Zalophus californianus (California sea lion): 113920032
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Entry
113920032 CDS
T07874
Symbol
IRS1
Name
(RefSeq) insulin receptor substrate 1
KO
K16172
insulin receptor substrate 1
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04022
cGMP-PKG signaling pathway
zca04068
FoxO signaling pathway
zca04081
Hormone signaling
zca04140
Autophagy - animal
zca04150
mTOR signaling pathway
zca04151
PI3K-Akt signaling pathway
zca04152
AMPK signaling pathway
zca04211
Longevity regulating pathway
zca04213
Longevity regulating pathway - multiple species
zca04722
Neurotrophin signaling pathway
zca04910
Insulin signaling pathway
zca04920
Adipocytokine signaling pathway
zca04923
Regulation of lipolysis in adipocytes
zca04930
Type II diabetes mellitus
zca04931
Insulin resistance
zca04932
Non-alcoholic fatty liver disease
zca04935
Growth hormone synthesis, secretion and action
zca04960
Aldosterone-regulated sodium reabsorption
zca05010
Alzheimer disease
zca05206
MicroRNAs in cancer
zca05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
113920032 (IRS1)
04022 cGMP-PKG signaling pathway
113920032 (IRS1)
04151 PI3K-Akt signaling pathway
113920032 (IRS1)
04152 AMPK signaling pathway
113920032 (IRS1)
04150 mTOR signaling pathway
113920032 (IRS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
113920032 (IRS1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
113920032 (IRS1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
113920032 (IRS1)
04923 Regulation of lipolysis in adipocytes
113920032 (IRS1)
04920 Adipocytokine signaling pathway
113920032 (IRS1)
04935 Growth hormone synthesis, secretion and action
113920032 (IRS1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
113920032 (IRS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
113920032 (IRS1)
09149 Aging
04211 Longevity regulating pathway
113920032 (IRS1)
04213 Longevity regulating pathway - multiple species
113920032 (IRS1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
113920032 (IRS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
113920032 (IRS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
113920032 (IRS1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
113920032 (IRS1)
04932 Non-alcoholic fatty liver disease
113920032 (IRS1)
04931 Insulin resistance
113920032 (IRS1)
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Motif
Pfam:
IRS
PH
PH_11
Motif
Other DBs
NCBI-GeneID:
113920032
NCBI-ProteinID:
XP_027445952
UniProt:
A0A6J2CTE9
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Position
3:complement(183277164..183339612)
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AA seq
1232 aa
AA seq
DB search
MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH
HDGAAAPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI
GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV
DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT
RRSRTESITATSPASMVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR
GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP
SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGSSTLTAPN
GHYILPRGGNGHRCVPGAGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTISHQKTP
SQSSVASIEEYTEMMMPAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLEMHPLDRRGGHH
RPDSSTLHTDDGYMPMSPGVAPVPSSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDP
NGYMMMSPSSSCSPDTGGGPSSSAAPSGSCYGKLWTNGVGGHHTHALPHPKLPMESGSGK
LLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGELEEGA
RHLRLSSSSGRLLYATTAEDSSSSTSSDSLGGGYCGVRPDPGLPHVHHQVLQPHLPRKVD
TAAQTHSRLARPTRLSLGDPKASTLPRVREQQQLPPLLRPPEPKSPGEYVNIEFGSDQPA
YLSGPVASCSSPSVRCPSQLQPAPREDETGTEEYMNMDLGPGRRATWQESAGVQPGSAGP
APPGAASMCRPTRAVPSSRGDYMTMQMGCPGQGYVDTSPVAPVSYADMRTGVVEEASLPG
ATAAAPSSSSAASASPTAPQKAGELVARSSLLGAPQGPGGMSAFTRVNLSPNRTQSAKVI
RADPQGCRRRHSSETFSSTPSATRAGNAVPFGGGAAVGGSGAGSSSTEDMKRHSSASFEN
VWLRPGELGGAPKEPAQVCGAAGGLENGLNYIDLDLVKDFKQRPQERPPQLPSPQPPHQP
LGSRESRSSSRSSEDLSAYASISFQKQPEDLQ
NT seq
3699 nt
NT seq
+upstream
nt +downstream
nt
atggcgagccctccggagaccgacggcttctcggacgtgcgcaaggtgggctacctgcgc
aaacccaagagcatgcacaagcgcttcttcgtgctgcgggcggccagcgaggcggggggc
ccggcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc
aaacgctcgatccccctcgagagctgcttcaacatcaacaagcgggcggactccaagaac
aagcacctggtggccctttacacccgggacgagcactttgccatcgcggcagacagcgag
gccgagcaggacagctggtaccaggccctcctgcagctgcacaaccgggccaagggccac
cacgacggggccgcggcccccggggcaggaggcggcgggggcagctgcagcggcagctct
ggccttggggaggctggggaggacttgagctacggggacgtgcccccaggacctgcgttc
aaggaggtctggcaggtgatcctgaaacccaagggcctgggtcagacaaagaacctgatt
ggcatctaccgtctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag
gcggcggccgtggtgctgcagctgatgaacatcagacgctgcggccactcagagaacttc
ttcttcatcgaagtgggccgttccgcagtgacaggacctggggagttctggatgcaggtg
gatgactctgtggtggcccagaacatgcacgagaccatcctggaggccatgcgggccatg
agcgatgagttccgtcctcgaagtaagagccagtcctcctccaactgctccaaccccatc
agcgttcccctgcgcaggcaccacctcaacaaccccccgcccagccaggtggggctgacg
cgccgctcacggactgagagcatcaccgccacctcaccggccagcatggtgggcggcaag
cagggctctttccgtgtgcgcgcgtccagcgacggcgaaggcaccatgtcccgcccggcc
tcggtggacggcagccccgtgagtcccagcaccaacaggacccacgcccaccggcatcgc
ggcagctcccggctgcacccccctctcaaccacagccgctccattcccatgccttcctcc
cgctgctcgccttccgccaccagcccggtcagcctgtcgtccagcagcaccagtggccac
ggctccacctcggactgtctcttcccgcggcggtctagtgcttctgtgtcgggttccccc
agcgatggcggcttcatctcctccgatgagtacggctccagcccttgcgatttccgaagt
tccttccgcagtgtcaccccggattccctgggccacacgccaccggcccgcggtgaggag
gagctgagcaactacatctgcatgggaggcaaagggtcctccaccctcaccgcccccaat
ggtcactacattttacctcggggtggcaacggtcaccgctgcgtcccaggtgctggcttg
ggcacgagcccagccctggctggggatgaagcagccagtgctgcagatctggataatcgg
ttccgcaagcggactcactccgcgggcacatcccctaccatttcccaccagaagacccca
tcccagtcgtctgtggcgtccattgaggaatacacagagatgatgatgcctgcctaccca
ccaggaggtggcagtggaggccggctgcctggctaccggcactctgccttcgtgcccacc
cactcctaccctgaggagggcctggaaatgcaccctttggacaggcgtgggggccaccac
cgcccagactcctccactctccacacggatgatggctacatgcccatgtccccaggagtg
gcgccagtgcccagcagccgaaagggcagtggcgactatatgcccatgagccccaagagc
gtgtcggcgccgcagcagatcatcaaccctatcagacgccatccccagagagtggacccc
aatggctacatgatgatgtccccaagcagcagctgctccccggacaccggaggcggaccc
agcagcagcgctgccccttctgggagctgctacggcaagctgtggacaaatggggtcggg
ggccaccacactcacgccctgccgcatcccaaactgcccatggagagcgggagtggcaag
ctcttgtcttgtactggtgactacatgaacatgtcgccagtgggggactccaacaccagc
agtccctccgactgctactacggcccggaggacccccagcacaagccagttctctcctac
tactcattgccaaggtcctttaagcacacccagcggcctggggagctggaggagggtgct
cggcacctccgcctttcctccagctctggccgccttctctatgctacaacagcagaagat
tcctcctcgtccaccagcagcgacagcctgggcgggggatactgtggggtgaggccggat
cctggcctcccacatgtccaccatcaggtcctgcagccccatctgcctcgaaaggtggac
acagctgcccagacccacagccgcctggctcggcccacgaggctgtccctgggggacccc
aaggccagcaccttacctcgggtccgggaacaacagcagctcccgcccctgctgcgcccc
ccagagcccaagagccccggcgaatatgtgaatattgaatttgggagtgatcagccagct
tacttatctggtcctgtggcttcctgcagctcaccttctgtcaggtgcccatcccagctc
cagccagctccccgagaggacgagactggcaccgaggaatacatgaacatggacctgggg
ccaggccggagggcgacctggcaggagagcgctggggtccagcccggcagcgcgggccct
gcaccacccggggctgctagcatgtgcaggcctacccgggcagtgcccagcagccggggg
gactacatgaccatgcagatgggttgtcctgggcagggctacgtggacacctcaccagtt
gcccccgtcagctatgccgacatgcggacaggcgttgtggaggaggccagccttccaggg
gccacggcggctgctccctcctcatcctctgcagcctctgcttctcccaccgcgcctcaa
aaagcaggggagctggtggcccgctcttccctgctgggggccccccagggacctgggggc
atgagcgccttcacccgggtgaacctcagtcccaaccgcacgcagagtgccaaagtgatc
cgtgcggacccacaagggtgccggaggcggcatagctctgagaccttctcctccacaccg
agtgctacccgggcgggcaacgcggtgccctttggagggggggctgctgtagggggcagc
ggtgctggtagcagcagcacggaggatatgaaacgccacagttctgcttcctttgagaat
gtgtggctgaggcctggggagctcgggggagcccccaaggagccggcccaagtgtgcggg
gctgctgggggtttggagaatgggcttaactacatagacctggatttggtcaaggacttc
aaacagcgccctcaggagcgcccccctcaactgccctcgccccagccccctcatcagcct
ctgggcagcagggagagccgctcaagcagccgctccagcgaggatttaagcgcctatgcc
agcatcagtttccagaagcagccagaggacctccagtag
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