KEGG   NETWORK: N00933
Entry
N00933                      Network                                

Name
Escherichia NleA to NLRP3 inflammasome signaling pathway
Definition
NleA -| (NLRP3+PYCARD)
  Expanded
K16041 -| (114548+29108)
Class
nt06139 NLR signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05130  Pathogenic Escherichia coli infection
Disease
H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
H00278  Enteropathogenic Escherichia coli (EPEC) infection
Gene
114548  NLRP3; NLR family pyrin domain containing 3
29108  PYCARD; PYD and CARD domain containing
Perturbant
K16041 (NleA)  nleA; non-LEE-encoded effector NleA
Reference
  Authors
Yen H, Sugimoto N, Tobe T
  Title
Enteropathogenic Escherichia coli Uses NleA to Inhibit NLRP3 Inflammasome Activation.
  Journal
PLoS Pathog 11:e1005121 (2015)
DOI:10.1371/journal.ppat.1005121
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