Homo sapiens (human): 8833 Help Entry 8833              CDS       T01001                                  Gene name GMPS, GATD7 Definition (RefSeq) guanine monophosphate synthase   KO K01951   GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] Organism hsa  Homo sapiens (human) Pathway hsa00230   Purine metabolism hsa00983   Drug metabolism - other enzymes hsa01100   Metabolic pathways Module hsa_M00050   Guanine ribonucleotide biosynthesis IMP => GDP,GTP Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     8833 (GMPS)   09111 Xenobiotics biodegradation and metabolism    00983 Drug metabolism - other enzymes     8833 (GMPS)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     8833 (GMPS) Enzymes [BR:hsa01000]  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor     6.3.5.2  GMP synthase (glutamine-hydrolysing)      8833 (GMPS) Peptidases and inhibitors [BR:hsa01002]  Cysteine peptidases   Family C26: gamma-glutamyl hydrolase family    8833 (GMPS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  GATase GMP_synt_C NAD_synthase Peptidase_C26 QueC tRNA_Me_trans ATP_bind_3 Asn_synthase PAPS_reduct ThiI Arginosuc_synth Pyr_redox_2 Motif Other DBs NCBI-GeneID:  8833 NCBI-ProteinID:  NP_003866 OMIM:  600358 HGNC:  4378 Ensembl:  ENSG00000163655 Vega:  OTTHUMG00000158551 Pharos:  P49915(Tbio) UniProt:  P49915 A0A140VJK6 LinkDB All DBs Structure PDB:  2VPI 2VXO Thumbnails Position 3q25.31 AA seq 693 aa AA seqDB search MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETP AFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHK KSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANE SKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVL VLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAA HSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLKPE EVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVR ILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPH TLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDW ESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILR ESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVE VVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE NT seq 2082 nt NT seq  +upstreamnt  +downstreamnt atggctctgtgcaacggagactccaagctggagaatgctggaggagaccttaaggatggc caccaccactatgaaggagctgttgtcattctggatgctggtgctcagtacgggaaagtc atagaccgaagagtgagggaactgttcgtgcagtctgaaattttccccttggaaacacca gcatttgctataaaggaacaaggattccgtgctattatcatctctggaggacctaattct gtgtatgctgaagatgctccctggtttgatccagcaatattcactattggcaagcctgtt cttggaatttgctatggtatgcagatgatgaataaggtatttggaggtactgtgcacaaa aaaagtgtcagagaagatggagttttcaacattagtgtggataatacatgttcattattc aggggccttcagaaggaagaagttgttttgcttacacatggagatagtgtagacaaagta gctgatggattcaaggttgtggcacgttctggaaacatagtagcaggcatagcaaatgaa tctaaaaagttatatggagcacagttccaccctgaagttggccttacagaaaatggaaaa gtaatactgaagaatttcctttatgatatagctggatgcagtggaaccttcaccgtgcag aacagagaacttgagtgtattcgagagatcaaagagagagtaggcacgtcaaaagttttg gttttactcagtggtggagtagactcaacagtttgtacagctttgctaaatcgtgctttg aaccaagaacaagtcattgctgtgcacattgataatggctttatgagaaaacgagaaagc cagtctgttgaagaggccctcaaaaagcttggaattcaggtcaaagtgataaatgctgct cattctttctacaatggaacaacaaccctaccaatatcagatgaagatagaaccccacgg aaaagaattagcaaaacgttaaatatgaccacaagtcctgaagagaaaagaaaaatcatt ggggatacttttgttaagattgccaatgaagtaattggagaaatgaacttgaaaccagag gaggttttccttgcccaaggtactttacggcctgatctaattgaaagtgcatcccttgtt gcaagtggcaaagctgaactcatcaaaacccatcacaatgacacagagctcatcagaaag ttgagagaggagggaaaagtaatagaacctctgaaagattttcataaagatgaagtgaga attttgggcagagaacttggacttccagaagagttagtttccaggcatccatttccaggt cctggcctggcaatcagagtaatatgtgctgaagaaccttatatttgtaaggactttcct gaaaccaacaatattttgaaaatagtagctgatttttctgcaagtgttaaaaagccacat accctattacagagagtcaaagcctgcacaacagaagaggatcaggagaagctgatgcaa attaccagtctgcattcactgaatgccttcttgctgccaattaaaactgtaggtgtgcag ggtgactgtcgttcctacagttacgtgtgtggaatctccagtaaagatgaacctgactgg gaatcacttatttttctggctaggcttatacctcgcatgtgtcacaacgttaacagagtt gtttatatatttggcccaccagttaaagaacctcctacagatgttactcccactttcttg acaacaggggtgctcagtactttacgccaagctgattttgaggcccataacattctcagg gagtctgggtatgctgggaaaatcagccagatgccggtgattttgacaccattacatttt gatcgggacccacttcaaaagcagccttcatgccagagatctgtggttattcgaaccttt attactagtgacttcatgactggtatacctgcaacacctggcaatgagatccctgtagag gtggtattaaagatggtcactgagattaagaagattcctggtatttctcgaattatgtat gacttaacatcaaagcccccaggaactactgagtgggagtaa

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