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Name |
Description |
Object |
Legend |
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map01522
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Endocrine resistance |
Endocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast canc... |
...59 (Tamoxifen (INN)) C16547 (Endoxifen) K08550 (ESR1), K08551 (ESR2) K08550 (ESR1), K08551 (ESR2) K0... |
ENDOCRINE RESISTANCE GPR30 Src MMP HB-EGF EGFR HB-EGF CoA DNA DNA cAMP PKA Ras Raf MEK ERK1/2 GPR30... |
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map05207
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Chemical carcinogenesis - receptor activation |
Carcinogenesis is a multistage process that consists of initiation, promotion, and progression stage... |
... C11150 (Trichloroacetate) C04623 (DDT) K08550 (ESR1), K08551 (ESR2) K08550 (ESR1), K08551 (ESR2) K0... |
CHEMICAL CARCINOGENESIS - RECEPTOR ACTIVATION EGFR DNA Ras Raf MEK ERK1/2 DNA PKA pCREB MAPK sig... |
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map05224
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Breast cancer |
Breast cancer is the leading cause of cancer death among women worldwide. The vast majority of breas... |
...osphatidylinositol-3,4,5-trisphosphate) K08550 (ESR1), K08551 (ESR2) K08550 (ESR1), K08551 (ESR2) K0... |
BREAST CANCER EGFR CoR Ras Raf MEK ERK1/2 Shc Grb2 SOS Estrogen signaling pathway Jagged Notch mTOR... |
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map04915
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Estrogen signaling pathway |
Estrogens are steroid hormones that regulate a plethora of physiological processes in mammals, inclu... |
...inobutanoate) C00951 (Estradiol-17beta) K08550 (ESR1), K08551 (ESR2) K08550 (ESR1), K08551 (ESR2) K0... |
ESTROGEN SIGNALING PATHWAY GPER c-Src MMP HB-EGF EGFR HB-EGF DNA DNA cAMP PKA Ras Raf MEK ERK1/2 p... |
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map04917
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Prolactin signaling pathway |
Prolactin (PRL) is a polypeptide hormone known to be involved in a wide range of biological function... |
...K12407 (GCK) K00501 (TH) K04248 (LHCGR) K08550 (ESR1), K08551 (ESR2) K04248 (LHCGR) K08522 (CGA), K0... |
Jak_STAT signaling pathway MAPK signaling pathway PIP Akt/PKB PI3K PROLACTIN SIGNALING PATHWAY ERK... |
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map05200
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Pathways in cancer |
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...3511 (POLK) K11126 (TERT) K22183 (TERC) K08550 (ESR1), K08551 (ESR2) K09101 (NCOA1), K11256 (NCOA3) ... |
PATHWAYS IN CANCER DCC CASP3 CASP9 CASP3 ECAD β-catenin Wnt α-catenin β-catenin ITGB Dvl ECM ITGA ... |
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map04919
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Thyroid hormone signaling pathway |
The thyroid hormones (THs) are important regulators of growth, development and metabolism. The actio... |
...K04345 (PKA) K04371 (ERK) K04451 (TP53) K08550 (ESR1) K17903 (RCAN2) K08268 (HIF1A) K07299 (SLC2A1) ... |
MAPK signaling pathway ITGB ITGA PIP Akt/PKB PDK1 PI3K PKC THYROID HORMONE SIGNALING PATHWAY Regu... |
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map04961
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Endocrine and other factor-regulated calcium reabsorption |
Calcium (Ca2+) is essential for numerous physiological functions including intracellular signalling ... |
...34 (GNAQ) K05858 (PLCB) K01325 (KLK1_2) K08550 (ESR1) K04345 (PKA) K08046 (ADCY6), K08049 (ADCY9) K0... |
Blood DNA Urinary lumen Nucleus Distal convoluted tubular (DCT) cell Tight junction Tight junction ... |
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map05205
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Proteoglycans in cancer |
Many proteoglycans (PGs) in the tumor microenvironment have been shown to be key macromolecules that... |
...848 (IQGAP1) K04371 (ERK) K04375 (ELK1) K08550 (ESR1) K06256 (CD44) K02833 (HRAS), K07827 (KRAS), K0... |
CD44v3 Tiam1 HER2 RhoA ROCK Ankyrin Cytoskeleton activation PI3K AKT CD44 Lipid Raft IP3R CAMKII Fil... |