtagttcactgcagtgctggaatcggccgtacagggacgttcattgtgattgatatcctc
attgacgtcatcagagagaaaggcgtcgactgtgacatcgatgttcccaaaaccattcag
atggtgcggtctcagaggtcagggatggtccagacagaagcacagtaccgattcatctat
atggccgtccagcattacattgaaacactacaacgcaggattgaagaagagcagaaaagc
aagaggaaagggcatgaatatacaaatattaagtattctctaacggaccagacaagtgga
gatcagagtcccctcccgccttgtacgccaacaccatcttgtgcagaaatgagagaagat
aatgctagagtctatgaaaacgttggtctgatgcagcagcagaaaagcttcagatga
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