Zalophus californianus (California sea lion): 113937908
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Entry
113937908 CDS
T07874
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04137
Mitophagy - animal
zca04140
Autophagy - animal
zca04141
Protein processing in endoplasmic reticulum
zca04210
Apoptosis
zca04932
Non-alcoholic fatty liver disease
zca05010
Alzheimer disease
zca05012
Parkinson disease
zca05014
Amyotrophic lateral sclerosis
zca05020
Prion disease
zca05022
Pathways of neurodegeneration - multiple diseases
zca05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
113937908 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
113937908 (EIF2AK3)
04137 Mitophagy - animal
113937908 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
113937908 (EIF2AK3)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
113937908 (EIF2AK3)
05012 Parkinson disease
113937908 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
113937908 (EIF2AK3)
05020 Prion disease
113937908 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
113937908 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113937908 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
113937908 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113937908 (EIF2AK3)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
113937908 (EIF2AK3)
Protein kinases [BR:
zca01001
]
Serine/threonine kinases: Other
PEK family [OT]
113937908 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
ABC1
Kdo
DUF7670
EMC1_C
Motif
Other DBs
NCBI-GeneID:
113937908
NCBI-ProteinID:
XP_027478651
UniProt:
A0A6J2FCZ7
LinkDB
All DBs
Position
8:38760616..38829908
Genome browser
AA seq
1114 aa
AA seq
DB search
MERATRPGRLARALLLLLLLLGLAPGTVAAGRAPDLPAPKAEAAFGLGAAAAPTSAARVP
AAGAVVTAEVTVEDAEAVPAAATEQEPRDPEPDDEAELRPRGRSLVIISTLDGRIAALDP
ENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVES
LLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDDMEQEDILLLQRS
QKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGSKEGSKIISDVEEQ
EATMMDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDTSY
ASNNEVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNNEY
AIMPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYY
LPYYKRERSKRSTQISVRFLENPSYNKNIRKKDPVLLLHWWKEIVGTILFCIIATTFIVR
RLFHPHPHRQRKESETQCQTESKYDSVSGEAKDSSWNDIKNSGYVSRYLTDFEPVQCMGR
GGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLDHPGIVRYFNAWLEA
PPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFSTKEHIEIIAPSSQRRSF
SVGISCGQTSSSESQFSPLEFSGMDHGDTSESMDAACNLQDSCLTECDVEDGTMDGNDKA
NSFELCPSGTSLYERSREKTSSSIVFEDSGCDNTSSKEELKTKRLHIGNHCANKLTAFKH
SSNKSSSKPTFSVSPPRPTTLSLDLTKNTAEKLQPSSPKVYLYIQMQLCRKENLKDWMNS
RCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTVDDVVKVGDFGLVTEM
DQDEEEQMVLTPMPAYARHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPFG
TQMERVRILTDVRNLKFPPLFTQKYPREYVMVQDMLSPSAMERPEATTIIENAVFEDLEL
PGKTVLRQRSRSLSSSGTKHSRHSSNSRSPLPSN
NT seq
3345 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccacccgcccggggcggctcgcacgggcgctgctgctgctgctgctgctg
ctgggactggctccgggcacggtggccgcggggcgcgccccggacctccccgcgccgaag
gcggaggcggcgttcggcctgggcgcagcggccgctcccacttctgcagcgcgggtgccg
gcggcaggggccgtggttacggccgaagtgacggtggaggacgccgaagctgtgccggcg
gccgctacggagcaggagccgcgggacccggaacccgacgacgaggccgaactacggccg
cgcggcagatcattagtgattatcagcactttagatgggcgaattgctgccttggatcct
gagaatcatggtaaaaaacagtgggatttggatgtgggatccggttccttggtttcatcc
agcctcagcaaaccagaggtatttgggaataagatgatcatcccttctctggatggagac
ctcttccagtgggaccgggaccgtgagagcatggaaacagttccttttacagttgaatca
cttcttgaatcttcttataaatttggagatgatgttgttttggttggaggaaagtctctc
acgacatatggactcagtgcatacagtggaaaggtgaggtacatctgttcagctttgggt
tgtcgccaatgggataatgatgatatggaacaagaagacatcctgcttttgcaacgctcc
cagaaaacggttagggctgtcggacctcgcagtggcaatgagaagtggaatttcagtgtt
ggccactttgaacttcggtatattccagacatggaaactagagccggatttattgaaagc
accttaaagcccagtgggagcaaagaagggtctaaaattatttcagatgttgaagaacag
gaagccaccatgatggacacagtgataaaggtctcagttgctgactggaaggttatggcg
tttagcaagaagggaggacatctggaatgggaataccagttttgtacccccattgcatct
gcttggttggttaaggatggaaaagtcattcccatcagtcttttcgatgatacaagttat
gcatctaacaatgaagtgttagaagatgaagaagacattgtagaagctgctcgaggagcc
acagaaaacagcgtttacctgggaatgtacagaggtcagctgtatctgcagtcatcagtc
agaatttcagaaaagtttcctacaagtcccaaggccttggaatctgtcaataatgagtat
gcaattatgcctttgccaacaatcaaatggaaacccttaattcattctccttccagaact
cctgtcttggtagggtctgatgaatttgacaaatgtcttagtaacgataaattttctcat
gaagagtacagtaatggcgccctttccatcttgcaatacccatatgataatggttattat
ctaccttactacaagagggagaggagcaaacggagcacacagatctcagtccgatttctc
gagaacccaagttacaacaagaacattcgcaaaaaggatcctgttctcctcttacactgg
tggaaagaaatagttggaactattctgttttgtatcatagcaacaacttttattgtgcgt
agacttttccatccccatcctcacagacaaaggaaggaatctgaaactcagtgtcaaact
gaaagtaaatatgactctgtcagtggagaagctaaggacagtagctggaatgacattaaa
aattctggatatgtatcacgctatctaacagattttgaaccagttcagtgcatgggtcgt
ggtgggtttggagtcgtctttgaagccagaaacaaagtagatgactgcaattatgctatc
aagagaattcgcctccccaacagggagttggctcgggaaaaggtaatgagagaagttaaa
gccttagccaagcttgaccatccagggattgttagatatttcaatgcttggttggaagca
ccaccagagaagtggcaagaaaaaatggatgaaatttggctgaaagatgaaagcacagac
tggccactcagctctcctagtccaatggatgcaccgtcggttaaaatacgcagaatggat
cctttctctacaaaggaacatattgaaatcatagctccttcttcacaaaggaggtctttt
tcagtagggatttcctgtggccagacgagttcatctgagagtcagttctctccgctggaa
ttttcaggaatggaccatggagataccagtgagtccatggatgcagcatgcaacctccaa
gacagttgtcttacggaatgcgatgtggaagatggtactatggatggcaatgataaggcg
aactcctttgaactttgtccttctggaacttctctttatgaaaggtcaagggagaaaaca
tcctcttctatagtatttgaagattctggctgtgataacacgtccagtaaagaagagctc
aaaacgaagcgactgcatattggcaaccattgtgctaataaactaactgctttcaagcat
tccagtaacaaatcttcttctaaacctactttctctgtttctcctccaagaccgaccact
ttaagtttagatctcactaaaaacactgcagaaaaactccagcccagttccccaaaggta
tatctttacattcagatgcagctctgcagaaaggaaaacctcaaagactggatgaacagc
cgatgcaccatagaggagagagagagaagcgtgtgtctgcacatcttcctgcagattgca
gaggccgtagagtttctgcacagtaaagggctcatgcacagggacctcaagccttccaac
atattctttacagtggatgatgtggtcaaggttggagactttggattggtgactgaaatg
gaccaggatgaggaagagcagatggttctgaccccaatgccagcatatgccagacacaca
ggacaagtggggaccaagctatatatgagcccagagcagattcatggaaacaactactct
cataaagtggacatcttttctctaggcctcattctgtttgaattgctgtacccattcggc
actcagatggagagagtcaggatcttaactgacgtaagaaatctcaaatttccaccacta
tttactcagaaatatcctcgtgagtatgtgatggttcaagacatgctctctccatccgcc
atggaacggcctgaagctaccaccatcattgaaaatgctgtatttgaagacttggagctt
ccaggaaaaacagtactcagacagaggtctcgctccctgagttcatcgggaacaaaacat
tcaagacattccagcaactcccggagccctttgccaagcaattag
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