KEGG   PATHWAY: acyg00230
Entry
acyg00230                   Pathway                                
Name
Purine metabolism - Anser cygnoides domesticus (swan goose)
Class
Metabolism; Nucleotide metabolism
Pathway map
acyg00230  Purine metabolism
acyg00230

Module
acyg_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:acyg00230]
acyg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:acyg00230]
acyg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:acyg00230]
acyg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:acyg00230]
acyg_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:acyg00230]
acyg_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:acyg00230]
Other DBs
GO: 0006163 0042278
Organism
Anser cygnoides domesticus (swan goose) [GN:acyg]
Gene
106041864  NUDT9; ADP-ribose pyrophosphatase, mitochondrial isoform X1 [KO:K13988] [EC:3.6.1.13]
125184266  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
106046205  NUDT5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
106032919  PGM1; phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
106039078  PGM2; phosphoglucomutase-2 isoform X1 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
106037754  PRPS1; ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
106042541  PRPS2; ribose-phosphate pyrophosphokinase 2 isoform X3 [KO:K00948] [EC:2.7.6.1]
106030802  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
106043414  GART; trifunctional purine biosynthetic protein adenosine-3 isoform X1 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
106043431  trifunctional purine biosynthetic protein adenosine-3-like isoform X2 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
106048610  PAICS; multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
106035926  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
106034458  ATIC; bifunctional purine biosynthesis protein ATIC [KO:K00602] [EC:2.1.2.3 3.5.4.10]
106046508  APRT; adenine phosphoribosyltransferase isoform X1 [KO:K00759] [EC:2.4.2.7]
106030817  NT5C1B; cytosolic 5'-nucleotidase 1B [KO:K01081] [EC:3.1.3.5]
106042626  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
106031839  NT5C2; cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
106037881  NT5C1A; cytosolic 5'-nucleotidase 1A isoform X1 [KO:K01081] [EC:3.1.3.5]
106032183  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
106049713  cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
106035383  NT5E; 5'-nucleotidase isoform X1 [KO:K19970] [EC:3.1.3.5]
106033124  LOW QUALITY PROTEIN: purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
106035090  LACC1; purine nucleoside phosphorylase LACC1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
106033262  hypoxanthine-guanine phosphoribosyltransferase-like isoform X1 [KO:K00760] [EC:2.4.2.8]
106037444  HPRT1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
106035431  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 isoform X1 [KO:K00088] [EC:1.1.1.205]
106033572  NME3; nucleoside diphosphate kinase 3 isoform X1 [KO:K00940] [EC:2.7.4.6]
106038233  NME7; nucleoside diphosphate kinase 7 isoform X1 [KO:K00940] [EC:2.7.4.6]
106034732  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
106034733  nucleoside diphosphate kinase-like [KO:K00940] [EC:2.7.4.6]
106048162  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
125182346  NME4; nucleoside diphosphate kinase, mitochondrial [KO:K00940] [EC:2.7.4.6]
106032595  AK9; adenylate kinase 9 isoform X3 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
106037034  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
106046665  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 isoform X1 [KO:K01510] [EC:3.6.1.5]
106037126  ectonucleoside triphosphate diphosphohydrolase 8 isoform X1 [KO:K01510] [EC:3.6.1.5]
106037128  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
106037395  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
106046784  CANT1; soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
106049706  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
106038827  ENTPD5; nucleoside diphosphate phosphatase ENTPD5 [KO:K01511] [EC:3.6.1.6]
106044765  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
106041552  ITPA; inosine triphosphate pyrophosphatase isoform X1 [KO:K01519] [EC:3.6.1.66]
106031596  XDH; xanthine dehydrogenase/oxidase isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
106045165  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
125181766  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]-like isoform X1 [KO:K01518] [EC:3.6.1.17]
106043513  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
106041705  GMPR; GMP reductase 1 [KO:K00364] [EC:1.7.1.7]
106044473  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
106036856  GUK1; guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
106048561  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
106035272  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
106030813  RRM2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
106032410  HDDC2; 5'-deoxynucleotidase HDDC2 isoform X1 [KO:K07023] [EC:3.1.3.89]
106047633  DGUOK; deoxyguanosine kinase, mitochondrial [KO:K00904] [EC:2.7.1.113]
106032673  deoxycytidine kinase 2 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
106043942  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
106049267  PRUNE1; exopolyphosphatase PRUNE1 isoform X1 [KO:K01514] [EC:3.6.1.11]
106046455  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
106036531  ADCY2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
106038094  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
106029894  ADCY5; adenylate cyclase type 5 isoform X1 [KO:K08045] [EC:4.6.1.1]
106039584  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
106046364  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
106033354  ADCY9; adenylate cyclase type 9 isoform X2 [KO:K08049] [EC:4.6.1.1]
125181573  ADCY10; adenylate cyclase type 10 isoform X1 [KO:K11265] [EC:4.6.1.1]
106032273  GUCY1A1; guanylate cyclase soluble subunit alpha-1 isoform X1 [KO:K12318] [EC:4.6.1.2]
106047549  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
106032278  GUCY1B1; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
106036260  guanylate cyclase soluble subunit beta-2-like isoform X1 [KO:K12319] [EC:4.6.1.2]
106046052  GUCY2C; guanylyl cyclase C [KO:K12320] [EC:4.6.1.2]
106029423  retinal guanylyl cyclase 1-like [KO:K12321] [EC:4.6.1.2]
106042382  GUCY2F; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
106049109  NPR1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
106036311  NPR2; atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
106043048  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12324] [EC:4.6.1.2]
106030054  PDE1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X3 [KO:K13755] [EC:3.1.4.17]
106045499  PDE1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X15 [KO:K13755] [EC:3.1.4.17]
106030879  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
106040925  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1 [KO:K13296] [EC:3.1.4.17]
106038653  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X6 [KO:K13762] [EC:3.1.4.35]
106040414  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
106042483  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
106044804  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
106049409  PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13759]
106045732  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
106036126  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X2 [KO:K13761] [EC:3.1.4.35]
106039510  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
106030031  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X3 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
106049555  ADSS2; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
106037182  ADSS1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
106040890  AMPD3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
106049764  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
106041321  AMPD1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
106033065  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
106040574  ADA; adenosine deaminase isoform X1 [KO:K01488] [EC:3.5.4.4]
106030929  ADA2; adenosine deaminase 2 [KO:K19572] [EC:3.5.4.4]
106043622  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
106034021  AK5; adenylate kinase isoenzyme 5 isoform X1 [KO:K00939] [EC:2.7.4.3]
106038035  AK2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
106036231  AK7; adenylate kinase 7 isoform X1 [KO:K00939] [EC:2.7.4.3]
106044101  AK8; adenylate kinase 8 isoform X3 [KO:K00939] [EC:2.7.4.3]
106047279  AK1; adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
106042724  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
106046388  AK3; GTP:AMP phosphotransferase AK3, mitochondrial isoform X1 [KO:K00944] [EC:2.7.4.10]
106037087  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
106048051  NTPCR; cancer-related nucleoside-triphosphatase isoform X1 [KO:K06928] [EC:3.6.1.15]
106032498  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
106032499  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
106029621  PDE4C; LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
106043574  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
106035620  cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [KO:K13293] [EC:3.1.4.53]
106032509  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X2 [KO:K18436] [EC:3.1.4.53]
106039047  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X2 [KO:K18436] [EC:3.1.4.53]
106042118  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [KO:K18437] [EC:3.1.4.53]
106043357  PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1 [KO:K18437] [EC:3.1.4.53]
106035488  FHIT; bis(5'-adenosyl)-triphosphatase isoform X5 [KO:K01522] [EC:3.6.1.29]
106038201  ENPP4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
106030864  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
106038652  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
106033995  uricase-like [KO:K00365] [EC:1.7.3.3]
106046591  cadherin-1-like [KO:K07127] [EC:3.5.2.17]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
acyg00030  Pentose phosphate pathway
acyg00220  Arginine biosynthesis
acyg00250  Alanine, aspartate and glutamate metabolism
acyg00260  Glycine, serine and threonine metabolism
acyg00340  Histidine metabolism
acyg00630  Glyoxylate and dicarboxylate metabolism
acyg00730  Thiamine metabolism
acyg00740  Riboflavin metabolism
acyg00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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