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map00980
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Metabolism of xenobiotics by cytochrome P450 |
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...028 R07028 R07029 R07029 R07030 R07030 K07408 (CYP1A1), K07409 (CYP1A2), 1.14.14.1, R07022, R07021 K... |
...-dialdehyde protein adducts DNA adducts CYP1A2 CYP1A1 CYP1A1 CYP1A1 B[a]P-7,8-dihydrodiol-9,10-oxide... |
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map05204
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Chemical carcinogenesis - DNA adducts |
It has been estimated that exposure to environmental chemical carcinogens may contribute significant... |
... ion) K07409 (CYP1A2), K17689 (CYP3A4) K07408 (CYP1A1), K07410 (CYP1B1) K07408 (CYP1A1), K07410 (CYP... |
...olon cancer Lung cancer Breast cancer Azo dyes CYP1A1 CYP1A1 CYP1A1 Sudan I Benzenediazonium ion Nap... |
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map00830
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Retinol metabolism |
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...A7), K07424 (CYP3A), 1.14.14.1, R08392 K07408 (CYP1A1), K07409 (CYP1A2), 1.14.14.1, R08392 K07437 (C... |
...8-Hydroxy-retinoic acid CYP26 CYP2 CYP3A CYP3A CYP1A1 CYP4A11 CYP2 CYP1A CYP3A CYP2 CYP2 DHRS4 1.2.3... |
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map00140
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Steroid hormone biosynthesis |
Steroid hormones derived from cholesterol are a class of biologically active compounds in vertebrate... |
..., R03405 K01131 (STS), 3.1.6.2, R03404 K07408 (CYP1A1), K07409 (CYP1A2), K07412 (CYP2B), K07413 (CYP... |
1.1.1.62 STEROID HORMONE BIOSYNTHESIS 17α-Hydroxy-pregnenolone 21-Hydroxy-pregnenolone 11β,17α,21-T... |
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map01100
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Metabolic pathways |
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...6A), K12664 (CYP26B), K12665 (CYP26C), K07408 (CYP1A1), K07409 (CYP1A2), K17683 (CYP2A6), K07411 (CY... |
Monoterpenoid biosynthesis One carbon pool by folate Flavonoid biosynthesis Starch and sucrose metab... |
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map05208
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Chemical carcinogenesis - reactive oxygen species |
It is well established that cancer is a multi-step process which involves initiation, promotion and ... |
...AKR1C4) K10456 (KLHL19) K05696 (PTPN1) K07408 (CYP1A1) K07410 (CYP1B1) K07409 (CYP1A2) K07755 (AS3MT... |
...-3,4-semiquinone E2-2,3-quinone E2-3,4-quinone CYP1A1 CYP1B1 Pentachlorophenol Tetrachlorohydroquino... |
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map05207
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Chemical carcinogenesis - receptor activation |
Carcinogenesis is a multistage process that consists of initiation, promotion, and progression stage... |
...9093 (AHR) K17767 (AIP) K08541 (NR1I3) K07408 (CYP1A1) K01253 (EPHX1), K08726 (EPHX2), K22368 (EPHX3... |
... PCB TCDD B[α]P Estrogen signaling pathway CAR CYP1A1 EPHX GST UDPgT CYP2Bs CYP3As Xenobiotic metabo... |
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map04913
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Ovarian steroidogenesis |
The ovarian steroids, 17-beta estradiol (E2) and progesterone (P4), are critical for normal uterine ... |
...YP19A) K07434 (CYP19A) K07410 (CYP1B1) K07408 (CYP1A1) K00044 (HSD17B1), K13373 (HSD17B7) K00044 (HS... |
... 2-OH-estradiol 17β-HSD CYP19A1 CYP19A1 CYP1B1 CYP1A1 17β-HSD cAMP cAMP 17β-HSD PKA DNA DNA ARTISt I... |
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map00380
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Tryptophan metabolism |
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...00677 K00463 (IDO), 1.13.11.52, R03628 K07408 (CYP1A1), K07409 (CYP1A2), K07410 (CYP1B1), K14338 (cy... |
1.11.1.6 1.1.1.35 1.13.11.52 4.1.1.74 Nicotinamide metabolism 2.6.1.27 1.4.3.2 1.13.11.52 1.14.14.1 ... |
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map05417
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Lipid and atherosclerosis |
Atherosclerosis is a chronic inflammatory disease marked by a narrowing of the arteries from lipid-r... |
...OLR1) K03160 (TNFRSF5) K03161 (TNFSF5) K07408 (CYP1A1), K17683 (CYP2A6), K17709 (CYP2B6), K17718 (CY... |
PIP AKT PDK1 PI3K p53 signaling pathway LIPID AND ATHEROSCLEROSIS GSK3β p53 Apoptosis Apoptosis Fa... |