Zalophus californianus (California sea lion): 113916517
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Entry
113916517 CDS
T07874
Symbol
INSR
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04010
MAPK signaling pathway
zca04014
Ras signaling pathway
zca04015
Rap1 signaling pathway
zca04022
cGMP-PKG signaling pathway
zca04066
HIF-1 signaling pathway
zca04068
FoxO signaling pathway
zca04072
Phospholipase D signaling pathway
zca04150
mTOR signaling pathway
zca04151
PI3K-Akt signaling pathway
zca04152
AMPK signaling pathway
zca04211
Longevity regulating pathway
zca04213
Longevity regulating pathway - multiple species
zca04520
Adherens junction
zca04910
Insulin signaling pathway
zca04913
Ovarian steroidogenesis
zca04923
Regulation of lipolysis in adipocytes
zca04930
Type II diabetes mellitus
zca04931
Insulin resistance
zca04932
Non-alcoholic fatty liver disease
zca04960
Aldosterone-regulated sodium reabsorption
zca05010
Alzheimer disease
zca05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113916517 (INSR)
04014 Ras signaling pathway
113916517 (INSR)
04015 Rap1 signaling pathway
113916517 (INSR)
04066 HIF-1 signaling pathway
113916517 (INSR)
04068 FoxO signaling pathway
113916517 (INSR)
04072 Phospholipase D signaling pathway
113916517 (INSR)
04022 cGMP-PKG signaling pathway
113916517 (INSR)
04151 PI3K-Akt signaling pathway
113916517 (INSR)
04152 AMPK signaling pathway
113916517 (INSR)
04150 mTOR signaling pathway
113916517 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
113916517 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
113916517 (INSR)
04923 Regulation of lipolysis in adipocytes
113916517 (INSR)
04913 Ovarian steroidogenesis
113916517 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
113916517 (INSR)
09149 Aging
04211 Longevity regulating pathway
113916517 (INSR)
04213 Longevity regulating pathway - multiple species
113916517 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
113916517 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
113916517 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
113916517 (INSR)
04932 Non-alcoholic fatty liver disease
113916517 (INSR)
04931 Insulin resistance
113916517 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113916517 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
zca04090
]
113916517 (INSR)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
113916517 (INSR)
Protein kinases [BR:
zca01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
113916517 (INSR)
CD molecules [BR:
zca04090
]
Proteins
113916517 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
DUF4476
B2
Motif
Other DBs
NCBI-GeneID:
113916517
NCBI-ProteinID:
XP_027438797
EnsemblRapid:
ENSZCAG00025004021
UniProt:
A0A6J2C863
LinkDB
All DBs
Position
1:6295843..6420066
Genome browser
AA seq
1381 aa
AA seq
DB search
MGAGAGRGAASAPLLLAVAALLLGATGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTSCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSQCL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNRCKNSRRQG
CHQYAIHNSKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC
TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQVEDSELYELDYCLKGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRKSSSSPGAENTRPSRKRRALGDVANVTAAAPTVPGF
PNTSTSAPTSPEEHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYVS
ARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVS
RRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGP
LIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPRE
KITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGF
TCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAA
EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVR
WMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNC
PERVTDLMRMCWQFNPKMRPTFLEIVELLKDDLHPSFPEVSFFHSEENKAPESEELEMEF
EDMESVPLDRASHSQREEAGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNP
S
NT seq
4146 nt
NT seq
+upstream
nt +downstream
nt
atgggcgccggggctgggcggggggcggcgtccgcgccgctgctgctggcggtggccgcg
ctgctgctgggtgccacgggccacctgtaccccggagaagtgtgccctggcatggatatc
cggaacaacctcacgaggttgcatgagctggccaactgctcggtcattgaaggacatttg
caaatactgttgatgttcaaaacgaggcccgaggatttccgggacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag
gacctgttccccaacctcacggtcatccggggctcgcgtctgttcttcaactatgcgctg
gtcatcttcgagatggttcacctgaaggagcttggcctctacagcttgatgaacattacc
cggggctccgtccgcattgagaagaacaatgagctctgctacctggccaccattgactgg
tcgcgcatcctggattctgtggaggataattacattgtgctgaacaaagacgacaacgag
gagtgtggggacatttgtccaggcactgcaaagggcaagaccagctgccccgccactgtc
atcaacgggcagtttgtcgagcggtgttggacacacagccactgccagaaagtttgtccc
accatctgcaagtcacacggctgtaccgccgagggtctctgctgccacagccagtgttta
ggcaattgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg
gatggcaggtgcgtggagacctgcccgcccccgtactaccacttccaagactggcgctgc
gtgaacttcagcttctgccaggacctgcacaacagatgcaagaactcccggagacagggc
tgccaccagtatgccattcacaatagcaagtgtatccctgagtgcccctctggctacacg
atgaattccagcaacctgatgtgcactccatgcctgggcccctgtcccaaggtctgccac
atcctggagggcgagaaaaccattgactcggtgacgtctgcccaggagcttcgaggctgc
actgttgtcaacggaagcctcatcatcaacatccgagggggcaacaacctggcagctgag
ctggaggccaacctaggactcattgaagaaatttctgggtatctgaaaatccggagatcc
tacgctcttgtgtcactttcttttttccggaagttacggctgattcgaggagagaccttg
gaaatcgggaactactctttctacgccttggacaaccagaacctaaggcagctctgggac
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactacaatcccaaa
ctctgcttgtcagaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag
aggaacgacattgccctgaagaccaatggggaccaggcgtcttgtgaaaatgaactcctt
aaattttcttacattcggacatcgtatgacaagatcttgctgaaatgggagccgtactgg
ccccctgacttccgagacctcctggggttcatgcttttctacaaagaggccccttaccag
aatgtgaccgagttcgacgggcaggatgcgtgtggttccaacagctggacggtggtggac
atcgacccacctctgcggtccaacgaccccaagtcgcagaaccacccagggtggctgatg
cggggtctcaagccctggacccagtatgccatctttgtcaagaccttggtcaccttttct
gatgaacgccgcacgtatggggccaagagtgatatcatctatgtacagacggatgccact
aacccttccgtccccctggatccaatctccgtttctaactcctcgtcccagattattctg
aagtggaagcctccctctgatcccaatggcaacatcacgcactacctggttttctgggag
aggcaggtggaagacagtgagctgtatgagctggattactgcctcaaagggttgaaactg
ccgtcccggacctggtctccgccgttcgaggccgagggctcccagaagcacaaccagagt
gaatacgaggagtctgccggcgaatgttgctcctgccccaagacggactctcagatcctc
aaggagctggaggagtcctcttttaggaagacctttgaggattacctgcacaatgtggtg
ttcgtccccagaaaatcctcttcaagccctggtgctgagaacactaggccatcgcggaaa
cgccgggccctcggggacgttgccaatgtgacggcagccgcgcccacggttccaggtttc
cccaacacctcgaccagcgcgcccacgagcccggaggagcacaagcccttcgagaaagtg
gtgaacaaagaatccctggtcatctctgggctgcgccacttcactggctaccgcatcgag
ctgcaggcttgcaaccaagactcccccgaggagaggtgcagcgtggccgcctacgtcagc
gccaggaccatgcccgaagccaaggcagatgacattgttggccccgtgacccacgaaatc
ttcgagaacaatgtcgttcacttgatgtggcaggagccaaaggaacccaacggtctgatc
gtgctgtatgaagtgagttaccgacgctatggtgatgaggagctgcacctctgtgtctcc
cgcagacattttgctctggagcggggctgcaggctgcgcgggctgccgccagggaattac
agtgtgcgagtccgggccacctccctggcaggcaacggctcatggacagaagctacctat
ttctacgtgacagactatttagatgtcccgtcgaatattgcaaaaatcatcatcggcccc
ctcatctttgtctttctcttcagtgttgtgattggaagtatttacctgttcctgagaaag
aggcagccggatgggccactgggaccgctgtatgcgtcttcaaaccctgagtacctcagt
gccagtgatgtctttccatgttctgtgtatgtgccggatgagtgggaggtgcctcgggag
aagatcacgctcctgcgtgagctggggcagggctccttcggcatggtgtacgaaggcaac
gccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaagacagtcaacgag
tcggccagtctgcgggagaggatcgagtttctcaacgaggcctcagtcatgaagggcttc
acctgtcatcatgtggtccgcctcctgggggtggtgtccaaaggccagccaacgctggtg
gtgatggagctgatggctcacggtgacctgaagagctacctccgctccctgcggccggag
gctgagaataaccccggccgccctccccctaccctgcaagagatgattcagatggcggca
gagatcgccgatgggatggcctacctgaatgccaagaagtttgtgcaccgggatctcgca
gcccgaaactgcatggtcgcccacgatttcactgtcaaaattggagactttgggatgacc
agagacatctatgaaacggattactaccggaaaggaggcaagggtctgctccccgtgcgg
tggatggcaccggaatccctgaaggacggggtctttaccacttcttctgacatgtggtcc
ttcggcgtggtcctttgggaaatcaccagcttggcagaacagccttaccaaggtctgtct
aatgaacaggtgttgaaatttgtcatggatggagggtatctggatcaacccgacaattgt
ccagagagagtcaccgacctgatgcgtatgtgctggcagttcaatcccaagatgcggccc
accttcctagagatcgtcgaactgctcaaggacgacctgcaccccagctttccagaagtt
tccttcttccacagcgaggagaacaaggcgcctgagagcgaggagctggagatggagttc
gaggacatggagagtgtccccctggatcgggcctcacactctcagagggaggaggccggg
ggccgggatggagggtcctcgctgggcctaaaacggaactacgaggagcacatcccctac
acccacatgaacgggggcaagaaaaacggacggattctgactctgccgaggtcaaatcct
tcctaa
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