Heterocephalus glaber (naked mole rat): 101697163 Help Entry 101697163         CDS       T02812                                  Definition (RefSeq) interferon alpha-4-like   KO K05414   interferon alpha Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04151   PI3K-Akt signaling pathway hgl04217   Necroptosis hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04622   RIG-I-like receptor signaling pathway hgl04623   Cytosolic DNA-sensing pathway hgl04630   JAK-STAT signaling pathway hgl04650   Natural killer cell mediated cytotoxicity hgl05152   Tuberculosis hgl05160   Hepatitis C hgl05161   Hepatitis B hgl05162   Measles hgl05163   Human cytomegalovirus infection hgl05164   Influenza A hgl05165   Human papillomavirus infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05168   Herpes simplex virus 1 infection hgl05169   Epstein-Barr virus infection hgl05170   Human immunodeficiency virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05320   Autoimmune thyroid disease Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101697163    04151 PI3K-Akt signaling pathway     101697163   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101697163  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101697163  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101697163    04621 NOD-like receptor signaling pathway     101697163    04622 RIG-I-like receptor signaling pathway     101697163    04623 Cytosolic DNA-sensing pathway     101697163    04650 Natural killer cell mediated cytotoxicity     101697163  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101697163   09163 Immune disease    05320 Autoimmune thyroid disease     101697163   09171 Infectious disease: bacterial    05152 Tuberculosis     101697163   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101697163    05161 Hepatitis B     101697163    05160 Hepatitis C     101697163    05171 Coronavirus disease - COVID-19     101697163    05164 Influenza A     101697163    05162 Measles     101697163    05168 Herpes simplex virus 1 infection     101697163    05163 Human cytomegalovirus infection     101697163    05167 Kaposi sarcoma-associated herpesvirus infection     101697163    05169 Epstein-Barr virus infection     101697163    05165 Human papillomavirus infection     101697163  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101697163 Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101697163 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Interferon Motif Other DBs NCBI-GeneID:  101697163 NCBI-ProteinID:  XP_004875569 LinkDB All DBs Position Un AA seq 187 aa AA seqDB search MAWPLSVLVALVVLTIMSSCSLGCDLPRTHSQGNRRALTLLEQMRRISTFSCLKDREDFG LPHQEFDGKQIQKAQAISVLHEMTSQTFNLFSTQDSSAAWNNGLLDTFCTGLHQQLSDLE ACLTQEVGQEEAPISHEDSRLAVRKYFHRITLYLKEKRYSPCAWEVVRAEIMRSFSSSEK LARKVKD NT seq 564 nt NT seq  +upstreamnt  +downstreamnt atggcctggccactttctgtactggtggccctggtggtgctcaccatcatgtcatcgtgc tctctgggctgtgacctgcctcgaacccacagccaggggaacaggagggccttgacacta ctggaacaaatgaggagaatctccactttctcctgcctgaaggacagagaggactttggc ctcccccaccaggagtttgatggcaaacagatccagaaggctcaggccatctctgtcctc catgagatgaccagccagaccttcaacctcttcagcacacaggattcatctgccgcctgg aacaatggcctgctggacaccttctgcaccggcctccatcagcagctgagtgatctggag gcctgcctgacccaggaggtggggcaggaagaggcgcccatctcgcatgaggactccaga ctggctgtgaggaaatacttccacaggatcactctctacctgaaggagaagcgatacagc ccttgtgcctgggaagttgtcagagcagaaatcatgagatccttctcttcatcggagaaa cttgcaagaaaggtgaaagactaa

Heterocephalus glaber (naked mole rat): 101697684 Help Entry 101697684         CDS       T02812                                  Gene name Ifnl3 Definition (RefSeq) interferon lambda 3   KO K22669   interferon lambda 2/3 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101697684 (Ifnl3)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101697684 (Ifnl3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101697684 (Ifnl3) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101697684 (Ifnl3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL28A Motif Other DBs NCBI-GeneID:  101697684 NCBI-ProteinID:  XP_004859222 LinkDB All DBs Position Un AA seq 171 aa AA seqDB search MKPDPAGGCVLLLLLLLCTVQTRSGEVPVPRPLSVSPDARGCHVAQLQSLSLEERQAFKT AKEALEERRLLKDSTCNSGLFFRAWDLGKLQVWERPMALQAELSLTLKVLASVTDQALWG IVKQPIHTLRHIHAQLRACESPGCLQASVTFNLFRLLTRDLRCVARPDLCA NT seq 516 nt NT seq  +upstreamnt  +downstreamnt atgaagccagaccccgctggaggttgcgtgctgctgctgctgctgctgctgtgcactgta cagaccaggtcaggggaagttcctgtccccagacccctcagtgtctccccggatgcaagg ggctgccacgtggcccagttgcaatctctgtccctagaagagaggcaggccttcaagaca gccaaggaagcattggaagagcggcgcctgctgaaggactccacctgcaactcggggctc ttcttcagggcctgggacctggggaagcttcaagtgtgggagcgccccatggccctgcag gctgagctctccctgacactgaaggtcttggcctcggtgacagaccaggccctgtggggc atcgtgaagcagccgattcacactctgcgtcacatccacgcccagctccgggcctgtgag tcccctggctgcctccaggcctctgtcaccttcaacctcttccgcctgctcacccgggac ctgagatgtgtggccaggccagacctgtgtgcctga

Heterocephalus glaber (naked mole rat): 101698799 Help Entry 101698799         CDS       T02812                                  Definition (RefSeq) interferon lambda-2-like   KO K22669   interferon lambda 2/3 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101698799   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101698799  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101698799 Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101698799 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL28A Motif Other DBs NCBI-GeneID:  101698799 NCBI-ProteinID:  XP_012932835 LinkDB All DBs Position Un AA seq 200 aa AA seqDB search MKPDPAGGCVLLLLLLLCTVQTRSGEVPVPRPLSVSPDARGCHVAQLQSLSLEERQAFKT AKEALEERRLLKDSTCNSGLFFRAWDLGKLQVWERPMALQAELSLTLKVLASVTDQALWG IVKQPIHTLRHIHAQLRACVPAQPKAAHRPCSHRLSRWLQRLNQATKKESPGCLQASVIS NLFFLLTRDLRCLARPDLCA NT seq 603 nt NT seq  +upstreamnt  +downstreamnt atgaagccagaccccgctggaggttgcgtgctgctgctgctgctgctgctgtgcactgta cagaccaggtcaggggaagttcctgtccccagacccctcagtgtctccccggatgcaagg ggctgccacgtggcccagttgcaatctctgtccctagaagagaggcaggccttcaagaca gccaaggaagcattggaagagcggcgcctgctgaaggactccacctgcaactcggggctc ttcttcagggcctgggacctagggaagcttcaagtgtgggagcgccccatggccctgcag gctgagctctccctgacactgaaggtcttggcctcggtgacagaccaggccctgtggggc atcgtgaagcagccgattcacactctgcgtcacatccacgcccagctccgggcctgtgtc ccagctcagcccaaagcagcccacaggccctgcagccaccgcctgtcccgatggctgcag cggctcaaccaggccaccaagaaggagtcccctggctgcctccaggcctctgtcatctcc aacctcttcttcctgctcacccgggacctgagatgtttggccaggccagacctgtgtgcc tga

Heterocephalus glaber (naked mole rat): 101699042 Help Entry 101699042         CDS       T02812                                  Gene name Ifnb1 Definition (RefSeq) interferon beta 1   KO K05415   interferon beta Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04151   PI3K-Akt signaling pathway hgl04217   Necroptosis hgl04380   Osteoclast differentiation hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04622   RIG-I-like receptor signaling pathway hgl04623   Cytosolic DNA-sensing pathway hgl04630   JAK-STAT signaling pathway hgl04650   Natural killer cell mediated cytotoxicity hgl04668   TNF signaling pathway hgl05135   Yersinia infection hgl05142   Chagas disease hgl05152   Tuberculosis hgl05160   Hepatitis C hgl05161   Hepatitis B hgl05162   Measles hgl05163   Human cytomegalovirus infection hgl05164   Influenza A hgl05165   Human papillomavirus infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05168   Herpes simplex virus 1 infection hgl05169   Epstein-Barr virus infection hgl05170   Human immunodeficiency virus 1 infection hgl05171   Coronavirus disease - COVID-19 Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101699042 (Ifnb1)    04668 TNF signaling pathway     101699042 (Ifnb1)    04151 PI3K-Akt signaling pathway     101699042 (Ifnb1)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101699042 (Ifnb1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101699042 (Ifnb1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101699042 (Ifnb1)    04621 NOD-like receptor signaling pathway     101699042 (Ifnb1)    04622 RIG-I-like receptor signaling pathway     101699042 (Ifnb1)    04623 Cytosolic DNA-sensing pathway     101699042 (Ifnb1)    04650 Natural killer cell mediated cytotoxicity     101699042 (Ifnb1)   09158 Development and regeneration    04380 Osteoclast differentiation     101699042 (Ifnb1)  09160 Human Diseases   09171 Infectious disease: bacterial    05135 Yersinia infection     101699042 (Ifnb1)    05152 Tuberculosis     101699042 (Ifnb1)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101699042 (Ifnb1)    05161 Hepatitis B     101699042 (Ifnb1)    05160 Hepatitis C     101699042 (Ifnb1)    05171 Coronavirus disease - COVID-19     101699042 (Ifnb1)    05164 Influenza A     101699042 (Ifnb1)    05162 Measles     101699042 (Ifnb1)    05168 Herpes simplex virus 1 infection     101699042 (Ifnb1)    05163 Human cytomegalovirus infection     101699042 (Ifnb1)    05167 Kaposi sarcoma-associated herpesvirus infection     101699042 (Ifnb1)    05169 Epstein-Barr virus infection     101699042 (Ifnb1)    05165 Human papillomavirus infection     101699042 (Ifnb1)   09174 Infectious disease: parasitic    05142 Chagas disease     101699042 (Ifnb1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101699042 (Ifnb1) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101699042 (Ifnb1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Interferon NYD-SP28 DUF2779 GAT Motif Other DBs NCBI-GeneID:  101699042 NCBI-ProteinID:  XP_004838404 UniProt:  G5CB66 LinkDB All DBs Position Un AA seq 187 aa AA seqDB search MANRCILQIALLLSFSTISLSLSYKLLQAQQRSSSLACGELLKQLKGKPEYCLKDRMDFK FPEEIKQPQHFRKENAALVIQEMLQNILDIVRKNFSNTVWNETIVENLLVELHQQMDSLK TLLQEILEKKDITWEDTMIIPRLKGYYWRIRRHMKAKDNSICAWTVVQVELSRNFSFINR LTDYFQD NT seq 564 nt NT seq  +upstreamnt  +downstreamnt atggccaacaggtgtatcctccaaatcgctctcctgttgtccttctctaccatatctctt tccttaagctacaaattgcttcaagcccaacaacgcagcagcagtttggcctgtggggag cttttgaagcagttgaaaggaaaacctgaatattgcctcaaggacaggatggatttcaaa ttccctgaggagatcaagcaaccacagcacttccggaaggagaatgctgctcttgtcatc caggagatgctccagaatatcttggatattgtcagaaaaaatttctctaacactgtatgg aatgagaccattgttgagaacctccttgttgaactccatcagcagatggacagtctgaag acactcctgcaggaaatactggagaagaaggacattacctgggaggacaccatgatcatt ccacgcctgaaggggtattattggaggatcaggaggcacatgaaggccaaggacaacagc atttgtgcctggacagtagtccaggtagaactctccaggaacttttccttcattaacaga cttacagattatttccaagactga

Heterocephalus glaber (naked mole rat): 101699159 Help Entry 101699159         CDS       T02812                                  Gene name Ifnl2 Definition (RefSeq) interferon lambda-2   KO K22669   interferon lambda 2/3 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101699159 (Ifnl2)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101699159 (Ifnl2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101699159 (Ifnl2) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101699159 (Ifnl2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL28A Motif Other DBs NCBI-GeneID:  101699159 NCBI-ProteinID:  XP_012932836 LinkDB All DBs Position Un AA seq 160 aa AA seqDB search MSPWEIQAFKEARDNLGHASSVGGGKGPPAEGLLVELPLFPGAWGLQKLQVWECPAALQA ELTLTLEVLDNITNLALEDILKQPLHMLRHIRSQLWACVPAHSALSAPRPHSRLLSQWLQ WLKQATKKESPGCLQASVISNLFCLLTWDLRCVARPDQCA NT seq 483 nt NT seq  +upstreamnt  +downstreamnt atgtcaccatgggagatccaggccttcaaggaggcgagggataacttgggccatgcctca tccgtgggaggaggaaaaggacctcccgctgaaggactactggtggagctccccctcttc cccggggcctggggcctgcagaagctgcaggtgtgggagtgccctgcggccctgcaggct gagctcaccctgacactggaggtcctggacaacatcaccaacctggccctggaggacatc ctgaagcagcccctccacatgctgcgtcacatccgctcccagctctgggcctgtgtccca gctcacagtgccctctctgcccccaggccccacagtcgcctcctgtcccagtggctgcag tggctcaagcaggccaccaagaaggagtcccctggctgccttcaggcctctgtcatctcc aacctcttctgcctgctcacctgggacctgagatgtgtggccaggccagaccagtgtgcc taa

Heterocephalus glaber (naked mole rat): 101699626 Help Entry 101699626         CDS       T02812                                  Gene name Ifne Definition (RefSeq) interferon epsilon   KO K05442   interferon epsilon Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04622   RIG-I-like receptor signaling pathway hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101699626 (Ifne)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101699626 (Ifne)  09150 Organismal Systems   09151 Immune system    04622 RIG-I-like receptor signaling pathway     101699626 (Ifne)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101699626 (Ifne) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101699626 (Ifne) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Interferon DUF5357 Avian_gp85 Motif Other DBs NCBI-GeneID:  101699626 NCBI-ProteinID:  XP_012925112 LinkDB All DBs Position Un AA seq 124 aa AA seqDB search MIHKQILEILLVLLASSTIFSLELKLAKEHALVILHEMLQQIFKANISLKGWTDNHIEKF LIEHPQQLEYLETLMGLEASRKNGAXGSENLGLQDTAYFXRMINYLENQGYSRCAQTIVQ VEIN NT seq 375 nt NT seq  +upstreamnt  +downstreamnt atgattcacaagcagatccttgaaattttgttggtgctgctggcctcttccactattttc tccctagaattgaaactggctaaagaacatgcactggttattcttcatgagatgctacag cagatcttcaaggcaaatatttctttgaaaggttggacggataaccacatagagaaattt ctcatcgaacatcctcagcagctagaatacctagaaacactcatggggttggaagctagt aggaaaaatggtgcctgaggtagtgagaacctggggttacaggatacagcatacttctga aggatgataaattacctggaaaaccaaggatacagtagatgtgcccagaccattgtccag gtggaaatcaactga

Heterocephalus glaber (naked mole rat): 101700360 Help Entry 101700360         CDS       T02812                                  Gene name Il22 Definition (RefSeq) interleukin 22   KO K05445   interleukin 22 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway hgl04659   Th17 cell differentiation hgl05321   Inflammatory bowel disease Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101700360 (Il22)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101700360 (Il22)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     101700360 (Il22)  09160 Human Diseases   09163 Immune disease    05321 Inflammatory bowel disease     101700360 (Il22)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101700360 (Il22) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101700360 (Il22) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL22 IL10 Motif Other DBs NCBI-GeneID:  101700360 NCBI-ProteinID:  XP_004861143 UniProt:  G5BGB6 LinkDB All DBs Position Un AA seq 178 aa AA seqDB search MAALQKSVSFSILGTLAASCLLLIALSLQGGAAVPVSSHCVLKKSDFSTYITNLTFMLAE EASFADNNTDVRLIGGKLVRGVNVKERCYLMKQVLNFTLEEVLFPHSDWFQPHMKEVVSF LDGLSNKLSPCHIRGDDQHIQRKVEQLKDTVKKLGESGDIKAISEVNLLLSYLKDYCV NT seq 537 nt NT seq  +upstreamnt  +downstreamnt atggctgctctgcagaaatctgtgagcttttccattttggggactctggctgccagttgc ctccttcttattgccctgtcgcttcagggaggagcagctgtgcctgtcagttcccactgt gtgcttaagaagtctgacttctcgacctatatcaccaacctcaccttcatgctcgctgag gaggccagctttgcagataacaacacagatgtccgtctcattggggggaaactggtccga ggagtcaatgtgaaagagcgctgctatctgatgaagcaggtgctgaactttacccttgaa gaagtgctgtttccccactcagactggttccagccccacatgaaggaggtggtgtccttc ctggatggtctcagcaacaaactcagtccatgtcacatcaggggtgatgaccagcatatc cagaggaaggtggaacagctgaaggacacagtgaaaaagcttggagagagtggagacatc aaagcaattagtgaagtgaatttgctgctttcatacctgaaagattactgtgtctga

Heterocephalus glaber (naked mole rat): 101700722 Help Entry 101700722         CDS       T02812                                  Gene name Ifng Definition (RefSeq) interferon gamma   KO K04687   interferon gamma Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl03050   Proteasome hgl04060   Cytokine-cytokine receptor interaction hgl04066   HIF-1 signaling pathway hgl04217   Necroptosis hgl04350   TGF-beta signaling pathway hgl04380   Osteoclast differentiation hgl04612   Antigen processing and presentation hgl04630   JAK-STAT signaling pathway hgl04650   Natural killer cell mediated cytotoxicity hgl04657   IL-17 signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04659   Th17 cell differentiation hgl04660   T cell receptor signaling pathway hgl04940   Type I diabetes mellitus hgl05140   Leishmaniasis hgl05142   Chagas disease hgl05143   African trypanosomiasis hgl05144   Malaria hgl05145   Toxoplasmosis hgl05146   Amoebiasis hgl05152   Tuberculosis hgl05160   Hepatitis C hgl05164   Influenza A hgl05168   Herpes simplex virus 1 infection hgl05200   Pathways in cancer hgl05235   PD-L1 expression and PD-1 checkpoint pathway in cancer hgl05321   Inflammatory bowel disease hgl05322   Systemic lupus erythematosus hgl05323   Rheumatoid arthritis hgl05330   Allograft rejection hgl05332   Graft-versus-host disease hgl05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:hgl00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    03050 Proteasome     101700722 (Ifng)  09130 Environmental Information Processing   09132 Signal transduction    04350 TGF-beta signaling pathway     101700722 (Ifng)    04630 JAK-STAT signaling pathway     101700722 (Ifng)    04066 HIF-1 signaling pathway     101700722 (Ifng)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101700722 (Ifng)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101700722 (Ifng)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     101700722 (Ifng)    04612 Antigen processing and presentation     101700722 (Ifng)    04660 T cell receptor signaling pathway     101700722 (Ifng)    04658 Th1 and Th2 cell differentiation     101700722 (Ifng)    04659 Th17 cell differentiation     101700722 (Ifng)    04657 IL-17 signaling pathway     101700722 (Ifng)   09158 Development and regeneration    04380 Osteoclast differentiation     101700722 (Ifng)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101700722 (Ifng)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101700722 (Ifng)   09163 Immune disease    05322 Systemic lupus erythematosus     101700722 (Ifng)    05323 Rheumatoid arthritis     101700722 (Ifng)    05321 Inflammatory bowel disease     101700722 (Ifng)    05330 Allograft rejection     101700722 (Ifng)    05332 Graft-versus-host disease     101700722 (Ifng)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     101700722 (Ifng)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     101700722 (Ifng)   09171 Infectious disease: bacterial    05152 Tuberculosis     101700722 (Ifng)   09172 Infectious disease: viral    05160 Hepatitis C     101700722 (Ifng)    05164 Influenza A     101700722 (Ifng)    05168 Herpes simplex virus 1 infection     101700722 (Ifng)   09174 Infectious disease: parasitic    05146 Amoebiasis     101700722 (Ifng)    05144 Malaria     101700722 (Ifng)    05145 Toxoplasmosis     101700722 (Ifng)    05140 Leishmaniasis     101700722 (Ifng)    05142 Chagas disease     101700722 (Ifng)    05143 African trypanosomiasis     101700722 (Ifng)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03051 Proteasome [BR:hgl03051]     101700722 (Ifng)   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101700722 (Ifng)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101700722 (Ifng) Proteasome [BR:hgl03051]  Eukaryotic proteasome   Assembling factors    Other assembling factors     101700722 (Ifng) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101700722 (Ifng) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101700722 (Ifng) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IFN-gamma Motif Other DBs NCBI-GeneID:  101700722 NCBI-ProteinID:  XP_004861144 UniProt:  G5BGB5 LinkDB All DBs Position Un AA seq 164 aa AA seqDB search MKYTSSFLAFQLCIILGFSTYYCESRFTKEINILKDYFNASSSDVGDNGTLFVGILKNCQ EESDKKIFQSQIVSFYFKLFEKSGGNQIVQKSMDTIKEDIIAKFFHSNSSKLDVFQSLTR ISVDNVDFQRRAIIELKKVMDDLSPNQRKRRRSQMLFRGRRASK NT seq 495 nt NT seq  +upstreamnt  +downstreamnt atgaagtatacaagttctttcttggcttttcagctctgcatcattttgggtttctctacc tattattgcgagtcaagatttacaaaagaaataaacattctaaaggactattttaacgca agcagctcagatgtaggagataatggaactcttttcgtaggcattttgaagaattgccaa gaggagagtgacaaaaaaatatttcagagccaaattgtctccttctacttcaaactcttt gaaaaatccggaggcaaccagattgtccaaaagagcatggacaccatcaaggaagacatc atcgctaagttcttccacagcaacagcagcaaactggacgtcttccaaagcctgactcga atttcagtagataatgtggatttccagcgccgagccatcattgaactcaaaaaagtgatg gatgatctgtctccgaaccagcggaaacgaagaaggagtcagatgttgtttcggggccgg agagcatctaaataa

Heterocephalus glaber (naked mole rat): 101701309 Help Entry 101701309         CDS       T02812                                  Gene name Il12b Definition (RefSeq) interleukin 12B   KO K05425   interleukin 12B Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04620   Toll-like receptor signaling pathway hgl04622   RIG-I-like receptor signaling pathway hgl04625   C-type lectin receptor signaling pathway hgl04630   JAK-STAT signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04940   Type I diabetes mellitus hgl05133   Pertussis hgl05134   Legionellosis hgl05140   Leishmaniasis hgl05142   Chagas disease hgl05143   African trypanosomiasis hgl05145   Toxoplasmosis hgl05146   Amoebiasis hgl05152   Tuberculosis hgl05162   Measles hgl05164   Influenza A hgl05168   Herpes simplex virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05205   Proteoglycans in cancer hgl05321   Inflammatory bowel disease hgl05330   Allograft rejection Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101701309 (Il12b)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101701309 (Il12b)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101701309 (Il12b)    04622 RIG-I-like receptor signaling pathway     101701309 (Il12b)    04625 C-type lectin receptor signaling pathway     101701309 (Il12b)    04658 Th1 and Th2 cell differentiation     101701309 (Il12b)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101701309 (Il12b)    05205 Proteoglycans in cancer     101701309 (Il12b)   09163 Immune disease    05321 Inflammatory bowel disease     101701309 (Il12b)    05330 Allograft rejection     101701309 (Il12b)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     101701309 (Il12b)   09171 Infectious disease: bacterial    05133 Pertussis     101701309 (Il12b)    05134 Legionellosis     101701309 (Il12b)    05152 Tuberculosis     101701309 (Il12b)   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     101701309 (Il12b)    05164 Influenza A     101701309 (Il12b)    05162 Measles     101701309 (Il12b)    05168 Herpes simplex virus 1 infection     101701309 (Il12b)   09174 Infectious disease: parasitic    05146 Amoebiasis     101701309 (Il12b)    05145 Toxoplasmosis     101701309 (Il12b)    05140 Leishmaniasis     101701309 (Il12b)    05142 Chagas disease     101701309 (Il12b)    05143 African trypanosomiasis     101701309 (Il12b)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101701309 (Il12b)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101701309 (Il12b) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101701309 (Il12b) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101701309 (Il12b) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL12p40_C fn3 Ig_5 Ig_3 Ig_2 Ig_4 Motif Other DBs NCBI-GeneID:  101701309 NCBI-ProteinID:  XP_004836527 UniProt:  G5BEN1 LinkDB All DBs Position Un AA seq 329 aa AA seqDB search MCHRQLITSWFSLVMLVSPLVAIWELEKDVYVVELDWHPDAPGEMVVLTCDTAEEDGITW TSDQSGDVLGSGKNLTIQVKEFRDAGRYTCHKGVEVLSHLLLLLHKKEDGIWSTDILKDQ KEPKSKTFLKCEATSYSGCFTCWWLTAISTDVTFSVKGSRGSSEPSGVTCGAATLSAERV RVDHREYKKYSVECQEDSTCPAAEERLPIEVVVDAIHKLKYEKYTSSFYIRDIIKPDPPK NLQLKPLMNSHQVEVSWEYPDTWSTPHSYFSLTFAVQVHGKNKKEKKDRLSTDKTSATVS CHKNAKVYVQARDRYYSSSWSEWASVSCS NT seq 990 nt NT seq  +upstreamnt  +downstreamnt atgtgtcatcggcagttgatcacctcctggttttccctggtgatgctagtgtctcctctc gtggccatatgggaactggagaaagatgtttacgtcgtggagttggactggcaccctgat gctcctggagagatggtagttctcacctgtgacactgctgaggaagatggcatcacatgg acctcagaccagagtggtgatgtcttaggctctggtaaaaacctgaccatccaagtgaaa gagttcagagacgccggacggtacacttgtcacaaaggagtcgaggttctgagccatttg ctcctgctacttcacaaaaaggaggatggaatttggtccactgatattttaaaggaccag aaagaacccaaaagcaagacctttctgaaatgtgaggcaacaagttattctggatgtttc acctgctggtggctgacagcaatcagtactgatgtgacattcagtgtcaagggcagcaga ggctcctctgagccttcaggagtgacttgtggagcagcaacactgtccgcagagagggtc agagtggaccacagggagtataagaagtactcagtagagtgccaggaggacagcacctgc cccgccgcagaggagaggctacccattgaggtggtggtggacgctattcacaagctcaag tatgaaaagtataccagcagcttctacatcagagacatcatcaagccagacccaccgaag aacctgcagctgaagccattaatgaattctcatcaggtggaggtcagctgggagtatcct gacacctggagcactccacattcctacttctccctgacgtttgcagttcaggtccacggc aagaataagaaagaaaagaaagatagactctccaccgacaagacctcagccacagtttca tgccacaagaatgcgaaggtgtacgtgcaagcccgggaccgatactatagctcatcttgg agcgaatgggcctctgtgtcctgcagttag

Heterocephalus glaber (naked mole rat): 101701392 Help Entry 101701392         CDS       T02812                                  Gene name Il12a Definition (RefSeq) interleukin 12A   KO K05406   interleukin 12A Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04620   Toll-like receptor signaling pathway hgl04622   RIG-I-like receptor signaling pathway hgl04625   C-type lectin receptor signaling pathway hgl04630   JAK-STAT signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04940   Type I diabetes mellitus hgl05133   Pertussis hgl05134   Legionellosis hgl05140   Leishmaniasis hgl05142   Chagas disease hgl05143   African trypanosomiasis hgl05144   Malaria hgl05145   Toxoplasmosis hgl05146   Amoebiasis hgl05152   Tuberculosis hgl05162   Measles hgl05164   Influenza A hgl05168   Herpes simplex virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05321   Inflammatory bowel disease hgl05330   Allograft rejection Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101701392 (Il12a)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101701392 (Il12a)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101701392 (Il12a)    04622 RIG-I-like receptor signaling pathway     101701392 (Il12a)    04625 C-type lectin receptor signaling pathway     101701392 (Il12a)    04658 Th1 and Th2 cell differentiation     101701392 (Il12a)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101701392 (Il12a)   09163 Immune disease    05321 Inflammatory bowel disease     101701392 (Il12a)    05330 Allograft rejection     101701392 (Il12a)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     101701392 (Il12a)   09171 Infectious disease: bacterial    05133 Pertussis     101701392 (Il12a)    05134 Legionellosis     101701392 (Il12a)    05152 Tuberculosis     101701392 (Il12a)   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     101701392 (Il12a)    05164 Influenza A     101701392 (Il12a)    05162 Measles     101701392 (Il12a)    05168 Herpes simplex virus 1 infection     101701392 (Il12a)   09174 Infectious disease: parasitic    05146 Amoebiasis     101701392 (Il12a)    05144 Malaria     101701392 (Il12a)    05145 Toxoplasmosis     101701392 (Il12a)    05140 Leishmaniasis     101701392 (Il12a)    05142 Chagas disease     101701392 (Il12a)    05143 African trypanosomiasis     101701392 (Il12a)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101701392 (Il12a)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101701392 (Il12a) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101701392 (Il12a) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101701392 (Il12a) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL12 Motif Other DBs NCBI-GeneID:  101701392 NCBI-ProteinID:  XP_004834586 LinkDB All DBs Position Un AA seq 219 aa AA seqDB search MGPSLSFLLLATIVLPVHLSWARSLPRATTVRETFQCLNHSQTLLSAVSSTLQKARQTLE FYSCTPEELDHEDITKDKTSTVKACVPLELVKNESCLASGHTSFITNGSCLTSRKTSFLM TLCLNSIYEDLKLYQLEFKAMNAKLLMDPNRQIFLDQNMLSAIDELMQALNVNSETVPQK PSSEEPDFYKTKIKLCILLHAFRIRAVTIDRMMSYLNSS NT seq 660 nt NT seq  +upstreamnt  +downstreamnt atgggtccttcgctcagcttcctacttttggccaccattgtcctcccagtccatctcagt tgggccaggagcctccctagggccacaacggtcagagaaacgttccagtgccttaaccac tcccaaaccctgctgagcgcagtgagcagcacgcttcaaaaggccagacaaaccctagaa ttttactcctgtactcctgaagagttggatcatgaagatatcacaaaagacaaaaccagc acagtgaaagcctgtgtgccactggaactagtcaagaatgagagctgcctggcttctgga catacttctttcataactaatgggagttgcctgacttccagaaagacctcgtttttgatg accctgtgccttaatagtatctatgaggacttgaaactgtaccagctggagttcaaggcc atgaatgcaaagcttttgatggatcctaacaggcagatctttctagatcaaaacatgctt tcagctattgatgagttgatgcaggccctgaatgtcaacagtgagactgtgccacaaaaa ccttcctctgaagaaccagatttttataaaactaaaatcaagctctgcatacttcttcat gctttcagaattcgtgcagtcactatcgacagaatgatgagttatctgaattcttcctaa

Heterocephalus glaber (naked mole rat): 101702602 Help Entry 101702602         CDS       T02812                                  Gene name Il6 Definition (RefSeq) interleukin 6   KO K05405   interleukin 6 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl01523   Antifolate resistance hgl04060   Cytokine-cytokine receptor interaction hgl04061   Viral protein interaction with cytokine and cytokine receptor hgl04066   HIF-1 signaling pathway hgl04068   FoxO signaling pathway hgl04151   PI3K-Akt signaling pathway hgl04218   Cellular senescence hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04623   Cytosolic DNA-sensing pathway hgl04625   C-type lectin receptor signaling pathway hgl04630   JAK-STAT signaling pathway hgl04640   Hematopoietic cell lineage hgl04657   IL-17 signaling pathway hgl04659   Th17 cell differentiation hgl04668   TNF signaling pathway hgl04672   Intestinal immune network for IgA production hgl04931   Insulin resistance hgl04932   Non-alcoholic fatty liver disease hgl04933   AGE-RAGE signaling pathway in diabetic complications hgl05010   Alzheimer disease hgl05020   Prion disease hgl05022   Pathways of neurodegeneration - multiple diseases hgl05132   Salmonella infection hgl05133   Pertussis hgl05134   Legionellosis hgl05135   Yersinia infection hgl05142   Chagas disease hgl05143   African trypanosomiasis hgl05144   Malaria hgl05146   Amoebiasis hgl05152   Tuberculosis hgl05161   Hepatitis B hgl05162   Measles hgl05163   Human cytomegalovirus infection hgl05164   Influenza A hgl05166   Human T-cell leukemia virus 1 infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05168   Herpes simplex virus 1 infection hgl05169   Epstein-Barr virus infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05202   Transcriptional misregulation in cancer hgl05321   Inflammatory bowel disease hgl05323   Rheumatoid arthritis hgl05332   Graft-versus-host disease hgl05410   Hypertrophic cardiomyopathy Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101702602 (Il6)    04668 TNF signaling pathway     101702602 (Il6)    04066 HIF-1 signaling pathway     101702602 (Il6)    04068 FoxO signaling pathway     101702602 (Il6)    04151 PI3K-Akt signaling pathway     101702602 (Il6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101702602 (Il6)    04061 Viral protein interaction with cytokine and cytokine receptor     101702602 (Il6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     101702602 (Il6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101702602 (Il6)    04620 Toll-like receptor signaling pathway     101702602 (Il6)    04621 NOD-like receptor signaling pathway     101702602 (Il6)    04623 Cytosolic DNA-sensing pathway     101702602 (Il6)    04625 C-type lectin receptor signaling pathway     101702602 (Il6)    04659 Th17 cell differentiation     101702602 (Il6)    04657 IL-17 signaling pathway     101702602 (Il6)    04672 Intestinal immune network for IgA production     101702602 (Il6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101702602 (Il6)    05202 Transcriptional misregulation in cancer     101702602 (Il6)   09163 Immune disease    05323 Rheumatoid arthritis     101702602 (Il6)    05321 Inflammatory bowel disease     101702602 (Il6)    05332 Graft-versus-host disease     101702602 (Il6)   09164 Neurodegenerative disease    05010 Alzheimer disease     101702602 (Il6)    05020 Prion disease     101702602 (Il6)    05022 Pathways of neurodegeneration - multiple diseases     101702602 (Il6)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     101702602 (Il6)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     101702602 (Il6)    04931 Insulin resistance     101702602 (Il6)    04933 AGE-RAGE signaling pathway in diabetic complications     101702602 (Il6)   09171 Infectious disease: bacterial    05132 Salmonella infection     101702602 (Il6)    05135 Yersinia infection     101702602 (Il6)    05133 Pertussis     101702602 (Il6)    05134 Legionellosis     101702602 (Il6)    05152 Tuberculosis     101702602 (Il6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101702602 (Il6)    05161 Hepatitis B     101702602 (Il6)    05171 Coronavirus disease - COVID-19     101702602 (Il6)    05164 Influenza A     101702602 (Il6)    05162 Measles     101702602 (Il6)    05168 Herpes simplex virus 1 infection     101702602 (Il6)    05163 Human cytomegalovirus infection     101702602 (Il6)    05167 Kaposi sarcoma-associated herpesvirus infection     101702602 (Il6)    05169 Epstein-Barr virus infection     101702602 (Il6)   09174 Infectious disease: parasitic    05146 Amoebiasis     101702602 (Il6)    05144 Malaria     101702602 (Il6)    05142 Chagas disease     101702602 (Il6)    05143 African trypanosomiasis     101702602 (Il6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101702602 (Il6)    01523 Antifolate resistance     101702602 (Il6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101702602 (Il6) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101702602 (Il6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL6 IL23 CENP_C_N Motif Other DBs NCBI-GeneID:  101702602 NCBI-ProteinID:  XP_004839876 LinkDB All DBs Position Un AA seq 253 aa AA seqDB search MVLLPCEGGVWLSEGWRLASSNSRLTAVLSAHWLLSLPFGTGTFRPLALWGLLLVTVTAA PTSQVLKDFRADTTSSKPTTSNSQAFRLFTLVLHDVQELKSETCKHNVNCLEEEKAMLNN LNLPKIKIEDGCFYGGYNWETCHLKIITGLLKFQIYLQYMQNKLQSDSENEKAEKIYTSV KSLSLFMKAKVSNTEQTVFPSPTANATLLEELESQNETQKLLIVQIVLCSLEEFLQNSLR PIRKAGSDLDLDI NT seq 762 nt NT seq  +upstreamnt  +downstreamnt atggtgctcctcccttgtgagggaggtgtgtggctgagtgagggctggcgtctggccagc tccaacagcaggctcacagctgtgctgtcagctcactggctgctctcccttcccttcggc acaggcaccttccgtccacttgccttgtgggggctgctcctggtaacagttactgctgct cccacctcacaagttctgaaagatttcagggctgatacgacgtcaagtaagccaacaacc tctaattcacaagcgtttcgactgtttacgctagtcctccacgatgtccaggaactgaaa agtgagacgtgcaaacataatgtcaattgcctagaggaggaaaaggcaatgttaaacaac ctgaacctcccaaagataaaaatagaagatggatgcttctacggtggatacaactgggaa acatgccacttgaaaatcatcactggtcttctgaagttccagatctacctgcagtacatg cagaacaagcttcagagtgactctgaaaatgaaaaagctgaaaaaatatacactagtgtc aaaagcttgagtctgttcatgaaagctaaggtaagcaatacagaacagacagtcttccct agcccaactgcgaatgccaccctgctggaggagctggagtcacagaatgagactcagaag cttttgatagttcaaatcgttctgtgcagccttgaagaattcctgcagaatagtctgagg cctattcggaaagcaggttcagacttggacttagatatctaa

Heterocephalus glaber (naked mole rat): 101703771 Help Entry 101703771         CDS       T02812                                  Gene name Ctf1 Definition (RefSeq) cardiotrophin 1   KO K05422   cardiotrophin 1 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101703771 (Ctf1)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101703771 (Ctf1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101703771 (Ctf1) Cytokines and growth factors [BR:hgl04052]  Cytokines   CSF and other factors    101703771 (Ctf1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  CNTF PRF Nup54 NolB Motif Other DBs NCBI-GeneID:  101703771 NCBI-ProteinID:  XP_004856250 LinkDB All DBs Position Un AA seq 197 aa AA seqDB search MSLREGSLEDPQADSSVSFLPHLEAKIRQTHSLARLLTKYAEQLLQEYVQHQGAPFGSPG FSPPRLPVAGLSAPAPGHAGLPLAERLRLDAEALAELPPLLDAVRHRQAELSPRALRLLR RLEDATRQTRALGAALEAVLAALGAAAPGPRREPPAAPGPAGVFPAKLLGLRVCGLYREW TRRTEGDLGQLLPGGPA NT seq 594 nt NT seq  +upstreamnt  +downstreamnt atgagcctgagggagggaagtctggaagacccccaggctgactcctcagtctcattcctt ccccacttggaggccaagatccgccagacacacagccttgcccgcctcctcaccaaatat gctgagcagctgctccaggaatatgtgcagcaccagggagcccccttcggctcgcccggc ttctcgccgccgcggctgccggtggccggcctgagcgcgccggcgccgggccacgcgggg ctgccgctggccgagcggctgcgcttggacgccgaggcgctggccgagctgcccccgctg ttggatgccgtgcgccaccgccaggccgagctgagcccgcgcgcgctgcgcctgctgcgg cgcctggaggacgcgacgcgccagacccgcgcgctgggtgccgccctggaggccgtgctg gccgcgctgggcgccgccgccccggggccccgccgcgagcccccggccgcccccggcccc gcgggcgtcttcccagccaagctgctggggctgcgcgtgtgcggcctctaccgcgagtgg acgcgccgcaccgagggagacctgggccagctgctgcccgggggccccgcctga

Heterocephalus glaber (naked mole rat): 101704388 Help Entry 101704388         CDS       T02812                                  Definition (RefSeq) cardiotrophin-2   KO K24382   cardiotrophin 2 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101704388   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101704388  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101704388 Cytokines and growth factors [BR:hgl04052]  Cytokines   CSF and other factors    101704388 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PRF CNTF LIF_OSM IL11 Motif Other DBs NCBI-GeneID:  101704388 NCBI-ProteinID:  XP_004856252 UniProt:  G5BYK0 LinkDB All DBs Position Un AA seq 220 aa AA seqDB search MNELAARAQPQGPGAELGFPLPAPLCLLSLLLPSPSLAAPISPAEPISQAYSLALYMQKN TSTLLQTYLQYQGSPFSDPGFSAPELQLSSLPSAAVSFKTWHALEDRERLSRAQRAFLAL TQHLQLVGDDQIDLNPGSPVLLAQLGVARLRAQGLLGNVAAIMNALGLPIPPEEDTLGLV PFGASTFERKCRGYVVTREYGHWTDRAVRDLALLKAKYPV NT seq 663 nt NT seq  +upstreamnt  +downstreamnt atgaatgaactggcagccagggctcagcctcaaggacccggtgctgagcttggatttcct ctgccagcccccctctgcctgctgagcctgctgttgccatccccgagtctggcagccccc atctcccccgctgagcccatcagtcaagcctatagcctggccctctacatgcagaagaac acgtccacgctgctgcagacttacctccagtaccagggcagcccttttagtgaccctggc ttctcagcccctgagctccagctcagcagcctgccttctgccgcagtctccttcaagacc tggcatgccctggaagaccgggagcggctaagccgtgcccagagagccttcctggccttg acccagcacctccagctcgtgggggatgaccagatcgacctgaatcctggtagtcctgtc ctgctggcccagctcggagtggcgagactaagggcccaaggtctgcttggcaatgtggct gccatcatgaacgccctggggctgcctattcccccagaagaggacactctaggtcttgtc ccctttggggcctccacgttcgagagaaaatgtcgagggtatgtagtgacccgggaatat gggcactggacagacagagctgtgagggatttggctctgctcaaggccaagtatccagtg tga

Heterocephalus glaber (naked mole rat): 101705496 Help Entry 101705496         CDS       T02812                                  Gene name Osm Definition (RefSeq) oncostatin M   KO K05418   oncostatin M Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04151   PI3K-Akt signaling pathway hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101705496 (Osm)    04151 PI3K-Akt signaling pathway     101705496 (Osm)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101705496 (Osm)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101705496 (Osm) Cytokines and growth factors [BR:hgl04052]  Cytokines   CSF and other factors    101705496 (Osm) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LIF_OSM Motif Other DBs NCBI-GeneID:  101705496 NCBI-ProteinID:  XP_004844122 LinkDB All DBs Position Un AA seq 279 aa AA seqDB search MRAQLTWRTLLNPDRVTWGSSKGALRSARLGALPLGSSQQLVLPKGLRGLVLGLLLLSPA VEAAVAMCRCSNSYTQLLGQLRSQANLMKDTSCLLEPFIRLQGLDTPVLRESCMKCSRAF PSEDTLRGLSRHGFLQTVSATLNGILHRLAALQQHLLKGKNMPEMQVATRNIQGVRNNIY CMSELLTNCSETPEPLLPGPRATLMPSTLNFFKSKLEGCQFLCGYHRFMGSVGQVFGEWG NSLSRNRRHSPRQALHKGARRARPSRRVKRPVPRGQLFR NT seq 840 nt NT seq  +upstreamnt  +downstreamnt atgcgggcacaactcacatggaggacgctgctcaatcccgaccgagtcacctggggaagt agcaagggtgccttgcggtcggcacgcctgggcgccctgcccctcggctcttcccagcag ctggtcctccccaaggggctgcgcggtctggtcctcggactcctgctcctgagcccagca gtggaggcggcagtggccatgtgcagatgctccaactcttacacacagctcctcggccag ctccggagccaggcgaacctcatgaaggacaccagctgcctcctggagccctttatccgc ctccaaggcctggacacacctgtcctgagagagtcctgcatgaaatgttccagggccttc cccagtgaggacaccctgcgggggctgagcaggcatggctttctgcagactgtcagtgcc accctgaacggcatcctgcacagactggctgctttacagcagcatctcttgaagggcaag aacatgccagagatgcaggtggccacgaggaacatccagggcgtcaggaacaacatctac tgcatgtcagagctgctcaccaactgctcagagacgccagagcccctgctgcctggccca cgggccacactgatgccctctaccctgaacttcttcaaatccaagctggagggctgccag ttcctgtgtggctaccaccgcttcatgggctctgtggggcaggtctttggggagtggggg aacagcctgagtcgtaaccggagacacagcccccgccaggccctgcataagggggcccgc agggccaggccctccagaagggtcaagaggcctgtgcccagggggcagctgttccggtag

Heterocephalus glaber (naked mole rat): 101706414 Help Entry 101706414         CDS       T02812                                  Gene name Il4 Definition (RefSeq) interleukin 4   KO K05430   interleukin 4 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04151   PI3K-Akt signaling pathway hgl04630   JAK-STAT signaling pathway hgl04640   Hematopoietic cell lineage hgl04657   IL-17 signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04659   Th17 cell differentiation hgl04660   T cell receptor signaling pathway hgl04664   Fc epsilon RI signaling pathway hgl04672   Intestinal immune network for IgA production hgl05140   Leishmaniasis hgl05200   Pathways in cancer hgl05310   Asthma hgl05320   Autoimmune thyroid disease hgl05321   Inflammatory bowel disease hgl05330   Allograft rejection Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101706414 (Il4)    04151 PI3K-Akt signaling pathway     101706414 (Il4)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101706414 (Il4)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101706414 (Il4)    04660 T cell receptor signaling pathway     101706414 (Il4)    04658 Th1 and Th2 cell differentiation     101706414 (Il4)    04659 Th17 cell differentiation     101706414 (Il4)    04657 IL-17 signaling pathway     101706414 (Il4)    04664 Fc epsilon RI signaling pathway     101706414 (Il4)    04672 Intestinal immune network for IgA production     101706414 (Il4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101706414 (Il4)   09163 Immune disease    05310 Asthma     101706414 (Il4)    05320 Autoimmune thyroid disease     101706414 (Il4)    05321 Inflammatory bowel disease     101706414 (Il4)    05330 Allograft rejection     101706414 (Il4)   09174 Infectious disease: parasitic    05140 Leishmaniasis     101706414 (Il4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101706414 (Il4)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101706414 (Il4) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101706414 (Il4) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101706414 (Il4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL4 Motif Other DBs NCBI-GeneID:  101706414 NCBI-ProteinID:  XP_012932792 UniProt:  G5ASQ0 LinkDB All DBs Position Un AA seq 140 aa AA seqDB search MGLVPQLTVTLFCLLACTGTFVRGCNDALQEIINDLNVLSSQKTPCAELAAADVFAAPKD TAEKLCQAVTVLHRTSYLGVGLSCLNRHRESVFLVLLKKVYRNLRSMVQPNCSVSELKQT TLKDFLENLKTILKKKYSEC NT seq 423 nt NT seq  +upstreamnt  +downstreamnt atgggtcttgtcccccagctgacagtcaccctgttctgcctcctagcatgtaccggcacc ttcgtccgtggctgcaacgatgccttacaagaaatcatcaatgatctgaatgtgctctca agccaaaagactccatgtgctgagctggctgctgcagacgtcttcgctgcccccaaggac acagccgagaagctgtgccaggctgtgacagtgctgcatcgcacatcctacctcggggtg gggctttcgtgcctgaacagacacagagaatcagtctttctggttctcctgaagaaggtc tacaggaacctcaggagcatggttcagccgaactgttctgtgagtgaactcaagcagacg acgttgaaagacttcttggaaaacctaaaaacgatcctgaaaaagaaatactcagagtgt tga

Heterocephalus glaber (naked mole rat): 101706424 Help Entry 101706424         CDS       T02812                                  Gene name Ifnk Definition (RefSeq) interferon kappa   KO K05441   interferon kappa Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04622   RIG-I-like receptor signaling pathway hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101706424 (Ifnk)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101706424 (Ifnk)  09150 Organismal Systems   09151 Immune system    04622 RIG-I-like receptor signaling pathway     101706424 (Ifnk)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101706424 (Ifnk) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101706424 (Ifnk) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Interferon Motif Other DBs NCBI-GeneID:  101706424 NCBI-ProteinID:  XP_004838527 LinkDB All DBs Position Un AA seq 171 aa AA seqDB search MIPKYLRLVYFVGLFIRHIQSQDCTLQNVRLSTVTKENVRLLSSVSNPLPLRCLREIKAF GLPQNILSYSQHVERDIKEVFYDIIIQAFNIFSRHTSDSTWKEEYLTQIKRVQVVQQSKL ALRGYFQRIENYLKDKKYSYCAWKIVQVEIKRCFFYFLKFIKLPRGNKVYF NT seq 516 nt NT seq  +upstreamnt  +downstreamnt atgattccaaaatacttaaggcttgtgtactttgtgggtctgttcattagacacatccaa tctcaggactgtaccttacagaatgttcgcttgagtacagtcaccaaggagaatgtgaga cttctgagcagtgtgagcaatccacttcctctgagatgtctaagagagatcaaagctttt ggattgccccaaaatatcctctcatactctcagcatgtggaaagggacatcaaggaagtc ttctatgatattatcatacaggccttcaacatcttcagccgacacacctccgactccact tggaaagaggaatacctgacacaaatcaaaagagttcaggtcgtccagcagagcaaacta gcattgagaggatatttccaaagaatagaaaattacctaaaggataagaaatacagttac tgtgcctggaagattgtgcaagtggaaatcaaaagatgtttcttctactttctgaaattc ataaagctacccagaggaaataaggtatacttttag

Heterocephalus glaber (naked mole rat): 101706608 Help Entry 101706608         CDS       T02812                                  Gene name Il11 Definition (RefSeq) interleukin 11   KO K05417   interleukin 11 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway hgl04640   Hematopoietic cell lineage hgl05323   Rheumatoid arthritis Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101706608 (Il11)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101706608 (Il11)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101706608 (Il11)  09160 Human Diseases   09163 Immune disease    05323 Rheumatoid arthritis     101706608 (Il11)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101706608 (Il11) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101706608 (Il11) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL11 Motif Other DBs NCBI-GeneID:  101706608 NCBI-ProteinID:  XP_012921617 LinkDB All DBs Position Un AA seq 120 aa AA seqDB search MSASALGALQLPSVLTRLRTDLLSYLRHVQWLRRVGGPSLRTLEPELGTLQARLDRLLRR LQLLMSVLALPQVPPEPPTPPLAPPASAWGGIRAAHAVLGGLHLTLDWAVRGLLLLKTRL NT seq 363 nt NT seq  +upstreamnt  +downstreamnt atgagtgcgagtgcactgggagccctgcagctgcccagcgtgctcacgaggttgcggact gacctgctgtcctacctgcgacacgtgcagtggctgcgccgggtgggtggcccttcgctg aggaccctggagcctgagctgggcaccctgcaggcccggctggaccggctcctgcgcagg ctgcagctcctgatgtccgtcctggccctgccccaggtgcccccagaaccgcccacacca cccctggcacctcctgcctcagcctggggaggcatccgggcggcccacgccgtcctgggt gggctgcacctcaccctggactgggccgtgcgggggctgctgctgctgaagacccggctg tga

Heterocephalus glaber (naked mole rat): 101707178 Help Entry 101707178         CDS       T02812                                  Gene name Il24 Definition (RefSeq) interleukin 24   KO K22668   interleukin 24 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04061   Viral protein interaction with cytokine and cytokine receptor hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101707178 (Il24)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101707178 (Il24)    04061 Viral protein interaction with cytokine and cytokine receptor     101707178 (Il24)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101707178 (Il24) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101707178 (Il24) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL10 IL22 Motif Other DBs NCBI-GeneID:  101707178 NCBI-ProteinID:  XP_004862336 LinkDB All DBs Position Un AA seq 329 aa AA seqDB search MLPTFNCDKFVTLLVHREFTVGALIHLAAKCPYTVCADSTAEYTPSFSSFLARGAERSCA FFTAIRAEPPPPGSSAVPTAATVIAGRQVPEPRRRRHRGALRGAEGSDLSGPASLGHAAG ERGSGAELRPRLKDQLPADSRTAGPEMGPWLQTAAFPLLGLILLLWSQVPGLQGHEFRFG PCRVEGVALPSLWEAFRSLKDTVQAQDNITSIRLLRREVLQNVSDTESCHLIHDLLKFYL NTVFKNYHHKIAESNMLPSFSTLANNFVFIVSKLQPSQKNEMLSVSDRARRRFLMFKRAF KQLEIEAALTKAFGEVDILLTWMGRFYQF NT seq 990 nt NT seq  +upstreamnt  +downstreamnt atgctgcccacattcaactgtgacaagtttgtgacacttcttgtgcaccgagagtttaca gttggtgcacttatacatctggcggccaagtgcccctacacggtctgtgcagacagtaca gcagagtacactccgagtttctccagtttcttggcccgcggtgcggagcgcagctgcgcc ttcttcacggcgatccgggccgagccgccgcctcccgggtcctcggcagtgcccaccgcc gccactgtgatcgctggacggcaggtgcccgagccccggcggcggcggcacaggggggcc ctgcggggagcggagggcagcgacctgagcggccccgccagcctcggacatgcggccggg gagcgaggctcgggcgccgagttgaggccccgcctgaaggaccagctccctgcagacagc cggacagccggacctgagatgggcccttggctccagacggctgccttccctcttctcggt ctgatcctgcttctctggagccaggtgcccgggctccagggccacgagttccggtttggg ccatgccgagtggagggagtggctctccccagcctgtgggaggccttccggagcctgaag gacactgtgcaagctcaggacaacatcacgagcatccggctgctgcggcgagaggtcctg cagaacgtctcggacactgagagctgccacctcatccacgacctgctgaagttctacctg aacactgtgtttaaaaactaccaccacaaaatcgctgagtccaacatgctgccctccttc tctaccctggccaacaactttgttttcattgtgtcaaaacttcaacccagtcagaagaat gagatgctctctgtcagtgacagagcgcgtaggcggttcctgatgttcaagagagcgttc aaacagttggagattgaagcagctctgaccaaagcctttggggaagtggacattctccta acctggatgggcagattctaccagttctga

Heterocephalus glaber (naked mole rat): 101707249 Help Entry 101707249         CDS       T02812                                  Gene name Il17d Definition (RefSeq) interleukin 17D   KO K05492   interleukin 17D Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04625   C-type lectin receptor signaling pathway hgl04630   JAK-STAT signaling pathway hgl04657   IL-17 signaling pathway hgl04659   Th17 cell differentiation Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101707249 (Il17d)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101707249 (Il17d)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     101707249 (Il17d)    04659 Th17 cell differentiation     101707249 (Il17d)    04657 IL-17 signaling pathway     101707249 (Il17d)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101707249 (Il17d) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101707249 (Il17d) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL17 Motif Other DBs NCBI-GeneID:  101707249 NCBI-ProteinID:  XP_004854928 LinkDB All DBs Position Un AA seq 216 aa AA seqDB search MLGGLRSAARPVPQVWMLVAGLLLALTPGRAAVRAGRRPARQRGCADRPEELLEQLYGRL AAGVLSAFHHTLQLGPREQARNASCPAGGRPADRRFRPPANLRSVSPWAYRISYDPARFP RYLPEAYCLCRGCLTGPFGDEDFRFRSTPVYMPAVVLRRTSACAGGRSVYTEAYITVPVG CTCVPQLEKDTASINSSIDKQGAKLLLGPSDEPGSP NT seq 651 nt NT seq  +upstreamnt  +downstreamnt atgctcgggggcttacgttctgcggcgcggcctgtcccgcaggtctggatgctcgtggca ggccttctgctggcgctaacgccgggccgcgccgcggttagggcgggcaggcgcccggcg cggcagcggggctgcgcggaccgacccgaggagctcctggagcagctgtacgggaggctg gcggccggcgtgctcagcgccttccaccacaccttgcagctgggcccccgcgagcaggcg cgcaatgcgagctgcccggcagggggcaggcccgccgaccgccgcttccggccgcccgcc aacctgcgcagcgtctcgccctgggcctacaggatttcgtatgacccagcgaggttccca cggtaccttcccgaagcctactgcctgtgccggggctgcctgaccgggccctttggcgat gaggacttccgcttccgcagtacccccgtgtacatgcccgctgtggtcctgcgccgcacc tcggcctgcgccggcggccgttctgtctacactgaggcctacatcacggtgcccgtcggc tgcacttgcgttcctcagctggagaaggacacggccagcatcaactccagcatcgacaag cagggtgccaaactgctgcttggccccagtgatgagccaggcagcccctga

Heterocephalus glaber (naked mole rat): 101707902 Help Entry 101707902         CDS       T02812                                  Gene name Il23a Definition (RefSeq) interleukin 23 subunit alpha   KO K05426   interleukin 23 subunit alpha Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04625   C-type lectin receptor signaling pathway hgl04630   JAK-STAT signaling pathway hgl04659   Th17 cell differentiation hgl05133   Pertussis hgl05152   Tuberculosis hgl05200   Pathways in cancer hgl05321   Inflammatory bowel disease hgl05323   Rheumatoid arthritis Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101707902 (Il23a)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101707902 (Il23a)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     101707902 (Il23a)    04659 Th17 cell differentiation     101707902 (Il23a)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101707902 (Il23a)   09163 Immune disease    05323 Rheumatoid arthritis     101707902 (Il23a)    05321 Inflammatory bowel disease     101707902 (Il23a)   09171 Infectious disease: bacterial    05133 Pertussis     101707902 (Il23a)    05152 Tuberculosis     101707902 (Il23a)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101707902 (Il23a) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101707902 (Il23a) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL23 IL6 Motif Other DBs NCBI-GeneID:  101707902 NCBI-ProteinID:  XP_004861356 UniProt:  G5BB75 LinkDB All DBs Position Un AA seq 189 aa AA seqDB search MLGSTAVMLLLLLPWIAQGRAVAGSNNAAWAQCQQLSQKLCTLAWSAHPLVGHVDPPREE GDEETADDVPHIQCGDGCDPQGLKDNSQFCLQRIYQGLIFYQKLLGSDIFTGEPSLLPDG PVGQLHASLLGLSQLLQPEDHQQETQTPSLSPSQPWQRLLLRIKILRSLQAFVAVAARVF AHGATTLSP NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgctgggaagcacagctgtgatgctgctactgctgctcccctggattgctcagggccgg gctgtggctgggagcaacaacgctgcctgggcccagtgccagcagctgtcacagaagctc tgcacgctggcttggagtgcacatccattagtgggacatgtggacccaccaagagaagag ggagatgaagagactgcagacgatgtcccccatatccagtgtggggatggctgtgatcca caaggactcaaagacaacagtcagttctgtttgcagaggatctaccagggtctaattttt taccagaaactgctgggctcagacattttcacaggggagccttcactactccctgatggc cccgtaggccagcttcatgcctccctgctgggcctcagccaactcctgcagcctgaggat caccaacaggagactcagactccgagcctcagccccagccagccatggcagcgcctcctt cttcgtatcaagatcctacgcagcctccaggcctttgtggctgtagctgcccgagtcttt gcccatggagccacaactctgagcccctaa

Heterocephalus glaber (naked mole rat): 101707909 Help Entry 101707909         CDS       T02812                                  Gene name Il20 Definition (RefSeq) interleukin 20   KO K22667   interleukin 20 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04061   Viral protein interaction with cytokine and cytokine receptor hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101707909 (Il20)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101707909 (Il20)    04061 Viral protein interaction with cytokine and cytokine receptor     101707909 (Il20)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101707909 (Il20) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101707909 (Il20) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL10 DUF4874 DUF5807 Motif Other DBs NCBI-GeneID:  101707909 NCBI-ProteinID:  XP_004862338 UniProt:  A0A0P6IWS2 LinkDB All DBs Position Un AA seq 176 aa AA seqDB search MKTSGLAFGLLSATFYLLWTPSSGLKILHLGSCVIVTNLQEIQSEFSEIRDSVQASDKNI DFRILRNTGSLQDTEPSDRCCLLRHLLRLYLDRVFKNYQTSDYHTLRKLSSLANSFLTMK KDLQLCHAYMTCHCGEEATEKYRQILSHFEQLEPQAAAVKVLGELDILLRWMDEAE NT seq 531 nt NT seq  +upstreamnt  +downstreamnt atgaaaacctctggtcttgccttcggccttctctctgccacattttatctcctctggact ccttcatctgggctcaagattctccatttgggaagctgtgtgattgtcacaaacctccag gaaatacaaagtgaattttctgagatccgggacagtgtgcaagccagtgacaaaaacatt gacttcagaatcttaaggaacaccggatctttgcaagacacagagccttcagaccggtgt tgcctcctccgccacttactgagactctacctggacagagtattcaaaaactaccagacc tctgattaccacacactccggaagctcagcagtctggcgaattcctttcttactatgaaa aaggacctccagctctgtcatgcctacatgacgtgccattgcggggaggaagcaacggag aaatacaggcagattctgagtcactttgaacagctggagcctcaggcagcagcagtgaag gttttgggggaactagacattcttctgcgatggatggatgaggcagaatag

Heterocephalus glaber (naked mole rat): 101708273 Help Entry 101708273         CDS       T02812                                  Gene name Il10 Definition (RefSeq) interleukin 10   KO K05443   interleukin 10 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04061   Viral protein interaction with cytokine and cytokine receptor hgl04068   FoxO signaling pathway hgl04625   C-type lectin receptor signaling pathway hgl04630   JAK-STAT signaling pathway hgl04660   T cell receptor signaling pathway hgl04672   Intestinal immune network for IgA production hgl05133   Pertussis hgl05135   Yersinia infection hgl05140   Leishmaniasis hgl05142   Chagas disease hgl05143   African trypanosomiasis hgl05144   Malaria hgl05145   Toxoplasmosis hgl05146   Amoebiasis hgl05150   Staphylococcus aureus infection hgl05152   Tuberculosis hgl05310   Asthma hgl05320   Autoimmune thyroid disease hgl05321   Inflammatory bowel disease hgl05322   Systemic lupus erythematosus hgl05330   Allograft rejection Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101708273 (Il10)    04068 FoxO signaling pathway     101708273 (Il10)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101708273 (Il10)    04061 Viral protein interaction with cytokine and cytokine receptor     101708273 (Il10)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     101708273 (Il10)    04660 T cell receptor signaling pathway     101708273 (Il10)    04672 Intestinal immune network for IgA production     101708273 (Il10)  09160 Human Diseases   09163 Immune disease    05310 Asthma     101708273 (Il10)    05322 Systemic lupus erythematosus     101708273 (Il10)    05320 Autoimmune thyroid disease     101708273 (Il10)    05321 Inflammatory bowel disease     101708273 (Il10)    05330 Allograft rejection     101708273 (Il10)   09171 Infectious disease: bacterial    05135 Yersinia infection     101708273 (Il10)    05133 Pertussis     101708273 (Il10)    05150 Staphylococcus aureus infection     101708273 (Il10)    05152 Tuberculosis     101708273 (Il10)   09174 Infectious disease: parasitic    05146 Amoebiasis     101708273 (Il10)    05144 Malaria     101708273 (Il10)    05145 Toxoplasmosis     101708273 (Il10)    05140 Leishmaniasis     101708273 (Il10)    05142 Chagas disease     101708273 (Il10)    05143 African trypanosomiasis     101708273 (Il10)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101708273 (Il10)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101708273 (Il10) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101708273 (Il10) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101708273 (Il10) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL10 IL22 Motif Other DBs NCBI-GeneID:  101708273 NCBI-ProteinID:  XP_004862339 UniProt:  G5BP21 LinkDB All DBs Position Un AA seq 178 aa AA seqDB search MPSSALLCCLVLLAGVRASQGMDTQSKDSCTRFPAGLPHMLQELRAAFGRVKTFFQTKDP LDNTLLSQSLLEDFKGYLGCQALSEMIQFYLVEVMPKAENHDPDIKQHVNSLGEKLKTLR LQLRRCHRFLPCENKSRAVEQVKDAFSKLQEKGVYKAMSEFDIFINYIEAYMTEKAAD NT seq 537 nt NT seq  +upstreamnt  +downstreamnt atgcccagctcagcactgctgtgttgcctggtcttactggctggggtcagggccagccaa ggcatggacacccagtctaaggactcctgcacccgcttcccagccggcctgccccacatg ctccaagagctccgagctgcctttggcagagtgaagactttctttcaaacaaaggatcca ctggacaacacgctgctgagccagtctttgctggaggactttaagggttacctgggctgc caagccttgtcggagatgatccagttctacctggtggaggtgatgcccaaggcggagaat cacgacccagacatcaagcagcacgtgaactccctgggggaaaagctcaagactctcagg ctgcagctgcggcgctgtcaccggttccttccctgtgaaaataaaagcagagcggtggag caggtgaaggacgccttcagcaagctccaggagaaaggtgtctacaaagccatgagtgag tttgacatcttcatcaactacatcgaagcctacatgacagagaaggcagcagactaa

Heterocephalus glaber (naked mole rat): 101713016 Help Entry 101713016         CDS       T02812                                  Gene name Il9 Definition (RefSeq) interleukin 9   KO K05432   interleukin 9 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway hgl05310   Asthma Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101713016 (Il9)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101713016 (Il9)  09160 Human Diseases   09163 Immune disease    05310 Asthma     101713016 (Il9)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101713016 (Il9) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101713016 (Il9) BRITE hierarchy SSDB OrthologParalogGFIT Other DBs NCBI-GeneID:  101713016 NCBI-ProteinID:  XP_004836821 LinkDB All DBs Position Un AA seq 144 aa AA seqDB search MPLVTVLTSALIFCSVAGQRCSTSSGIRYINYLISNLQKDPLSTCSCSANVTSCLCLPIP SDNCTMPCFQEGLSQMTNITQKTKFSLTFNQVKRTVEVLKNNKCPSFSCEQPCNQTTAGN TVTFLRNLLELFQRETMKGMRARA NT seq 435 nt NT seq  +upstreamnt  +downstreamnt atgcctctggtcacagtcctcacctctgccttgatcttctgctccgttgcaggccagagg tgctccacttcctcaggaatcaggtacatcaactacctcatcagcaatctgcagaaagat ccgctgtccacatgcagctgcagtgccaacgtgaccagttgcttgtgcttgcctatccct tctgacaactgcactatgccatgtttccaggaggggctgtcacagatgaccaacatcaca cagaaaacaaaattctcgttgactttcaatcaggtgaaaagaacagttgaagtcctaaag aacaacaagtgtccatctttttcttgtgaacagccttgcaaccaaaccacagcaggcaac acggtgacatttctgaggaatctcctggaacttttccagagagaaacgatgaaagggatg agagctcgagcatga

Heterocephalus glaber (naked mole rat): 101713065 Help Entry 101713065         CDS       T02812                                  Gene name Lif Definition (RefSeq) leukemia inhibitory factor   KO K05419   leukemia inhibitory factor Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04550   Signaling pathways regulating pluripotency of stem cells hgl04630   JAK-STAT signaling pathway hgl04668   TNF signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101713065 (Lif)    04668 TNF signaling pathway     101713065 (Lif)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101713065 (Lif)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     101713065 (Lif)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101713065 (Lif) Cytokines and growth factors [BR:hgl04052]  Cytokines   CSF and other factors    101713065 (Lif) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LIF_OSM Motif Other DBs NCBI-GeneID:  101713065 NCBI-ProteinID:  XP_004843487 UniProt:  G5APV6 LinkDB All DBs Position Un AA seq 200 aa AA seqDB search MKVLAAGVMPLLLVLHWKYGAGSPLPSVNATCATRHQCHSSVMSQIRNQLAQLNSSANAL FILYYTAQGDPFPSNLDKLCAPNVTDFPAFHANGTEKAKLVELYRIIAYLGASLGNITQD QKLLNPNALSLHSKLSATADVMRGVLSNVHCRLCNKYHVAHVDVAYGPDTSGKDVFQKKK LGCQLLGKYKQVIGVVTQSF NT seq 603 nt NT seq  +upstreamnt  +downstreamnt atgaaggtcttggcagcaggagtcatgcccctgctgctggttctgcactggaaatatggt gcaggaagccctcttccctctgtcaacgccacctgtgccacgcgtcaccaatgtcacagc agcgtcatgagccagatcaggaaccaactggcacagctcaatagcagcgccaatgccctc tttattctctattacacagcccagggggatccattccccagcaacctggacaagttgtgc gctcccaatgtgacggacttcccggctttccatgccaatggcacggagaaggccaagctg gtggagctgtatcgcatcatcgcctaccttggtgcttccttgggcaacatcactcaggac cagaagctcctgaaccccaatgcactcagccttcatagcaagctcagtgccactgcagat gttatgcggggggtcctcagcaatgtacactgccgtctgtgcaacaagtaccacgtggca catgtggacgtggcctatggccccgacacttcaggcaaggatgtcttccagaagaagaag ctgggatgtcaactgctggggaagtacaagcaagtcattggcgtagtgactcagtccttt tag

Heterocephalus glaber (naked mole rat): 101713773 Help Entry 101713773         CDS       T02812                                  Gene name Il7 Definition (RefSeq) interleukin 7   KO K05431   interleukin 7 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04151   PI3K-Akt signaling pathway hgl04630   JAK-STAT signaling pathway hgl04640   Hematopoietic cell lineage hgl05200   Pathways in cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101713773 (Il7)    04151 PI3K-Akt signaling pathway     101713773 (Il7)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101713773 (Il7)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101713773 (Il7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101713773 (Il7)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101713773 (Il7)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101713773 (Il7) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101713773 (Il7) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101713773 (Il7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL7 Motif Other DBs NCBI-GeneID:  101713773 NCBI-ProteinID:  XP_012926714 LinkDB All DBs Position Un AA seq 251 aa AA seqDB search MTMPASRRPCSMVSAPLPGARVRAPGAPGDSGTRCRPPPPAPVLSLGRELPGPEDRGSQP LVPGRLTLAGCGETTWCPLSVPRHSAATLALLGLGSPRSGHTVSFRYIFGIPPLILVLLP VTSSNCHLKDKEGKGYENVIMISINELEKMLDIDNDCLKKEPNFFRRHSCADKKEAAFLN RAAYKLEQFVKMNITTDFELHLLKVSQGTLKLINCTKEETISKETKKNDWCFLKALIQKI KTCWNKILRGH NT seq 756 nt NT seq  +upstreamnt  +downstreamnt atgactatgcccgcctcccgcagaccatgttccatggtaagcgctcctctcccaggcgca cgagttcgcgcgcctggcgcacccggggactctgggacgcgctgccgccctcccccgccc gcccccgtcctctcccttggtcgggaactacccgggcccgaggaccgcggctcccagcct cttgtacctgggcggctgactttggcaggctgcggagaaactacctggtgcccgctttct gtcccgagacacagcgctgcaaccttggcgctgcttggccttggcagcccgcggtcaggt catacagtttcttttaggtatatctttggaattcctcccttgatccttgttctgttacca gtaacttcatctaattgtcatcttaaagataaagaaggtaaaggatatgagaatgttata atgatcagcatcaatgaattggagaaaatgctagacattgataatgattgcctgaaaaaa gaacctaacttttttaggagacattcatgtgcggataaaaaggaggctgcttttctaaat cgtgctgcttacaagttggagcaatttgttaaaatgaatatcactacggattttgagcta cacttattaaaagtttcacagggtacattaaaactgataaactgcaccaaggaagaaact atttcaaaggaaacaaaaaagaatgactggtgtttcctgaaagcactaatacaaaagatt aaaacttgttggaataaaatcttgagagggcattaa

Heterocephalus glaber (naked mole rat): 101718152 Help Entry 101718152         CDS       T02812                                  Gene name Il13 Definition (RefSeq) interleukin 13   KO K05435   interleukin 13 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway hgl04657   IL-17 signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04664   Fc epsilon RI signaling pathway hgl05200   Pathways in cancer hgl05310   Asthma hgl05321   Inflammatory bowel disease Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101718152 (Il13)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101718152 (Il13)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     101718152 (Il13)    04657 IL-17 signaling pathway     101718152 (Il13)    04664 Fc epsilon RI signaling pathway     101718152 (Il13)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101718152 (Il13)   09163 Immune disease    05310 Asthma     101718152 (Il13)    05321 Inflammatory bowel disease     101718152 (Il13)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101718152 (Il13) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101718152 (Il13) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL13 Motif Other DBs NCBI-GeneID:  101718152 NCBI-ProteinID:  XP_004836668 LinkDB All DBs Position Un AA seq 131 aa AA seqDB search MALWVTVVLALTCLSALTAPGPVPSSAALRELIEELANVTQNHKTPLCSGSMVWSVNLTA GWYCAARESLINVSSCSALQRTQKILSSLCQHRAVAKVSSFHNRDTKIEVAQFVQTLLRY LQSLYRHGNFN NT seq 396 nt NT seq  +upstreamnt  +downstreamnt atggcgctctgggtgactgtggtcctcgctctcacctgcctcagtgccctcacagccccg ggccccgtgccttcctccgcagccctcagggagctcatcgaggagctggccaacgtcacg cagaaccacaagactcccctctgcagcggcagcatggtgtggagtgtcaacctgacagct ggctggtactgtgctgcccgcgagtccctgatcaacgtctccagctgcagcgccctgcag aggacccagaagatcctgagcagtctctgccagcacagggccgtggccaaggtttccagc ttccacaaccgagacaccaaaattgaagtggcccaattcgtgcagacactgctccgatat ttacagagcctttatcgccacggaaacttcaactga

Heterocephalus glaber (naked mole rat): 101718208 Help Entry 101718208         CDS       T02812                                  Gene name Il15 Definition (RefSeq) interleukin 15   KO K05433   interleukin 15 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway hgl04668   TNF signaling pathway hgl04672   Intestinal immune network for IgA production hgl05166   Human T-cell leukemia virus 1 infection hgl05200   Pathways in cancer hgl05323   Rheumatoid arthritis Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101718208 (Il15)    04668 TNF signaling pathway     101718208 (Il15)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101718208 (Il15)  09150 Organismal Systems   09151 Immune system    04672 Intestinal immune network for IgA production     101718208 (Il15)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101718208 (Il15)   09163 Immune disease    05323 Rheumatoid arthritis     101718208 (Il15)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101718208 (Il15)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101718208 (Il15) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101718208 (Il15) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL15 Motif Other DBs NCBI-GeneID:  101718208 NCBI-ProteinID:  XP_004868951 UniProt:  A0A0P6K227 LinkDB All DBs Position Un AA seq 162 aa AA seqDB search MRISKPYLRSTSIQCYLCFLLNSHFLTEAGIHVFVLGCISAALPKTEASWHDVIHDLKRI ENLIQSIHIDATLYTESDVHPNCKITAMKCFLLELRVILHESRNVDIRETVTNVIFLANS SLSTNGNVTESGCKECEELEEKNIAEFLQSFVHIVQMFINTS NT seq 489 nt NT seq  +upstreamnt  +downstreamnt atgagaatttcgaaaccatatttgaggagtacttccatccagtgctacttgtgttttctt ctaaacagtcattttttaactgaggctggcattcacgtctttgttttgggttgtatcagt gcagctcttcctaaaacagaagccagttggcatgatgtaatacatgacttgaaaagaatt gaaaatcttattcaatctatacatattgatgctactttatatactgagagtgatgtccat cccaattgcaaaatcacagcaatgaagtgctttctcctggaattgcgagttattttacat gagtccagaaatgtggacattcgtgagacagtaaccaatgtgatcttcctggcaaatagc agtttatctactaatgggaatgtaacagaatctggatgcaaagaatgtgaggaactggag gaaaaaaatattgcagaatttctgcagagttttgtacatatagtacaaatgttcatcaac acttcttga

Heterocephalus glaber (naked mole rat): 101719419 Help Entry 101719419         CDS       T02812                                  Definition (RefSeq) interferon lambda-2   KO K22669   interferon lambda 2/3 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101719419   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101719419  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101719419 Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101719419 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL28A Motif Other DBs NCBI-GeneID:  101719419 NCBI-ProteinID:  XP_004875650 LinkDB All DBs Position Un AA seq 167 aa AA seqDB search MKPDPAGGCVLLLLLMAMVLTRTGAVPVSSALSVSSDARHCHVAQFKSLSPLELQAFKSA KDAFEERLLLKDSRCSSRLFPRAWDLRRLQVWERVVALHAELALTLEVLGSVRDPALEDV LEQPLRTLRHIHSQLRACVPAQPKAAHRPCSHRLSRWLQRLNQATKK NT seq 501 nt NT seq  +upstreamnt  +downstreamnt atgaagccagaccccgctggaggttgcgtgctgttgctgctgctgatggccatggtgctc accaggacaggggcagttcctgtctccagtgccctcagtgtctcctcagatgcgaggcac tgccacgtggcccagttcaagtctctgtccccactagagctacaggctttcaagtcagcc aaggatgcctttgaagagcggctcctgctgaaggactccaggtgcagctcgcgcctcttc cccagggcctgggacctgcggcggctgcaggtgtgggagcgcgtggtggccctgcatgct gagctcgccctgacactggaggtgctgggctccgtgagggacccagccctggaggacgtc ctggagcagcccctccgcacgctgcgtcacatccactcccagctccgggcctgtgtccca gctcagcccaaagcagcccacaggccctgcagccaccgcctgtcccgatggctgcagcgg ctcaaccaggccaccaagaag

Heterocephalus glaber (naked mole rat): 101719528 Help Entry 101719528         CDS       T02812                                  Gene name Il5 Definition (RefSeq) interleukin 5   KO K05428   interleukin 5 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway hgl04640   Hematopoietic cell lineage hgl04657   IL-17 signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04660   T cell receptor signaling pathway hgl04664   Fc epsilon RI signaling pathway hgl04672   Intestinal immune network for IgA production hgl05200   Pathways in cancer hgl05310   Asthma hgl05320   Autoimmune thyroid disease hgl05321   Inflammatory bowel disease hgl05330   Allograft rejection Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101719528 (Il5)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101719528 (Il5)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101719528 (Il5)    04660 T cell receptor signaling pathway     101719528 (Il5)    04658 Th1 and Th2 cell differentiation     101719528 (Il5)    04657 IL-17 signaling pathway     101719528 (Il5)    04664 Fc epsilon RI signaling pathway     101719528 (Il5)    04672 Intestinal immune network for IgA production     101719528 (Il5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101719528 (Il5)   09163 Immune disease    05310 Asthma     101719528 (Il5)    05320 Autoimmune thyroid disease     101719528 (Il5)    05321 Inflammatory bowel disease     101719528 (Il5)    05330 Allograft rejection     101719528 (Il5)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101719528 (Il5)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101719528 (Il5) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101719528 (Il5) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101719528 (Il5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL5 RecG_N AA_synth Motif Other DBs NCBI-GeneID:  101719528 NCBI-ProteinID:  XP_004836670 LinkDB All DBs Position Un AA seq 134 aa AA seqDB search MRVLLLWGLLALGAVNVHPSPMGSSMRTVVKETLTLLSIHQTLLIGNETLRISVPAHKNH QLCIEEIFQGINTLKNQTTQGDVLEELFQNLSLIKKHIDLQKQKCGEEQRRVKQFLDYLQ EFLTVINTEWTMEG NT seq 405 nt NT seq  +upstreamnt  +downstreamnt atgagagtgcttctgctttgggggctgctagctctgggagctgtgaatgttcatcccagc cccatgggaagttccatgaggacagtggtgaaagagaccttgactctgctttctattcat cagactctactgataggcaatgagaccctgaggatttctgttcctgcacataaaaatcac caactatgcattgaagaaatcttccagggaataaacacattgaagaatcaaaccacacaa ggggatgttttagaagaactattccaaaacttgtctttaattaaaaaacacatcgacctc caaaaacaaaaatgtggggaagaacagcggagggtaaagcagttcttagattacctgcaa gagtttcttactgtcataaatactgaatggacaatggaaggctga

Heterocephalus glaber (naked mole rat): 101720581 Help Entry 101720581         CDS       T02812                                  Gene name Il2 Definition (RefSeq) interleukin 2   KO K05429   interleukin 2 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04061   Viral protein interaction with cytokine and cytokine receptor hgl04151   PI3K-Akt signaling pathway hgl04625   C-type lectin receptor signaling pathway hgl04630   JAK-STAT signaling pathway hgl04658   Th1 and Th2 cell differentiation hgl04659   Th17 cell differentiation hgl04660   T cell receptor signaling pathway hgl04672   Intestinal immune network for IgA production hgl04940   Type I diabetes mellitus hgl05135   Yersinia infection hgl05142   Chagas disease hgl05162   Measles hgl05166   Human T-cell leukemia virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05320   Autoimmune thyroid disease hgl05321   Inflammatory bowel disease hgl05330   Allograft rejection hgl05332   Graft-versus-host disease Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101720581 (Il2)    04151 PI3K-Akt signaling pathway     101720581 (Il2)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101720581 (Il2)    04061 Viral protein interaction with cytokine and cytokine receptor     101720581 (Il2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     101720581 (Il2)    04660 T cell receptor signaling pathway     101720581 (Il2)    04658 Th1 and Th2 cell differentiation     101720581 (Il2)    04659 Th17 cell differentiation     101720581 (Il2)    04672 Intestinal immune network for IgA production     101720581 (Il2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101720581 (Il2)   09163 Immune disease    05320 Autoimmune thyroid disease     101720581 (Il2)    05321 Inflammatory bowel disease     101720581 (Il2)    05330 Allograft rejection     101720581 (Il2)    05332 Graft-versus-host disease     101720581 (Il2)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     101720581 (Il2)   09171 Infectious disease: bacterial    05135 Yersinia infection     101720581 (Il2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101720581 (Il2)    05171 Coronavirus disease - COVID-19     101720581 (Il2)    05162 Measles     101720581 (Il2)   09174 Infectious disease: parasitic    05142 Chagas disease     101720581 (Il2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101720581 (Il2)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101720581 (Il2) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101720581 (Il2) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101720581 (Il2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL2 IL15 Motif Other DBs NCBI-GeneID:  101720581 NCBI-ProteinID:  XP_004854993 LinkDB All DBs Position Un AA seq 152 aa AA seqDB search MYKMLLLSCIALTLALITSSAPTSSSTRETQEQLEQLLLDLQVILKGVTRNPKLSKMLKP KLYFPNKPSELQHLQCLEEELKVLEQVLNLAEHKHFPLINTKDFISNINVTVWKLKGSKT ALTCELNDEEANIVQFLKGWIAFCQKIISTMT NT seq 459 nt NT seq  +upstreamnt  +downstreamnt atgtacaagatgctgctcttgtcttgcattgcactaactcttgcactcatcacaagcagt gcaccaacttcaagctctacaagggaaacacaggaacaactggagcaattgctgctggat ttacaggtgattttgaaaggagttactaggaatcccaaactctccaagatgctaaaacct aaactctactttcccaataaaccctcagaattgcaacatcttcagtgcctagaagaagaa ctcaaagtcctggagcaagtgctaaatctagctgaacacaaacactttcccttgataaat accaaggatttcatcagtaatatcaacgtaacagtttggaaactaaagggatccaaaaca gcactcacgtgtgaactgaatgatgaagaagcaaacattgtacaatttctgaaaggatgg attgccttttgtcagaaaatcatctcaacaatgacttaa

Heterocephalus glaber (naked mole rat): 101720915 Help Entry 101720915         CDS       T02812                                  Gene name Il21 Definition (RefSeq) interleukin 21   KO K05434   interleukin 21 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway hgl04659   Th17 cell differentiation hgl05321   Inflammatory bowel disease Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101720915 (Il21)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101720915 (Il21)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     101720915 (Il21)  09160 Human Diseases   09163 Immune disease    05321 Inflammatory bowel disease     101720915 (Il21)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101720915 (Il21) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101720915 (Il21) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL15 Dynamin_M Motif Other DBs NCBI-GeneID:  101720915 NCBI-ProteinID:  XP_004854994 LinkDB All DBs Position Un AA seq 153 aa AA seqDB search MRSSPGNMERIVICLMVIFSGTVALKSSSQGHDGFMIRMRQLIDIVDQLKNYVNDLDPVF LPAPEDVKEHCEHSAFSCFQNATLKSASTGGNEKIINILIKQLKRKLPPSKTGRRQKHRQ TCHSCDSYEKKPPQEFLERMKLFLQKMIHQHLS NT seq 462 nt NT seq  +upstreamnt  +downstreamnt atgagatccagtcctggcaacatggaaaggatagttatctgtctgatggtcatcttctcg gggacagtggcccttaaatcaagttcccaaggacatgatggtttcatgattagaatgcgt caacttatagatattgttgatcagctgaaaaattatgtgaatgacttggatcctgtattt ttgccagctccagaagatgtaaaggaacactgtgagcactcagctttttcatgctttcag aacgctacactcaagtcagcaagtacaggaggcaatgaaaagataatcaacatattaatt aaacaattgaagaggaaactacctccctcaaagacagggagaagacagaaacacagacaa acatgccattcatgtgattcttatgagaaaaaaccaccacaagaattcctagaaagaatg aaattatttctccaaaagatgattcaccagcatctttcctag

Heterocephalus glaber (naked mole rat): 101723869 Help Entry 101723869         CDS       T02812                                  Definition (RefSeq) interferon beta-like   KO K05415   interferon beta Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04151   PI3K-Akt signaling pathway hgl04217   Necroptosis hgl04380   Osteoclast differentiation hgl04620   Toll-like receptor signaling pathway hgl04621   NOD-like receptor signaling pathway hgl04622   RIG-I-like receptor signaling pathway hgl04623   Cytosolic DNA-sensing pathway hgl04630   JAK-STAT signaling pathway hgl04650   Natural killer cell mediated cytotoxicity hgl04668   TNF signaling pathway hgl05135   Yersinia infection hgl05142   Chagas disease hgl05152   Tuberculosis hgl05160   Hepatitis C hgl05161   Hepatitis B hgl05162   Measles hgl05163   Human cytomegalovirus infection hgl05164   Influenza A hgl05165   Human papillomavirus infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05168   Herpes simplex virus 1 infection hgl05169   Epstein-Barr virus infection hgl05170   Human immunodeficiency virus 1 infection hgl05171   Coronavirus disease - COVID-19 Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101723869    04668 TNF signaling pathway     101723869    04151 PI3K-Akt signaling pathway     101723869   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101723869  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101723869  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101723869    04621 NOD-like receptor signaling pathway     101723869    04622 RIG-I-like receptor signaling pathway     101723869    04623 Cytosolic DNA-sensing pathway     101723869    04650 Natural killer cell mediated cytotoxicity     101723869   09158 Development and regeneration    04380 Osteoclast differentiation     101723869  09160 Human Diseases   09171 Infectious disease: bacterial    05135 Yersinia infection     101723869    05152 Tuberculosis     101723869   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101723869    05161 Hepatitis B     101723869    05160 Hepatitis C     101723869    05171 Coronavirus disease - COVID-19     101723869    05164 Influenza A     101723869    05162 Measles     101723869    05168 Herpes simplex virus 1 infection     101723869    05163 Human cytomegalovirus infection     101723869    05167 Kaposi sarcoma-associated herpesvirus infection     101723869    05169 Epstein-Barr virus infection     101723869    05165 Human papillomavirus infection     101723869   09174 Infectious disease: parasitic    05142 Chagas disease     101723869  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101723869 Cytokines and growth factors [BR:hgl04052]  Cytokines   Interferons    101723869 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Interferon NYD-SP28 DUF2779 GAT Motif Other DBs NCBI-GeneID:  101723869 NCBI-ProteinID:  XP_004875658 UniProt:  G5CB66 LinkDB All DBs Position Un AA seq 187 aa AA seqDB search MANRCILQIALLLSFSTISLSLSYKLLQAQQRSSSLACGELLKQLKGKPEYCLKDRMDFK FPEEIKQPQHFRKENAALVIQEMLQNILDIVRKNFSNTVWNETIVENLLVELHQQMDSLK TLLQEILEKKDITWEDTMIIPRLKGYYWRIRRHMKAKDNSICAWTVVQVELSRNFSFINR LTDYFQD NT seq 564 nt NT seq  +upstreamnt  +downstreamnt atggccaacaggtgtatcctccaaattgctctcctgttgtccttctccaccatatctctt tccttaagctacaaattgcttcaagcccaacaacgcagcagcagtttggcctgtggggag cttttgaagcagttgaaaggaaaacctgaatattgcctcaaggacaggatggatttcaaa ttccctgaggagatcaagcaaccacagcacttccggaaggagaatgctgctcttgtcatc caggagatgctccagaatatcttggatattgtcagaaaaaatttctctaacactgtatgg aatgagaccattgttgagaacctccttgttgaactccatcagcagatggacagtctgaag acactcctgcaggaaatactggagaagaaggacattacctgggaggacaccatgatcatt ccacgcctgaaggggtattattggaggatcaggaggcacatgaaggccaaggacaacagc atttgtgcctggacagtagtccaggtagaactctccaggaacttttccttcattaacaga cttacagattatttccaagactga

Heterocephalus glaber (naked mole rat): 101724943 Help Entry 101724943         CDS       T02812                                  Gene name Csf2 Definition (RefSeq) colony stimulating factor 2   KO K05427   granulocyte-macrophage colony-stimulating factor Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04630   JAK-STAT signaling pathway hgl04640   Hematopoietic cell lineage hgl04650   Natural killer cell mediated cytotoxicity hgl04657   IL-17 signaling pathway hgl04660   T cell receptor signaling pathway hgl04664   Fc epsilon RI signaling pathway hgl04668   TNF signaling pathway hgl05146   Amoebiasis hgl05166   Human T-cell leukemia virus 1 infection hgl05167   Kaposi sarcoma-associated herpesvirus infection hgl05171   Coronavirus disease - COVID-19 hgl05202   Transcriptional misregulation in cancer hgl05221   Acute myeloid leukemia hgl05323   Rheumatoid arthritis Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101724943 (Csf2)    04668 TNF signaling pathway     101724943 (Csf2)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101724943 (Csf2)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101724943 (Csf2)    04650 Natural killer cell mediated cytotoxicity     101724943 (Csf2)    04660 T cell receptor signaling pathway     101724943 (Csf2)    04657 IL-17 signaling pathway     101724943 (Csf2)    04664 Fc epsilon RI signaling pathway     101724943 (Csf2)  09160 Human Diseases   09161 Cancer: overview    05202 Transcriptional misregulation in cancer     101724943 (Csf2)   09162 Cancer: specific types    05221 Acute myeloid leukemia     101724943 (Csf2)   09163 Immune disease    05323 Rheumatoid arthritis     101724943 (Csf2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101724943 (Csf2)    05171 Coronavirus disease - COVID-19     101724943 (Csf2)    05167 Kaposi sarcoma-associated herpesvirus infection     101724943 (Csf2)   09174 Infectious disease: parasitic    05146 Amoebiasis     101724943 (Csf2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:hgl03019]     101724943 (Csf2)   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101724943 (Csf2)    00536 Glycosaminoglycan binding proteins [BR:hgl00536]     101724943 (Csf2) Messenger RNA biogenesis [BR:hgl03019]  Eukaryotic type   mRNA degradation factors    3'-5' decay     Other 3'-5' decay factors      101724943 (Csf2) Cytokines and growth factors [BR:hgl04052]  Cytokines   CSF and other factors    101724943 (Csf2) Glycosaminoglycan binding proteins [BR:hgl00536]  Heparan sulfate / Heparin   Cytokines    101724943 (Csf2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  GM_CSF Motif Other DBs NCBI-GeneID:  101724943 NCBI-ProteinID:  XP_004836687 UniProt:  G5BJ26 LinkDB All DBs Position Un AA seq 144 aa AA seqDB search MWLQNLLLLGTVVCCICAPTLPPSPVTRPWKHVDAIKEALSLLNHTSDPDAVLNETVEVV HDQFDPQEPTCLQIRLELLEKGLRGSLARLKGSLAMLASHYKQHCPPTPETSCMTQIVTF KSFKKNLKDFLFAIPFDCWKPVQK NT seq 435 nt NT seq  +upstreamnt  +downstreamnt atgtggctgcagaacctgcttctccttggcactgtggtttgttgcatctgtgcacccacc ctcccgcccagccccgtcacccggccctggaaacacgtggatgccatcaaggaagccctg agcctcctgaaccacactagtgaccctgatgctgtgctgaacgaaacagtagaagttgtc catgaccagtttgacccccaggagccgacgtgcctgcagatccgcctggagctgttagag aagggcctgcgcggcagcctggccaggctcaagggctccttggccatgctggccagccac tacaagcagcactgcccccccaccccggaaacttcctgtatgacccagattgtcaccttc aaaagtttcaaaaagaacctcaaggactttctgtttgccatcccttttgactgctggaag ccagtgcagaagtga

Heterocephalus glaber (naked mole rat): 101725985 Help Entry 101725985         CDS       T02812                                  Gene name Il19 Definition (RefSeq) interleukin 19   KO K05444   interleukin 19 Organism hgl  Heterocephalus glaber (naked mole rat) Pathway hgl04060   Cytokine-cytokine receptor interaction hgl04061   Viral protein interaction with cytokine and cytokine receptor hgl04630   JAK-STAT signaling pathway Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101725985 (Il19)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     101725985 (Il19)    04061 Viral protein interaction with cytokine and cytokine receptor     101725985 (Il19)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:hgl04052]     101725985 (Il19) Cytokines and growth factors [BR:hgl04052]  Cytokines   Interleukins    101725985 (Il19) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL10 IL22 Motif Other DBs NCBI-GeneID:  101725985 NCBI-ProteinID:  XP_004862116 LinkDB All DBs Position Un AA seq 176 aa AA seqDB search MKAQCASLWLLGTTLVLCSVHTPALRRCPLFVDMHHLEESFQEIKRAVQTKDTLQIITTL STVEILRSIKPTDVCCVTKNLLEFYMDRVFKDHQELKPQILRKISSIANSFLYMQKTLRQ CVHRRCHYSEEATHATRTVHDNYDLLEIPSAAIKSLGELDVFLAWIDRNRREADPV NT seq 531 nt NT seq  +upstreamnt  +downstreamnt atgaaggcacagtgtgcttctctctggctcctgggcaccacacttgtcctgtgctccgtg cacacccctgccctcaggaggtgcccacttttcgtggacatgcatcacctagaggagagc ttccaggaaatcaaaagagccgtgcaaaccaaggacaccctacaaatcatcaccaccctg tccacagtggagatcctgcggagcattaagcccacggatgtgtgctgcgtgaccaagaac cttctggagttctacatggacagggttttcaaggaccaccaggagctaaagcctcagatc ttgagaaaaatcagcagcattgccaactctttcctctacatgcagaaaaccctacggcaa tgcgtgcacagacggtgccactacagcgaggaagccacccatgcaaccagaactgtccat gacaactacgatttgctggagatcccttccgccgccattaagtctctgggagagctcgat gtctttctagcgtggattgacaggaatcgtcgggaagctgaccctgtctga

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