KEGG   ORTHOLOGY: K05726
Entry
K05726                      KO                                     

Name
BCAR1, CAS
Definition
breast cancer anti-estrogen resistance 1
Pathway
ko04015  Rap1 signaling pathway
ko04062  Chemokine signaling pathway
ko04510  Focal adhesion
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko04935  Growth hormone synthesis, secretion and action
ko05100  Bacterial invasion of epithelial cells
ko05131  Shigellosis
ko05135  Yersinia infection
ko05163  Human cytomegalovirus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
   04062 Chemokine signaling pathway
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
   05135 Yersinia infection
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
   05100 Bacterial invasion of epithelial cells
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
Genes
HSA: 9564(BCAR1)
PTR: 454246(BCAR1)
PPS: 100980143(BCAR1)
GGO: 101132653(BCAR1)
PON: 103889518(BCAR1)
NLE: 100598535(BCAR1)
MCC: 713965(BCAR1)
MCF: 102114845(BCAR1)
CSAB: 103233309(BCAR1)
RRO: 104677838(BCAR1)
RBB: 108527422(BCAR1)
CJC: 100391559(BCAR1)
SBQ: 101041293(BCAR1)
MMU: 12927(Bcar1)
MCAL: 110299902(Bcar1)
MPAH: 110337447(Bcar1)
RNO: 25414(Bcar1)
MUN: 110554744(Bcar1)
CGE: 100768861(Bcar1)
NGI: 103725688(Bcar1)
HGL: 101709701(Bcar1)
CCAN: 109684025(Bcar1)
OCU: 100350323(BCAR1)
TUP: 102488824(BCAR1)
CFA: 479648(BCAR1)
VVP: 112915672(BCAR1)
AML: 100479448(BCAR1)
UMR: 103662115(BCAR1)
UAH: 113252495(BCAR1)
ORO: 101364349(BCAR1)
ELK: 111152853
FCA: 101096625(BCAR1)
PTG: 102961947(BCAR1)
PPAD: 109245694(BCAR1)
AJU: 106989704(BCAR1)
BTA: 527550(BCAR1)
BOM: 102286652(BCAR1)
BIU: 109572528(BCAR1)
BBUB: 102391781(BCAR1)
CHX: 102176451(BCAR1)
OAS: 101117693(BCAR1) 114112432
SSC: 100621541(BCAR1)
CFR: 102522119(BCAR1)
CDK: 105085072(BCAR1)
BACU: 102999909(BCAR1)
LVE: 103077564(BCAR1)
OOR: 101286283(BCAR1)
DLE: 111179506(BCAR1)
PCAD: 102974736(BCAR1)
ECB: 100068908(BCAR1)
EPZ: 103553038(BCAR1)
EAI: 106835699(BCAR1)
MYB: 102256265(BCAR1)
MYD: 102751761(BCAR1)
MNA: 107524660(BCAR1)
HAI: 109384807(BCAR1)
DRO: 112300743(BCAR1)
PALE: 102897097(BCAR1)
RAY: 107502656(BCAR1)
MJV: 108396170(BCAR1)
LAV: 100675124(BCAR1)
TMU: 101346861
PCW: 110192462(BCAR1)
OAA: 100085802(BCAR1)
GGA: 415691(BCAR1)
MGP: 100543321 104913032(BCAR1)
CJO: 107319194(BCAR1)
NMEL: 110404454(BCAR1)
APLA: 101792603(BCAR1)
ACYG: 106043124(BCAR1)
TGU: 100231478(BCAR1)
LSR: 110472998(BCAR1)
SCAN: 103816661(BCAR1)
GFR: 102041223(BCAR1)
FAB: 101822200(BCAR1)
PHI: 102099890(BCAR1)
PMAJ: 107209875(BCAR1)
CCAE: 111934540(BCAR1)
CCW: 104687562(BCAR1)
ETL: 114069815(BCAR1)
FPG: 101919872(BCAR1)
FCH: 102047594(BCAR1)
CLV: 102090770(BCAR1)
EGZ: 104130282(BCAR1)
NNI: 104016382(BCAR1)
ACUN: 113484549(BCAR1)
AAM: 106490061(BCAR1)
ASN: 102387422(BCAR1)
AMJ: 102565268(BCAR1)
CMY: 102938416(BCAR1)
CPIC: 101937536(BCAR1)
PVT: 110081315(BCAR1)
PBI: 103054416(BCAR1)
PMUR: 107287376(BCAR1)
TSR: 106539030(BCAR1)
PMUA: 114601800(BCAR1)
GJA: 107107898(BCAR1)
XLA: 108715363(bcar1.S) 398756(bcar1.L)
XTR: 447979(bcar1)
NPR: 108796559(BCAR1)
DRE: 568309(bcar1)
SRX: 107726155(bcar1)
IPU: 108264615(bcar1)
PHYP: 113534477(bcar1)
AMEX: 103028804(bcar1)
EEE: 113573599(bcar1)
LCO: 104939488(bcar1)
NCC: 104967430
MZE: 101473839(bcar1)
ONL: 100705076(bcar1)
OLA: 101167688(bcar1)
XMA: 102230743(bcar1)
XCO: 114157230(bcar1)
PRET: 103465773(bcar1)
CVG: 107096741(bcar1)
NFU: 107389510(bcar1)
KMR: 108246391(bcar1)
ALIM: 106510812
AOCE: 111566681(bcar1)
CSEM: 103379847(bcar1)
POV: 109642993
LCF: 108884593(bcar1)
SDU: 111234832(bcar1)
SLAL: 111647742(bcar1)
HCQ: 109520705
BPEC: 110169470(bcar1)
MALB: 109967267(bcar1)
OTW: 112252351
ELS: 105018442(bcar1)
SFM: 108918978(bcar1) 108933991
PKI: 111851927(bcar1) 111859378
LCM: 102355909 102362517(BCAR1)
CMK: 103176114(bcar1)
RTP: 109925586(bcar1)
BFO: 118417185
SPU: 576962
APLC: 110980128
SKO: 100374152
CRG: 105329588
MYI: 110467508
OBI: 106870453
NVE: 116604372
EPA: 110251985
DGT: 114532660
HMG: 100206888
 » show all
Reference
  Authors
Modzelewska K, Newman LP, Desai R, Keely PJ
  Title
Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas.
  Journal
J Biol Chem 281:37527-35 (2006)
DOI:10.1074/jbc.M604342200
  Sequence
[hsa:9564]
Reference
  Authors
Brinkman A, van der Flier S, Kok EM, Dorssers LC
  Title
BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells.
  Journal
J Natl Cancer Inst 92:112-20 (2000)
DOI:10.1093/jnci/92.2.112
  Sequence
[hsa:9564]
LinkDB

DBGET integrated database retrieval system