KEGG   ORTHOLOGY: K02273
Entry
K02273                      KO                                     
Symbol
COX8
Name
cytochrome c oxidase subunit 8
Pathway
map00190  Oxidative phosphorylation
map01100  Metabolic pathways
map04260  Cardiac muscle contraction
map04714  Thermogenesis
map04932  Non-alcoholic fatty liver disease
map05010  Alzheimer disease
map05012  Parkinson disease
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05208  Chemical carcinogenesis - reactive oxygen species
map05415  Diabetic cardiomyopathy
Module
M00154  Cytochrome c oxidase
Disease
H01368  Cytochrome c oxidase (COX) deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K02273  COX8; cytochrome c oxidase subunit 8
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K02273  COX8; cytochrome c oxidase subunit 8
  09159 Environmental adaptation
   04714 Thermogenesis
    K02273  COX8; cytochrome c oxidase subunit 8
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K02273  COX8; cytochrome c oxidase subunit 8
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02273  COX8; cytochrome c oxidase subunit 8
   05012 Parkinson disease
    K02273  COX8; cytochrome c oxidase subunit 8
   05014 Amyotrophic lateral sclerosis
    K02273  COX8; cytochrome c oxidase subunit 8
   05016 Huntington disease
    K02273  COX8; cytochrome c oxidase subunit 8
   05020 Prion disease
    K02273  COX8; cytochrome c oxidase subunit 8
   05022 Pathways of neurodegeneration - multiple diseases
    K02273  COX8; cytochrome c oxidase subunit 8
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K02273  COX8; cytochrome c oxidase subunit 8
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K02273  COX8; cytochrome c oxidase subunit 8
Other DBs
TC: 3.D.4.11
Genes
HSA: 1351(COX8A) 341947(COX8C)
PTR: 100608033 742828(COX8A)
PPS: 100984553 103783322
GGO: 101140105 101144277
PON: 100172325(COX8A) 100450286
NLE: 115832449 115833541 115834767
MCC: 106993150 106996000 718007(COX8A)
MCF: 102122063 102139510
CSAB: 103229590(COX8C)
CATY: 105577509 105596604
PANU: 100126727(COX8A) 101026809
CJC: 100385011(COX8C) 100408082(COX8A)
CSYR: 110594887
MMUR: 109730635
OGA: 111728090
MMU: 12868(Cox8a) 12869(Cox8b) 75483(Cox8c)
RNO: 171335(Cox8a) 25250(Cox8b) 360229(Cox8c)
NCAR: 124959872
CFA: 106558390 476040(COX8A)
AML: 100475627
FCA: 101096603
PYU: 121023724
PBG: 122483938
PTG: 102960097
PPAD: 109246642
AJU: 106981758
HHV: 120249178
BTA: 100300759 281091(COX8A) 615757(COX8B) 783202
BOM: 102279352
BIU: 109554587
CHX: 102188021
OAS: 106991840
CFR: 116666513
CBAI: 105064513
CDK: 116152083
VPC: 116285480
LVE: 103087636
OOR: 105748355
MMYO: 118665381
MLF: 102434465
MNA: 107539792
HAI: 109384184
DRO: 112317280
AJM: 119045463
PDIC: 114500670
PHAS: 123829465
RFQ: 117030626
PALE: 102882053
PVP: 105297836
RAY: 107497080
MJV: 108385868
TOD: 119250116
LAV: 100665257
TMU: 111821885
DNM: 101435760
GAS: 123254220
PCW: 110223582
GGA: 775974(COX8A)
NMEL: 110391373
ASN: 102373396
AMJ: 102574710
PSS: 106732988
BGAR: 122920761
DRE: 100330915(si:dkey-85n7.8) 557348(cox8a) 569770(cox8b)
PPRM: 120468315 120493472(si:dkey-85n7.8) 120494650
IPU: 108257834(si:dkey-85n7.8) 108268664 108278570
SMEO: 124376578(si:dkey-85n7.8) 124386110 124397996
TFD: 113643348(si:dkey-85n7.8) 113648835 113651907
TRU: 101063036
NCC: 104948574
CGOB: 115027455
ELY: 117261898 117266834 117270290(si:dkey-85n7.8)
SLUC: 116040179 116061004(si:dkey-85n7.8) 116065792
ECRA: 117935508 117941270(si:dkey-85n7.8) 117948783
GAT: 120814267(si:dkey-85n7.8) 120832870
PPUG: 119227749(si:dkey-85n7.8)
CUD: 121514777 121520897(si:dkey-85n7.8) 121526765
ALAT: 119004422(si:dkey-85n7.8) 119025111 119034484
MZE: 112436572
ONL: 106096937
OAU: 116334832(si:dkey-85n7.8) 116335552 120440457
XMA: 106700490
XCO: 114134483
XHE: 116709329
GAF: 122825307(si:dkey-85n7.8) 122846541
CVG: 107081684
ALIM: 106521225
NWH: 119416062 119427174 119427716(si:dkey-85n7.8)
CSEM: 103387892
POV: 109627835
SDU: 111225849
XGL: 120789255(si:dkey-85n7.8) 120792699 120794985
HCQ: 109527112
BPEC: 110155668
MALB: 109971983
BSPL: 114848515
SASA: 106561622(COX81) 106563661 106571735 106573095(COX81) 106602990(COX81)
OMY: 110509437 110524599 110529740(si:dkey-85n7.8) 110534122
PKI: 111850681
LOC: 107075769
PSPA: 121294775 121329491(si:dkey-85n7.8)
CMK: 103171903
DME: Dmel_CG7181(COX8)
DER: 6543885
DSI: Dsimw501_GD12109(Dsim_CoVIII)
DSR: 110190253
DPE: 6603331
DMN: 108153066
DWI: 6642924
DGR: 6557019
DAZ: 108612578
DNV: 115564179
DHE: 111605740
CCAT: 101458255
BOD: 106616903
SCAC: 106095355
LCQ: 111682741
LSQ: 119604316
HIS: 119652590
ACOZ: 120950100
AARA: 120908497
BBIF: 117211869
BVK: 117233278
BVAN: 117160088
CCIN: 107265725
TCA: 107398271
ATD: 109595792
LDC: 111517597
BMOR: 101741939
BMAN: 114246649
OFU: 114353239
PXY: 105385018
DCI: 108252800
TSP: Tsp_04417
 » show all
Reference
PMID:2543673
  Authors
Rizzuto R, Nakase H, Darras B, Francke U, Fabrizi GM, Mengel T, Walsh F, Kadenbach B, DiMauro S, Schon EA
  Title
A gene specifying subunit VIII of human cytochrome c oxidase is localized to chromosome 11 and is expressed in both muscle and non-muscle tissues.
  Journal
J Biol Chem 264:10595-600 (1989)
  Sequence
[hsa:1351]
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