KEGG ORTHOLOGY: K25704

ORTHOLOGY: K25704

Entry

K25704                      KO

Symbol

ZSWIM6

Name

zinc finger SWIM domain-containing protein 6

Disease

H02210

Acromelic frontonasal dysostosis

H02397

Neurodevelopmental disorder with movement abnormalities or hypotonia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K25704  ZSWIM6; zinc finger SWIM domain-containing protein 6
Cilium and associated proteins [BR:ko03037]
Other cilia and associated proteins
  Stereociliary proteins
   K25704  ZSWIM6; zinc finger SWIM domain-containing protein 6

Genes

HSA:	57688(ZSWIM6)

PTR:	461854(ZSWIM6)

PPS:	100973835(ZSWIM6)

GGO:	101152986(ZSWIM6)

PON:	100432494(ZSWIM6)

NLE:	100581163(ZSWIM6)

HMH:	116462712(ZSWIM6)

MCC:	694793(ZSWIM6)

MCF:	102120406(ZSWIM6)

MTHB:

126956636

MNI:	105499451(ZSWIM6)

CSAB:

103222074(ZSWIM6)

CATY:

105572008(ZSWIM6)

PANU:

101016666(ZSWIM6)

TGE:	112626671(ZSWIM6)

MLEU:

105548231(ZSWIM6)

RRO:	104681646(ZSWIM6)

RBB:	108515472(ZSWIM6)

TFN:	117065173(ZSWIM6)

PTEH:

111541602(ZSWIM6)

CANG:

105519043(ZSWIM6)

CJC:	100391293(ZSWIM6)

SBQ:	101031229(ZSWIM6)

CIMI:

108283065(ZSWIM6)

CSYR:

103275821(ZSWIM6)

MMUR:

105877258(ZSWIM6)

LCAT:

123648636(ZSWIM6)

PCOQ:

105826532(ZSWIM6)

OGA:	100942553(ZSWIM6)

MMU:	67263(Zswim6)

MCAL:

110308414(Zswim6)

MPAH:

110328937(Zswim6)

RNO:	310062(Zswim6)

MCOC:

116083174(Zswim6)

ANU:	117723956(Zswim6)

MUN:	110546131(Zswim6)

CGE:	100757838(Zswim6)

MAUA:

101826754(Zswim6)

PROB:

127220998(Zswim6)

PLEU:

114703410(Zswim6)

MORG:

121455925(Zswim6)

MFOT:

126512611

AAMP:

119810531(Zswim6)

NGI:	103752526(Zswim6)

HGL:	101704420(Zswim6)

CPOC:

100722775(Zswim6)

CCAN:

109686948

DORD:

105992437(Zswim6)

DSP:	122117230(Zswim6)

PLOP:

125367705(Zswim6)

NCAR:

124986789

MMMA:

107151861(Zswim6)

OCU:

100353781

OPI:	101530361(ZSWIM6)

TUP:	102476181(ZSWIM6)

GVR:	103593183(ZSWIM6)

CFA:	478068(ZSWIM6)

CLUD:

112660584(ZSWIM6)

VVP:	112908123(ZSWIM6)

VLG:	121496640(ZSWIM6)

NPO:	129514043(ZSWIM6)

AML:	100473772(ZSWIM6)

UMR:	103663883(ZSWIM6)

UAH:	113254899(ZSWIM6)

UAR:	123790163(ZSWIM6)

ELK:

111156906

LLV:

125101039

MPUF:

101669889(ZSWIM6)

MNP:	132028670(ZSWIM6)

MLK:	131832272(ZSWIM6)

NVS:	122889155(ZSWIM6)

ORO:	101384214(ZSWIM6)

EJU:	114224681(ZSWIM6)

ZCA:	113928780(ZSWIM6)

MLX:	118016822(ZSWIM6)

NSU:	110591255(ZSWIM6)

LWW:

102741116

FCA:	101100860(ZSWIM6)

PYU:	121042014(ZSWIM6)

PCOO:

112860592(ZSWIM6)

PBG:	122489334(ZSWIM6)

PVIV:

125165472(ZSWIM6)

LRUF:

124517573

PTG:	102969153(ZSWIM6)

PPAD:

109246374(ZSWIM6)

PUC:

125935663

AJU:

106976369

HHV:	120247594(ZSWIM6)

BTA:	538841(ZSWIM6)

BOM:	102287825(ZSWIM6)

BIU:	109574922(ZSWIM6)

BBUB:

102403849(ZSWIM6)

BBIS:

104992611(ZSWIM6)

CHX:	102180968(ZSWIM6)

OAS:	101112003(ZSWIM6)

BTAX:

128066129(ZSWIM6)

ODA:	120879396(ZSWIM6)

CCAD:

122454412(ZSWIM6)

MBEZ:

129553232(ZSWIM6)

SSC:	100620165(ZSWIM6)

CFR:	102507042(ZSWIM6)

CBAI:

105077780(ZSWIM6)

CDK:	105084733(ZSWIM6)

VPC:	102540325(ZSWIM6)

BACU:

102998874(ZSWIM6)

BMUS:

118893052(ZSWIM6)

LVE:	103072732(ZSWIM6)

OOR:	101273876(ZSWIM6)

DLE:	111186358(ZSWIM6)

PCAD:

102977177(ZSWIM6)

PSIU:

116750553(ZSWIM6)

NASI:

112413406(ZSWIM6)

ECB:	100060125(ZSWIM6)

EPZ:	103552013(ZSWIM6)

EAI:	106846773(ZSWIM6)

MYB:	102242303(ZSWIM6)

MYD:	102757329(ZSWIM6)

MMYO:

118656249(ZSWIM6)

MLF:	102426536(ZSWIM6)

PKL:	118702634(ZSWIM6)

EFUS:

103305318(ZSWIM6)

MNA:	107526337(ZSWIM6)

DRO:	112320931(ZSWIM6)

SHON:

118998619(ZSWIM6)

AJM:	119057183(ZSWIM6)

PDIC:

114491714(ZSWIM6)

PHAS:

123824801(ZSWIM6)

MMF:	118641617(ZSWIM6)

PPAM:

129074568(ZSWIM6)

HAI:	109392877(ZSWIM6)

RFQ:	117024985(ZSWIM6)

PALE:

102882278(ZSWIM6)

PGIG:

120608214(ZSWIM6)

PVP:	105303629(ZSWIM6)

RAY:	107506368(ZSWIM6)

MJV:	108409778(ZSWIM6)

TOD:	119260548(ZSWIM6)

SARA:

101555727(ZSWIM6)

SETR:

126001474(ZSWIM6)

TMU:

101343167

ETF:	101643286(ZSWIM6)

DNM:

101445165

MDO:	100619753(ZSWIM6)

GAS:	123251709(ZSWIM6)

SHR:	100918344(ZSWIM6)

AFZ:

127557787

PCW:	110222311(ZSWIM6)

OAA:	100076080(ZSWIM6)

GGA:	100859602 770670(ZSWIM6)

PCOC:

116236674(ZSWIM6)

CJO:	107306017(ZSWIM6)

TPAI:

128074504(ZSWIM6)

LMUT:

125686398 125686536(ZSWIM6)

NMEL:

110389408(ZSWIM6)

APLA:

101797738 101802677(ZSWIM6)

ACYG:

106035628(ZSWIM6)

CATA:

118251505(ZSWIM6)

AFUL:

116500812(ZSWIM6) 116501425

TGU:	100221027(ZSWIM6) 116806985

LSR:	110472568(ZSWIM6)

SCAN:

103823146(ZSWIM6) 103824691

PMOA:

120502341(ZSWIM6)

OTC:	121341265(ZSWIM6)

PRUF:

121355395(ZSWIM6)

GFR:	102035057(ZSWIM6) 102038536

FAB:	101815500(ZSWIM6)

OMA:	130265017(ZSWIM6)

PHI:	102108778(ZSWIM6)

PMAJ:

107216225(ZSWIM6)

CCAE:

111941396(ZSWIM6)

CBRC:

103611673 103624003(ZSWIM6)

ETL:	114057202(ZSWIM6)

ZAB:	102067665(ZSWIM6)

SVG:	106856468(ZSWIM6)

MMEA:

130588746(ZSWIM6)

HRT:	120764905 120765081(ZSWIM6)

FPG:	101921178(ZSWIM6)

FCH:	102058988(ZSWIM6)

CLV:	102095874(ZSWIM6)

EGZ:	104128342(ZSWIM6)

NNI:

PCRI:

PLET:

EHS:

PCAO:

ACUN:

113489674(ZSWIM6)

TALA:

104369253(ZSWIM6)

PADL:

103918751(ZSWIM6)

AFOR:

103893425(ZSWIM6)

ACHC:

115336443(ZSWIM6) 121232866

HALD:

104322283

HLE:	104839961(ZSWIM6)

AGEN:

126035241 126036050

GCL:	127027604 127028970

CSTI:

104554317(ZSWIM6)

CMAC:

104479379(ZSWIM6)

MUI:	104546008(ZSWIM6)

BREG:

104635548

FGA:

104069182

GSTE:

104254853

LDI:	104352229(ZSWIM6)

MNB:

103772318

OHA:	104337720(ZSWIM6)

NNT:	104412449(ZSWIM6)

SHAB:

115601409(ZSWIM6) 115618985

DPUB:

104302229(ZSWIM6)

PGUU:

104466547

ACAR:

104532026

CPEA:

104393907 104395677(ZSWIM6)

AVIT:

104274869(ZSWIM6)

CVF:	104295378 104295727(ZSWIM6)

RTD:	128901933 128902161(ZSWIM6)

CUCA:

104058132(ZSWIM6)

BRHI:

104501840

AROW:

112971774(ZSWIM6)

NPD:	112945487(ZSWIM6)

TGT:	104564843(ZSWIM6) 104580198

DNE:	112995750(ZSWIM6)

SCAM:

104146912(ZSWIM6)

ASN:	102387516(ZSWIM6)

AMJ:	102558165(ZSWIM6)

CPOO:

109307949(ZSWIM6)

GGN:	109297785(ZSWIM6)

PSS:	102455098(ZSWIM6)

CMY:	102947211(ZSWIM6)

CCAY:

125636719(ZSWIM6)

DCC:	119855439(ZSWIM6)

CPIC:

101943872(ZSWIM6)

TST:	117878698(ZSWIM6)

CABI:

116837037(ZSWIM6)

MRV:	120407803(ZSWIM6)

ACS:	100554088(zswim6)

ASAO:

132767013(ZSWIM6)

PVT:	110073929(ZSWIM6)

SUND:

121924042(ZSWIM6)

PBI:	103051675(ZSWIM6)

PMUR:

107289922(ZSWIM6)

CTIG:

120297353(ZSWIM6)

TSR:	106540484(ZSWIM6)

PGUT:

117679223(ZSWIM6)

APRI:

131191664(ZSWIM6)

PTEX:

113447073(ZSWIM6)

NSS:	113413915(ZSWIM6)

VKO:	123031614(ZSWIM6)

PMUA:

114606138(ZSWIM6)

PRAF:

128423217(ZSWIM6)

ZVI:	118077072(ZSWIM6)

HCG:	128343625(ZSWIM6)

GJA:	107106618(ZSWIM6)

STOW:

125436584(ZSWIM6)

EMC:	129334879(ZSWIM6)

XLA:	108695777 108704433

XTR:	100490710(zswim6)

NPR:	108788211(ZSWIM6)

RTEM:

120928752(ZSWIM6)

BBUF:

120992374(ZSWIM6)

BGAR:

122924760(ZSWIM6)

MUO:	115463011(ZSWIM6)

GSH:	117353936(ZSWIM6)

DRE:	403057(zswim6)

SRX:	107706746 107722335(zswim6)

SANH:

107654486 107704169

SGH:	107554526(zswim6) 107589000

CCAR:

109088243

CAUA:

113054719 113110195 113110205

CGIB:

127966223 128020814

PTET:

122333801(zswim6)

LROH:

127171795(zswim6)

OMC:	131548057(zswim6)

PPRM:

120482175(zswim6)

RKG:

130094897

MAMB:

125262534(zswim6)

CIDE:

127520484

MASI:

127432561 127433697

TROS:

130545844(zswim6)

TDW:	130411667(zswim6)

MANU:

129446443(zswim6)

IPU:

108277136

IFU:	128620047(zswim6)

PHYP:

113544807

SMEO:

124393318(zswim6)

TFD:	113638340(zswim6)

TVC:	132863122(zswim6)

AMEX:

103035744(zswim6)

CMAO:

118824255(zswim6)

EEE:	113583925(zswim6)

CHAR:

105891105(zswim6)

TRU:	101062012 101070471(zswim6)

TFS:	130517170(zswim6) 130526150

TNG:	GSTEN00025262G001 GSTEN00032657G001

LCO:	104922960(zswim6) 104939028

NCC:

104941846

TBEN:

117472743 117476561(zswim6)

CGOB:

115013291(zswim6) 115016708

PGEO:

117452830 117456130(zswim6)

GACU:

117558586 117561481(zswim6)

EMAC:

134868734(zswim6) 134873581

ELY:	117252723 117269780(zswim6)

EFO:	125878673(zswim6) 125891015

PLEP:

121944365 121959929

SLUC:

116051053(zswim6) 116056759

ECRA:

117944626 117959128(zswim6)

ESP:	116689595(zswim6) 116703993

PFLV:

114555950(zswim6) 114571360

GAT:	120830336 120831787(zswim6)

PPUG:

119225058 119226359(zswim6)

AFB:	129100956 129102115(zswim6)

CLUM:

117736598 117740924(zswim6)

PSWI:

130197455 130204979(zswim6)

MSAM:

119892289 119914615(zswim6)

SCHU:

122865167(zswim6) 122876831

CUD:	121509695 121524709(zswim6)

ALAT:

119019964 119029948(zswim6)

MZE:	101467654 101472410(zswim6)

ONL:	100698789 100703710(zswim6)

OAU:	116311156 116315900(zswim6)

OLA:	101165407 101165561(zswim6)

OML:	112148535 112163206(zswim6)

CSAI:

133450594 133455043(zswim6)

XMA:	102224237 102237657(zswim6)

XCO:	114149487 114154424(zswim6)

XHE:	116724226 116729637(zswim6)

PRET:

103470165(zswim6) 103473262

PFOR:

103135440 103135471 103151015

PLAI:

106956041(zswim6) 106963268

PMEI:

106916967(zswim6) 106917871 106926932

GAF:	122819738(zswim6) 122828770

PPRL:

129365827 129374218(zswim6)

CVG:	107090586 107098307(zswim6)

CTUL:

119781104 119784774(zswim6)

GMU:	124872586(zswim6) 124877636

NFU:	107374803 107394082(zswim6)

KMR:	108244811 108250365

NWH:	119413919(zswim6)

AOCE:

111565812 111588638(zswim6)

MCEP:

124996683(zswim6) 125012341

CSEM:

POV:

SSEN:

HHIP:

HSP:	118115128 118125766(zswim6)

SMAU:

118305017(zswim6) 118313421

LCF:	108878552 108895496(zswim6)

SDU:	111230842(zswim6) 111239042

SLAL:

111645180(zswim6) 111666832

XGL:	120805599 120806377(zswim6)

HCQ:	109520662(zswim6) 109529129

SSCV:

125979746 125994563

SBIA:

133490754(zswim6) 133499934

PEE:	133399901 133413318(zswim6)

PTAO:

133475255 133490343(zswim6)

BPEC:

110157429 110167067(zswim6)

MALB:

109951190 109956622(zswim6)

BSPL:

114861925 114867077(zswim6)

SJO:	128364775 128379872(zswim6)

SASA:

106562383 106568302 106585158(zswim6)

STRU:

115149308 115159244 115164232(zswim6) 115200409

OTW:	112219636(zswim6) 112248775 112257465

OMY:	110523854 110525926 110536801

OGO:	123999179(zswim6) 124034118 124048650

ONE:	115111829 115117191

OKI:	109867986 109882706 109892432 109894937

OKE:	118358514 118377313 118387828 118393445

SALP:

111974077 112071385

SNH:	120025755(zswim6) 120044377 120045045

CCLU:

121574143 121582774 121583081 121585079

ELS:	105014114(zswim6) 105014808

SFM:	108938585(zswim6)

PKI:	111839224(zswim6)

AANG:

118206533 118212811(zswim6)

LOC:	102690923(zswim6)

PSPA:

121300767 121316863

ARUT:

117400039 117403685

PSEX:

120532585(zswim6)

LCM:	102352822(ZSWIM6)

CMK:

RTP:

CPLA:

HOC:

LERI:

Reference

PMID:25105228

Authors

Smith JD, Hing AV, Clarke CM, Johnson NM, Perez FA, Park SS, Horst JA, Mecham B, Maves L, Nickerson DA, Cunningham ML

Title

Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis.

Journal

Am J Hum Genet 95:235-40 (2014)
DOI:10.1016/j.ajhg.2014.07.008

Sequence

[hsa:57688]

LinkDB

DBGET integrated database retrieval system