Zalophus californianus (California sea lion): 113923473
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Entry
113923473 CDS
T07874
Symbol
HK1
Name
(RefSeq) hexokinase-1 isoform X1
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca00010
Glycolysis / Gluconeogenesis
zca00051
Fructose and mannose metabolism
zca00052
Galactose metabolism
zca00500
Starch and sucrose metabolism
zca00520
Amino sugar and nucleotide sugar metabolism
zca00524
Neomycin, kanamycin and gentamicin biosynthesis
zca01100
Metabolic pathways
zca01200
Carbon metabolism
zca01250
Biosynthesis of nucleotide sugars
zca04066
HIF-1 signaling pathway
zca04910
Insulin signaling pathway
zca04930
Type II diabetes mellitus
zca04973
Carbohydrate digestion and absorption
zca05230
Central carbon metabolism in cancer
Module
zca_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
zca_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
zca_M01015
GDP-Man biosynthesis, Man => GDP-Man
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
113923473 (HK1)
00051 Fructose and mannose metabolism
113923473 (HK1)
00052 Galactose metabolism
113923473 (HK1)
00500 Starch and sucrose metabolism
113923473 (HK1)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
113923473 (HK1)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
113923473 (HK1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
113923473 (HK1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
113923473 (HK1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
113923473 (HK1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
113923473 (HK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
113923473 (HK1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
zca04131
]
113923473 (HK1)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
113923473 (HK1)
Membrane trafficking [BR:
zca04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
113923473 (HK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Sec23_helical
UvrD-helicase
Motif
Other DBs
NCBI-GeneID:
113923473
NCBI-ProteinID:
XP_027452072
UniProt:
A0A6J2DB78
LinkDB
All DBs
Position
15:30623780..30737681
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AA seq
917 aa
AA seq
DB search
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFKKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQNVHMESEIYDTPENIVH
GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEGILITWTKKFKASGV
EGMDVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKESLLFEGRITPELLTRGKFKTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCISVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQFSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFRLT
KDMLLEVKKRMRAEMDMGLRKQTHEKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPKMPLGF
TFSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLREAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMLEGNDGRMCINMEWGAFGDNGCLDD
IRTIYDRLVDEYSLNAGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG
IFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA
VVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMYQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLREETSS
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
atgatcgccgcgcagctcctggcctattacttcaccgagctgaaggatgaccaagtcaaa
aagattgacaagtatctctatgccatgcggctctccgatgaaactctgatagatatcatg
actcgtttcaagaaggagatgaagaatggcctctcccgggattttaatccaacagccaca
gtcaagatgttgccaacgtttgtaaggtccatccctgatggttcagaaaagggagatttc
attgccctggatcttggcgggtcttcctttcgaattctgagggtgcaagtgaatcatgag
caaaaccagaatgttcacatggagtccgagatttacgacaccccggagaacatcgtgcac
ggcagtggaagccagctttttgatcacgtggctgagtgcctgggagactttatggagaaa
aaaaaaatcaaggacaagaaattacctgtgggattcacgttttctttcccttgtcggcag
tccaaaatagacgagggcatcctgatcacctggacaaagaaatttaaagcgagtggagtg
gagggaatggatgtggtgaagctgcttaacaaagccatcaaaaagcgcggggactatgat
gccaacattgtggccgtggtgaacgacacggtggggaccatgatgacctgtggctatgat
gaccagcagtgtgaagtcggcctcatcattggcactggcaccaatgcctgctacatggag
gaactgaggcacattgacctggtggaaggcgatgaggggaggatgtgcatcaacacagaa
tggggggcattcggggacgacgggtccctggaagatatccgcaccgagtttgaccgagag
atagaccgtggctccctcaaccctgggaagcagctgtttgagaagatggtcagtggcatg
tacttgggggagctggtgcgactgatcctggtcaagatggccaaggagagcctcttattt
gaagggcggattaccccggagctgctcaccagggggaagttcaagaccagcgatgtgtca
gccattgagaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga
gtggagccatccgatgacgactgtatttcagtccagcacgtgtgtaccattgtctcattt
cgctctgccaacctggtggctgcaacgctgggcgccatcttgaaccgccttcgagataac
aagggcacacccaggctgcggaccacggttggtgtcgacgggtctctttacaagacgcac
ccacagttttcccggcgtttccacaagactctgaggcgcttggtgcccgactccgatgtg
cgtttcctcctctcggagagcggcagcggcaaaggggccgccatggtcaccgcggtggcc
taccgcctggcggagcagcaccgacagattgaggagaccctggcccacttccgcctcacc
aaggacatgctgctggaggtgaagaagagaatgcgggctgagatggatatgggcctgagg
aagcagacgcacgagaaggccgtggtcaagatgctgccctcctttgtccggagcactcca
gatgggaccgagcatggtgacttcttggcccttgatcttggaggaacaaatttccgtgtc
ctgctggtgaaaatccgcagtgggaaaaagagaacggtggaaatgcacaacaagatctat
gccatccccattgaaatcatgcagggcaccggggaagagctgtttgaccacatcgtctcc
tgcatctctgacttcctggactacatggggatcaaaggccccaagatgcctctgggcttc
acgttctcattcccctgcaagcagacgagcctggatgcgggaatcttgatcacctggaca
aagggttttaaggcaactgactgcgtggggcacgatgtagcaacattactaagggaagca
ataaaaaggagagaggaatttgacctggacgtggtggctgtggtcaatgacacggtgggc
accatgatgacctgtgcttacgaggagcctacctgcgaggttggactcatcgtagggacc
ggcagcaatgcctgctacatggaagaaatgaagaacgtcgagatgctggaggggaatgat
gggcgcatgtgcatcaacatggagtggggtgcctttggggacaacgggtgtctagatgat
atcagaacaatctacgacagactggtagatgaatattctctaaacgctgggaaacaaagg
tttgagaagatgattagcggtatgtacctgggtgagatcgtccgcaacatcttgatcgac
ttcaccaagaaggggttcctcttccgagggcagatctctgagacgctgaagacccggggc
atctttcagaccaaatatctttcccagattgagagtgaccggttagcgctgctccaggtc
cgggccatcctccagcagctgggcctgaacagcacctgtgacgacagtatcctggtcaag
accgtgtgcggggtggtgtccaagagggctgcacagctgtgtggtgcgggcatggctgcc
gtggtggataagatccgcgagaacagagggctggaccacctcaatgtgactgtgggcgtg
gatggaacactctacaagcttcatccgcacttctccagaatcatgtaccaaaccgtgaag
gaactgtcccccaaatgtaacgtgtccttcctcctgtccgaagacggtagcggcaagggg
gctgctctcatcacggcagtgggcgtccggctccgggaagagacgagcagctaa
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