Canis lupus familiaris (dog): 100856745
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Entry
100856745 CDS
T01007
Symbol
HADHA
Name
(RefSeq) trifunctional enzyme subunit alpha, mitochondrial
KO
K07515
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:
4.2.1.17
1.1.1.211
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00062
Fatty acid elongation
cfa00071
Fatty acid degradation
cfa00280
Valine, leucine and isoleucine degradation
cfa00310
Lysine degradation
cfa00380
Tryptophan metabolism
cfa00410
beta-Alanine metabolism
cfa00640
Propanoate metabolism
cfa00650
Butanoate metabolism
cfa01100
Metabolic pathways
cfa01212
Fatty acid metabolism
Module
cfa_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
cfa_M00085
Fatty acid elongation in mitochondria
cfa_M00087
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
100856745 (HADHA)
00650 Butanoate metabolism
100856745 (HADHA)
09103 Lipid metabolism
00062 Fatty acid elongation
100856745 (HADHA)
00071 Fatty acid degradation
100856745 (HADHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
100856745 (HADHA)
00310 Lysine degradation
100856745 (HADHA)
00380 Tryptophan metabolism
100856745 (HADHA)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
100856745 (HADHA)
Enzymes [BR:
cfa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.211 long-chain-3-hydroxyacyl-CoA dehydrogenase
100856745 (HADHA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
100856745 (HADHA)
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Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
3HCDH
ECH_2
Motif
Other DBs
NCBI-GeneID:
100856745
NCBI-ProteinID:
XP_003639634
Ensembl:
ENSCAFG00000004267
VGNC:
49107
UniProt:
A0A8C0RD03
A0A8I3PUE4
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All DBs
Position
17:complement(20202960..20251371)
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AA seq
762 aa
AA seq
DB search
MVASRAIGSLSRATASRMFRCPGYVCRNFTGSSALRSRTHINFGVKGDVAVVRLNSPNSK
VNTLNKELQSEFMEVMNEIWASDQIRSAVLISTKPGCFIAGADINMLASCKTHEEVTRIS
QEGQRMFEKLEKSTKPIVAAISGACLGGGLELAISCQYRIATKDRKTVLGAPEVLLGILP
GAGGTQRLPKMVGLPAAFDMMLTGRNIRADRAKRMGLVDQLVEPLGPGLKPPEERTIEYL
EEVAVNFAKGLSDKKISIKRDKGLVEKLTSYALSIPFVRQQVYKKVEEKVRKQTKGLYPA
PLKIIDVVKTGIEQGNDAGYLSESQKFGELAMTKESKALMGLYHGQVLCKKNKFGAPQKE
VKDLAILGAGLMGAGIAQVSVDKGLKTILKDATLTGLGRGQQQVFKGLNDKVKKKALTSF
ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPGHCVFASNTSALP
INEIAAASKRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLKQGKVIIVVK
DGPGFYTTRCLAPMMSEVLRILQEGVEPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVS
EDLGKAFGERFEGGNIELLKEMVSRGFLGRKSGKGFYIYQEGVKTKNVNSDMDGILASLK
VPPKYGVSSDEDIQYRLVTRFVNEAVLCLQEGILATPTEGDIGAVFGLGFPPCLGGPFRF
VDLYGAQKIVDRLRKFEAAYGKQFTPCQLLIDHANSANKFYQ
NT seq
2289 nt
NT seq
+upstream
nt +downstream
nt
atggtggcctcccgagctataggcagcctcagccgcgccactgcctcccggatgttccgc
tgcccaggttatgtatgccgcaactttacagggtcctctgctctgagatctagaacccat
attaactttggagtcaaaggggatgtggctgttgttcgacttaactcgcccaattcaaag
gtaaatacactgaataaagaactacaatcagaattcatggaagtaatgaatgaaatctgg
gctagtgatcaaatcagaagtgctgtccttatctctacgaagccaggctgctttattgca
ggtgctgacatcaacatgttagcttcttgtaagacccatgaagaggtaacacgaatatca
caggaaggacagagaatgtttgagaaacttgagaagtccacaaagcctattgtggctgcc
atcagtggagcctgcttaggaggaggacttgagcttgccatttcctgccaatatagaata
gcaaccaaagatagaaaaacagtattaggtgcccctgaagtcttgctggggatcttacca
ggagcaggaggcacacaaaggctgcccaaaatggtgggtctgcctgctgcttttgacatg
atgttgactggtagaaacattcgtgcagacagagcaaagagaatgggactggttgaccaa
ttagtggaacccctgggaccaggattaaaacctccagaggaacggacaattgaatactta
gaagaagttgcagttaattttgccaaaggactatctgataagaaaatctccataaagaga
gacaagggattagtagaaaaattgacgtcatatgccctgagtattccttttgtcagacaa
caggtttacaaaaaggtggaagaaaaagtacgaaaacagaccaaaggcctttatcctgca
cctctgaaaataatcgatgtggtaaagactggaattgagcaagggaacgatgctggctat
ctctctgaatctcagaaatttggagagcttgcaatgaccaaagaatcaaaggcgttgatg
ggactttatcatggtcaggtcctgtgtaagaagaataaatttggagctccgcagaaagaa
gtaaaggacctagccattcttggtgcagggctgatgggagccggcattgcccaggtctct
gtggataagggcctgaagaccatacttaaagatgctacgctaaccgggctgggccgagga
cagcagcaggtgttcaaaggattgaatgataaagtgaagaagaaagctctaacatcattt
gaaagggactccatttttagcaacttgactgggcagctcgattaccaaggttttgaaaag
gctgacatggtgattgaagctgtttttgaggacctaagtcttaagcacagagtgctaaaa
gaagtggaagcggtgattccaggtcactgtgtctttgccagtaacacatctgctctccca
atcaatgaaattgctgctgccagcaaaagacctgagaaggtgattggcatgcactacttc
tctcctgtggacaagatgcagctactggagattattacaacagataaaacgtctaaggac
accactgcttcagcggtagctgtcgggctcaagcaggggaaggtcatcattgtggtgaaa
gatggacctggcttctacaccaccaggtgccttgcacccatgatgtctgaagtcctcaga
atcctccaggaaggagttgagcctaagaagctggattcccttaccacaagctttggcttt
cctgtgggtgctgccacactggtcgatgaagttggtgtggatgtagcaaaacatgtatca
gaagatctgggcaaagcctttggggaacggtttgaaggtggaaacatagaactgctgaag
gagatggtgtccaggggcttcctgggtcgcaagtctgggaaaggcttttacatctaccag
gagggtgtgaagactaagaatgtgaattctgacatggatggtattttggcaagtctgaag
gtgccccctaagtatggcgtctcctcggatgaagacatccagtaccgcctggtgacaaga
tttgtgaatgaggccgtcctgtgcctgcaggaagggatcttggccacacccacagaggga
gacatcggagcggtgtttgggcttggctttcccccatgtcttggagggcccttccgcttt
gtggatctgtatggtgctcagaagatagtggaccggctcaggaagtttgaggctgcctat
ggaaaacagttcaccccatgtcagctgctcattgaccacgcgaacagtgctaacaagttc
taccagtga
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