KEGG   PATHWAY: rut00630
Entry
rut00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Ruegeria sp. THAF33
Class
Metabolism; Carbohydrate metabolism
Pathway map
rut00630  Glyoxylate and dicarboxylate metabolism
rut00630

Module
rut_M00373  Ethylmalonyl pathway [PATH:rut00630]
rut_M00621  Glycine cleavage system [PATH:rut00630]
rut_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:rut00630]
Other DBs
GO: 0046487 0043648
Organism
Ruegeria sp. THAF33 [GN:rut]
Gene
FIU92_06195  acsA2; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
FIU92_11060  acsA3; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
FIU92_11230  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
FIU92_05010  mdh2; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
FIU92_01305  mdh1; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
FIU92_08290  gltA2; Citrate synthase [KO:K01647] [EC:2.3.3.1]
FIU92_09730  acnA; Aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
FIU92_00405  acnB; Aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
FIU92_19880  sucD2; Succinyl-CoA ligase [ADP-forming] subunit alpha [KO:K08692] [EC:6.2.1.9]
FIU92_19885  sucC2; Succinyl-CoA ligase [ADP-forming] subunit beta [KO:K14067] [EC:6.2.1.9]
FIU92_04565  fadA; Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
FIU92_17455  bktB; Beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
FIU92_14500  thlA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
FIU92_01165  phbA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
FIU92_01160  fabG3; 3-oxoacyl-[acyl-carrier-protein] reductase FabG [KO:K00023] [EC:1.1.1.36]
FIU92_13070  phaJ; (R)-specific enoyl-CoA hydratase [KO:K17865] [EC:4.2.1.55]
FIU92_01410  ccrA1; Crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
FIU92_12830  Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein [KO:K05606] [EC:5.1.99.1]
FIU92_01400  scpA1; Methylmalonyl-CoA mutase [KO:K14447] [EC:5.4.99.63]
FIU92_02785  mmgC1; Acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
FIU92_01335  hypothetical protein [KO:K14449] [EC:4.2.1.148]
FIU92_19865  mcl3; Malyl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
FIU92_13270  mcl2; Malyl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
FIU92_01320  mcl1; (3S)-malyl-CoA thioesterase [KO:K14451] [EC:3.1.2.30]
FIU92_11735  accA2; Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K01965] [EC:6.4.1.3]
FIU92_11760  accD1; putative propionyl-CoA carboxylase beta chain 5 [KO:K01966] [EC:6.4.1.3 2.1.3.15]
FIU92_11725  scpA3; Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
FIU92_17115  putative FAD-linked oxidoreductase [KO:K00104] [EC:1.1.99.14]
FIU92_17120  putative FAD-linked oxidoreductase [KO:K11472] [EC:1.1.99.14]
FIU92_17125  lutA; Lactate utilization protein A [KO:K11473] [EC:1.1.99.14]
FIU92_12185  Putative 2-hydroxyacid dehydrogenase [KO:K00015] [EC:1.1.1.26]
FIU92_01590  ghrA1; Glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
FIU92_03355  ghrA2; Glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
FIU92_10860  gph1; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
FIU92_11080  gph2; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
FIU92_12645  gph3; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
FIU92_03845  Soluble hydrogenase 42 kDa subunit [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
FIU92_20540  Soluble hydrogenase 42 kDa subunit [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
FIU92_09650  glnA1; Glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
FIU92_10325  puuA2; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
FIU92_10335  puuA3; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
FIU92_12120  glnA2; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
FIU92_04980  puuA1; Gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
FIU92_04480  glyA1; Serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
FIU92_19820  glyA3; Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
FIU92_19870  glyA4; Serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
FIU92_18105  glyA2; Serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
FIU92_19855  gcvP2; Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
FIU92_14965  gcvP1; Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
FIU92_19845  gcvT4; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
FIU92_14975  gcvT2; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
FIU92_09330  lpd2; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
FIU92_19825  lpd3; Dihydrolipoyl dehydrogenase 3 [KO:K00382] [EC:1.8.1.4]
FIU92_01260  lpd1; Dihydrolipoyl dehydrogenase 3 [KO:K00382] [EC:1.8.1.4]
FIU92_19850  gcvH2; Glycine cleavage system H protein [KO:K02437]
FIU92_14970  gcvH1; Glycine cleavage system H protein [KO:K02437]
FIU92_13750  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
FIU92_12040  ttuD; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
FIU92_10790  aldA1; Lactaldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
FIU92_03840  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
FIU92_03325  fdhF; Formate dehydrogenase H [KO:K00123] [EC:1.17.1.9]
FIU92_06110  fdoG; Formate dehydrogenase-O major subunit precursor [KO:K00123] [EC:1.17.1.9]
FIU92_03320  nqo1; NADH-quinone oxidoreductase subunit 1 [KO:K22515] [EC:1.17.1.9]
FIU92_06105  fdhB1; Formate dehydrogenase iron-sulfur subunit [KO:K00124]
FIU92_06095  fdoI; Formate dehydrogenase, cytochrome b556(fdo) subunit [KO:K00127]
FIU92_17425  nlhH2; Carboxylesterase NlhH [KO:K01432] [EC:3.5.1.9]
FIU92_18835  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
rut00010  Glycolysis / Gluconeogenesis
rut00020  Citrate cycle (TCA cycle)
rut00030  Pentose phosphate pathway
rut00053  Ascorbate and aldarate metabolism
rut00071  Fatty acid degradation
rut00230  Purine metabolism
rut00250  Alanine, aspartate and glutamate metabolism
rut00260  Glycine, serine and threonine metabolism
rut00620  Pyruvate metabolism
rut00750  Vitamin B6 metabolism
rut00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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