Homo sapiens (human): 284098
Entry
284098 CDS
T01001
Gene name
PIGW, Gwt1, HPMRS5
Definition
(RefSeq) phosphatidylinositol glycan anchor biosynthesis class W
KO
K05283
glucosaminylphosphatidylinositol acyltransferase [EC:2.3.-.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00563
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
hsa01100
Metabolic pathways
Module
hsa_M00065
GPI-anchor biosynthesis, core oligosaccharide
Network
nt06018
GPI-anchor biosynthesis
Element
N00748
GPI-anchor biosynthesis
N00749
PGAP1 deficiency in GPI-anchor biosynthesis
N00750
PIGT deficiency in GPI-anchor biosynthesis
N00751
PIGO deficiency in GPI-anchor biosynthesis
N00752
PIGN deficiency in GPI-anchor biosynthesis
N00753
PIGV deficiency in GPI-anchor biosynthesis
N00754
PIGM deficiency in GPI-anchor biosynthesis
N00755
PIGW deficiency in GPI-anchor biosynthesis
Disease
H01488
Hyperphosphatasia with mental retardation syndrome
H01489
Inherited glycosylphosphatidylinositol deficiencies
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
284098 (PIGW)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.- Acyltransferases
2.3.-.-
284098 (PIGW)
SSDB
Motif
Pfam:
GWT1
Baculo_11_kDa
Other DBs
NCBI-GeneID:
284098
NCBI-ProteinID:
NP_001333683
OMIM:
610275
HGNC:
23213
Ensembl:
ENSG00000277161
Vega:
OTTHUMG00000188438
Pharos:
Q7Z7B1
(Tdark)
UniProt:
Q7Z7B1
LinkDB
Position
17q12
AA seq
504 aa
MSEKQMKEAFVSNLNGTTVLEITQGLCFPAFCILCRGFLIIFSQYLCSFSPTWKTRFLTD
FVVLIVPMVATLTIWASFILLELLGVIIFGAGLLYQIYRRRTCYARLPFLKILEKFLNIS
LESEYNPAISCFRVITSAFTAIAILAVDFPLFPRRFAKTELYGTGAMDFGVGGFVFGSAM
VCLEVRRRKYMEGSKLHYFTNSLYSVWPLVFLGIGRLAIIKSIGYQEHLTEYGVHWNFFF
TIIVVKLITPLLLIIFPLNKSWIIALGITVLYQLALDFTSLKRLILYGTDGSGTRVGLLN
ANREGIISTLGYVAIHMAGVQTGLYMHKNRSHIKDLIKVACFLLLAAISLFISLYVVQVN
VEAVSRRMANLAFCIWIVASSLILLSSLLLGDIILSFAKFLIKGALVPCSWKLIQSPVTN
KKHSESLVPEAERMEPSLCLITALNRKQLIFFLLSNITTGLINLMVDTLHSSTLWALFVV
NLYMFSNCLIVYVLYLQDKTVQFW
NT seq
1515 nt
+upstream
nt +downstream
nt
atgtctgaaaagcagatgaaggaagcttttgtcagtaacctcaatggaaccaccgtgctg
gaaatcacccagggattgtgctttcctgcattctgtatcctgtgcagagggttcctgatc
attttctcacagtacttgtgttctttttcacctacctggaaaactagattcctcactgac
tttgttgtcctaatagttcccatggtagccactttgaccatttgggcttcatttatcctc
cttgagcttctcggtgtaattatctttggggcagggctgttgtatcaaatataccgaagg
aggacctgctatgccagactgcctttcctaaaaatccttgaaaaattcttgaacatcagt
ctagaatcagaatacaatccagccatctcctgtttccgtgtaattaccagtgcgtttact
gctattgctattttggctgtggacttcccactttttcccagaagatttgccaaaactgag
ctctatgggacaggagcaatggattttggagtaggtggctttgtttttgggtctgcaatg
gtttgtctagaggtcaggaggagaaaatatatggaagggtccaaattgcattactttaca
aactcattgtactctgtttggccattagtcttcctaggaatcggacgattagccattata
aaatcaataggctatcaggaacatttaacagagtatggagttcactggaactttttcttt
accataatagttgtgaaattgataacaccactgctgttgattatttttcccctaaataag
tcctggattattgccctcggcattactgtattataccagctagcccttgactttacctca
ctgaagaggttaatattatatggcactgatggtagtggcacacgggttggtctattaaat
gccaaccgcgaaggaataatctctaccctggggtatgtggcaatacacatggctggtgtg
caaacagggttatatatgcataagaaccgatcacatatcaaagacttgataaaagtagcc
tgttttcttttactggcagctattagcctcttcatatctctttacgtagttcaagtaaat
gtagaagcagtatctcgaagaatggcaaatttagccttttgtatttggatagttgcttct
agcctgatccttcttagtagtttattactgggtgatataattttgagttttgccaaattt
ctaattaaaggagctctagtaccatgttcttggaaacttatccagtcacctgttacaaat
aaaaagcattcagaatctctagtccctgaagccgaaagaatggaacccagtctttgttta
atcacagctctaaacagaaaacagttaatatttttcttgctgtcaaatataacaactggc
ctgatcaacctgatggtagatacattacacagcagtaccttgtgggccttatttgtggtc
aatctctatatgttttccaactgtttaattgtatatgtactatatttgcaagataagact
gtacaattttggtga
DBGET
integrated database retrieval system
