 Eukaryotic type
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SSBR (single strand breaks repair)
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 Direct repair
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BER (base exicision repair)
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DNA glycosylases
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AP endonucleases
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Long Patch-BER factors
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DNA polymerase delta complex
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 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
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DNA polymerase epsilon complex
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K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
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K04802 PCNA; proliferating cell nuclear antigen
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K04799 FEN1, RAD2; flap endonuclease-1 [EC:3.1.-.-]
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K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
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Short Patch-BER factors
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K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K10803 XRCC1; DNA-repair protein XRCC1
K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
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Other BER factors
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NER (nucleotide excision repair)
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GGR (global genome repair) factors
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TCR (transcription coupled repair) factors
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DNA-directed RNA polymerase II complex
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Cul4-CSA complex
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Other TCR factor
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K10841 ERCC6, CSB, RAD26; DNA excision repair protein ERCC-6
K23720 UVSSA; UV-stimulated scaffold protein A
K25829 ELOF1, ELF1; transcription elongation factor 1
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TFIIH complex
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RPA (replication factor A)
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Other NER factors
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K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K10848 ERCC4, XPF; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10846 ERCC5, XPG, RAD2; DNA excision repair protein ERCC-5
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K15075 MET18, MMS19; DNA repair/transcription protein MET18/MMS19
K27967 CCDC117; coiled-coil domain-containing protein 117
K24730 CIAO1, CIA1; cytosolic iron-sulfur protein assembly protein CIAO1
K26403 CIAO2, CIA2, FAM96; cytosolic iron-sulfur assembly component 2
K03869 CUL3; cullin 3
K10612 CUL5; cullin 5
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K15076 ELOA, TCEB3; elongin-A
K15077 ELA1; elongin-A
K26545 UBAP2; ubiquitin-associated protein 2
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MMR (mismatch excision repair)
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Mismatch and loop recognition factors
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K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
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MutL homologs
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K10864 PMS1; DNA mismatch repair protein PMS1
K08734 MLH1; DNA mismatch repair protein MLH1
K10858 PMS2; DNA mismatch repair protein PMS2
K08739 MLH3; DNA mismatch repair protein MLH3
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DNA polymerase delta complex
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RPA (replication factor A)
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RFC (replication factor C)
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Other MMR factors
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DSBR (double strand breaks repair)
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HR (homologous recombination)
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NHEJ (non-homologous end-joining)
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FA (Fanconi anemia) pathway
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Other DSBR factors
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Protein phosphatase 6
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Ubiquitin ligases
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Others
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K23314 WRAP53, TCAB1; telomerase Cajal body protein 1
K24164 TPRN; taperin
K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1
K24752 WDR70; WD repeat-containing protein 70
K24755 WDR76, CMR1; WD repeat-containing protein 76
K28434 HMCES; abasic site processing protein HMCES
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TLS (translesion DNA synthesis) factors
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Check point factors
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Other factors with a suspected DNA repair function
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Prokaryotic type
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SSBR (single strand breaks repair)
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Direct repair
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BER (base exicision repair)
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NER (nucleotide excision repair)
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GGR (global genome repair) factors
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TCR (transcription coupled repair) factors
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DNA-directed RNA polymerase complex (RNAP)
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K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
K13797 rpoBC; DNA-directed RNA polymerase subunit beta-beta' [EC:2.7.7.6]
K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
K03048 rpoE; DNA-directed RNA polymerase subunit delta
K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
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TRCF (transcription-repair coupling factor)
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K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
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MMR (mismatch excision repair)
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Mismatch and loop recognition factors
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K03555 mutS; DNA mismatch repair protein MutS
K07456 mutS2; DNA mismatch repair protein MutS2
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Molecular matchmaker
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K03572 mutL; DNA mismatch repair protein MutL
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Strand discrimination factor
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K03573 mutH; DNA mismatch repair protein MutH
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DNA exonucleases
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DNA polymerase III holoenzyme
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DNA ligase
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Other MMR factors
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K03657 uvrD, pcrA; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
K03111 ssb; single-strand DNA-binding protein
K06223 dam; DNA adenine methylase [EC:2.1.1.72]
K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
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DSBR (double strand breaks repair)
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TLS (translesion DNA synthesis) factors
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Other factors with a suspected DNA repair function
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DNA Repair and Recombination Proteins