Zalophus californianus (California sea lion): 113919723
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Entry
113919723 CDS
T07874
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04022
cGMP-PKG signaling pathway
zca04068
FoxO signaling pathway
zca04081
Hormone signaling
zca04140
Autophagy - animal
zca04152
AMPK signaling pathway
zca04211
Longevity regulating pathway
zca04213
Longevity regulating pathway - multiple species
zca04910
Insulin signaling pathway
zca04920
Adipocytokine signaling pathway
zca04923
Regulation of lipolysis in adipocytes
zca04930
Type II diabetes mellitus
zca04931
Insulin resistance
zca04932
Non-alcoholic fatty liver disease
zca04935
Growth hormone synthesis, secretion and action
zca05010
Alzheimer disease
zca05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
113919723 (IRS2)
04022 cGMP-PKG signaling pathway
113919723 (IRS2)
04152 AMPK signaling pathway
113919723 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
113919723 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
113919723 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
113919723 (IRS2)
04923 Regulation of lipolysis in adipocytes
113919723 (IRS2)
04920 Adipocytokine signaling pathway
113919723 (IRS2)
04935 Growth hormone synthesis, secretion and action
113919723 (IRS2)
09149 Aging
04211 Longevity regulating pathway
113919723 (IRS2)
04213 Longevity regulating pathway - multiple species
113919723 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
113919723 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
113919723 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
113919723 (IRS2)
04932 Non-alcoholic fatty liver disease
113919723 (IRS2)
04931 Insulin resistance
113919723 (IRS2)
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Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
113919723
NCBI-ProteinID:
XP_027445144
UniProt:
A0A6J2CN62
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Position
3:3263334..3291635
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AA seq
1328 aa
AA seq
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MASPPLHGPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGDEATAT
AGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEY
FAVAAENEQEQEGWYRALTDLVSEGRAGDAPPAAATAASCSASLPGALGGSAGAAAADDS
YGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLM
NIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPR
SKSQSSGSSSTHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRT
ASEGDGGAAAGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGARASKVALAPAGGAL
QHSRSMSMPVAHSPPAATSPSSLSSSSGHGSGSYPPPPGPHPHLQHPLHHPASQRPSSGS
ASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGELYGYMTMD
RPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFS
GSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGVALLGGG
SGSCKSDDYMPMSPTSVSAPKQILQPRAAAAAALPPTGAVVPAPTPTAGRAFPANAGSYK
TSSPAESSPEDSGYMRMWCGSKLSMENADTKLLPNGDYLNMSPSDAGTSGTPPDFFSAAL
HGSGEMLRGVPGYCYSSLPRSYKAPYTCNGDNDQYVLMSSPVGRILEEERLEPPAGPGTA
PSTSALAAAGGHTQPPHPVVPSPSRPSGSLGGRPDSFLNQRCRLVRPTRLSLEGLQTLPS
MHEYPLPPEPKSPGEYINIDFGEAAARLSPPAPPLLASAASSSSLLSASSPASSLGSGTP
GTSSDSRQRSPLSDYMNLDFSSPKSPKPGPQSGDPVGSLDAFLSPEASSPYPPLPPRPPA
PTSSLQPQPPPPPPPGELYRLPQASTSQGPSAACSSSPETGDNGDYTEMAFGVAATPPQP
IAAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRR
HSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVCLRKSSEGGGGGVLGGAEERPTSPRQ
LQPPPPQQARPRVSSQPGGLVGCPGGSGSPMRRETSAGFQNGLNYIAIDVRDEPGLSPTP
QQHPHPQPGDKSAWGRTRSLGGLISAVGGSSSGGVCGGPGPGALPSANTYASIDFLSHHL
KEATIVKE
NT seq
3987 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcatgggccccccgggccggcgggcggcgacggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgacgaggcgacggcgaca
gcgggcggggggccggcgccgcagccgccgcggctcgagtactacgagagcgagaagaag
tggcggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctgaacatc
aacaagcgcgccgacgccaagcacaagtacctgatcgcgctctacaccaaggacgagtac
ttcgcggtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctcaccgac
ctggtcagcgagggccgcgccggcgacgcgccccccgccgccgccaccgctgcgtcctgc
agcgcctccctgcccggcgccctgggcggctcggccggcgccgccgcggccgatgacagc
tacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtgaacctgaag
cccaagggcctgggccagagcaagaatctgacgggcgtgtaccgcctgtgcctgtcggcg
cgcaccatcggcttcgtgaagctcaactgtgagcagccgtcggtgacgctgcagctcatg
aacatccgccgctgcggccactcggacagctttttcttcattgaggtgggccggtcggcc
gtcacgggcccaggtgagctgtggatgcaggccgacgactcggtggtggcgcagaacatc
cacgagaccatcctggaggccatgaaggcactcaaggagctcttcgagttccggccgcgc
agtaagagccagtcgtcgggctcgtcctccacacaccccatcagcgtccccggcgcgcgc
cgccaccaccacctggtcaacctcccccccagccagacgggcctggtgcgtcgctcgcgc
accgacagcctggccgccactccgccggccgcgaagtgcagctcgtgtcgggtgcgcacg
gccagcgagggcgacggcggcgcggcggcgggggcggcgggcggcaggccagtgtcggtg
gccgggagtcccctgagccccgggccggtgcgcgcgcccctgagccgctcacacaccctg
agcggcggctgcggcgcccgcgcgagcaaggtggcgctggcgccggcagggggcgccctg
caacacagccgctccatgtccatgccggtggcgcactcgcccccagccgccaccagcccc
agcagcctgtcgtccagcagcgggcacggctccggctcctacccgccgcctccaggcccg
catccgcacctgcagcaccccctgcaccaccccgcgagccagcggccctccagcggcagc
gcctcggcctcgggctcccccagcgatcctggcttcatgtctctggatgagtacggctcc
agccctggggacctcagagccttctgcagccaccggagcaacacgcccgagtctatcgct
gagacacccccggccagggacggcagcgggggcgagctctacgggtacatgactatggac
aggcccctgagccactgtggccgcccctaccgcagagtctcgggggacggggcccaggac
ttggaccgagggctgaggaagaggacttactccctgaccacacctgcccggcagcggccg
gtaccccagccctcctctgcgtccctggatgaatacaccctgatgcgggccaccttctct
ggcagctccggccgcctctgcccgtcttgtcccgcgtcgtctcccaaagtggcctaccac
ccctatcccgaggactacggcgacatcgagatcgggtcccataggagctccagcagtaac
ctgggtgccgacgatggctacatgcccatgacccctggcgtggccctcctgggtggtggc
agcggtagctgtaagagtgatgactacatgcccatgagccccactagcgtgtcggccccg
aagcagatcctgcagcctcgagccgccgccgccgcagccctgccccccacgggagccgta
gtgccggcgcccacccccacggccggcagggcctttccagccaacgccggcagctacaag
acgagctccccagccgagagctcccccgaggacagtgggtacatgcgcatgtggtgtggc
tccaagctgtccatggagaacgcggacaccaagctgctacccaacggggactacctcaac
atgtcccccagcgacgcgggtacctcggggacccctcccgacttcttctcggccgccttg
catggcagcggggagatgctcaggggagtccctggctattgctacagctccctgccccgc
tcctacaaggctccctacacgtgcaacggggacaacgaccagtatgtgctcatgagctcc
cccgtggggcgcatcctggaagaagagaggctggaaccgccggccggcccggggaccgcg
ccgtccactagcgctctcgcggcagcaggcggccacacccagcctcctcacccagtagtg
ccttcgcccagcaggccgagtggcagcctcggtggccgccccgacagcttcctgaaccag
cgctgccggttagtgcggcccacacgcctgtccctggaggggcttcagaccctgcccagc
atgcacgagtaccctctgccgcccgagcccaagagccccggcgagtacatcaacattgac
ttcggcgaggccgcagcgcgcctgtctccgcccgcgcccccgctgctggcttcggcggcc
tcctcgtcctcgctgctgtcggccagcagcccggcctcatccctgggctcaggcaccccg
ggcaccagcagcgacagcaggcagcgctccccactctccgactacatgaacctcgacttc
agctcgcccaagtcacccaagccgggcccccagagcggggaccccgtgggctccctggat
gccttcctgtcccccgaggcctcgtccccctacccgccgctgcccccacgccctcccgcc
cccacctcctccctgcagccgcagccgcccccgccgccccccccaggggagctgtaccgc
ctgccccaggcgtccacttcccagggccccagcgctgcctgctcttcgtccccggagact
ggggacaatggggactacaccgagatggcctttggcgtagctgccaccccgccacaaccc
atcgcggcccccccgaagccggaaggtgcccgcgtgaccagccccacgtccggcctgaag
aggctgagtctcatggatcaggtgtcgggagtggaggccttcctgcaggcgagccagccc
ccagacccgcaccggggagccaaggtcatccgcgcagacccacaggggggccgccgccgc
cacagctccgagaccttctcctcgaccaccactgtgacccccgtgtccccgtccttcgcc
cataaccctaagcgccacaactcggcctctgtggaaaacgtctgtctcaggaaaagcagc
gaagggggcggtggcggcgtcctgggtggggccgaggagcgccccacctccccccgccag
ttgcagccaccgcccccccagcaggcgcgcccaagggtatcgagtcagcctgggggcttg
gttggctgcccagggggcagtggctctccaatgcgcagggagacctctgccggcttccag
aacggcctcaattacatcgccatcgacgtaagggacgagcctgggctgtcacccaccccg
cagcagcatccgcatccacagcccggagacaagagcgcctggggccggacccgcagcctc
gggggtctcatcagcgctgtggggggcagcagcagcggtggggtgtgtggggggccgggc
cctggcgccctcccctccgccaacacctatgccagcattgacttcttgtcccatcacctg
aaggaggccaccattgtgaaagagtga
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