KEGG   PATHWAY: aml03082
Entry
aml03082                    Pathway                                
Name
ATP-dependent chromatin remodeling - Ailuropoda melanoleuca (giant panda)
Class
Genetic Information Processing; Chromosome
Pathway map
aml03082  ATP-dependent chromatin remodeling
aml03082

Organism
Ailuropoda melanoleuca (giant panda) [GN:aml]
Gene
100471951  SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [KO:K11654] [EC:5.6.2.-]
100468679  BAZ1A; bromodomain adjacent to zinc finger domain protein 1A [KO:K11655]
100470024  BAZ1B; tyrosine-protein kinase BAZ1B [KO:K11658]
100473683  BAZ2A; bromodomain adjacent to zinc finger domain protein 2A isoform X1 [KO:K15224]
100479108  BAZ2B; bromodomain adjacent to zinc finger domain protein 2B isoform X1 [KO:K26167]
100463991  CHRAC1; chromatin accessibility complex protein 1 isoform X1 [KO:K11656]
100475622  POLE3; DNA polymerase epsilon subunit 3 [KO:K02326] [EC:2.7.7.7]
100468567  RSF1; remodeling and spacing factor 1 isoform X3 [KO:K11657]
100474030  SMARCA1; probable global transcription activator SNF2L1 isoform X1 [KO:K11727] [EC:5.6.2.-]
100482950  BPTF; LOW QUALITY PROTEIN: nucleosome-remodeling factor subunit BPTF [KO:K11728]
100476148  RBBP4; histone-binding protein RBBP4 [KO:K10752]
100470014  RBBP7; histone-binding protein RBBP7 isoform X3 [KO:K11659]
100471286  C17H17orf49; chromatin complexes subunit BAP18 isoform X1 [KO:K23406]
100466191  cat eye syndrome critical region protein 2 isoform X1 [KO:K25830]
100480350  CHD3; chromodomain-helicase-DNA-binding protein 3 [KO:K11642] [EC:5.6.2.-]
100478235  CHD4; LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 4 [KO:K11643] [EC:5.6.2.-]
100477725  HDAC1; histone deacetylase 1 isoform X1 [KO:K06067] [EC:3.5.1.98]
100478424  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
100466799  MBD2; methyl-CpG-binding domain protein 2 [KO:K11590]
100467002  MBD3; methyl-CpG-binding domain protein 3 isoform X3 [KO:K11591]
100467866  MTA2; metastasis-associated protein MTA2 isoform X2 [KO:K11660]
100479014  MTA3; metastasis-associated protein MTA3 [KO:K11660]
100464283  metastasis-associated protein MTA1 [KO:K11660]
100463834  GATAD2B; transcriptional repressor p66-beta [KO:K23194]
100482809  GATAD2A; transcriptional repressor p66-alpha isoform X3 [KO:K23194]
100480166  PHF6; PHD finger protein 6 isoform X2 [KO:K23310]
100482058  CDK2AP1; cyclin-dependent kinase 2-associated protein 1 [KO:K26454]
100466001  CDK2AP2; cyclin-dependent kinase 2-associated protein 2 isoform X1 [KO:K26455]
100464834  SMARCA4; transcription activator BRG1 isoform X3 [KO:K11647] [EC:5.6.2.-]
100471512  SMARCA2; probable global transcription activator SNF2L2 [KO:K11647] [EC:5.6.2.-]
100484496  SMARCC2; SWI/SNF complex subunit SMARCC2 [KO:K11649]
100467135  SMARCC1; SWI/SNF complex subunit SMARCC1 [KO:K11649]
100466469  SMARCD3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X3 [KO:K11650]
100469350  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [KO:K11650]
100475495  SMARCD2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 [KO:K11650]
100470126  SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1 [KO:K11651]
100466132  ACTG1; actin, cytoplasmic 2 [KO:K05692]
100481739  actin [KO:K05692]
117800125  actin, cytoplasmic 1 [KO:K05692]
117800181  actin, cytoplasmic type 5 isoform X1 [KO:K05692]
117800361  actin, cytoplasmic 1-like [KO:K05692]
117800408  actin, cytoplasmic 1 [KO:K05692]
100480297  ACTL6A; actin-like protein 6A [KO:K11340]
100484805  ACTL6B; actin-like protein 6B isoform X1 [KO:K11652]
100483452  BCL7C; B-cell CLL/lymphoma 7 protein family member C [KO:K25605]
100470277  BCL7B; B-cell CLL/lymphoma 7 protein family member B [KO:K25605]
100479045  BCL7A; B-cell CLL/lymphoma 7 protein family member A [KO:K25605]
100480722  SS18; protein SSXT isoform X3 [KO:K15623]
100472933  SS18L1; calcium-responsive transactivator isoform X3 [KO:K15623]
100477694  ARID1A; AT-rich interactive domain-containing protein 1A isoform X1 [KO:K11653]
100464304  ARID1B; AT-rich interactive domain-containing protein 1B isoform X1 [KO:K11653]
100469121  DPF1; zinc finger protein neuro-d4 isoform X5 [KO:K22198]
100479090  DPF3; zinc finger protein DPF3 isoform X1 [KO:K22198]
100467907  DPF2; LOW QUALITY PROTEIN: zinc finger protein ubi-d4 [KO:K13196]
100468277  ARID2; AT-rich interactive domain-containing protein 2 [KO:K11765]
100483929  PBRM1; protein polybromo-1 isoform X13 [KO:K11757]
100468978  BRD7; bromodomain-containing protein 7 [KO:K11723]
100483957  PHF10; PHD finger protein 10 isoform X1 [KO:K22197]
100484550  BRD9; bromodomain-containing protein 9 [KO:K22184]
100473282  BICRA; BRD4-interacting chromatin-remodeling complex-associated protein [KO:K25612]
100477955  BICRAL; BRD4-interacting chromatin-remodeling complex-associated protein-like [KO:K25613]
100481972  INO80; chromatin-remodeling ATPase INO80 isoform X1 [KO:K11665] [EC:5.6.2.-]
100473954  INO80B; INO80 complex subunit B isoform X2 [KO:K11666]
100466816  INO80C; INO80 complex subunit C isoform X1 [KO:K11667]
100484437  INO80D; INO80 complex subunit D isoform X1 [KO:K11668]
100477349  INO80E; INO80 complex subunit E isoform X4 [KO:K11669]
100463772  TFPT; TCF3 fusion partner isoform X1 [KO:K11670]
100467640  NFRKB; nuclear factor related to kappa-B-binding protein isoform X1 [KO:K11671]
100471618  MCRS1; microspherule protein 1 isoform X2 [KO:K11674]
100484953  UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X3 [KO:K05610] [EC:3.4.19.12]
100478901  RUVBL1; LOW QUALITY PROTEIN: ruvB-like 1 [KO:K04499] [EC:5.6.2.4]
100475956  RUVBL2; ruvB-like 2 [KO:K11338] [EC:5.6.2.3]
100476539  ACTR5; actin-related protein 5 [KO:K11672]
100467196  ACTR8; actin-related protein 8 [KO:K11673]
100474192  YY1; transcriptional repressor protein YY1 [KO:K09201]
100479005  SRCAP; helicase SRCAP isoform X1 [KO:K11661] [EC:5.6.2.-]
100473654  DMAP1; DNA methyltransferase 1-associated protein 1 isoform X1 [KO:K11324]
100482765  YEATS4; YEATS domain-containing protein 4 isoform X1 [KO:K11341]
100478581  VPS72; vacuolar protein sorting-associated protein 72 homolog [KO:K11664]
100466888  core histone macro-H2A.1 isoform X2 [KO:K11251]
100479700  histone H2A.J [KO:K11251]
100480781  histone H2A type 1-D [KO:K11251]
100464863  histone H2A type 1-E [KO:K11251]
100463612  histone H2AX [KO:K11251]
100465190  histone H2A type 1 [KO:K11251]
100467516  histone H2A-Bbd type 1 [KO:K11251]
100478013  histone H2A.Z [KO:K11251]
100482551  histone H2A type 3 [KO:K11251]
100463617  histone H2A-Bbd type 2/3 [KO:K11251]
100465958  histone H2A type 2-B [KO:K11251]
100466373  histone H2A type 2-C [KO:K11251]
100482816  core histone macro-H2A.2 [KO:K11251]
100479502  histone H2A.V isoform X1 [KO:K11251]
100484819  histone H2A-Bbd type 2/3 [KO:K11251]
100477187  histone H2A-Bbd type 2/3 [KO:K11251]
100483293  histone H2A type 1-E [KO:K11251]
100467187  histone H2A type 1-E [KO:K11251]
100466194  LOW QUALITY PROTEIN: histone H2A type 1 [KO:K11251]
100482073  histone H2A type 1-H [KO:K11251]
109490384  histone H2A-Bbd type 1 [KO:K11251]
105238125  histone H2A-like [KO:K11251]
100482328  LOW QUALITY PROTEIN: histone H2A type 1-A [KO:K11251]
105241088  histone H2A type 1-E [KO:K11251]
100465694  LOW QUALITY PROTEIN: histone H2A type 1-H [KO:K11251]
100466688  LOW QUALITY PROTEIN: histone H2A type 1-H [KO:K11251]
100468629  LOW QUALITY PROTEIN: histone H2A type 1-E [KO:K11251]
117794999  histone H2A type 1-E [KO:K11251]
117804403  histone H2A.Z [KO:K11251]
100483791  histone H2A type 1-H [KO:K11251]
100469634  ACTR6; actin-related protein 6 isoform X1 [KO:K11662]
100468205  ZNHIT1; zinc finger HIT domain-containing protein 1 [KO:K11663]
100469764  EP400; LOW QUALITY PROTEIN: E1A-binding protein p400 [KO:K11320] [EC:5.6.2.-]
100484031  TRRAP; transformation/transcription domain-associated protein isoform X1 [KO:K08874]
100481264  MORF4L1; mortality factor 4-like protein 1 [KO:K11339]
100468185  MORF4L2; mortality factor 4-like protein 2 [KO:K11342]
100481523  MRGBP; MRG/MORF4L-binding protein [KO:K11343]
100464252  BRD8; bromodomain-containing protein 8 isoform X5 [KO:K11321]
100465922  ING3; inhibitor of growth protein 3 isoform X1 [KO:K11319]
100483449  EPC2; enhancer of polycomb homolog 2 isoform X1 [KO:K11322]
100473445  EPC1; enhancer of polycomb homolog 1 isoform X3 [KO:K11322]
100481268  MEAF6; chromatin modification-related protein MEAF6 isoform X2 [KO:K11344]
100465899  KAT5; histone acetyltransferase KAT5 isoform X3 [KO:K11304] [EC:2.3.1.48]
Reference
  Authors
Hasan N, Ahuja N
  Title
The Emerging Roles of ATP-Dependent Chromatin Remodeling Complexes in Pancreatic Cancer.
  Journal
Cancers (Basel) 11:cancers11121859 (2019)
DOI:10.3390/cancers11121859
Reference
  Authors
He S, Wu Z, Tian Y, Yu Z, Yu J, Wang X, Li J, Liu B, Xu Y
  Title
Structure of nucleosome-bound human BAF complex.
  Journal
Science 367:875-881 (2020)
DOI:10.1126/science.aaz9761
Reference
  Authors
Wanior M, Kramer A, Knapp S, Joerger AC
  Title
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy.
  Journal
Oncogene 40:3637-3654 (2021)
DOI:10.1038/s41388-021-01781-x
Reference
  Authors
Burgio G, Onorati MC, Corona DF
  Title
Chromatin remodeling regulation by small molecules and metabolites.
  Journal
Biochim Biophys Acta 1799:671-80 (2010)
DOI:10.1016/j.bbagrm.2010.05.007
KO pathway
ko03082   
LinkDB

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