| Entry |
Name |
Description |
Object |
Legend |
|
hsa03060
|
Protein export |
The protein export is the active transport of proteins from the cytoplasm to the exterior of the cel... |
5018 (OXA1L) 6727 (SRP14) 6731 (SRP72) 6730 (SRP68) 6729 (SRP54) 6728 (SRP19) 6734 (SRPRA) 6726 (SRP... |
...I SRP14 SRP72 SRP68 SRP54 SRP19 SRPR SRP9 SecB PROTEIN EXPORT Sec dependent pathway Signal peptidase... |
|
hsa04141
|
Protein processing in endoplasmic reticulum |
...eticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperon... |
G00010 C00076 (Calcium cation) G00010 G00009 G00011 G00011 G10694 G00012 468 (ATF4) 1649 (DDIT3) 559... |
...PROCESSING IN ENDOPLASMIC RETICULUM Protein export Apoptosis Proteasome ATF4 CHOP JNK TRAF2 ASK1 ... |
|
hsa02010
|
ABC transporters |
...BC) transporters form one of the largest known protein families, and are widespread in bacteria, arc... |
... C00378 (Thiamine) C06767 (Hemine) C01834 (Lipoprotein) C01330 (Sodium cation) C06706 (Lipo-oligosac... |
...family ABCD Subfamily ABCG Subfamily Macrolide exporters Other putative ABC transporters HlyB α-Gluc... |
|
hsa03013
|
Nucleocytoplasmic transport |
...uclear transport receptors (e.g. importins and exportins) mediate translocation of cargos through th... |
11260 (XPOT), 1434 (CSE1L), 23039 (XPO7), 23214 (XPO6), 57510 (XPO5), 64328 (XPO4), 64901 (RANBP17),... |
... Nup Nup 214 DDX Rae1 Nup62 complex NPC Import Export mRNA Export Importin Importin NLS NLS Ran GTP ... |
|
hsa04068
|
FoxO signaling pathway |
...gevity. A central regulatory mechanism of FOXO proteins is phosphorylation by the serine-threonine k... |
C00031 (D-Glucose) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00008 (ADP) C00020 (AMP) C0002... |
IKKα/β JNK ERK1/2 AMPK INS Glucose FOXO SOS Ras MEK1/2 INSR Raf PEPCK G6PC Akt P13K PDK1/2 IRS PIP F... |
|
hsa03008
|
Ribosome biogenesis in eukaryotes |
... the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves... |
100008588 (RNA18SN5), 106631781 (RNA18SN1), 109864273 (RNA18SN4), 109864280 (RNA18SN2), 109910380 (R... |
...fication UTP24 Rnt1 KRE33 UTP14 Bms1 Ribosomal proteins 18S Rcl1 18S HRR25 DEAD-box helicases Mrp ... |
|
hsa05164
|
Influenza A |
...t among influenza viruses and two surface glycoproteins HA and NA form the basis of serologically di... |
C00080 (H+) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00027 (Hydrogen peroxide) 23430 (TPSD... |
...L-R ANT3 VDAC1 Importin PB1 PB2 CRM1 Viral RNP export PKCα Raf MEK1/2 ERK1/2 Viral protein expressio... |
|
hsa05130
|
Pathogenic Escherichia coli infection |
...Map, EspF, EspG are known LEE-encoded effector proteins secreted via the type III secretion system, ... |
C00350 (Phosphatidylethanolamine) C00681 (1-Acyl-sn-glycerol 3-phosphate) C00338 (Lipopolysaccharide... |
...estinal tract Kidney ....... Inhibition of protein synthesis Pedestal formation EspG2 Bfp Arp2/3... |
|
hsa03015
|
mRNA surveillance pathway |
...of the poly(A) tail. NSD involves an eRF3-like protein, Ski7p, which is hypothesized to bind the emp... |
5976 (UPF1) 26019 (UPF2) 65109 (UPF3B), 65110 (UPF3A) 23049 (SMG1) 23381 (SMG5) 9887 (SMG7) 23293 (S... |
... CFIIm CstF RNA polymerase II Ribosome binding Export CBC RNA degradation EJC m7G EJC 60S Stop codon... |
|
hsa05166
|
Human T-cell leukemia virus 1 infection |
...AM/TSP). Expression of Tax, a viral regulatory protein is critical to the pathogenesis. Tax is a tra... |
C00076 (Calcium cation) C00238 (Potassium cation) C00027 (Hydrogen peroxide) C00076 (Calcium cation)... |
...organizing center (MTOC) relocation Gag HTLV-I proteins Structural proteins Non-structural proteins ... |
|
hsa05168
|
Herpes simplex virus 1 infection |
...34.5, ICP0, ICP27, Us11 and Vhs (UL41) are the proteins involved in viral interference. |
C20640 (Cyclic GMP-AMP) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C20935 (2-5A) 4049 (LTA) 8... |
...athway ICP27 PKR eIF2α ICP34.5 PP1 dsRNA Viral protein synthesis 2'-5' OAS RNaseL US11 Aly/REF NXF1 ... |
|
hsa04936
|
Alcoholic liver disease |
...h are responsible for fatty acid oxidation and export via ACC and CPT-1. The blockade of AMPK also l... |
C00003 (NAD+) C00076 (Calcium cation) C00024 (Acetyl-CoA) C00083 (Malonyl-CoA) C00040 (Acyl-CoA) C00... |
...ignaling pathway DNA damage Lipid peroxidation Protein adducts Hepatocyte death C5a C5b C3b C3a C5AR... |
|
hsa05014
|
Amyotrophic lateral sclerosis |
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by a progressive d... |
C00025 (L-Glutamate) C00533 (Nitric oxide) C00076 (Calcium cation) C00533 (Nitric oxide) C00062 (L-A... |
...mitochondrial membrane potential Mitochondrial protein import Aggregates Bid tBid Activation Activat... |
|
hsa03250
|
Viral life cycle - HIV-1 |
|
11168 (PSIP1) 7251 (TSG101) 128866 (CHMP4B), 29082 (CHMP4A), 79643 (CHMP6) 10015 (PDCD6IP) 1234 (CCR... |
... AAA vpu tat genomic RNA splicing regulatory proteins nef rev tat Golgi body nuclear export gp41 ... |