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ENTRY	nt06022
Name	Bile acid biosynthesis
Category	Pathway view; Lipid/glycolipid metabolism
Pathway	hsa00120 Primary bile acid biosynthesis
Module	hsa_M00104 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
Disease	H00628 Congenital bile acid synthesis defect (CBAS)
Display	drug-target relation   disease type

N00805    Cholesterol − (CYP7A1,CYP7B1,CYP.. ⇉ HSD3B7 ⇉ CYP8B1 ⇉ AKR1D1 ⇉ AKR1C4 ⇉ CYP27A1 ⇉ SLC27A5 ⇉ AMACR ⇉ ACOX2 ⇉ HSD17B4 ⇉ SCP2 ⇉ ACOT8 → Cholate     CBAS3     CYP7B1*     CBAS1         HSD3B7*     CBAS2                 AKR1D1*     CTX                         CYP27A1*     CBAS4                                 AMACR*     CBAS6                                     ACOX2*

		Disease name	Disease category
CBAS3	H00628	Congenital bile acid synthesis defect	Inherited metabolic disorder
CBAS1	H00628	Congenital bile acid synthesis defect	Inherited metabolic disorder
CBAS2	H00628	Congenital bile acid synthesis defect	Inherited metabolic disorder
CTX	H00151	Cerebrotendinous xanthomatosis	Inherited metabolic disorder
CBAS4	H00628	Congenital bile acid synthesis defect	Inherited metabolic disorder
CBAS6	H00628	Congenital bile acid synthesis defect	Inherited metabolic disorder