Homo sapiens (human): 2209
Entry
2209 CDS
T01001
Gene name
FCGR1A, CD64, CD64A, FCRI, IGFR1
Definition
(RefSeq) Fc fragment of IgG receptor Ia
KO
K06498
high affinity immunoglobulin gamma Fc receptor I
Organism
hsa
Homo sapiens (human)
Pathway
hsa04145
Phagosome
hsa04380
Osteoclast differentiation
hsa04640
Hematopoietic cell lineage
hsa04666
Fc gamma R-mediated phagocytosis
hsa05140
Leishmaniasis
hsa05150
Staphylococcus aureus infection
hsa05152
Tuberculosis
hsa05202
Transcriptional misregulation in cancer
hsa05221
Acute myeloid leukemia
hsa05322
Systemic lupus erythematosus
Network
nt06240
Transcription
nt06275
Acute myeloid leukemia
Element
N00112
AML1-ETO fusion to PU.1-mediated transcription
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
2209 (FCGR1A)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
2209 (FCGR1A)
04666 Fc gamma R-mediated phagocytosis
2209 (FCGR1A)
09158 Development and regeneration
04380 Osteoclast differentiation
2209 (FCGR1A)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
2209 (FCGR1A)
09162 Cancer: specific types
05221 Acute myeloid leukemia
2209 (FCGR1A)
09163 Immune disease
05322 Systemic lupus erythematosus
2209 (FCGR1A)
09171 Infectious disease: bacterial
05150 Staphylococcus aureus infection
2209 (FCGR1A)
05152 Tuberculosis
2209 (FCGR1A)
09174 Infectious disease: parasitic
05140 Leishmaniasis
2209 (FCGR1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
2209 (FCGR1A)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hsa04090
]
2209 (FCGR1A)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Phagocytosis
Fc receptors
2209 (FCGR1A)
CD molecules [BR:
hsa04090
]
Proteins
2209 (FCGR1A)
SSDB
Motif
Pfam:
Ig_2
Ig_3
ig
V-set
I-set
Ig_4
PIRT
Adeno_E3_CR1
SID-1_RNA_chan
Other DBs
NCBI-GeneID:
2209
NCBI-ProteinID:
NP_000557
OMIM:
146760
HGNC:
3613
Ensembl:
ENSG00000150337
Vega:
OTTHUMG00000012089
Pharos:
P12314
(Tchem)
UniProt:
P12314
LinkDB
Structure
PDB:
4ZNE
3RJD
Position
1q21.2
AA seq
374 aa
MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG
TATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPL
ALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAG
ISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRN
TSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVG
IMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQ
LQEGVHRKEPQGAT
NT seq
1125 nt
+upstream
nt +downstream
nt
atgtggttcttgacaactctgctcctttgggttccagttgatgggcaagtggacaccaca
aaggcagtgatcactttgcagcctccatgggtcagcgtgttccaagaggaaaccgtaacc
ttgcactgtgaggtgctccatctgcctgggagcagctctacacagtggtttctcaatggc
acagccactcagacctcgacccccagctacagaatcacctctgccagtgtcaatgacagt
ggtgaatacaggtgccagagaggtctctcagggcgaagtgaccccatacagctggaaatc
cacagaggctggctactactgcaggtctccagcagagtcttcacggaaggagaacctctg
gccttgaggtgtcatgcgtggaaggataagctggtgtacaatgtgctttactatcgaaat
ggcaaagcctttaagtttttccactggaattctaacctcaccattctgaaaaccaacata
agtcacaatggcacctaccattgctcaggcatgggaaagcatcgctacacatcagcagga
atatctgtcactgtgaaagagctatttccagctccagtgctgaatgcatctgtgacatcc
ccactcctggaggggaatctggtcaccctgagctgtgaaacaaagttgctcttgcagagg
cctggtttgcagctttacttctccttctacatgggcagcaagaccctgcgaggcaggaac
acatcctctgaataccaaatactaactgctagaagagaagactctgggttatactggtgc
gaggctgccacagaggatggaaatgtccttaagcgcagccctgagttggagcttcaagtg
cttggcctccagttaccaactcctgtctggtttcatgtccttttctatctggcagtggga
ataatgtttttagtgaacactgttctctgggtgacaatacgtaaagaactgaaaagaaag
aaaaagtgggatttagaaatctctttggattctggtcatgagaagaaggtaatttccagc
cttcaagaagacagacatttagaagaagagctgaaatgtcaggaacaaaaagaagaacag
ctgcaggaaggggtgcaccggaaggagccccagggggccacgtag
DBGET
integrated database retrieval system
