KEGG   ORTHOLOGY: K16041
Entry
K16041                      KO                                     
Symbol
nleA
Name
non-LEE-encoded effector NleA
Pathway
map05130  Pathogenic Escherichia coli infection
Module
M00542  EHEC/EPEC pathogenicity signature, T3SS and effectors
Network
nt06125  Membrane trafficking (bacteria)
nt06139  NLR signaling (viruses and bacteria)
  Element
N00933  Escherichia NleA to NLRP3 inflammasome signaling pathway
N01290  Escherichia NleA to COPII vesicle formation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K16041  nleA; non-LEE-encoded effector NleA
Genes
ECE: Z6024
ECS: ECs_1812(nleA_espI)
ECF: ECH74115_1807
ETW: ECSP_1702(nleA)
ELX: CDCO157_1740
EOI: ECO111_2959
EOJ: ECO26_3149
EOH: ECO103_0807
ECOO: ECRM13514_2844(nleA)
ECOH: ECRM13516_2757(nleA)
CRO: ROD_03401(espI)
VG: 5580434(PBV4795_ORF83)
 » show all
Reference
  Authors
Gruenheid S, Sekirov I, Thomas NA, Deng W, O'Donnell P, Goode D, Li Y, Frey EA, Brown NF, Metalnikov P, Pawson T, Ashman K, Finlay BB
  Title
Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7.
  Journal
Mol Microbiol 51:1233-49 (2004)
DOI:10.1046/j.1365-2958.2003.03911.x
  Sequence
[cro:ROD_03401]
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