NRAS  NRAS proto-oncogene, GTPase [KO:K07828]

hsa_var Human gene variants (Homo sapiens)

mutation G13V
ClinVar: 375876
dbSNP: rs121434596
COSM: 574

mutation G13D
ClinVar: 13901
dbSNP: rs121434596
COSM: 573

mutation Q61R
ClinVar: 13900 375873 376220
dbSNP: rs11554290 rs1057519695 rs1057519834
COSM: 584

mutation Q61H
ClinVar: 375871 373003
dbSNP: rs12193255 rs12193255

mutation G12D
ClinVar: 39648
dbSNP: rs12193237
COSM:564

mutation Q61K
ClinVar: 73058
dbSNP: rs121913254
COSM:580

mutation Q61L
ClinVar: 375872 375874
dbSNP: rs1057519695 rs11554290

mutation G12S
ClinVar: 177778
dbSNP: rs121913250
COSM: 563

mutation G13S
ClinVar: 376221
dbSNP: rs121434595
COSM: 571

PMID:3103719

Bos JL, Verlaan-de Vries M, van der Eb AJ, Janssen JW, Delwel R, Lowenberg B, Colly LP

Mutations in N-ras predominate in acute myeloid leukemia.

Blood 69:1237-41 (1987)

PMID:2674680

van 't Veer LJ, Burgering BM, Versteeg R, Boot AJ, Ruiter DJ, Osanto S, Schrier PI, Bos JL

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

Mol Cell Biol 9:3114-6 (1989)
DOI:10.1128/MCB.9.7.3114

PMID:14695152

Omholt K, Platz A, Kanter L, Ringborg U, Hansson J.

NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.

Clin Cancer Res 9:6483-8 (2003)

PMID:24774510

Takahashi N, Yamada Y, Taniguchi H, Fukahori M, Sasaki Y, Shoji H, Honma Y, Iwasa S, Takashima A, Kato K, Hamaguchi T, Shimada Y

Clinicopathological features and prognostic roles of KRAS, BRAF, PIK3CA and NRAS mutations in advanced gastric cancer.

BMC Res Notes 7:271 (2014)
DOI:10.1186/1756-0500-7-271