KEGG   PATHWAY: nle00190
Entry
nle00190                    Pathway                                
Name
Oxidative phosphorylation - Nomascus leucogenys (northern white-cheeked gibbon)
Class
Metabolism; Energy metabolism
Pathway map
nle00190  Oxidative phosphorylation
nle00190

Module
nle_M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:nle00190]
nle_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:nle00190]
nle_M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:nle00190]
nle_M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:nle00190]
nle_M00148  Succinate dehydrogenase (ubiquinone) [PATH:nle00190]
nle_M00151  Cytochrome bc1 complex respiratory unit [PATH:nle00190]
nle_M00152  Cytochrome bc1 complex [PATH:nle00190]
nle_M00154  Cytochrome c oxidase [PATH:nle00190]
nle_M00158  F-type ATPase, eukaryotes [PATH:nle00190]
nle_M00160  V-type ATPase, eukaryotes [PATH:nle00190]
Organism
Nomascus leucogenys (northern white-cheeked gibbon) [GN:nle]
Gene
16545241  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
16545240  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
16545229  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
16545234  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
16545235  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
16545233  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
16545232  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
100581296  NDUFS1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial [KO:K03934] [EC:7.1.1.2]
100603263  NDUFS2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X1 [KO:K03935] [EC:7.1.1.2]
100581013  NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial [KO:K03936] [EC:7.1.1.2]
100590696  NDUFS4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform X1 [KO:K03937]
100607157  NADH dehydrogenase [ubiquinone] iron-sulfur protein 5-like [KO:K03938]
100580677  NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
115837547  NDUFS5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
100601147  NDUFS6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
100601339  NDUFS7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X1 [KO:K03940] [EC:7.1.1.2]
100583320  NDUFS8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1 [KO:K03941] [EC:7.1.1.2]
100580871  NDUFV1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial isoform X1 [KO:K03942] [EC:7.1.1.2]
100600027  NDUFV2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:7.1.1.2]
100596062  NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X2 [KO:K03944]
115833278  NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
100605663  NDUFA2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946]
100601477  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2-like [KO:K03946]
100606613  NDUFA3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
115834433  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
100588090  NDUFA4; cytochrome c oxidase subunit NDUFA4 [KO:K03948]
115836001  cytochrome c oxidase subunit NDUFA4-like [KO:K03948]
100604070  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5-like isoform X1 [KO:K03949]
100583725  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
100580691  NDUFA5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
100587987  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5-like isoform X1 [KO:K03949]
100606552  NDUFA6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
100588818  NDUFA7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
100582034  NDUFA8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
100586090  NDUFA9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
100602594  NDUFA10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial isoform X1 [KO:K03954]
100598663  NDUFAB1; acyl carrier protein, mitochondrial [KO:K03955]
100582744  acyl carrier protein, mitochondrial [KO:K03955]
100586588  NDUFA11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
100579680  NDUFA12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
100581538  NDUFA13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353]
100603049  NDUFB1; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957]
115834798  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957]
100583181  NDUFB2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial isoform X2 [KO:K03958]
100591674  NDUFB3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [KO:K03959]
100595831  NDUFB4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
100592262  NDUFB5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform X1 [KO:K03961]
100597315  NDUFB6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962]
100607066  NDUFB7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
100603586  NDUFB8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964]
100584104  NDUFB9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965]
100602977  NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 isoform X1 [KO:K03966]
100598012  NDUFB11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
100583388  NDUFC1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
100584534  NDUFC2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
100593202  SDHA; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1 [KO:K00234] [EC:1.3.5.1]
115834056  LOW QUALITY PROTEIN: succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial-like [KO:K00234] [EC:1.3.5.1]
100600690  LOW QUALITY PROTEIN: succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial-like [KO:K00234] [EC:1.3.5.1]
101177207  LOW QUALITY PROTEIN: succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial-like [KO:K00234] [EC:1.3.5.1]
115833880  LOW QUALITY PROTEIN: succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial-like [KO:K00234] [EC:1.3.5.1]
100582706  SDHB; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
100607083  SDHC; succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X1 [KO:K00236]
100590500  succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial-like isoform X2 [KO:K00237]
100584747  SDHD; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform X1 [KO:K00237]
100605926  cytochrome b-c1 complex subunit Rieske, mitochondrial isoform X1 [KO:K00411] [EC:7.1.1.8]
16545231  CYTB; cytochrome b [KO:K00412]
100604545  cytochrome c1, heme protein, mitochondrial isoform X1 [KO:K00413]
100593270  cytochrome b-c1 complex subunit 1, mitochondrial isoform X1 [KO:K00414]
100592631  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
100589568  cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [KO:K00416]
100604897  cytochrome b-c1 complex subunit 7 [KO:K00417]
100601353  cytochrome b-c1 complex subunit 8 [KO:K00418]
100601682  cytochrome b-c1 complex subunit 9 isoform X1 [KO:K00419]
100605939  cytochrome b-c1 complex subunit 10 [KO:K00420]
100586480  protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.141]
16545230  COX3; cytochrome c oxidase subunit III [KO:K02262]
16545239  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
16545238  COX2; cytochrome c oxidase subunit II [KO:K02261]
100597359  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
100584639  cytochrome c oxidase subunit 4 isoform 2, mitochondrial [KO:K02263]
100582955  cytochrome c oxidase subunit 5A, mitochondrial-like [KO:K02264]
100588957  cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
100595152  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
100595948  cytochrome c oxidase subunit 6A2, mitochondrial [KO:K02266]
100582575  cytochrome c oxidase subunit 6A1, mitochondrial [KO:K02266]
105738321  cytochrome c oxidase subunit 6B2 [KO:K02267]
100606627  cytochrome c oxidase subunit 6B1 [KO:K02267]
100588890  cytochrome c oxidase subunit 6C [KO:K02268]
100585631  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
100596162  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
100596832  cytochrome c oxidase subunit 7A1, mitochondrial [KO:K02270]
100602515  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
100591930  cytochrome c oxidase subunit 7B2, mitochondrial [KO:K02271]
115837591  cytochrome c oxidase subunit 7B, mitochondrial-like [KO:K02271]
100579903  cytochrome c oxidase subunit 7C, mitochondrial [KO:K02272]
115832449  cytochrome c oxidase subunit 8C, mitochondrial [KO:K02273]
115834767  cytochrome c oxidase subunit 8A, mitochondrial [KO:K02273]
115833541  cytochrome c oxidase subunit 8A, mitochondrial-like [KO:K02273]
100592800  cytochrome c oxidase assembly protein COX11, mitochondrial [KO:K02258]
100599631  cytochrome c oxidase assembly protein COX15 homolog isoform X1 [KO:K02259] [EC:1.17.99.9]
100604305  cytochrome c oxidase copper chaperone [KO:K02260]
100603746  cytochrome c-like [KO:K08738]
100600457  cytochrome c-like [KO:K08738]
100580069  cytochrome c [KO:K08738]
100598207  cytochrome c-like [KO:K08738]
100599727  cytochrome c-like [KO:K08738]
101179576  cytochrome c-like [KO:K08738]
100604294  cytochrome c-like [KO:K08738]
100606561  ATP5F1A; ATP synthase subunit alpha, mitochondrial [KO:K02132]
100583743  ATP5F1B; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
100584984  ATP5F1C; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136]
100600336  ATP5F1D; ATP synthase subunit delta, mitochondrial isoform X1 [KO:K02134]
100607086  ATP5F1E; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
100587731  ATP5PO; ATP synthase subunit O, mitochondrial [KO:K02137]
16545236  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
100601615  ATP5PB; ATP synthase F(0) complex subunit B1, mitochondrial [KO:K02127]
100581336  ATP5MC1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
100584861  ATP5MC3; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128]
100580736  ATP5MC2; ATP synthase F(0) complex subunit C2, mitochondrial isoform X1 [KO:K02128]
100580901  ATP5PD; ATP synthase subunit d, mitochondrial [KO:K02138]
100599795  ATP5ME; ATP synthase subunit e, mitochondrial [KO:K02129]
100604641  ATP synthase subunit f, mitochondrial-like isoform X1 [KO:K02130]
100596139  ATP5MF; ATP synthase subunit f, mitochondrial [KO:K02130]
100582261  ATP5MGL; putative ATP synthase subunit g 2, mitochondrial [KO:K02140]
100583412  ATP5MG; ATP synthase subunit g, mitochondrial [KO:K02140]
100586928  ATP5PF; ATP synthase-coupling factor 6, mitochondrial isoform X2 [KO:K02131]
16545237  ATP8; ATP synthase F0 subunit 8 [KO:K02125]
100591065  ATP6V1A; V-type proton ATPase catalytic subunit A [KO:K02145] [EC:7.1.2.2]
100589839  ATP6V1B2; V-type proton ATPase subunit B, brain isoform [KO:K02147]
100581139  ATP6V1B1; V-type proton ATPase subunit B, kidney isoform [KO:K02147]
100602458  ATP6V1C1; V-type proton ATPase subunit C 1 [KO:K02148]
100592578  ATP6V1C2; V-type proton ATPase subunit C 2 isoform X1 [KO:K02148]
100587148  ATP6V1D; V-type proton ATPase subunit D [KO:K02149]
100607588  ATP6V1E2; V-type proton ATPase subunit E 2 [KO:K02150]
100593410  ATP6V1E1; V-type proton ATPase subunit E 1 [KO:K02150]
100595027  ATP6V1F; V-type proton ATPase subunit F isoform X1 [KO:K02151]
100581626  ATP6V1G2; V-type proton ATPase subunit G 2 [KO:K02152]
100605208  ATP6V1G3; V-type proton ATPase subunit G 3 isoform X2 [KO:K02152]
100596071  ATP6V1G1; V-type proton ATPase subunit G 1 [KO:K02152]
100587992  ATP6V1H; V-type proton ATPase subunit H isoform X1 [KO:K02144]
100598544  ATP6V0A4; V-type proton ATPase 116 kDa subunit a [KO:K02154]
100583652  TCIRG1; V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
100598741  ATP6V0A2; V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
100603157  ATP6V0A1; V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
100581942  ATP6V0C; V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
101178102  V-type proton ATPase 16 kDa proteolipid subunit-like [KO:K02155]
100597955  ATP6V0B; V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
100583598  ATP6V0D1; V-type proton ATPase subunit d 1 [KO:K02146]
100580060  ATP6V0D2; V-type proton ATPase subunit d 2 [KO:K02146]
100590961  V-type proton ATPase subunit e 2 [KO:K02153]
100592479  ATP6V0E1; V-type proton ATPase subunit e 1 [KO:K02153]
100593870  ATP6AP1; V-type proton ATPase subunit S1 [KO:K03662]
100593416  ATP4A; potassium-transporting ATPase alpha chain 1 isoform X1 [KO:K01542] [EC:7.2.2.19]
100603851  ATP4B; potassium-transporting ATPase subunit beta [KO:K01543] [EC:7.2.2.19]
100582869  ATP12A; potassium-transporting ATPase alpha chain 2 [KO:K01544] [EC:7.2.2.19]
105739360  inorganic pyrophosphatase-like [KO:K01507] [EC:3.6.1.1]
100603716  PPA2; inorganic pyrophosphatase 2, mitochondrial isoform X1 [KO:K01507] [EC:3.6.1.1]
100587760  PPA1; inorganic pyrophosphatase [KO:K01507] [EC:3.6.1.1]
100594200  LHPP; phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X2 [KO:K11725] [EC:3.6.1.1 3.1.3.-]
Compound
C00001  H2O
C00002  ATP
C00003  NAD+
C00004  NADH
C00007  Oxygen
C00008  ADP
C00009  Orthophosphate
C00013  Diphosphate
C00042  Succinate
C00080  H+
C00122  Fumarate
C00536  Triphosphate
Reference
PMID:16469879
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
PMID:16584177
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
ko00190   
LinkDB

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