Homo sapiens (human): 7850
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Entry
7850 CDS
T01001
Symbol
IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB
Name
(RefSeq) interleukin 1 receptor type 2
KO
K04387
interleukin 1 receptor type II
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04640
Hematopoietic cell lineage
hsa05146
Amoebiasis
hsa05166
Human T-cell leukemia virus 1 infection
hsa05202
Transcriptional misregulation in cancer
hsa05215
Prostate cancer
hsa05418
Fluid shear stress and atherosclerosis
Network
nt06240
Transcription (cancer)
nt06272
Prostate cancer
Element
N00128
TMPRSS2-ERG fusion to transcriptional activation
Drug target
Anakinra:
D02934
<US>
Isunakinra:
D11759
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
7850 (IL1R2)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
7850 (IL1R2)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
7850 (IL1R2)
09162 Cancer: specific types
05215 Prostate cancer
7850 (IL1R2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
7850 (IL1R2)
09174 Infectious disease: parasitic
05146 Amoebiasis
7850 (IL1R2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
7850 (IL1R2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04050 Cytokine receptors [BR:
hsa04050
]
7850 (IL1R2)
04090 CD molecules [BR:
hsa04090
]
7850 (IL1R2)
Cytokine receptors [BR:
hsa04050
]
Interleukin receptor families
IL1 receptor family
7850 (IL1R2)
CD molecules [BR:
hsa04090
]
Proteins
7850 (IL1R2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ig
Ig_3
I-set
Ig_2
V-set
Ig_6
Izumo-Ig
Sp38
LPD11
Motif
Other DBs
NCBI-GeneID:
7850
NCBI-ProteinID:
NP_004624
OMIM:
147811
HGNC:
5994
Ensembl:
ENSG00000115590
UniProt:
P27930
Structure
PDB
LinkDB
All DBs
Position
2:101991960..102028544
Genome browser
AA seq
398 aa
AA seq
DB search
MLRLYVLVMGVSAFTLQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWAS
VSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMS
IELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDN
EKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVII
SPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSE
NNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASSTFSWGIVLAPLSLA
FLVLGGIWMHRRCKHRTGKADGLTVLWPHHQDFQSYPK
NT seq
1197 nt
NT seq
+upstream
nt +downstream
nt
atgttgcgcttgtacgtgttggtaatgggagtttctgccttcacccttcagcctgcggca
cacacaggggctgccagaagctgccggtttcgtgggaggcattacaagcgggagttcagg
ctggaaggggagcctgtagccctgaggtgcccccaggtgccctactggttgtgggcctct
gtcagcccccgcatcaacctgacatggcataaaaatgactctgctaggacggtcccagga
gaagaagagacacggatgtgggcccaggacggtgctctgtggcttctgccagccttgcag
gaggactctggcacctacgtctgcactactagaaatgcttcttactgtgacaaaatgtcc
attgagctcagagtttttgagaatacagatgctttcctgccgttcatctcatacccgcaa
attttaaccttgtcaacctctggggtattagtatgccctgacctgagtgaattcacccgt
gacaaaactgacgtgaagattcaatggtacaaggattctcttcttttggataaagacaat
gagaaatttctaagtgtgagggggaccactcacttactcgtacacgatgtggccctggaa
gatgctggctattaccgctgtgtcctgacatttgcccatgaaggccagcaatacaacatc
actaggagtattgagctacgcatcaagaaaaaaaaagaagagaccattcctgtgatcatt
tcccccctcaagaccatatcagcttctctggggtcaagactgacaatcccgtgtaaggtg
tttctgggaaccggcacacccttaaccaccatgctgtggtggacggccaatgacacccac
atagagagcgcctacccgggaggccgcgtgaccgaggggccacgccaggaatattcagaa
aataatgagaactacattgaagtgccattgatttttgatcctgtcacaagagaggatttg
cacatggattttaaatgtgttgtccataataccctgagttttcagacactacgcaccaca
gtcaaggaagcctcctccacgttctcctggggcattgtgctggccccactttcactggcc
ttcttggttttggggggaatatggatgcacagacggtgcaaacacagaactggaaaagca
gatggtctgactgtgctatggcctcatcatcaagactttcaatcctatcccaagtga
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