KEGG ORTHOLOGY: K04387

ORTHOLOGY: K04387

Entry

K04387                      KO

Symbol

IL1R2, CD121b

Name

interleukin 1 receptor type II

Pathway

map04060

Cytokine-cytokine receptor interaction

map04640

Hematopoietic cell lineage

map05146

Amoebiasis

map05166

Human T-cell leukemia virus 1 infection

map05202

Transcriptional misregulation in cancer

map05215

Prostate cancer

map05418

Fluid shear stress and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04387  IL1R2, CD121b; interleukin 1 receptor type II
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04387  IL1R2, CD121b; interleukin 1 receptor type II
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K04387  IL1R2, CD121b; interleukin 1 receptor type II
  09162 Cancer: specific types
   05215 Prostate cancer
    K04387  IL1R2, CD121b; interleukin 1 receptor type II
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04387  IL1R2, CD121b; interleukin 1 receptor type II
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K04387  IL1R2, CD121b; interleukin 1 receptor type II
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K04387  IL1R2, CD121b; interleukin 1 receptor type II
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K04387  IL1R2, CD121b; interleukin 1 receptor type II
   04090 CD molecules
    K04387  IL1R2, CD121b; interleukin 1 receptor type II
Cytokine receptors [BR:ko04050]
Interleukin receptor families
  IL1 receptor family
   K04387  IL1R2, CD121b; interleukin 1 receptor type II
CD molecules [BR:ko04090]
Proteins
  K04387  CD121b, IL1R2; interleukin 1 receptor, type II

Other DBs

GO:

0004910

Genes

HSA:	7850(IL1R2)

PTR:	470455(IL1R2)

PPS:	100972054(IL1R2)

GGO:	101132361(IL1R2)

PON:	100440034(IL1R2)

PPYG:

129030561(IL1R2)

NLE:	100586097(IL1R2)

HMH:	116483129(IL1R2)

SSYN:

129462554(IL1R2)

MCC:	711638(IL1R2)

MCF:	102143926(IL1R2)

MTHB:

126934233

MNI:	105490122(IL1R2)

CSAB:

103241146(IL1R2)

CATY:

105583644(IL1R2)

PANU:

101003327(IL1R2)

TGE:	112604767(IL1R2)

MLEU:

105531619(IL1R2)

RRO:	104680312(IL1R2)

RBB:	108524092(IL1R2)

TFN:	117062284(IL1R2)

PTEH:

111542170(IL1R2)

CANG:

105522166(IL1R2)

CJC:	100393582(IL1R2)

SBQ:	101032260(IL1R2)

CIMI:

108317430(IL1R2)

ANAN:

105730382(IL1R2)

CSYR:

103259326(IL1R2)

MMUR:

105857843(IL1R2)

LCAT:

123637265(IL1R2)

PCOQ:

105808352(IL1R2)

OGA:	100959451(IL1R2)

MMU:	16178(Il1r2)

MCAL:

110302131(Il1r2)

MPAH:

110322453(Il1r2)

RNO:	117022(Il1r2)

MCOC:

116088347(Il1r2)

ANU:	117722520(Il1r2)

ASYL:

127692612(Il1r2)

MUN:	110561822(Il1r2)

CGE:	100759030(Il1r2)

MAUA:

101842359(Il1r2)

PROB:

127236720(Il1r2)

PLEU:

114690861(Il1r2)

MORG:

121450964(Il1r2)

MFOT:

126496982

AAMP:

119823882(Il1r2)

NGI:	103744179(Il1r2)

HGL:	101710536(Il1r2)

CPOC:

100723930(Il1r2)

CCAN:

109682276(Il1r2)

DORD:

105988217(Il1r2)

DSP:	122121279(Il1r2)

DMER:

138804172(Il1r2)

PLOP:

125356835(Il1r2)

NCAR:

124963189

MMMA:

107158537(Il1r2)

ITI:	101960146(Il1r2)

OCU:

100344048

OPI:	101530141(IL1R2)

TUP:	102491995(IL1R2)

GVR:	103610385(IL1R2)

CFA:	481330(IL1R2)

CLUD:

112669967(IL1R2)

VVP:	112915145(IL1R2)

VLG:	121490471(IL1R2)

NPO:	129511797(IL1R2)

AML:	100475938(IL1R2)

UMR:	103670643(IL1R2)

UAH:	113247309(IL1R2)

UAR:	123776050(IL1R2)

ELK:

111155901

LLV:

125109725

MPUF:

101694390(IL1R2)

MNP:	132022606(IL1R2)

MLK:	131807723(IL1R2)

NVS:	122916394(IL1R2)

ORO:	101381470(IL1R2)

EJU:	114209782(IL1R2)

ZCA:	113937488(IL1R2)

MLX:	118008268(IL1R2)

NSU:	110572040(IL1R2)

LWW:	102741288(IL1R2)

FCA:	101080961(IL1R2)

PYU:	121016437(IL1R2)

PCOO:

112868843(IL1R2)

PBG:	122496691(IL1R2)

PVIV:

125161499(IL1R2)

LRUF:

124503236

LGF:	123580636(IL1R2)

AJU:

106968746

PTG:	102959004(IL1R2)

PPAD:

109254568(IL1R2)

PUC:

125936912

PLEZ:

122215929(IL1R2)

HHV:	120245901(IL1R2)

BTA:	515700(IL1R2)

BOM:	102271891(IL1R2)

BIU:	109565866(IL1R2)

BBUB:

102401594(IL1R2)

BBIS:

104980850(IL1R2)

CHX:	102186601(IL1R2)

OAS:	101103308(IL1R2)

BTAX:

128056702(IL1R2)

CSUM:

138083216(IL1R2)

ODA:	120883611(IL1R2)

CCAD:

122441437(IL1R2)

MREE:

136164559(IL1R2)

OVR:	110151080(IL1R2)

MBEZ:

129539365(IL1R2)

SSC:	100628112(IL1R2)

CFR:	102505984(IL1R2)

CBAI:

105072216(IL1R2)

CDK:	105099111(IL1R2)

VPC:	102540563(IL1R2)

BACU:

102999629(IL1R2)

BMUS:

118905619(IL1R2)

LVE:

103069948

OOR:	101276960(IL1R2)

LALB:

132531696(IL1R2)

GMF:	115843096(IL1R2)

DDP:	132435558(IL1R2)

DLE:	111187494(IL1R2)

PCAD:

102973842(IL1R2)

PSIU:

116763888(IL1R2)

PPHC:

136134048(IL1R2)

NASI:

112399068(IL1R2)

ECB:	100033831(IL1R2)

EPZ:	103559218(IL1R2)

EAI:	106839396(IL1R2)

MYB:	102239307(IL1R2)

MYD:	102774276(IL1R2)

MMYO:

118679031(IL1R2)

MLF:	102434854(IL1R2)

MDT:	132212979(IL1R2)

MYUM:

139019531(IL1R2)

PKL:	118727965(IL1R2)

EFUS:

103296806(IL1R2)

MNA:	107532703(IL1R2)

DRO:	112315222(IL1R2)

SHON:

118994652(IL1R2)

AJM:	119051894(IL1R2)

PDIC:

114500036(IL1R2)

PHAS:

123811723(IL1R2)

MMF:	118631028(IL1R2)

PPAM:

129074243(IL1R2)

HAI:	109395468(IL1R2)

RFQ:	117032649(IL1R2)

PALE:

102884188(IL1R2)

PGIG:

120584447(IL1R2)

PVP:	105298726(IL1R2)

RAY:	107498113(IL1R2)

MJV:	108404710(IL1R2)

TOD:	119259925(IL1R2)

SARA:

101536971(IL1R2)

SFUM:

130035789(IL1R2)

SETR:

126024495(IL1R2)

LAV:	100667125(IL1R2)

TMU:

101344340

ETF:	101661183(IL1R2)

DNM:	101446780(IL1R2)

MDO:	100017640(IL1R2)

GAS:	123241762(IL1R2)

SHR:	100913252(IL1R2)

AFZ:

127553550

PCW:	110209394(IL1R2)

TVP:	118848556(IL1R2)

PBRV:

138171144(IL1R2)

OAA:	100084042(IL1R2)

TACU:

119921976(IL1R2)

GGA:	418715(IL1R2)

PCOC:

116236486

MGP:	100542672(IL1R2)

CJO:	107306854(IL1R2)

TPAI:

128071809

LMUT:

125699717

NMEL:

110406769(IL1R2)

APLA:

101793878

ACYG:

106041632(IL1R2)

CATA:

118253537(IL1R2)

AFUL:

116500711

TGU:	100230419(IL1R2)

LSR:	110474960(IL1R2)

SCAN:

103812645(IL1R2)

PMOA:

120504583(IL1R2)

OTC:	121343208(IL1R2)

PRUF:

121354093(IL1R2)

ATRC:

139591765(IL1R2)

GFR:	102034720(IL1R2)

FAB:	101815893(IL1R2)

OMA:	130251047(IL1R2)

PHI:

102109460

PMAJ:

107213480(IL1R2)

CCAE:

111922338(IL1R2)

CCW:	104686062(IL1R2)

CBRC:

103617599

ACOE:

138105574(IL1R2)

ETL:	114069084(IL1R2)

ZAB:	102065047(IL1R2)

ZLE:

135446547

ACHL:

103809622(IL1R2)

SVG:	106863663(IL1R2)

MMEA:

130578639(IL1R2)

HRT:	120748764(IL1R2)

SATI:

136357959(IL1R2)

CCIC:

134041323

FPG:	101912185(IL1R2)

FCH:	102059985(IL1R2)

CCRI:

104163028

NNT:

104408149

SHAB:

115603666(IL1R2)

ACUN:

113486165(IL1R2)

TALA:

104360921(IL1R2)

ACHC:

115334518(IL1R2)

HALD:

104317674(IL1R2)

HLE:	104836922(IL1R2)

AGEN:

126053031

HHAR:

128135062(IL1R2)

GCL:

127013131

CSTI:

104561487(IL1R2)

LDI:

104353284

MNB:	103776773(IL1R2)

DPUB:

104310044(IL1R2)

PPUS:

135175465

AVIT:

104276773

BRHI:

104492412 104496674

EGZ:	104126402(IL1R2)

NNI:	104019397(IL1R2)

PCRI:

104029053

PADL:

103918872(IL1R2)

AFOR:

103896327(IL1R2)

FGA:

104077021

GSTE:

104260488

CBOY:

140646189(IL1R2)

CLV:

CNIC:

MUI:

PGUU:

PLET:

EHS:

CMAC:

104485106(IL1R2)

CUCA:

104056690(IL1R2)

TEO:

104379569

BREG:

104632102 104643931

OHA:	104329457(IL1R2)

ACAR:

104530596

CPEA:

104389001(IL1R2)

CVF:	104284748(IL1R2)

RTD:	128917442(IL1R2)

CRID:

134517612(IL1R2)

AAM:	106493981(IL1R2)

AROW:

112966420

NPD:	112954962(IL1R2)

TGT:	104568661(IL1R2)

DNE:	112984942(IL1R2)

SCAM:

104138638(IL1R2)

ASN:

102377367

AMJ:	102558781(IL1R2)

CPOO:

109306228

GGN:

109303345

PSS:	102447027(IL1R2)

CMY:	102937756(IL1R2)

CCAY:

125639825(IL1R2)

DCC:	119849773(IL1R2)

CPIC:

101942576(IL1R2)

TST:	117870719(IL1R2)

CABI:

116832866(IL1R2)

MRV:	120397027(IL1R2)

ACS:	100553195(il1r2)

ASAO:

132771570(IL1R2)

PVT:	110090149(IL1R2)

SUND:

121924889(IL1R2)

PBI:	103053232(IL1R2)

PMUR:

107286533

CTIG:

120313675(IL1R2)

TSR:

106549293

PGUT:

117667392

PCAE:

139316732

APRI:

131199690(IL1R2)

PTEX:

113440770

NSS:	113411626(IL1R2)

VKO:	123025393(IL1R2)

PMUA:

114596486(IL1R2)

PRAF:

128411793(IL1R2)

ZVI:

118084997

HCG:	128349750(IL1R2)

GJA:

107120036

STOW:

125431339(IL1R2)

EMC:

129326206

XLA:	108708406(il1r2.L)

XTR:	548430(il1r2)

NPR:	108785107(IL1R2)

RTEM:

120926476(IL1R2)

ACAT:

141127901(IL1R2)

BBUF:

120993465

BGAR:

122932735

DTC:	141101393(IL1R2)

PWL:	138250049(IL1R2)

MUO:

GSH:

SRX:

SANH:

SGH:

CAUA:

IPU:

PHYP:

TFD:

AMEX:

EEE:

CHAR:

SPIL:

TRU:	101071789(il1r2)

TFS:

130529538

TNG:	GSTEN00029185G001

LCO:

104918238

NCC:	104951249 104954165

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

SCHU:

CUD:

SPUL:

LMIX:

ALAT:

ASTR:

MZE:	101475796 101484472 112430070

ONL:	100702124 102076609 112844175

OAU:	116314762 116314763

OLA:

101157738

OML:

112154799

CSAI:

133446338

XMA:	102224450(il1r2) 111608367

XCO:

114148816

XHE:	116723709(il1r2)

PRET:

103478386(il1r2)

PFOR:

103134844(il1r2)

PLAI:

106951386(il1r2)

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:	107381673 107389641

KMR:

ALIM:

NWH:

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

POV:

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:	108897018 108897084

SDU:

111218441

SLAL:

111650527

XGL:

120801066

HCQ:	109522273(il1r2)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

ENY:

MALB:

109974022(il1r2)

BSPL:

114847515

SJO:

128368099

SSCO:

133993184

GMH:	115532949(il1r2)

SASA:

100270808(il1r2)

STRU:

115161016

OTW:

112239371

OMY:	100136032(il-1rii)

OGO:

ONE:

OKI:

OKE:

OMM:

OCLA:

SALP:

SNH:

CCLU:

OEP:

SFM:	108926886(il1r2)

PKI:

AANG:

AROT:

CCOG:

LOC:	102698656(il1r2)

PSPA:

121320454

ARUT:

117405634

LCM:	102361020(IL1R2)

CMK:

103172482

PMAX:

117341380

» show all

Reference

PMID:1833184

Authors

McMahan CJ, Slack JL, Mosley B, Cosman D, Lupton SD, Brunton LL, Grubin CE, Wignall JM, Jenkins NA, Brannan CI, et al.

Title

A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

Journal

EMBO J 10:2821-32 (1991)
DOI:10.1002/j.1460-2075.1991.tb07831.x

Sequence

[hsa:7850]

Reference

PMID:9862719

Authors

Lang D, Knop J, Wesche H, Raffetseder U, Kurrle R, Boraschi D, Martin MU.

Title

The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness.

Journal

J Immunol 161:6871-7 (1998)

LinkDB

DBGET integrated database retrieval system