Zalophus californianus (California sea lion): 113932258
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Entry
113932258 CDS
T07874
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04064
NF-kappa B signaling pathway
zca04380
Osteoclast differentiation
zca04650
Natural killer cell mediated cytotoxicity
zca04658
Th1 and Th2 cell differentiation
zca04659
Th17 cell differentiation
zca04660
T cell receptor signaling pathway
zca05135
Yersinia infection
zca05166
Human T-cell leukemia virus 1 infection
zca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
zca05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
113932258 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
113932258 (LCK)
04660 T cell receptor signaling pathway
113932258 (LCK)
04658 Th1 and Th2 cell differentiation
113932258 (LCK)
04659 Th17 cell differentiation
113932258 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
113932258 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113932258 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113932258 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
113932258 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
113932258 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113932258 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
zca03036
]
113932258 (LCK)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
113932258 (LCK)
Protein kinases [BR:
zca01001
]
Non-receptor tyrosine kinases
SRC family
113932258 (LCK)
Chromosome and associated proteins [BR:
zca03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
113932258 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH2_1
Haspin_kinase
Kdo
SH3_16
Motif
Other DBs
NCBI-GeneID:
113932258
NCBI-ProteinID:
XP_027466890
UniProt:
A0A6J2ED96
LinkDB
All DBs
Position
4:24368012..24393336
Genome browser
AA seq
509 aa
AA seq
DB search
MGCSCSSNPEDDWMENIDVCENCHYPIVPLDSKATLPMWNGSDVRDPLVTYEGSNPPASP
LQDNLVIAKYSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGEEGFIPFNFVVKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDKGGFYITPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYKGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLHAVVTQEPIYIITEYMENGSLVDFLKTPAGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKEH
PEERPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtatgt
gagaactgccattaccccatagtcccactggacagcaaggccacgctgcccatgtggaat
ggctctgacgtgcgggatccactggttacctacgaaggctccaaccccccagcctcacca
ttgcaagataacctggttatcgctaagtacagctatgagccctctcacgatggagacttg
ggcttcgagaagggtgaacagctccggatcctggagcagaacggcgagtggtggaaggcg
cagtccctgaccacgggcgaggaaggcttcatccccttcaacttcgtggtcaaagcgaac
agcctggagccggaaccctggttcttcaagaacctgagccgcaaggacgctgagcggcag
ctcctggcgcccgggaacacgcacggctccttcctgatccgggagagcgagagcaccgcg
ggatcgttctcactgtccgtgcgggacttcgaccagaaccagggagaggtggtgaaacat
tacaaaatccgtaacctggacaaaggcggcttctacatcactccccgcatcacttttcct
ggcttgcacgagctggtccgccattacaccaatgcttcggacgggctgtgcacgcggttg
agtcgcccctgccagacccagaagccccagaagccttggtgggaggacgagtgggaggtt
cccagggagacgctgaagctggtggagcggctgggggctggccagttcggggaggtgtgg
atggggtactacaaggggcacacaaaggtggcagtgaagagcctgaagcagggcagcatg
tcccccgacgccttcctggccgaggccaacctcatgaagcagctgcaacaccagagactg
gtccggctccacgcggtggtcacccaggagcccatctacatcatcacggaatacatggag
aacgggagcctggtggatttcctcaagacccccgcaggcatcaagctgaccatcaacaaa
ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagaacggaactat
atccatcgtgacctgagggctgccaacatcctggtatctgacaccctgagctgcaagatt
gcagactttggcctagcacgcctcatcgaggacaacgagtacacagccagggagggagcc
aagtttcccattaagtggacagcaccagaagccattaactacgggacattcaccatcaag
tcagacgtgtggtcttttgggatcctgctgacggagattgtcacccacggccgcatccct
tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggtg
cgacctgacaactgtcccgaggagctgtaccacctcatgatgctgtgctggaaggagcac
ccagaggaacggcccacctttgactacctgcgcagtgtgctggaggacttcttcacagcc
acagagggccagtaccagccccagccctga
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