KEGG   PATHWAY: sasa04625
Entry
sasa04625                   Pathway                                
Name
C-type lectin receptor signaling pathway - Salmo salar (Atlantic salmon)
Description
C-type lectin receptors (CLRs) are a large superfamily of proteins characterized by the presence of one or more C-type lectin-like domains (CTLDs). CLRs function as pattern-recognition receptors (PRRs) for pathogen-derived ligands in dendric cells, macrophages, neutrophils, etc., such as Dectin-1 and Dectin-2 for recognition of fungi-derived B-glucan and high mannose-type carbohydrates. Upon ligand binding, CLRs stimulate intracellular signaling cascades that induce the production of inflammatory cytokines and chemokines, consequently triggering innate and adaptive immunity to pathogens.
Class
Organismal Systems; Immune system
Pathway map
sasa04625  C-type lectin receptor signaling pathway
sasa04625

Organism
Salmo salar (Atlantic salmon) [GN:sasa]
Gene
106573361  GTPase HRas-like [KO:K02833]
100196603  rash; GTPase HRas [KO:K02833]
106601908  GTPase HRas-like [KO:K07827]
106606379  GTPase HRas-like [KO:K07827]
106561428  GTPase KRas [KO:K07827]
100380437  rask; GTPase KRas [KO:K07827]
106574266  ras-related protein M-Ras [KO:K07831]
106575193  ras-related protein M-Ras-like [KO:K07831]
106582394  ras-related protein M-Ras-like [KO:K07831]
106586304  ras-related protein M-Ras-like [KO:K07831]
106600695  rras; related RAS viral (r-ras) oncogene homolog [KO:K07830]
106562341  ras-related protein R-Ras2-like [KO:K07830]
106587534  ras-related protein R-Ras2 [KO:K07830]
106583918  ras-related protein R-Ras-like [KO:K07830]
106571905  RAF1b; RAF proto-oncogene serine/threonine-protein kinase-like [KO:K04366] [EC:2.7.11.1]
106566757  RAF1a; RAF proto-oncogene serine/threonine-protein kinase-like [KO:K04366] [EC:2.7.11.1]
100136351  raf1; Raf-1 proto-oncogene, serine/threonine kinase [KO:K04366] [EC:2.7.11.1]
106608684  putative transcription factor p65 homolog [KO:K04735]
106577543  transcription factor p65-like [KO:K04735]
100380715  relb; RELB proto-oncogene, NF-kB subunit [KO:K09253]
106580951  uncharacterized LOC106580951 [KO:K05406]
106604286  interleukin-12 subunit beta-like [KO:K05425]
106603888  IL12B; interleukin-12 subunit beta-like [KO:K05425]
106607975  IL12B; interleukin-12 subunit beta-like [KO:K05425]
106612126  interleukin-12 subunit beta-like [KO:K05425]
106567437  interleukin-12 subunit beta-like [KO:K05425]
106562915  IL-1b3; interleukin-1 beta-like [KO:K04519]
106570815  interleukin-1 beta-like [KO:K04519]
100136449  interleukin-1 beta [KO:K04519]
100380388  syk; spleen associated tyrosine kinase [KO:K05855] [EC:2.7.10.2]
106562610  tyrosine-protein phosphatase non-receptor type 11-like [KO:K07293] [EC:3.1.3.48]
106572187  tyrosine-protein phosphatase non-receptor type 11-like [KO:K07293] [EC:3.1.3.48]
106568295  tyrosine-protein phosphatase non-receptor type 11 [KO:K07293] [EC:3.1.3.48]
106566948  tyrosine-protein phosphatase non-receptor type 11-like [KO:K07293] [EC:3.1.3.48]
100380862  m3k14; mitogen-activated protein kinase kinase kinase 14 [KO:K04466] [EC:2.7.11.25]
106607326  mitogen-activated protein kinase kinase kinase 14-like [KO:K04466] [EC:2.7.11.25]
106579033  uncharacterized LOC106579033 [KO:K04466] [EC:2.7.11.25]
106579286  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
106579422  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
106589264  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
106606070  nuclear factor NF-kappa-B p100 subunit-like [KO:K04469]
100380298  nfkb2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 [KO:K04469]
106573684  plcg2; phospholipase C gamma 2 [KO:K05859] [EC:3.1.4.11]
106583165  inositol 1,4,5-trisphosphate receptor type 1-like [KO:K04958]
106565476  inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
106582863  inositol 1,4,5-trisphosphate receptor type 1-like [KO:K04958]
106565749  inositol 1,4,5-trisphosphate receptor type 1-like [KO:K04958]
100196824  itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
106573309  inositol 1,4,5-trisphosphate receptor type 2-like [KO:K04959]
106572092  inositol 1,4,5-trisphosphate receptor type 3-like [KO:K04960]
106566485  inositol 1,4,5-trisphosphate receptor type 3-like [KO:K04960]
106601272  CALM; calmodulin [KO:K02183]
106605143  CALM; calmodulin [KO:K02183]
106603160  calmodulin [KO:K02183]
106608223  CALM; calmodulin [KO:K02183]
106611171  calm1; calmodulin 1 [KO:K02183]
100195847  call4; Calmodulin-like protein 4 [KO:K02183]
106566003  calml6; calmodulin like 6 [KO:K02183]
106612378  CALM; calmodulin [KO:K02183]
106563500  CALM; calmodulin [KO:K02183]
106562770  calmodulin-like protein 4 [KO:K02183]
106560757  calml4; calmodulin like 4 [KO:K02183]
100194628  calm2; calmodulin 2 [KO:K02183]
100194629  CALM; calmodulin 2 (phosphorylase kinase, delta)-3 [KO:K02183]
106597685  calmodulin-like protein 4 [KO:K02183]
106597678  calmodulin-like protein 4 [KO:K02183]
106604405  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like [KO:K04348] [EC:3.1.3.16]
106603034  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like [KO:K04348] [EC:3.1.3.16]
106608629  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [KO:K04348] [EC:3.1.3.16]
106612112  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like [KO:K04348] [EC:3.1.3.16]
106580517  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like [KO:K04348] [EC:3.1.3.16]
106563625  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like [KO:K04348] [EC:3.1.3.16]
106568136  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like [KO:K04348] [EC:3.1.3.16]
106585124  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like [KO:K04348] [EC:3.1.3.16]
100196828  ppp3ca; protein phosphatase 3 catalytic subunit alpha [KO:K04348] [EC:3.1.3.16]
100195067  pp2bc; Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform [KO:K04348] [EC:3.1.3.16]
106586010  calcineurin subunit B type 1 [KO:K06268]
106578839  calcineurin subunit B type 1-like [KO:K06268]
100380679  canb1; calcineurin subunit B type 1 [KO:K06268]
106589933  calcineurin subunit B type 1-like [KO:K06268]
106583607  nuclear factor of activated T-cells, cytoplasmic 1-like [KO:K04446]
106605067  nuclear factor of activated T-cells, cytoplasmic 1-like [KO:K04446]
106569777  nuclear factor of activated T-cells, cytoplasmic 1-like [KO:K04446]
106588230  nuclear factor of activated T-cells, cytoplasmic 1-like [KO:K04446]
106572627  nuclear factor of activated T-cells, cytoplasmic 2-like [KO:K17332]
106567114  nuclear factor of activated T-cells, cytoplasmic 2-like [KO:K17332]
106583670  nuclear factor of activated T-cells, cytoplasmic 2-like [KO:K17332]
106573250  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
106561519  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
106562446  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
106587624  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
106600383  nuclear factor of activated T-cells, cytoplasmic 4-like [KO:K17334]
106569373  nfatc4; nuclear factor of activated T-cells 4 [KO:K17334]
106566262  interleukin-10-like [KO:K05443]
100136512  il-10; interleukin-10 [KO:K05443]
106594794  IL-10; interleukin-10-like [KO:K05443]
100194495  krox20; early growth response protein 2b [KO:K12496]
106607870  early growth response protein 2b-like [KO:K12496]
106577138  early growth response protein 2b-like [KO:K12496]
106598760  early growth response protein 2b [KO:K12496]
106592202  early growth response protein 2b-like [KO:K12496]
106579855  early growth response protein 3-like [KO:K12497]
106585589  early growth response protein 3-like [KO:K12497]
106560558  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
106599098  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
100136456  cox-2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
106583970  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
106565545  protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
106565827  protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
106583214  KPCD; protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
106595901  protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
100195900  kpcd; protein kinase C delta type [KO:K06068] [EC:2.7.11.13]
106570952  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
106600714  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
106592057  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
100380511  mk03; Mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
106573513  uncharacterized LOC106573513 [KO:K12799]
106573461  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
106582385  ASC; apoptosis-associated speck-like protein containing a CARD [KO:K12799]
106605228  ASC; apoptosis-associated speck-like protein containing a CARD [KO:K12799]
106568745  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
106573458  uncharacterized LOC106573458 [KO:K12799]
106573462  ASC; uncharacterized LOC106573462 [KO:K12799]
106612902  caspase-1-like [KO:K01370] [EC:3.4.22.36]
100195248  card9; caspase recruitment domain family, member 9 [KO:K12794]
106585631  caspase recruitment domain-containing protein 9-like [KO:K12794]
106600420  B-cell lymphoma/leukemia 10-like [KO:K07368]
106610232  B-cell lymphoma/leukemia 10-like [KO:K07368]
106610233  B-cell lymphoma/leukemia 10-like [KO:K07368]
106569306  B-cell lymphoma/leukemia 10-like [KO:K07368]
100196227  bcl10; B-cell lymphoma/leukemia 10 [KO:K07368]
106596455  B-cell lymphoma/leukemia 10-like [KO:K07368]
106573491  mucosa-associated lymphoid tissue lymphoma translocation protein 1-like [KO:K07369] [EC:3.4.22.-]
106613687  MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog [KO:K07369] [EC:3.4.22.-]
106561168  mucosa-associated lymphoid tissue lymphoma translocation protein 1-like [KO:K07369] [EC:3.4.22.-]
106585741  mucosa-associated lymphoid tissue lymphoma translocation protein 1-like [KO:K07369] [EC:3.4.22.-]
106585388  mucosa-associated lymphoid tissue lymphoma translocation protein 1-like [KO:K07369] [EC:3.4.22.-]
106569473  caspase-8-like [KO:K04398] [EC:3.4.22.61]
106586254  caspase-8-like [KO:K04398] [EC:3.4.22.61]
106582462  caspase-8-like [KO:K04398] [EC:3.4.22.61]
106572992  NF-kappa-B essential modulator-like [KO:K07210]
106590733  ikbkg; inhibitor of nuclear factor kappa B kinase subunit gamma [KO:K07210]
106592447  NF-kappa-B essential modulator-like [KO:K07210]
106580426  ikbkb; inhibitor of nuclear factor kappa B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
106601178  IKBA; NF-kappa-B inhibitor alpha-like [KO:K04734]
106607598  IKBA; NF-kappa-B inhibitor alpha-like [KO:K04734]
106611175  IKBA; NF-kappa-B inhibitor alpha-like [KO:K04734]
106571222  IKBA; NF-kappa-B inhibitor alpha-like [KO:K04734]
106604768  nuclear factor NF-kappa-B p105 subunit-like [KO:K02580]
106611703  nuclear factor NF-kappa-B p105 subunit-like [KO:K02580]
100136457  tnf-alpha-1; tumor necrosis factor alpha-1 precursor [KO:K03156]
100136458  tnf-alpha-2; tumor necrosis factor alpha-2 precursor [KO:K03156]
100136509  tumor necrosis factor alpha [KO:K03156]
106589058  tumor necrosis factor-like [KO:K03156]
106570581  IL6; interleukin-6 [KO:K05405]
106588787  interleukin-6-like [KO:K05405]
106609456  mitogen-activated protein kinase 11-like [KO:K04441] [EC:2.7.11.24]
106609457  MK12; mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
106561402  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
106566975  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
106566983  mitogen-activated protein kinase 14A [KO:K04441] [EC:2.7.11.24]
106573286  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
106572737  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
106572761  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
106566105  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
106566106  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
106576243  MK12; mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
106576244  mitogen-activated protein kinase 11-like [KO:K04441] [EC:2.7.11.24]
100137046  p38b; mitogen activated protein kinase p38b [KO:K04441] [EC:2.7.11.24]
100196619  mk13; Mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
100136932  p38a; mitogen activated protein kinase p38a [KO:K04441] [EC:2.7.11.24]
106604288  mapk8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
106560362  mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
106604910  mitogen-activated protein kinase 9-like [KO:K04440] [EC:2.7.11.24]
106568502  mapk10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
106576863  mitogen-activated protein kinase 8-like [KO:K04440] [EC:2.7.11.24]
106579004  mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
106563760  mitogen-activated protein kinase 9-like [KO:K04440] [EC:2.7.11.24]
106589346  mitogen-activated protein kinase 8-like [KO:K04440] [EC:2.7.11.24]
106600411  jun; Jun proto-oncogene, AP-1 transcription factor subunit [KO:K04448]
106613963  JUN; transcription factor AP-1-like [KO:K04448]
106569413  transcription factor AP-1-like [KO:K04448]
106568560  transcription factor AP-1-like [KO:K04448]
106584280  JUN; transcription factor AP-1-like [KO:K04448]
106572830  transcription factor AP-1-like [KO:K04448]
106602828  cblb; Cbl proto-oncogene B [KO:K22517] [EC:2.3.2.27]
106608748  high affinity immunoglobulin epsilon receptor subunit gamma-like [KO:K07983]
106569423  FCERG; high affinity immunoglobulin epsilon receptor subunit gamma-like [KO:K07983]
106577663  FCERG; high affinity immunoglobulin epsilon receptor subunit gamma-like [KO:K07983]
106573404  CD209 antigen-like protein A [KO:K06563]
100286644  c209a; CD209 antigen-like protein A [KO:K06563]
106610425  CD209 antigen-like protein C [KO:K06563]
106567565  rho guanine nucleotide exchange factor 12-like [KO:K07532]
106603740  rho guanine nucleotide exchange factor 12-like [KO:K07532]
106566794  RHOA; transforming protein RhoA-like [KO:K04513]
106566835  transforming protein RhoA-like [KO:K04513]
106572042  RHOA; transforming protein RhoA-like [KO:K04513]
106565140  RHOA; transforming protein RhoA-like [KO:K04513]
106572261  RHOA; transforming protein RhoA [KO:K04513]
106572962  ras-like GTP-binding protein O-RHO [KO:K04513]
106582735  RHOC; rho-related GTP-binding protein RhoC [KO:K04513]
106592002  RHOA; transforming protein RhoA-like [KO:K04513]
106583462  RHOA; transforming protein RhoA-like [KO:K04513]
100380347  pak3; Serine/threonine-protein kinase PAK 3 [KO:K04409] [EC:2.7.11.1]
106612881  serine/threonine-protein kinase PAK 1-like [KO:K04409] [EC:2.7.11.1]
106603285  kinase suppressor of Ras 1-like [KO:K14958]
106613092  kinase suppressor of Ras 1-like [KO:K14958]
106581250  Galectin-9; kinase suppressor of Ras 1-like [KO:K14958]
106599391  serine/threonine-protein kinase PLK3-like [KO:K08862] [EC:2.7.11.21]
106569079  serine/threonine-protein kinase PLK3-like [KO:K08862] [EC:2.7.11.21]
106565074  proto-oncogene tyrosine-protein kinase Src-like [KO:K05704] [EC:2.7.10.2]
106572626  proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
106567112  proto-oncogene tyrosine-protein kinase Src-like [KO:K05704] [EC:2.7.10.2]
106583686  proto-oncogene tyrosine-protein kinase Src-like [KO:K05704] [EC:2.7.10.2]
106565715  inhibitor of nuclear factor kappa-B kinase subunit epsilon-like [KO:K07211] [EC:2.7.11.10]
100136558  STAT1; signal transducer and activator of transcription 1 alpha [KO:K11220]
106586142  signal transducer and activator of transcription 1-alpha/beta-like [KO:K11220]
106590411  interferon regulatory factor 8-like [KO:K04693]
100380435  irf9; interferon regulatory factor 9 [KO:K04693]
100270812  stat2; signal transducer and activator of transcription 2 [KO:K11221]
100195864  il17d; interleukin 17D [KO:K05492]
106562387  ubiquitin carboxyl-terminal hydrolase CYLD-like [KO:K08601] [EC:3.4.19.12]
106565781  ubiquitin carboxyl-terminal hydrolase CYLD-like [KO:K08601] [EC:3.4.19.12]
106560416  ubiquitin carboxyl-terminal hydrolase CYLD-like [KO:K08601] [EC:3.4.19.12]
106577935  ubiquitin carboxyl-terminal hydrolase CYLD-like [KO:K08601] [EC:3.4.19.12]
106582893  ubiquitin carboxyl-terminal hydrolase CYLD-like [KO:K08601] [EC:3.4.19.12]
100380700  cyld; ubiquitin carboxyl-terminal hydrolase CYLD [KO:K08601] [EC:3.4.19.12]
106577470  B-cell lymphoma 3 protein-like [KO:K09258]
106605697  B-cell lymphoma 3 protein homolog [KO:K09258]
106613702  C-C motif chemokine 17-like [KO:K21083]
106566648  MAPK2; MAP kinase-activated protein kinase 2-like [KO:K04443] [EC:2.7.11.1]
106571864  MAPK2; MAP kinase-activated protein kinase 2-like [KO:K04443] [EC:2.7.11.1]
106583822  MAP kinase-activated protein kinase 2-like [KO:K04443] [EC:2.7.11.1]
106577284  C-type lectin domain family 4 member E-like [KO:K10059]
106602223  C-type lectin domain family 6 member A-like [KO:K10059]
106602773  CD209 antigen-like protein C [KO:K10059]
106605088  CLC4E; C-type lectin domain family 4 member E-like [KO:K10059]
100136446  C209E; C type lectin receptor A [KO:K10059]
100136447  CLC4E; C type lectin receptor B [KO:K10059]
106588291  C-type lectin domain family 4 member E-like [KO:K10059]
106577272  hepatic lectin-like [KO:K10059]
106577273  C-type lectin domain family 4 member E-like [KO:K10059]
106588482  C-type lectin domain family 4 member E-like [KO:K10059]
106610411  C-type lectin domain family 4 member E-like [KO:K10059]
106598808  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
106568747  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
106572046  pik3cd; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [KO:K00922] [EC:2.7.1.153]
106581359  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like [KO:K00922] [EC:2.7.1.153]
106613931  pik3ca; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [KO:K00922] [EC:2.7.1.153]
106613172  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like [KO:K00922] [EC:2.7.1.153]
106600405  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
106567700  phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
106599005  phosphatidylinositol 3-kinase regulatory subunit beta-like [KO:K02649]
106560529  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
106613635  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
106569403  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
106568949  phosphatidylinositol 3-kinase regulatory subunit beta-like [KO:K02649]
106573900  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
106563018  phosphatidylinositol 3-kinase regulatory subunit alpha-like [KO:K02649]
106584012  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
106587034  phosphatidylinositol 3-kinase regulatory subunit alpha-like [KO:K02649]
106582637  RAC-alpha serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
106585772  RAC-gamma serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
106602915  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
106607890  RAC-alpha serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
106610858  RAC-alpha serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
106564869  RAC-gamma serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
106613111  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
106581334  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
106571474  RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100194605  akt2; v-akt murine thymoma viral oncogene homolog 2 [KO:K04456] [EC:2.7.11.1]
106589689  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
106609861  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
106597239  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
106597562  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
106597420  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
106593772  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
106597741  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
106597260  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
106597762  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
106597621  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
106594600  mdm2; MDM2 proto-oncogene [KO:K06643] [EC:2.3.2.27]
106597585  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
100136548  irf-1; interferon regulatory factor 1 [KO:K09444]
100846966  irf1; interferon regulatory factor 1 [KO:K09444]
100846970  irf1-2; interferon regulatory factor 1 isoform 2 [KO:K09444]
Compound
C00027  Hydrogen peroxide
C00076  Calcium cation
C00159  D-Mannose
C00165  Diacylglycerol
C00584  Prostaglandin E2
C00965  1,3-beta-D-Glucan
C01019  L-Fucose
C01245  D-myo-Inositol 1,4,5-trisphosphate
C16844  Hydroxyl radical
C21790  Mycobacterial trehalose dimycolate
C21791  Rhodocytin
G13115  Mannose-capped lipoarabinomannan
Reference
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Reference
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  Journal
Front Immunol 5:288 (2014)
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Reference
PMID:21924922
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Reference
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Front Immunol 3:286 (2012)
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Reference
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  Title
Regulation of C-Type Lectin Receptor-Mediated Antifungal Immunity.
  Journal
Front Immunol 9:123 (2018)
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Reference
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  Title
C-type lectins: their network and roles in pathogen recognition and immunity.
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Reference
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Reference
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  Title
A new path to IL-1beta production controlled by caspase-8.
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Nat Immunol 13:211-2 (2012)
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Reference
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Immunomodulation of Fungal beta-Glucan in Host Defense Signaling by Dectin-1.
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Biomol Ther (Seoul) 20:433-45 (2012)
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Calcineurin-NFAT signalling in myeloid leucocytes: new prospects and pitfalls in immunosuppressive therapy.
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Reference
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Reference
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Reference
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  Title
Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKepsilon- and CYLD-dependent Bcl3 activation.
  Journal
Nat Commun 5:3898 (2014)
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Reference
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Reference
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KO pathway
ko04625   
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