Zalophus californianus (California sea lion): 113937583
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Entry
113937583 CDS
T07874
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04120
Ubiquitin mediated proteolysis
zca04144
Endocytosis
zca04330
Notch signaling pathway
zca04668
TNF signaling pathway
zca04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
113937583 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
113937583 (ITCH)
04668 TNF signaling pathway
113937583 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
113937583 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
113937583 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
zca04131
]
113937583 (ITCH)
04121 Ubiquitin system [BR:
zca04121
]
113937583 (ITCH)
Enzymes [BR:
zca01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
113937583 (ITCH)
Membrane trafficking [BR:
zca04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
113937583 (ITCH)
Ubiquitin system [BR:
zca04121
]
Ubiquitin ligases (E3)
HECT type E3
113937583 (ITCH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
113937583
NCBI-ProteinID:
XP_027477882
UniProt:
A0A6J2FFD5
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All DBs
Position
8:115712043..115830303
Genome browser
AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGETTCSESASQNDDGSRPKDETRTNTNGS
DEPEDAGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESE
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNSVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagtagacggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccaacagagacaataggagacttgtcagtttgtcttgat
gggctgcagttggagtctgaagttgttaccaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagaacaaacacaaatggatca
gatgagcctgaggatgcaggggctggtgaaaataggaaggtcaatgggaataattctcca
tcactctcaaatggtggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgag
ggatccagtacaggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctctgactatatctggaggctcaggccctaggccattaaat
tctgtacctcaggctcccctaccacctggttgggagcagagagtggaccagcatggacga
gtttactatgtagatcatattgaaaaaagaacaacctgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttactatgttgaccatttcaca
agaacaacaacgtggcagagaccaacgctggaatctgtccggaactatgaacagtggcag
ctccagcgtagtcagctgcaaggagcaatgcagcagtttaaccagagatttatttatggg
aatcaagatttgtttactacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaagtcaaggccaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagttgatggaattccatattttgtggaccacaataga
agaacaaccacctatattgatccccgcactggaaaatctgccctagacaatggaccacag
atagcctatgtacgggacttcaaggcaaaagttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaagacattgtttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
cacgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaagataactactgc
ttgcagattaatcctgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggaaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacctgccggttgccagttggagga
tttgctgacctcatggggagcaatggaccacaaaaattctgcattgaaaaagttggaaaa
gaaaattggttgcccagaagtcatacgtgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaagaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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