KEGG   PATHWAY: mthb05164
Entry
mthb05164                   Pathway                                
Name
Influenza A - Macaca thibetana thibetana (Pere David's macaque)
Description
Influenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains that cause pandemics arise from avian influenza virus by genetic reassortment among influenza viruses and two surface glycoproteins HA and NA form the basis of serologically distinct virus types. The innate immune system recognizes invaded virus through multiple mechanisms. Viral non-structural NS1 protein is a multifunctional virulence factor that interfere IFN-mediated antiviral response. It inhibits IFN production by blocking activation of transcription factors such as NF-kappa B and IRF3. NS1 further inhibits the activation of IFN-induced antiviral genes. PB1-F2 protein is another virulence factor that induce apoptosis of infected cells, which results in life-threatening bronchiolitis.
Class
Human Diseases; Infectious disease: viral
Pathway map
mthb05164  Influenza A
mthb05164

Organism
Macaca thibetana thibetana (Pere David's macaque) [GN:mthb]
Gene
126944863  tryptase beta-2-like [KO:K01340] [EC:3.4.21.59]
126944864  tryptase beta-2 isoform X1 [KO:K01340] [EC:3.4.21.59]
126953650  plasminogen [KO:K01315] [EC:3.4.21.7]
126951077  trypsin-2 isoform X1 [KO:K01312] [EC:3.4.21.4]
126951078  serine protease 1-like isoform X1 [KO:K01312] [EC:3.4.21.4]
126951080  trypsin-2-like isoform X1 [KO:K01312] [EC:3.4.21.4]
126951081  putative trypsin-6 isoform X1 [KO:K01312] [EC:3.4.21.4]
126951082  trypsin-2-like [KO:K01312] [EC:3.4.21.4]
126951123  putative trypsin-6 [KO:K01312] [EC:3.4.21.4]
126950687  transmembrane protease serine 2 isoform X1 [KO:K09633] [EC:3.4.21.122]
126936077  transmembrane protease serine 4 [KO:K09635] [EC:3.4.21.-]
126954506  transmembrane protease serine 11D [KO:K09641] [EC:3.4.21.-]
126944386  protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
126931427  2'-5'-oligoadenylate synthase 3 isoform X1 [KO:K14216] [EC:2.7.7.84]
126931448  2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
126931471  2'-5'-oligoadenylate synthase 1 isoform X1 [KO:K14216] [EC:2.7.7.84]
126940643  2-5A-dependent ribonuclease [KO:K01165]
126942438  dnaJ homolog subfamily B member 1 isoform X1 [KO:K09507]
126940586  dnaJ homolog subfamily C member 3 [KO:K09523]
126933547  interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
126958657  eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
126939380  LOW QUALITY PROTEIN: E3 ubiquitin/ISG15 ligase TRIM25 [KO:K10652] [EC:2.3.2.27]
126937384  antiviral innate immune response receptor RIG-I [KO:K12646] [EC:5.6.2.6]
126932955  interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
126936573  NLR family member X1 isoform X1 [KO:K12653]
126929120  mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
126963067  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
126960750  inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
126945470  NF-kappa-B essential modulator isoform X1 [KO:K07210]
126942055  NF-kappa-B inhibitor beta isoform X1 [KO:K02581]
126959170  NF-kappa-B inhibitor alpha [KO:K04734]
126955390  nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
126935358  transcription factor p65 isoform X1 [KO:K04735]
126939871  calcium-binding and coiled-coil domain-containing protein 2 isoform X1 [KO:K21348]
126954496  toll-like receptor 3 [KO:K05401]
126942532  TIR domain-containing adapter molecule 1 [KO:K05842]
126959960  TNF receptor-associated factor 3 isoform X1 [KO:K03174]
126930857  serine/threonine-protein kinase TBK1 isoform X1 [KO:K05410] [EC:2.7.11.10]
126938771  inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
126943112  interferon regulatory factor 3 isoform X1 [KO:K05411]
126963565  histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
126944569  CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
126936830  toll-like receptor 4 isoform X1 [KO:K10160]
126946660  toll-like receptor 7 isoform X1 [KO:K05404]
126948486  myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
126931312  interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
126935835  interferon regulatory factor 7 isoform X1 [KO:K09447]
126933365  interleukin-1 alpha isoform X1 [KO:K04383]
126933366  interleukin-1 beta [KO:K04519]
126950025  interleukin-6 isoform X1 [KO:K05405]
126949358  interleukin-12 subunit alpha isoform X1 [KO:K05406]
126957215  interleukin-12 subunit beta [KO:K05425]
126953141  tumor necrosis factor isoform X1 [KO:K03156]
126954919  interleukin-8 [KO:K10030]
126939582  C-C motif chemokine 2 [KO:K14624]
126939528  C-C motif chemokine 5 [KO:K12499]
126954877  C-X-C motif chemokine 10 [KO:K12671]
126942602  intercellular adhesion molecule 1 [KO:K06490]
126937598  interferon alpha-14 [KO:K05414]
126937600  interferon alpha-4-like [KO:K05414]
126937601  interferon alpha-17 [KO:K05414]
126937602  interferon alpha-17-like [KO:K05414]
126937603  interferon alpha-17-like [KO:K05414]
126937604  interferon alpha-17-like [KO:K05414]
126937605  LOW QUALITY PROTEIN: interferon alpha-10-like [KO:K05414]
126937606  interferon alpha-10-like [KO:K05414]
126937607  interferon alpha-1/13-like [KO:K05414]
126937608  interferon alpha-1/13 [KO:K05414]
126937609  interferon alpha-1/13-like [KO:K05414]
126937610  interferon alpha-6 [KO:K05414]
126937611  interferon alpha-4 [KO:K05414]
126937612  interferon alpha-8 [KO:K05414]
126937613  interferon alpha-2 [KO:K05414]
126937615  interferon alpha-21 [KO:K05414]
126947451  interferon alpha-10-like [KO:K05414]
126937702  interferon beta [KO:K05415]
126951662  interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
126951665  interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
126935739  tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
126942474  non-receptor tyrosine-protein kinase TYK2 isoform X1 [KO:K11219] [EC:2.7.10.2]
126939248  suppressor of cytokine signaling 3 [KO:K04696]
126932637  signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
126931203  signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
126958809  interferon regulatory factor 9 isoform X1 [KO:K04693]
126950684  interferon-induced GTP-binding protein Mx2 [KO:K14754]
126950685  interferon-induced GTP-binding protein Mx1 [KO:K14754]
126932999  double-stranded RNA-specific adenosine deaminase isoform X1 [KO:K12968] [EC:3.5.4.37]
126958947  protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
126930989  interferon gamma [KO:K04687]
126952034  interferon gamma receptor 1 isoform X1 [KO:K05132]
126951668  interferon gamma receptor 2 [KO:K05133]
126937558  tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
126944586  MHC class II transactivator isoform X1 [KO:K08060] [EC:2.7.11.1]
126952222  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
126952695  mamu class II histocompatibility antigen, DR alpha chain [KO:K06752]
126952697  HLA class II histocompatibility antigen, DQ beta 1 chain [KO:K06752]
126952698  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
126952699  HLA class II histocompatibility antigen, DRB1 beta chain isoform X1 [KO:K06752]
126952700  HLA class II histocompatibility antigen, DRB1 beta chain isoform X1 [KO:K06752]
126952701  HLA class II histocompatibility antigen, DQ beta 1 chain isoform X1 [KO:K06752]
126952702  HLA class II histocompatibility antigen, DQ alpha 1 chain isoform X1 [KO:K06752]
126952777  HLA class II histocompatibility antigen, DP alpha 1 chain isoform X1 [KO:K06752]
126952785  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
126952790  HLA class II histocompatibility antigen, DM beta chain [KO:K06752]
126952792  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
126952793  HLA class II histocompatibility antigen, DP beta 1 chain [KO:K06752]
126952833  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
126943144  NACHT, LRR and PYD domains-containing protein 3 [KO:K12800]
126944252  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
126936244  caspase-1-like [KO:K01370] [EC:3.4.22.36]
126936247  LOW QUALITY PROTEIN: caspase-1-like [KO:K01370] [EC:3.4.22.36]
126936524  caspase-1-like [KO:K01370] [EC:3.4.22.36]
126935802  interleukin-18 isoform X1 [KO:K05482]
126937879  interleukin-33 isoform X1 [KO:K12967]
126961422  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
126956531  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
126942202  phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
126947557  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
126952893  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
126948170  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
126943096  RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
126959416  RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
126942032  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
126953804  G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
126930400  cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
126951304  cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
126948360  tumor necrosis factor ligand superfamily member 10 [KO:K04721]
126961267  tumor necrosis factor receptor superfamily member 10A isoform X1 [KO:K04722]
126961271  tumor necrosis factor receptor superfamily member 10B isoform X1 [KO:K04722]
126941397  tumor necrosis factor ligand superfamily member 6 [KO:K04389]
126963192  tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
126930443  tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
126945020  tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
126935972  FAS-associated death domain protein [KO:K02373]
126932110  caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
126929772  BH3-interacting domain death agonist [KO:K04726]
126943600  apoptosis regulator BAX isoform X1 [KO:K02159]
126952802  bcl-2 homologous antagonist/killer [KO:K14021]
126956005  voltage-dependent anion-selective channel protein 1 [KO:K05862]
126955617  ADP/ATP translocase 4 isoform X1 [KO:K05863]
126955724  ADP/ATP translocase 1 [KO:K05863]
126946121  ADP/ATP translocase 2 [KO:K05863]
126946856  ADP/ATP translocase 3 [KO:K05863]
126947143  ADP/ATP translocase 3 [KO:K05863]
126949081  cytochrome c-like [KO:K08738]
126961774  cytochrome c-like [KO:K08738]
126936610  cytochrome c-like [KO:K08738]
126937973  cytochrome c-like [KO:K08738]
126944405  cytochrome c-like [KO:K08738]
126932751  cytochrome c-like [KO:K08738]
126951393  cytochrome c [KO:K08738]
126947125  cytochrome c-like [KO:K08738]
126941401  cytochrome c-like [KO:K08738]
126952962  cytochrome c-like [KO:K08738]
126942126  cytochrome c-like [KO:K08738]
126931282  apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
126929188  LOW QUALITY PROTEIN: caspase-9 [KO:K04399] [EC:3.4.22.62]
126954341  caspase-3 [KO:K02187] [EC:3.4.22.56]
126950515  cleavage and polyadenylation specificity factor subunit 4 isoform X1 [KO:K14404]
126939916  putative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X1 [KO:K14404]
126944331  embryonic polyadenylate-binding protein 2 [KO:K14396]
126958242  bcl-2-like protein 2 isoform X1 [KO:K14396]
126945855  nuclear RNA export factor 5-like [KO:K14284]
126945992  nuclear RNA export factor 2 isoform X1 [KO:K14284]
126945994  nuclear RNA export factor 3 isoform X1 [KO:K14284]
126935466  nuclear RNA export factor 1 [KO:K14284]
126945321  NTF2-related export protein 2 isoform X1 [KO:K14285]
126929320  NTF2-related export protein 1 [KO:K14285]
126941751  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1 [KO:K15047]
126929154  mRNA export factor RAE1 isoform X1 [KO:K14298]
126935015  LOW QUALITY PROTEIN: nuclear pore complex protein Nup98-Nup96 [KO:K14297]
126934173  radical S-adenosyl methionine domain-containing protein 2 [KO:K15045]
126937977  farnesyl pyrophosphate synthase-like [KO:K00787] [EC:2.5.1.1 2.5.1.10]
126949883  LOW QUALITY PROTEIN: farnesyl pyrophosphate synthase-like [KO:K00787] [EC:2.5.1.1 2.5.1.10]
126945661  farnesyl pyrophosphate synthase-like [KO:K00787] [EC:2.5.1.1 2.5.1.10]
126934144  farnesyl pyrophosphate synthase isoform X1 [KO:K00787] [EC:2.5.1.1 2.5.1.10]
126938340  protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
126949054  RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
126957976  dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
126942673  dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
126944456  mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
126929669  mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
126932601  actin, cytoplasmic 2 [KO:K05692]
126939111  actin, cytoplasmic 2 [KO:K05692]
126950494  actin, cytoplasmic 1 isoform X1 [KO:K05692]
126958358  LOW QUALITY PROTEIN: actin-like [KO:K05692]
126957995  ras-related protein Rab-11A [KO:K07904]
126942786  ras-related protein Rab-11B [KO:K07905]
126933589  exportin-1 isoform X1 [KO:K14290]
126949213  importin subunit alpha-5 [KO:K23940]
126938344  LOW QUALITY PROTEIN: importin subunit alpha-1-like [KO:K15043]
126938347  importin subunit alpha-1 [KO:K15043]
126950542  importin subunit alpha-8 [KO:K15043]
126957364  importin subunit alpha-7 isoform X1 [KO:K15042]
126952198  importin subunit alpha-6 isoform X1 [KO:K15042]
126941363  importin subunit alpha-7-like [KO:K15042]
Compound
C00027  Hydrogen peroxide
C00080  H+
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:24225499
  Authors
Edinger TO, Pohl MO, Stertz S
  Title
Entry of influenza A virus: host factors and antiviral targets.
  Journal
J Gen Virol 95:263-77 (2014)
DOI:10.1099/vir.0.059477-0
Reference
PMID:19565019
  Authors
Kido H, Okumura Y, Takahashi E, Pan HY, Wang S, Chida J, Le TQ, Yano M
  Title
Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.
  Journal
J Mol Genet Med 3:167-75 (2008)
Reference
PMID:27751627
  Authors
Ramakrishnan B, Viswanathan K, Tharakaraman K, Dancik V, Raman R, Babcock GJ, Shriver Z, Sasisekharan R
  Title
A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza.
  Journal
Trends Microbiol 24:933-943 (2016)
DOI:10.1016/j.tim.2016.09.003
Reference
PMID:18588994
  Authors
Thanh TT, van Doorn HR, de Jong MD
  Title
Human H5N1 influenza: current insight into pathogenesis.
  Journal
Int J Biochem Cell Biol 40:2671-4 (2008)
DOI:10.1016/j.biocel.2008.05.019
Reference
PMID:23977434
  Authors
Michael P, Brabant D, Bleiblo F, Ramana CV, Rutherford M, Khurana S, Tai TC, Kumar A, Kumar A
  Title
Influenza A induced cellular signal transduction pathways.
  Journal
J Thorac Dis 5 Suppl 2:S132-41 (2013)
DOI:10.3978/j.issn.2072-1439.2013.07.42
Reference
PMID:20020828
  Authors
Hale BG, Albrecht RA, Garcia-Sastre A
  Title
Innate immune evasion strategies of influenza viruses.
  Journal
Future Microbiol 5:23-41 (2010)
DOI:10.2217/fmb.09.108
Reference
PMID:21698289
  Authors
Sharma K, Tripathi S, Ranjan P, Kumar P, Garten R, Deyde V, Katz JM, Cox NJ, Lal RB, Sambhara S, Lal SK
  Title
Influenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activation.
  Journal
PLoS One 6:e20215 (2011)
DOI:10.1371/journal.pone.0020215
Reference
PMID:19782761
  Authors
Ehrhardt C, Seyer R, Hrincius ER, Eierhoff T, Wolff T, Ludwig S
  Title
Interplay between influenza A virus and the innate immune signaling.
  Journal
Microbes Infect 12:81-7 (2010)
DOI:10.1016/j.micinf.2009.09.007
Reference
PMID:23170167
  Authors
van de Sandt CE, Kreijtz JH, Rimmelzwaan GF
  Title
Evasion of influenza A viruses from innate and adaptive immune responses.
  Journal
Viruses 4:1438-76 (2012)
DOI:10.3390/v4091438
Reference
PMID:30487536
  Authors
Long JS, Mistry B, Haslam SM, Barclay WS
  Title
Host and viral determinants of influenza A virus species specificity.
  Journal
Nat Rev Microbiol 17:67-81 (2019)
DOI:10.1038/s41579-018-0115-z
Reference
PMID:29556226
  Authors
Chen X, Liu S, Goraya MU, Maarouf M, Huang S, Chen JL
  Title
Host Immune Response to Influenza A Virus Infection.
  Journal
Front Immunol 9:320 (2018)
DOI:10.3389/fimmu.2018.00320
Reference
PMID:20130137
  Authors
Lu X, Masic A, Li Y, Shin Y, Liu Q, Zhou Y
  Title
The PI3K/Akt pathway inhibits influenza A virus-induced Bax-mediated apoptosis by negatively regulating the JNK pathway via ASK1.
  Journal
J Gen Virol 91:1439-49 (2010)
DOI:10.1099/vir.0.018465-0
Reference
PMID:18980544
  Authors
Ichinohe T, Iwasaki A, Hasegawa H
  Title
Innate sensors of influenza virus: clues to developing better intranasal vaccines.
  Journal
Expert Rev Vaccines 7:1435-45 (2008)
DOI:10.1586/14760584.7.9.1435
Reference
PMID:27231932
  Authors
Le Sage V, Cinti A, Amorim R, Mouland AJ
  Title
Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway.
  Journal
Viruses 8:E152 (2016)
DOI:10.3390/v8060152
Reference
PMID:30510918
  Authors
Fan Y, Sanyal S, Bruzzone R
  Title
Breaking Bad: How Viruses Subvert the Cell Cycle.
  Journal
Front Cell Infect Microbiol 8:396 (2018)
DOI:10.3389/fcimb.2018.00396
Reference
PMID:21971186
  Authors
Varga ZT, Palese P
  Title
The influenza A virus protein PB1-F2: killing two birds with one stone?
  Journal
Virulence 2:542-6 (2011)
DOI:10.4161/viru.2.6.17812
Reference
PMID:30254192
  Authors
Atkin-Smith GK, Duan M, Chen W, Poon IKH
  Title
The induction and consequences of Influenza A virus-induced cell death.
  Journal
Cell Death Dis 9:1002 (2018)
DOI:10.1038/s41419-018-1035-6
Reference
PMID:30545063
  Authors
Nogales A, Martinez-Sobrido L, Topham DJ, DeDiego ML
  Title
Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins.
  Journal
Viruses 10:E708 (2018)
DOI:10.3390/v10120708
Reference
PMID:21253874
  Authors
Dai X, Zhang L, Hong T
  Title
Host cellular signaling induced by influenza virus.
  Journal
Sci China Life Sci 54:68-74 (2011)
DOI:10.1007/s11427-010-4116-z
Reference
PMID:26008706
  Authors
Li J, Yu M, Zheng W, Liu W
  Title
Nucleocytoplasmic shuttling of influenza A virus proteins.
  Journal
Viruses 7:2668-82 (2015)
DOI:10.3390/v7052668
Reference
PMID:30079062
  Authors
Dou D, Revol R, Ostbye H, Wang H, Daniels R
  Title
Influenza A Virus Cell Entry, Replication, Virion Assembly and Movement.
  Journal
Front Immunol 9:1581 (2018)
DOI:10.3389/fimmu.2018.01581
Reference
PMID:23236273
  Authors
Paterson D, Fodor E
  Title
Emerging roles for the influenza A virus nuclear export protein (NEP).
  Journal
PLoS Pathog 8:e1003019 (2012)
DOI:10.1371/journal.ppat.1003019
Related
pathway
mthb00900  Terpenoid backbone biosynthesis
mthb03013  Nucleocytoplasmic transport
mthb03015  mRNA surveillance pathway
mthb04010  MAPK signaling pathway
mthb04110  Cell cycle
mthb04144  Endocytosis
mthb04210  Apoptosis
mthb04620  Toll-like receptor signaling pathway
mthb04621  NOD-like receptor signaling pathway
mthb04622  RIG-I-like receptor signaling pathway
mthb04630  JAK-STAT signaling pathway
mthb05416  Viral myocarditis
KO pathway
ko05164   
LinkDB

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