Zalophus californianus (California sea lion): 113933533
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Entry
113933533 CDS
T07874
Symbol
PSEN2
Name
(RefSeq) presenilin-2 isoform X1
KO
K04522
presenilin 2 [EC:3.4.23.-]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04330
Notch signaling pathway
zca04722
Neurotrophin signaling pathway
zca05010
Alzheimer disease
zca05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
113933533 (PSEN2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
113933533 (PSEN2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
113933533 (PSEN2)
05022 Pathways of neurodegeneration - multiple diseases
113933533 (PSEN2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
zca01002
]
113933533 (PSEN2)
Peptidases and inhibitors [BR:
zca01002
]
Aspartic peptidases
Family A22: presenilin family
113933533 (PSEN2)
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Gene cluster
GFIT
Motif
Pfam:
Presenilin
Motif
Other DBs
NCBI-GeneID:
113933533
NCBI-ProteinID:
XP_027469535
UniProt:
A0A6J2EKN6
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Position
10:complement(66486529..66512007)
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AA seq
500 aa
AA seq
DB search
MIFPSRDFKVLSGFSSDLEARGVLCSPEPGTSQGRAMLTFMASDSEEEVCDERTSLMSAE
SPPPRCCQEARQGLEDGENAAQWRSQDSEEDLDDADRYVCSGVPGQPLGLEEELTLKYGA
KHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLPYGAGREQSLQPAISLSIYTPFTEDT
PSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYL
GEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLP
EWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLD
PSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLPGSPEGELEEEEERGVKLGLGDFI
FYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYF
STDNLVRPFMDTLASHQLYI
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atgattttcccctccagagatttcaaagtgctgtcaggcttcagttctgacttggaagca
agaggcgtgctgtgttctccagagccaggcacttcccaaggcagggccatgctcacgttc
atggcctctgacagtgaggaagaagtgtgtgacgagaggacgtccctgatgtcggctgag
agcccgccaccacgctgctgccaggaggcgcggcagggcctggaggacggagagaatgct
gcccagtggagaagccaggatagtgaggaggacctcgacgacgcggaccgctacgtgtgc
agtggggtccctgggcagccgttgggcctggaggaggagctgaccctcaaatacggggca
aagcatgtgatcatgctgtttgtgcctgtcacgctgtgcatgattgtggtggtggccacc
atcaagtccgtgcgcttctacacggagaagaacggccagctgccctatggagcaggcagg
gagcagagtctgcagcccgccatctccctcagcatctacacaccattcactgaggacacg
ccctccgtgggccagcgcctgctcaactctgtgctcaacaccctcatcatgatcagcgtc
atcgtggccatgaccatcttcctggtcgtcctctataagtaccgctgctacaagttcatc
cacggctggttgatcatgtcctccctgatgctgctatttctcttcacctatatctacctc
ggggaagtgctcaagacctacaacgtggccatggactaccccaccctgttcctgaccgtc
tggaacttcggggcagtgggcatggtgtgcatccattggaaaggccccttggtgctgcag
caggcctacctcatcatgatcagtgcgctcatggccttggtattcatcaagtacctccca
gagtggtccgcgtgggtcattctgggcgccatctctgtgtacgatcttgtggctgtgctg
tgccccaaagggccactgaggatgctggtggagactgcccaggagagaaacgagcccata
tttcccgccctgatatactcctctgccatggtgtggacggtgggcatggccaagctggac
ccctcctcccagggagcccttcagctgccctatgaccccgagatggaagaagactcctat
gacagttttggggagccctcatacccagaagtctttgagccccccctgcctggttcccca
gagggggagctggaggaagaggaggaaaggggcgtgaagctcggcctgggggacttcatc
ttctacagcgtgctggtgggcaaggcggcagccaccggcagcggggactggaacaccact
ctggcatgcttcgtggccatcctcattggtttgtgtctgaccctcctgctgcttgctgtg
ttcaagaaggcgctgcccgctctccccatctccatcacttttgggctcatcttctacttc
tccacggacaacctggtgcgtccgttcatggacaccttggcctctcatcagctctacatc
tga
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