Zalophus californianus (California sea lion): 113918596
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Entry
113918596 CDS
T07874
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04062
Chemokine signaling pathway
zca04151
PI3K-Akt signaling pathway
zca04217
Necroptosis
zca04550
Signaling pathways regulating pluripotency of stem cells
zca04630
JAK-STAT signaling pathway
zca04658
Th1 and Th2 cell differentiation
zca04659
Th17 cell differentiation
zca05161
Hepatitis B
zca05162
Measles
zca05166
Human T-cell leukemia virus 1 infection
zca05169
Epstein-Barr virus infection
zca05200
Pathways in cancer
zca05203
Viral carcinogenesis
zca05223
Non-small cell lung cancer
zca05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
113918596 (JAK3)
04151 PI3K-Akt signaling pathway
113918596 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
113918596 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
113918596 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
113918596 (JAK3)
04659 Th17 cell differentiation
113918596 (JAK3)
04062 Chemokine signaling pathway
113918596 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113918596 (JAK3)
05203 Viral carcinogenesis
113918596 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
113918596 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113918596 (JAK3)
05161 Hepatitis B
113918596 (JAK3)
05162 Measles
113918596 (JAK3)
05169 Epstein-Barr virus infection
113918596 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
113918596 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113918596 (JAK3)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
113918596 (JAK3)
Protein kinases [BR:
zca01001
]
Non-receptor tyrosine kinases
JAK family [OT]
113918596 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
Kdo
ABC1
Kinase-like
FERM_C_FAK1
FERM_M
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
113918596
NCBI-ProteinID:
XP_027442969
UniProt:
A0A6J2CFE5
LinkDB
All DBs
Position
1:complement(13423335..13440768)
Genome browser
AA seq
1111 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA
SGILPVYHSLFALATEDLSCWFPPSHVFSVEDSGTQVLVYRLRLLPFPNSFYFPNWFGLE
KCHRFGLRKDLASAILDLPVLEHLFAQHRNDLVSGHLPVGLSLKEQGECLSLAVLDLARM
AHEQAQQPEELLKTVSYKVCLPPDLRDLIQGLSFVTRKRIRRTVRRALRRVTACQADRHS
LMAKYIMDLERLDPARAVETFLVSLPGAAGGLDAQGLLRVAGDTGIAWSPGGQEALQPFC
DFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTS
DSRHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDCFLL
TVCVQTPLGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWDGGLHVDGVALNLTF
CCTPKPKEKSNLIVVRRGCSTPTSSPVQPQSQYQLNQMTFHKIPADSLEWHENLGHGSFT
KIYRGCRHEVVEGEARETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMA
GDSIMVQEFVHLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKV
LLAREGADGNLPFIKLSDPGVSPSVLSREMLTDRIPWVAPECLQEARTLGLEADKWGFGA
TVWEVFSGIPMPISTLDPAKKLQFYEERQQLPAPKWMELAILIQQCMAYEPGQRPSFRAI
IRDLNSLITSDYELLSDPTPGALAPRDGLWNGAQLYAYQDPTIFEERHLKYISQLGKGNF
GSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFRREIQILKALHSDFIVKYRGVSYGP
GRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAAR
NILVESETHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSF
GVVLYELFTYGNKSCSPSAEFLRMMACDGDVPALCCLLELLAEGQRLPAPPACPGEVHEL
MKLCWAPSPQDRPTFSALGPQLDALWSASQG
NT seq
3336 nt
NT seq
+upstream
nt +downstream
nt
atggcacctccaagcgaggagacacccctgattcctcagcgttcctgcagcctctcgtct
tcagaagctggtgccctgcacgtgctgctgccccctcggggccctggacccccacagcgc
ctatctttctcctttggggatcattcagctgaagagctgtgtgtttgggctgctaaggcc
agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggatctgtcctgc
tggttccccccaagccacgtcttctccgtggaggactcgggcacccaagtcctggtctac
aggctccggcttctccccttccccaacagcttttacttccccaactggtttgggctagag
aagtgccaccgctttgggctacgaaaggacttggccagcgccatccttgacctaccagtc
ctggagcacctcttcgcccagcaccggaatgacctggtgagtggccacctccccgtgggc
ctcagtctcaaggagcagggtgaatgtctcagcctggcggtgctggacctggcccggatg
gctcacgagcaggctcagcagcctgaggaactgctgaaaactgtcagctacaaggtctgc
ctgccccccgacctgcgcgacctgatccagggcctgagcttcgtgacgcggaagcgcatc
cgcaggactgtgcgcagggccctgcgccgcgtgaccgcctgccaggctgacaggcactcg
ctcatggccaagtacatcatggacctggagaggctcgacccggccagggcggtcgagacc
ttcctcgtgagcctccccggggctgctggtggtctggatgcgcaggggctgctccgagtg
gctggtgacaccggcattgcctggagtccaggaggacaagaggccctccagcccttctgc
gactttccagaaattgtggacatcagcatcaagcaggctccgcgtgttggcccggccggg
gagcaccgcctggtcaccgtcacgaggacagacaaccagatcctggaggccgagttcccg
gggctgcccgccgcgttgtccttcgtggcgctcgtcgacggctacttcaggctgacctcc
gactccaggcacttcttttgcaaggaggttgcgccgccgcggctgctggaggaggtggcc
gagcagtgccacggccccatcaccctggattttgccatcaacaagctcaagactgggggc
tcacttcccggctcctacgttctccgccgcagtccccaggattttgattgcttcctcctc
actgtctgtgtccagacccccctgggtcctgattataagggctgcctcatccggtgtgac
cccacgggaaccttctccctggctggccttggccgtccccatagcagtctccgagagctc
ttggcagcctgctgggatggcgggctgcatgtggacggggttgcgctgaacctcaccttc
tgctgcacccccaaacccaaagaaaagtccaacctgattgtggtgcggaggggttgcagc
acacccacttcatcccctgttcagccccaatcccaataccagctgaatcagatgacgttt
cacaagatccctgctgacagcctggagtggcatgagaacctgggtcacgggtccttcacc
aagatataccgaggttgtcgccacgaggtcgtggagggggaggcccgggagacggaggtg
ctgctcaaagtgatggatgccaaacataaaaactgcatggagtcatttctggaagcagcg
agtttgatgagccaagtgtcataccagcatctcgtgttgctccatggcgtgtgcatggcc
ggagacagtatcatggtacaggaatttgtacacctgggagcgctggacacctacctgcgc
aagtctggccacctggtgccagccagctggaagctgcaggtgatcaaacagctggcctat
gccctcaactatctggaagacaaaggcctcccccatggcaatgtctcagcccggaaggtg
ctcctggctcgcgaaggggctgatgggaacctgcccttcatcaagctgagtgatcctggt
gtcagcccctctgtgctaagccgggagatgctcactgacaggatcccctgggtggccccc
gagtgtctccaggaggcccggacactcggcttggaagctgacaagtggggttttggtgcc
acagtctgggaggtgttcagtgggatcccgatgcccatcagcaccctggatcccgccaag
aagctccagttttacgaggagcggcagcagctgcctgcccccaagtggatggagctggcc
atactgatccagcagtgcatggcctatgagccaggccagagaccctccttccgtgccatc
atccgtgacctgaacagcctcatcacttcagattatgagctcctctcagaccccacgccc
ggtgccttggcgccccgtgatgggctgtggaatggcgcccagctctacgcctaccaggac
cctaccatttttgaggagagacacctgaagtacatctcacagctgggcaagggcaacttc
ggcagcgtggaactgtgccgttatgaccctctgggtgacaacacgggcgccctagtggca
gtgaagcagctgcagcacagcgggccagaccagcagagggacttccggagggagatccag
atcctcaaagccctccacagcgacttcattgtcaagtaccgtggtgtcagctatggccca
ggccgccagagcctgcggctggtgatggagtacctgcccagcggctgcctgcgcgacttc
ctacagcggcaccgcgcgcgcctcgacgccagccgcctgctcctctacgcctcgcagatc
tgcaagggcatggagtacctgggctcccgccgctgcgtgcaccgcgacctggctgcgcgt
aacatcctggtggagagcgagacgcacgtcaagatcgccgactttggcctcgccaagctg
ctgccgctcgacaaagactactacgtggtccgcgagcccggccagagccccatcttctgg
tacgccccggagtccctctctgacaacatcttctcgcgccagtccgacgtctggagcttc
ggggtcgtcctgtacgagcttttcacctacggcaacaagagttgcagcccctcagccgag
ttcctgcggatgatggcatgtgatggagatgtcccggccctgtgctgcctcctggagctg
ctggctgagggccagaggctgcccgcgcctcctgcctgccctggtgaggttcatgagctc
atgaagctgtgctgggcccctagcccgcaagaccggccaacattcagtgccctgggcccc
cagctggatgcactatggagtgcaagccagggctag
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