KEGG ORTHOLOGY: K05415

ORTHOLOGY: K05415

Entry

K05415                      KO

Symbol

IFNB

Name

interferon beta

Pathway

map04060

Cytokine-cytokine receptor interaction

map04151

PI3K-Akt signaling pathway

map04217

Necroptosis

map04380

Osteoclast differentiation

map04620

Toll-like receptor signaling pathway

map04621

NOD-like receptor signaling pathway

map04622

RIG-I-like receptor signaling pathway

map04623

Cytosolic DNA-sensing pathway

map04630

JAK-STAT signaling pathway

map04650

Natural killer cell mediated cytotoxicity

map04668

TNF signaling pathway

map04936

Alcoholic liver disease

map05131

Shigellosis

map05135

Yersinia infection

map05142

Chagas disease

map05152

Tuberculosis

map05160

Hepatitis C

map05161

Hepatitis B

map05162

Measles

map05163

Human cytomegalovirus infection

map05164

Influenza A

map05165

Human papillomavirus infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05168

Herpes simplex virus 1 infection

map05169

Epstein-Barr virus infection

map05170

Human immunodeficiency virus 1 infection

map05171

Coronavirus disease - COVID-19

map05417

Lipid and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05415  IFNB; interferon beta
   04668 TNF signaling pathway
    K05415  IFNB; interferon beta
   04151 PI3K-Akt signaling pathway
    K05415  IFNB; interferon beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05415  IFNB; interferon beta
09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05415  IFNB; interferon beta
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04621 NOD-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04622 RIG-I-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04623 Cytosolic DNA-sensing pathway
    K05415  IFNB; interferon beta
   04650 Natural killer cell mediated cytotoxicity
    K05415  IFNB; interferon beta
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05415  IFNB; interferon beta
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05415  IFNB; interferon beta
   05161 Hepatitis B
    K05415  IFNB; interferon beta
   05160 Hepatitis C
    K05415  IFNB; interferon beta
   05171 Coronavirus disease - COVID-19
    K05415  IFNB; interferon beta
   05164 Influenza A
    K05415  IFNB; interferon beta
   05162 Measles
    K05415  IFNB; interferon beta
   05168 Herpes simplex virus 1 infection
    K05415  IFNB; interferon beta
   05163 Human cytomegalovirus infection
    K05415  IFNB; interferon beta
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05415  IFNB; interferon beta
   05169 Epstein-Barr virus infection
    K05415  IFNB; interferon beta
   05165 Human papillomavirus infection
    K05415  IFNB; interferon beta
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K05415  IFNB; interferon beta
   05135 Yersinia infection
    K05415  IFNB; interferon beta
   05152 Tuberculosis
    K05415  IFNB; interferon beta
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K05415  IFNB; interferon beta
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K05415  IFNB; interferon beta
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K05415  IFNB; interferon beta
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05415  IFNB; interferon beta
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Interferons
   K05415  IFNB; interferon beta

Other DBs

GO:

0005132

Genes

HSA:	3456(IFNB1)

PTR:	473183(IFNB1)

PPS:	100995851(IFNB1)

GGO:	101137136(IFNB1)

PON:	100441074(IFNB1)

PPYG:

129044486(IFNB1)

NLE:	100598986(IFNB1)

HMH:	116458843(IFNB1)

SSYN:

129490755(IFNB1)

MCC:	711414(IFNB1)

MCF:	102115670(IFNB1)

MTHB:

126937702

MNI:	105465886(IFNB1)

CSAB:

103219383(IFNB1)

CATY:

105584002(IFNB1)

PANU:

101024523(IFNB1)

TGE:	112608413(IFNB1)

MLEU:

105545746(IFNB1)

RRO:	104670295(IFNB1)

RBB:	108538565(IFNB1)

TFN:	117098642(IFNB1)

PTEH:

111526147(IFNB1)

CANG:

105503452(IFNB1)

CJC:	100388391(IFNB1)

SBQ:	101035681(IFNB1)

CIMI:

108296169(IFNB1)

ANAN:

105715622(IFNB1)

CSYR:

103260915(IFNB1)

MMUR:

105874210(IFNB1)

LCAT:

123646249(IFNB1)

PCOQ:

105827006(IFNB1)

OGA:	100959385(IFNB1)

MMU:	15977(Ifnb1)

MCAL:

110293791(Ifnb1)

MPAH:

110323346(Ifnb1)

RNO:	24481(Ifnb1)

MCOC:

116095400(Ifnb1)

ANU:	117709633(Ifnb1)

ASYL:

127679947(Ifnb1)

MUN:	110541303(Ifnb1)

CGE:	103160615(Ifnb1)

MAUA:

121144026(Ifnb1)

PROB:

127224840(Ifnb1)

PLEU:

114685139(Ifnb1)

MORG:

121447990(Ifnb1)

MFOT:

126510741

AAMP:

119816165(Ifnb1) 119817276

NGI:	103743951(Ifnb1) 103746144

HGL:	101699042(Ifnb1) 101723869

CPOC:

100733284 100734449 111757491(Ifnb1)

DORD:

105988975(Ifnb1)

DSP:	122118962(Ifnb1)

PLOP:

125352673(Ifnb1)

NCAR:

124963924 124963958 124964114 124964969 124965019

MMMA:

107156465 107156489(Ifnb1)

ITI:	101968765(Ifnb1) 101971846 101975152 101975434 101975998

OCU:

100342931

OPI:	101533318(IFNB1)

TUP:	102493858(IFNB1)

GVR:	103584029 103609847 103609850

CFA:	481558(IFNB1)

CLUD:

112650215(IFNB1)

VVP:	112921940(IFNB1)

VLG:	121494639(IFNB1)

NPO:	129494739(IFNB1)

AML:	100476556(IFNB1)

UMR:	103662150(IFNB1)

UAH:	113260295(IFNB1)

UAR:	123781031(IFNB1)

ELK:

111156577

LLV:

125083789

MPUF:

101679100(IFNB1)

MNP:	132025125(IFNB1)

MLK:	131813182(IFNB1)

NVS:	122916938(IFNB1)

ORO:	101374900(IFNB1)

EJU:	114212404(IFNB1)

ZCA:	113934419(IFNB1)

MLX:	117998994(IFNB1)

NSU:	110587130(IFNB1)

LWW:	102748842(IFNB1)

FCA:	493849(IFNB1)

PYU:

121034394

PCOO:

112849621(IFNB1)

PBG:	122474874(IFNB1)

PVIV:

125150775

LRUF:

124525672

LGF:	123593203(IFNB1)

AJU:

106971145

PTG:	102960421(IFNB1)

PPAD:

109247124(IFNB1)

PUC:

125925944

PLEZ:

122205557(IFNB1)

HHV:	120239877(IFNB1)

BTA:	100848709 112441471 112441480 112447877 112447878 112447879 112447880 281845(IFNB1) 517016 525550 616977 618946(IFNB3) 784525

BOM:	102280497 102281065 102282466 102284581

BIU:	109562667 109562671 109562674 109562675 109562852 109562853 109562855

BBUB:

102402056 102402367 102402697 102408434 112583883 112583884 112583885 112583886 123332785 123465588 123465589

BBIS:

104983695 104996149 105000961(IFNB1) 105000962 105000963

CHX:	102181595 102181867 102189208 108633243 108636544 108636629 108636632 108636634

OAS:	101103376 101103623 101103702 114112819 114112830 114112835 114112840 114112883 114113004 114113016 114113206 121818657

BTAX:

128052625 128052626 128052627 128052628 128052635 128052636 128052637 128052638 128052639 128052640 128052652

CSUM:

138081397(IFNB1) 138081398 138081399 138081400 138081401 138081410 138081421 138081422 138081423 138081424 138081425 138081426 138081433 138081525

ODA:	120860069 120860132 120860137 120862218 120862226 120862257

CCAD:

122453394 122453395 122453396 122453397 122453398 122453400

MREE:

136148258 136148259 136148388 136148389 136148420 136148421 136148422 136148545 136148546 136148694 136148695 136148697 136148700

OVR:	110122125 110122128 110122129 110122130 139039428 139039507

MBEZ:

129557110 129557288 129557307 129557308

SSC:	445459(IFNB1)

CFR:	102513411(IFNB1)

CBAI:

105061881(IFNB1)

CDK:	105095933(IFNB1)

VPC:	102540243(IFNB1)

BACU:

103011926

BMUS:

118897323(IFNB1)

LVE:

103073772

OOR:	101289058(IFNB1)

LALB:

132522916(IFNB1)

DLE:	111174560(IFNB1)

PCAD:

102990155(IFNB1)

PSIU:

116755914(IFNB1)

NASI:

112407026(IFNB1)

ECB:	100052545(IFNB1) 100052658 100147174

EPZ:	103563147 103563148(IFNB1) 103563150

EAI:	106828272 106834164 106834179 106834202 123280255 123280293

MYB:	102261905(IFNB1)

MYD:	102765800(IFNB1)

MMYO:

118666805(IFNB1)

MLF:	102417209(IFNB1)

MDT:	132212752(IFNB1)

MYUM:

139020554(IFNB1)

PKL:	118716770(IFNB1)

EFUS:

103289195(IFNB1)

MNA:	107531433(IFNB1)

DRO:	112300024(IFNB1)

SHON:

118997987 118997988 118997989 118997990

AJM:	119055662(IFNB1)

PDIC:

114512515(IFNB1)

PHAS:

123820149 123820232(IFNB1)

MMF:	118629329(IFNB1)

PPAM:

129078454(IFNB1)

HAI:	109396418(IFNB1)

RFQ:	117032413(IFNB1)

PALE:

102890512(IFNB1)

PGIG:

120605473(IFNB1)

PVP:	105309141(IFNB1)

RAY:	107518589(IFNB1)

MJV:	108402531(IFNB1)

TOD:	119231101(IFNB1)

SARA:

101548268(IFNB1)

SFUM:

130026530(IFNB1)

SETR:

126002675(IFNB1)

LAV:	100666438(IFNB1)

TMU:

101349610

ETF:	101650550(IFNB1)

DNM:	101410923(IFNB1)

MDO:	100021258(IFNB1)

GAS:

123250431

SHR:

100914443

AFZ:

127552925

PCW:	110199211 110199212 110199213 110199216 110199218

TVP:	118834723 118834733 118836026 118836153 118836347 118840459 118849866

PBRV:

138161235 138161237

OAA:	100082925(IFNB1)

TACU:

119949108

GGA:	554219(IFNW1)

MGP:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

106045178 125180135 125180136 136788419 136788956 136788957 136788988 136788998 136788999 136789085 136789086 136789087 136789088

CATA:

118257698 118257699 118257700 118257701 118257702 118257703 118257704 126913675 126913676

AFUL:

116500389 116500390 116500391 116500392 116501035

LSR:

SCAN:

OTC:

PRUF:

ATRC:

139588754 139589349 139589350 139589352 139589353 139589354 139589355 139589356 139589357 139589358 139589359 139589360 139589361 139589363

OMA:	130265549 130265550

CBRC:

108449705

ZAB:

102066024

ZLE:	135459301 135459312 135459314 135459315 135459316 135459317 135459318 135459319 135459544 135459642 135459800 135459801

ACHL:

103802741

SVG:

106865001

MMEA:

130573264 130575640

HRT:	120765091 120765092 120765093 120765094 120765095

SATI:

136373436 136373684 136373696 136373709 136373746

CCIC:

134056592 134056593 134056595 134056596 134056599 134056602 134056604 134056605 134056606 134056608 134056609 134056610 134056611 134056612 134056618 134056619 134056620 134056621

FPG:

101921672

NNT:

104400091

SHAB:

115619468 115619469 115619470 115619471

TALA:

122153561

ACHC:

115337094 115337096 115337097

HLE:

104827847

HHAR:

128137198 128137206 128137208 128137209 128137210 128137213 128137216 128137217 128137218 128137232 128137240

GCL:	127027303 127027304 127027305 127027306

LDI:

104350945

MNB:

103781025

PPUS:

135173522 135173563 135173564 135193079 135193110 135193182 135193225 135193251

NNI:

PCAO:

AFOR:

FGA:

MUI:

EHS:

CMAC:

CUCA:

ACAR:

CPEA:

CVF:

RTD:

AROW:

SCAM:

TVC:

Reference

PMID:16593086

Authors

Ohno S, Taniguchi T

Title

Structure of a chromosomal gene for human interferon beta.

Journal

Proc Natl Acad Sci U S A 78:5305-9 (1981)
DOI:10.1073/pnas.78.9.5305

Sequence

[hsa:3456]

LinkDB

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