| Entry |
|
|---|
| Name |
Cediranib (USAN/INN) |
|---|
| Formula |
C25H27FN4O3
|
|---|
| Exact mass |
450.2067
|
|---|
| Mol weight |
450.50
|
|---|
| Structure |
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|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03203 VEGFR inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Angiogenesis inhibitor, Receptor tyrosine kinase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01E PROTEIN KINASE INHIBITORS
L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors
L01EK02 Cediranib
D08881 Cediranib (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03203 VEGFR inhibitor
DG01360 Cediranib
D08881 Cediranib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
VEGFR family
VEGFR1 (FLT1)
D08881 Cediranib (USAN/INN)
VEGFR2 (KDR)
D08881 Cediranib (USAN/INN)
VEGFR3 (FLT4)
D08881 Cediranib (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03203 VEGFR inhibitor
DG01360 Cediranib
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 33
1 C8y C 17.5474 -15.6104
2 C8y C 17.5474 -14.2048
3 C8x C 18.7421 -16.3131
4 C8y C 16.2825 -16.3131
5 N5x N 16.2825 -13.5020
6 C8x C 18.7421 -13.5020
7 C8y C 19.9369 -15.6104
8 N5x N 15.0877 -15.6104
9 C8x C 15.0877 -14.2048
10 C8y C 19.9369 -14.2048
11 O2a O 21.2018 -16.3131
12 O2a O 21.2018 -13.5020
13 C1a C 22.3965 -15.6104
14 C1b C 22.3965 -14.2048
15 O2a O 16.3352 -17.7186
16 C8y C 15.0525 -18.3989
17 C8y C 13.8286 -17.6717
18 C8y C 12.6026 -18.3591
19 C8y C 12.5852 -19.7645
20 C8x C 13.8089 -20.4918
21 C8x C 15.0348 -19.8044
22 C8x C 11.2714 -17.9079
23 C8y C 10.4310 -19.0345
24 N4x N 11.2428 -20.1820
25 C1a C 9.0444 -19.0173
26 X F 13.8467 -16.2430
27 C1b C 23.6195 -13.5120
28 C1b C 24.8055 -14.2098
29 N1y N 26.0157 -13.5241
30 C1x C 27.2577 -14.0891
31 C1x C 28.1788 -13.0824
32 C1x C 27.5061 -11.8953
33 C1x C 26.1692 -12.1684
BOND 37
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 5 9 2
9 6 10 2
10 7 11 1
11 10 12 1
12 11 13 1
13 12 14 1
14 7 10 1
15 8 9 1
16 4 15 1
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 16 21 1
24 18 22 1
25 22 23 2
26 23 24 1
27 19 24 1
28 23 25 1
29 17 26 1
30 14 27 1
31 27 28 1
32 28 29 1
33 29 30 1
34 30 31 1
35 31 32 1
36 32 33 1
37 29 33 1
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