Entry |
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Symbol |
EXT1
|
Name |
|
Pathway |
map00534 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
|
Module |
M00059 | Glycosaminoglycan biosynthesis, heparan sulfate backbone |
|
Reaction |
|
Disease |
H00493 | Heparan sulfate proteoglycan gene defects |
H00977 | Trichorhinophalangeal syndrome |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
K02366 EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases
K02366 EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
Enzymes [BR:ko01000]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.224 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
K02366 EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
2.4.1.225 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
K02366 EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
Glycosyltransferases [BR:ko01003]
Glycan extension
O-Glycan
K02366 EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Bellaiche Y, The I, Perrimon N |
Title |
Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. |
Journal |
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Sequence |
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LinkDB |
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