KEGG   Zalophus californianus (California sea lion): 113921409
Entry
113921409         CDS       T07874                                 
Symbol
APAF1
Name
(RefSeq) apoptotic protease-activating factor 1
  KO
K02084  apoptotic protease-activating factor
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca01524  Platinum drug resistance
zca04115  p53 signaling pathway
zca04210  Apoptosis
zca04215  Apoptosis - multiple species
zca05010  Alzheimer disease
zca05012  Parkinson disease
zca05014  Amyotrophic lateral sclerosis
zca05016  Huntington disease
zca05020  Prion disease
zca05022  Pathways of neurodegeneration - multiple diseases
zca05134  Legionellosis
zca05152  Tuberculosis
zca05160  Hepatitis C
zca05161  Hepatitis B
zca05162  Measles
zca05164  Influenza A
zca05168  Herpes simplex virus 1 infection
zca05169  Epstein-Barr virus infection
zca05200  Pathways in cancer
zca05222  Small cell lung cancer
zca05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:zca00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    113921409 (APAF1)
   04215 Apoptosis - multiple species
    113921409 (APAF1)
   04115 p53 signaling pathway
    113921409 (APAF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113921409 (APAF1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    113921409 (APAF1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    113921409 (APAF1)
   05160 Hepatitis C
    113921409 (APAF1)
   05164 Influenza A
    113921409 (APAF1)
   05162 Measles
    113921409 (APAF1)
   05168 Herpes simplex virus 1 infection
    113921409 (APAF1)
   05169 Epstein-Barr virus infection
    113921409 (APAF1)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    113921409 (APAF1)
   05152 Tuberculosis
    113921409 (APAF1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    113921409 (APAF1)
   05012 Parkinson disease
    113921409 (APAF1)
   05014 Amyotrophic lateral sclerosis
    113921409 (APAF1)
   05016 Huntington disease
    113921409 (APAF1)
   05020 Prion disease
    113921409 (APAF1)
   05022 Pathways of neurodegeneration - multiple diseases
    113921409 (APAF1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113921409 (APAF1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    113921409 (APAF1)
SSDB
Motif
Pfam: Beta-prop_WDR5 Beta-prop_WDR3_1st Beta-prop_THOC3 WD40 WD40_Prp19 WD40_WDHD1_1st APAF1_C Beta-prop_WDR3_2nd WD40_CDC20-Fz Beta-prop_EML_2 WDR55 Beta-prop_TEP1_2nd EIF3I Beta-prop_WDR36-Utp21_2nd NB-ARC WD40_Gbeta Beta-prop_CAF1B_HIR1 WHD_APAF1 WD40_MABP1-WDR62_2nd Beta-prop_WDR36-Utp21_1st Beta-prop_WDR90_POC16_2nd ANAPC4_WD40 Beta-prop_EML Beta-prop_WDR75_1st Beta-prop_IFT122_1st WDR90_beta-prop_4th CARD Beta-prop_EIPR1 NBCH_WD40 Beta-prop_RIG_2nd Beta-prop_WDR41 Beta-prop_Vps41 Beta-prop_WDR19_1st Beta-prop_TEP1_C Beta-prop_Aladin WD40_MABP1-WDR62_1st RMC1_N Beta-prop_IFT140_1st Beta-prop_NUP159_NUP214 Beta-prop_WDR35_TULP_N WD40_RFWD3 WD40_like Beta-prop_HPS5 Beta-prop_VPS8 Ge1_WD40 Beta-prop_WDR11_2nd Beta-prop_DCAF12 CARD_2 Beta-prop_DCAF4 PEP5_VPS11_N Utp8_b_propeller AAA_16 Beta-prop_IFT140_2nd Beta-prop_Nup120_160 Beta-prop_ACSF4 Beta-prop_RSE1_2nd ATPase_2 Hira AAA_22 AAA_18 NPHP3_N DUF2677 nSTAND6 NACHT
Other DBs
NCBI-GeneID: 113921409
NCBI-ProteinID: XP_027447773
UniProt: A0A6J2CU39
LinkDB
Position
9:complement(22740329..22830735)
AA seq 1250 aa
MDPKARNCLLQHREALEKDIKTSYIMDRMINDGVLTVLEEEKVKNEPTQQQRAALLIKMI
LKKDNYSYISFYNALIHEGYKDLAALLHSGIPVISSSNGGKDSVGGITSYVKTVLCEGGV
PQRPVVFVTRKKLVNAIRQNLSTLNGEPGWVVIYGMAGCGKSVLAAEAVRDHFFLDGCFP
GGVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSL
LILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVSVESGLGKEKGLEILSLFV
NMKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPTRWDYYLRQLQNKQFKRIRKSSSY
DYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCLLWDMETEEVEDILQEFV
NKSLLFCDRNGKSFCYYLHDLQVDFLIEKNRGQLQDLHKKIITQFQKHYQPHTLSPDQED
CMYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELIGPAHLIHEFVEYRHILDEKDCA
VCENFQEFLSLNGHLLGRHPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDHGVLYLEWIN
KKNIKNLSRLVVRPHTDAVYHACFSEDGQRIASCGVDKTLQVFKAETGEKLLEIKAHEDE
VLCCAFSTDDRLIATCSVDKKVKIWNSLTGELVHIYDEHSEQVNCCHFTNNSHYLLLATA
SSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDVKSANERK
SINVKQFFLNSEEPQEDMEVIVKCCSWSADGARLMVAAKNKIFLFDIHTSGLLAEIPTGH
HSTIQYCDFSPQNHLAVVALSQCCVELWNMDSYLKVADCRGHLSWVHSVMFSPDGSSFLT
SSDDQTIRLWETKKVCKNSAIVLKQEIDVVFQENEVTVLAVDNIKRLQLVNGKTGQIDYL
TEAQVSCCCLSPHLQYIAFGGEDGAIEILELLNNRIFQSRIGHKKTVRHIQFTDDGKTLI
SSSDDSSIQVWNWQSEEYVFLQAHQETVKDFKLLKNSKLLSWSFDGTVKVWSIITGRIEK
DFVCHQDTVLSCDISPDATKFSSTSADKTAKIWSFDLLSPLCELRGHKGCVRCSVFSVDS
TLLATGDDNGEIRIWNVSNGELLHLCAPISVEEGAATHGGWVTDLCFSPDSKMLVSAGGY
LKWWNVVTGESSQTFYTNGTYLKKIHVSPDFKTYVTVDNLGILYILQMLE
NT seq 3753 nt   +upstreamnt  +downstreamnt
atggacccaaaagctcgaaactgtttgcttcaacatagagaagccctggaaaaggacatc
aaaacgtcctacatcatggatcgtatgattaatgatggagttttaacagtactggaggag
gaaaaagtaaaaaatgagcccactcaacagcagcgagcagctctgttaattaaaatgata
cttaaaaaagataattattcctacatatcattctacaatgctttaatacatgaagggtat
aaagatcttgctgcccttctccatagtggcattcctgtcatctcttcttccaatggtggc
aaagattcagttggtggaataacttcatatgtaaagacagtcctgtgcgaaggtggagtg
ccacagaggccggttgtttttgttaccaggaagaagctggtgaatgcaattcggcagaac
ctatccacactaaatggtgaaccaggatgggtcgtcatatatggaatggcaggttgtggg
aagtctgttttagctgcagaagctgttcgagatcattttttcttagatggttgtttccca
gggggtgtgcactgggtttcagttgggaaacaagacaaatctggacttctgatgaaattg
cagaatctttgcacacggttggatcaagatgagagtttctctcagaggcttccactcaat
attgaagaggctaaagaccgtcttcgcattctgatgctgcgcaaacacccaaggtctctg
ttgatcttggatgatgtttgggatccttgggtattaaaagcttttgacaatcagtgtcaa
attctccttacaaccagagacaagagtgttacagattcagtaatgggtcctaaatacgta
gtctctgtggagagtggcttaggaaaagaaaaaggacttgaaattttatccctttttgtt
aatatgaagaaagcagatttgccagagcaagctcacagtattataaaagaatgtaaaggt
tctcctcttgtagtgtctttaattggcgcacttttacgtgattttcccacccgttgggat
tactacctcaggcaacttcagaataagcaatttaagagaataaggaaatcttcatcttat
gattatgaggctctggatgaagccatgtctataagtgttgaaatgctcagagaggacatc
aaagattattacacagatctttctatccttcagaaggatgttaaggtgcctacaaaggtg
ttatgtcttctctgggacatggaaactgaagaagttgaagacatactgcaggagtttgtt
aataagtctctcttattctgtgatcggaatggaaaatcattttgttattatttacatgat
cttcaagtagatttccttatagagaagaatcgcggccaacttcaggatttacataagaag
ataatcactcagttccagaaacattaccagccacatactctttcaccagatcaggaggac
tgcatgtattggtacaattttctggcgtaccacatggctagtgccaatatgcacaaagaa
ctttgtgctttaatgttttctctggattggattaaagcaaaaactgaactcataggccct
gctcatctgattcatgaatttgtggaatacaggcatatattggatgaaaaggattgtgca
gtctgtgaaaatttccaggaatttttatctttaaatggacatcttcttggacgacatcca
tttcctaatattgtacagctgggtctctgtgaaccagaaacctcagaagtttatcagcaa
gctaagctgcaggccaagcaggaggtcgatcatggagttctttacctggagtggataaac
aaaaaaaacatcaagaatctttcccgcttagttgtccgcccccatacagatgctgtttac
catgcttgcttttctgaggatggtcaaagaatagcttcttgtggagttgataaaacccta
caggtgttcaaagctgaaacaggagagaaactgctggaaatcaaggctcatgaggatgaa
gtgctttgttgtgcattctctacagatgacagattaatagcaacctgctcagtggataaa
aaagtgaagatttggaattctctgacgggggaactagtacatatctatgatgagcactca
gagcaagtcaactgctgccactttaccaacaacagtcattaccttctcttagccactgcg
tcaagtgactgcttcctcaaactctgggatttgaatcaaaaagaatgtcgcaataccatg
tttggccacacaaattcagtcaatcactgcagattttcaccagatgataagcttttggct
agttgttcagctgatggaacattaaagctttgggatgtgaaatcagcaaacgagaggaaa
agcattaatgtgaagcagttcttcttaaattcagaggagcctcaagaggatatggaagtg
atagtgaaatgctgttcatggtctgctgatggtgctaggctaatggtggcagcaaaaaat
aaaatctttctttttgacattcataccagtggcttattggcagaaatccctacaggccat
cacagcaccatccagtattgtgacttctccccgcaaaatcatttggcagtggtggctttg
tcccagtgctgtgtggagttgtggaatatggactcgtatttaaaagtggctgattgcaga
ggacatctaagttgggttcattctgtgatgttttctcctgatggatcatcatttttgaca
tcttctgatgaccagacaatcaggctctgggagacaaaaaaagtatgtaagaattctgct
attgtgttaaagcaagaaatagatgttgtgtttcaagaaaatgaagtgacggttcttgca
gttgacaatataaaacgtctgcagctcgttaatggaaaaacaggtcagattgattatctg
actgaagctcaagttagttgctgttgcctaagtccacatcttcagtacattgcatttgga
ggtgaagatggagccattgagattttagagctcctaaacaacagaatcttccaatccagg
attggacacaagaaaactgtgcggcacatccagttcacagatgatgggaagactcttatt
tcaagctctgatgattcttcaattcaggtatggaattggcaatcagaagaatatgtcttt
ctacaagcccaccaggaaacagtgaaagactttaagctcttgaaaaattcaaaactgctt
tcctggtcatttgatggaacagtgaaggtatggagtattattactggaagaatagaaaaa
gactttgtctgtcaccaggatacggtactttcttgtgatatttctcctgatgctaccaag
ttttcatctacatctgctgataagactgcaaagatttggagttttgaccttctttcccct
ctttgtgaattgaggggccacaaaggttgtgtgcgctgctctgtcttctctgtggacagt
accctgttggcgactggagatgacaatggagaaatccggatatggaatgtctcaaatggt
gagctgcttcatttgtgtgctccgatttcagtagaagaaggagctgctacccacggaggc
tgggtgactgacctttgcttttctccagatagcaaaatgcttgtctctgctggaggatat
cttaagtggtggaatgttgtcactggggaatcctcacagaccttctacacaaatggaacc
tatcttaagaaaatacatgtgtcccctgacttcaaaacatatgtgactgttgataatctt
ggtattttatatattttacagatgttagaataa

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