KEGG   PATHWAY: ssx00630
Entry
ssx00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces sp. SirexAA-E
Class
Metabolism; Carbohydrate metabolism
Pathway map
ssx00630  Glyoxylate and dicarboxylate metabolism
ssx00630

Module
ssx_M00621  Glycine cleavage system [PATH:ssx00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces sp. SirexAA-E [GN:ssx]
Gene
SACTE_3012  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
SACTE_5438  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
SACTE_5651  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
SACTE_5472  malate synthase A [KO:K01638] [EC:2.3.3.9]
SACTE_4083  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SACTE_2172  citrate synthase I [KO:K01647] [EC:2.3.3.1]
SACTE_3829  Citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
SACTE_4999  DNA binding domain protein, excisionase family [KO:K01647] [EC:2.3.3.1]
SACTE_5000  Citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
SACTE_6005  2-methylcitrate synthase/citrate synthase II [KO:K01647] [EC:2.3.3.1]
SACTE_5220  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
SACTE_2544  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACTE_4591  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACTE_2706  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACTE_5357  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACTE_5895  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACTE_4590  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
SACTE_5659  methylmalonyl-CoA mutase, large subunit [KO:K14447] [EC:5.4.99.63]
SACTE_4181  Carbamoyl-phosphate synthase L chain ATP-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
SACTE_6342  Carbamoyl-phosphate synthase L chain ATP-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
SACTE_4186  carboxyl transferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
SACTE_4185  conserved hypothetical protein [KO:K27095]
SACTE_4123  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
SACTE_5564  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
SACTE_5575  Methylaspartate mutase [KO:K19268] [EC:5.4.99.1]
SACTE_5574  conserved hypothetical protein [KO:K01846] [EC:5.4.99.1]
SACTE_2401  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
SACTE_0425  Catalase [KO:K03781] [EC:1.11.1.6]
SACTE_4439  Catalase [KO:K03781] [EC:1.11.1.6]
SACTE_6051  Catalase [KO:K03781] [EC:1.11.1.6]
SACTE_5446  Catalase [KO:K03781] [EC:1.11.1.6]
SACTE_3760  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
SACTE_1619  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
SACTE_1629  Glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
SACTE_1676  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
SACTE_1034  Glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
SACTE_4669  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SACTE_4538  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SACTE_4559  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SACTE_0800  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
SACTE_4671  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
SACTE_1604  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SACTE_4670  glycine cleavage system H protein [KO:K02437]
SACTE_5443  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
SACTE_5448  Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
SACTE_5447  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
SACTE_5641  glycerate kinase [KO:K00865] [EC:2.7.1.165]
SACTE_3460  isocitrate dehydrogenase family protein [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
SACTE_1788  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SACTE_6020  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SACTE_4509  2-oxoglutarate dehydrogenase, E1 subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
SACTE_0283  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
SACTE_0282  4Fe-4S ferredoxin iron-sulfur binding domain protein [KO:K00124]
SACTE_3842  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ssx00010  Glycolysis / Gluconeogenesis
ssx00020  Citrate cycle (TCA cycle)
ssx00030  Pentose phosphate pathway
ssx00053  Ascorbate and aldarate metabolism
ssx00071  Fatty acid degradation
ssx00230  Purine metabolism
ssx00250  Alanine, aspartate and glutamate metabolism
ssx00260  Glycine, serine and threonine metabolism
ssx00620  Pyruvate metabolism
ssx00750  Vitamin B6 metabolism
ssx00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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