KEGG ORTHOLOGY: K07890

ORTHOLOGY: K07890

Entry

K07890                      KO

Symbol

RAB21

Name

Ras-related protein Rab-21

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07890  RAB21; Ras-related protein Rab-21
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07890  RAB21; Ras-related protein Rab-21
   04031 GTP-binding proteins
    K07890  RAB21; Ras-related protein Rab-21
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Rab GTPases and associated proteins
   Rab GTPases
    K07890  RAB21; Ras-related protein Rab-21
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07890  RAB21; Ras-related protein Rab-21
  Exosomal proteins of other body fluids (saliva and urine)
   K07890  RAB21; Ras-related protein Rab-21
GTP-binding proteins [BR:ko04031]
Small (monomeric) G-proteins
  Rab Family
   Rab20/21/24 [OT]
    K07890  RAB21; Ras-related protein Rab-21

Genes

HSA:	23011(RAB21)

PTR:	467069(RAB21)

PPS:	100978907(RAB21)

GGO:	101148751(RAB21)

PON:	100461167(RAB21)

PPYG:

129010867(RAB21)

NLE:	100586791(RAB21)

HMH:	116479017(RAB21)

SSYN:

129459227(RAB21)

MCC:	718715(RAB21)

MCF:	102133663(RAB21)

MTHB:

126931819

MNI:	105473367(RAB21)

CSAB:

103238727(RAB21)

CATY:

105581031(RAB21)

PANU:

101000066(RAB21)

TGE:	112634932(RAB21)

MLEU:

105538612(RAB21)

RRO:	104668099(RAB21)

RBB:	108526663(RAB21)

TFN:	117089735(RAB21)

PTEH:

111552350(RAB21)

CANG:

105502693(RAB21)

CJC:	100401527(RAB21)

SBQ:	101036210(RAB21)

CIMI:

108290288(RAB21)

ANAN:

105709496(RAB21)

CSYR:

103257540(RAB21)

MMUR:

105856886(RAB21)

LCAT:

123639510(RAB21)

PCOQ:

105808421(RAB21)

OGA:	100956953(RAB21)

MMU:	216344(Rab21)

MCAL:

110303879(Rab21)

MPAH:

110326508(Rab21)

RNO:	299799(Rab21)

MCOC:

116075841(Rab21)

ANU:	117696334(Rab21)

ASYL:

127671067(Rab21)

MUN:	110553080(Rab21)

CGE:	100762794(Rab21)

MAUA:

101829825(Rab21)

PROB:

127215746(Rab21)

PLEU:

114699045(Rab21)

MORG:

121459095(Rab21)

MFOT:

126497448

AAMP:

119803526(Rab21)

NGI:	103735341(Rab21)

HGL:	101722646(Rab21)

CPOC:

100718613(Rab21)

CCAN:

109696103(Rab21)

DORD:

105987408(Rab21)

DSP:	122124068(Rab21)

PLOP:

125361152(Rab21)

NCAR:

124983168

MMMA:

107140053(Rab21)

ITI:	101969126(Rab21)

OCU:

100344142

OPI:	101528864(RAB21)

TUP:	102487638(RAB21)

GVR:	103605983(RAB21)

CFA:	100683312(RAB21)

CLUD:

112677844(RAB21)

VVP:	112922181(RAB21)

VLG:	121491002(RAB21)

NPO:	129511788(RAB21)

AML:	100473681(RAB21)

UMR:	103656978(RAB21)

UAH:	113256265(RAB21)

UAR:	123787122(RAB21)

ELK:

111142116

LLV:

125106457

MPUF:

101679848(RAB21)

MNP:	132019411(RAB21)

MLK:	131839170(RAB21)

NVS:	122892597(RAB21)

ORO:	101369036(RAB21)

EJU:	114214986(RAB21)

ZCA:	113921799(RAB21)

MLX:	118008560(RAB21)

NSU:	110570601(RAB21)

LWW:	102745384(RAB21)

FCA:	101081478(RAB21)

PYU:	121040739(RAB21)

PCOO:

112863944(RAB21)

PBG:	122474065(RAB21)

PVIV:

125170261(RAB21)

LRUF:

124501105 124504325

LGF:	123592154(RAB21)

AJU:

106967382

PTG:	102957038(RAB21)

PPAD:

109270518(RAB21)

PUC:

125919349

PLEZ:

122224838(RAB21)

HHV:	120223356(RAB21)

BTA:	507488(RAB21) 781001

BOM:	102277684(RAB21)

BIU:

109554896

BBUB:

102395444(RAB21)

BBIS:

104989311(RAB21) 105001875

CHX:	102176098(RAB21)

OAS:	100302077(RAB21)

BTAX:

128046921 128047883(RAB21)

CSUM:

138078202(RAB21)

ODA:	120857961(RAB21)

CCAD:

122427083(RAB21)

MREE:

136166991(RAB21)

OVR:	110146284(RAB21)

MBEZ:

129535601(RAB21)

SSC:	100736618(RAB21)

CFR:	102516573(RAB21)

CBAI:

105072047(RAB21)

CDK:	105095996(RAB21)

VPC:	102537510(RAB21)

BACU:

103007649(RAB21)

BMUS:

118901942(RAB21)

LVE:	103088685(RAB21)

OOR:	101270577(RAB21)

LALB:

132529067(RAB21)

DLE:	111173736(RAB21)

PCAD:

102996717(RAB21)

PSIU:

116760086(RAB21)

NASI:

112394237(RAB21)

ECB:	100056811(RAB21)

EPZ:	103561951(RAB21)

EAI:	106826106(RAB21)

MYB:	102257490(RAB21)

MYD:	102756123 102760040(RAB21)

MMYO:

118649638(RAB21)

MLF:	102417108(RAB21)

MDT:	132227944(RAB21)

MYUM:

139006900(RAB21)

PKL:	118728254(RAB21)

EFUS:

103298767(RAB21)

MNA:	107526496(RAB21)

DRO:	112319055(RAB21)

SHON:

118989341(RAB21)

AJM:	119060858(RAB21)

PDIC:

114512828(RAB21)

PHAS:

123812385(RAB21)

MMF:	118623552(RAB21)

PPAM:

129075892(RAB21)

HAI:	109387698(RAB21)

RFQ:	117028378(RAB21)

PALE:

102890846(RAB21)

PGIG:

120605076(RAB21)

PVP:	105301614(RAB21)

MJV:	108408165(RAB21)

TOD:	119247503(RAB21)

SARA:

101544660(RAB21)

SFUM:

130038856(RAB21)

SETR:

126021895(RAB21)

LAV:	100669626(RAB21)

TMU:

101354787

ETF:	101653431(RAB21)

DNM:	101411166(RAB21)

MDO:	100016635(RAB21)

GAS:	123250173(RAB21)

SHR:	100922068(RAB21)

AFZ:

127564313

PCW:	110195926(RAB21)

TVP:	118850222(RAB21)

PBRV:

138156573(RAB21)

OAA:	100087487(RAB21)

TACU:

119936697(RAB21)

GGA:	771383(RAB21)

PCOC:

116226751(RAB21)

MGP:	100549805(RAB21)

CJO:	107310298(RAB21)

TPAI:

128073799(RAB21)

LMUT:

125691661(RAB21)

NMEL:

110392821(RAB21)

APLA:

101792835(RAB21)

ACYG:

106045372(RAB21)

CATA:

118246676(RAB21)

AFUL:

116502148(RAB21)

TGU:	100231417(RAB21)

LSR:	110469829(RAB21)

SCAN:

103813670(RAB21)

PMOA:

120499786(RAB21)

OTC:	121339431(RAB21)

PRUF:

121352488(RAB21)

ATRC:

139588276(RAB21)

GFR:	102036350(RAB21)

FAB:	101810923(RAB21)

OMA:	130262339(RAB21)

PHI:	102103595(RAB21)

PMAJ:

107204823(RAB21)

CCAE:

111937566(RAB21)

CBRC:

103614896(RAB21)

ACOE:

138101343(RAB21)

ETL:	114059990(RAB21)

ZAB:	102063758(RAB21)

ZLE:	135442295(RAB21)

ACHL:

103805076(RAB21)

SVG:	106855071(RAB21)

MMEA:

130580407(RAB21)

HRT:	120751599(RAB21)

SATI:

136361343(RAB21)

CCIC:

134043559(RAB21)

FPG:	101918532(RAB21)

FCH:	102052575(RAB21)

CCRI:

104168672(RAB21)

NNT:	104407583(RAB21)

SHAB:

115604666(RAB21)

ACUN:

113491121(RAB21)

TALA:

104362030(RAB21)

ACHC:

115336141(RAB21)

HLE:	104828328(RAB21)

AGEN:

126034407

HHAR:

128135403(RAB21)

GCL:

127029416

CSTI:

104551318(RAB21)

LDI:	104347361(RAB21)

MNB:	103772364(RAB21)

DPUB:

104300972(RAB21)

PPUS:

135187484(RAB21)

AVIT:

104268783(RAB21)

BRHI:

104500604(RAB21)

EGZ:	104132955(RAB21)

NNI:	104011040(RAB21)

PCRI:

104030610(RAB21)

PCAO:

104047998(RAB21)

PADL:

103920032(RAB21)

AFOR:

103893937(RAB21)

FGA:	104073623(RAB21)

GSTE:

104261845(RAB21)

CBOY:

140652627(RAB21)

CLV:	102092687(RAB21)

MUI:	104540621(RAB21)

PGUU:

104459547(RAB21)

PLET:

104616640(RAB21)

EHS:	104508106(RAB21)

CMAC:

104474411(RAB21)

CUCA:

104064028(RAB21)

TEO:	104375597(RAB21)

BREG:

104631062(RAB21)

OHA:	104326799(RAB21)

ACAR:

104531926(RAB21)

CPEA:

104388834(RAB21)

CVF:	104288945(RAB21)

RTD:	128904328(RAB21)

CRID:

134510083(RAB21)

AAM:	106488159(RAB21)

AROW:

112964113(RAB21)

NPD:	112958830(RAB21)

TGT:	104574971(RAB21)

DNE:	112983312(RAB21)

SCAM:

104140705(RAB21)

ASN:	102377570(RAB21)

AMJ:	102572583(RAB21)

CPOO:

109315487(RAB21)

GGN:	109295734(RAB21)

PSS:	102445891(RAB21)

CMY:	102933699(RAB21)

CCAY:

125630182(RAB21)

DCC:	119862338(RAB21)

CPIC:

101948155(RAB21)

TST:	117877897(RAB21)

CABI:

116839365(RAB21)

MRV:	120381708(RAB21)

ACS:	100551608(rab21)

ASAO:

132776154(RAB21)

PVT:	110085009(RAB21)

SUND:

121931299(RAB21)

PBI:	103063243(RAB21)

PMUR:

107283827(RAB21)

CTIG:

120308424(RAB21)

TSR:	106541685(RAB21)

PGUT:

117655484(RAB21)

APRI:

131202688(RAB21)

PTEX:

113435561(RAB21)

NSS:	113412249(RAB21)

VKO:	123033302(RAB21)

PMUA:

114604826(RAB21)

PRAF:

128422040(RAB21)

ZVI:	118091408(RAB21)

HCG:	128325967(RAB21)

GJA:	107115338(RAB21)

STOW:

125435655(RAB21)

EMC:	129336013(RAB21)

XLA:	108713146(rab21.S) 398907(rab21.L)

XTR:	549073(rab21)

NPR:	108788316(RAB21)

RTEM:

120931966(RAB21)

BBUF:

120980719(RAB21)

BGAR:

122928002(RAB21)

PWL:	138288202(RAB21)

MUO:	115477302(RAB21)

GSH:	117363912(RAB21)

DRE:	767727(rab21)

SRX:	107709968 107747645

SANH:

107687573 107690748

SGH:	107570114(rab21)

CCAR:

109064350 109094682(rab21)

CAUA:

113057178(rab21)

CGIB:

127956645

PTET:

122343121(rab21)

LROH:

127164042(rab21)

OMC:	131539560(rab21)

PPRM:

120462269(rab21)

RKG:	130092483(rab21)

MAMB:

125245736(rab21)

CIDE:

127511254

CERY:

137024648(rab21)

MASI:

127435351 127437026

TROS:

130549510(rab21)

TDW:	130421038(rab21)

MANU:

129431911(rab21)

PDAB:

135752548 135779263

IPU:

108280089

IFU:	128623095(rab21)

PHYP:

113532143(rab21)

SMEO:

124401630(rab21)

TFD:	113645589(rab21)

TVC:	132858810(rab21)

CGAR:

128534239(rab21)

NGRA:

132869555(rab21)

TRN:	134313229(rab21)

AMEX:

103040701(rab21)

CMAO:

118812226(rab21)

EEE:	113575809(rab21)

CHAR:

105892581(rab21)

SPIL:

134071349(rab21)

TRU:	101068045(rab21)

TFS:	130519530(rab21)

TNG:	GSTEN00003443G001

TBEN:

117487110(rab21)

PGEO:

117441915(rab21)

EMAC:

134879098(rab21)

ELY:	117249430(rab21)

EFO:	125882948(rab21)

SLUC:

116051988(rab21)

ECRA:

117938494(rab21)

PFLV:

114550150(rab21)

GAT:	120814098(rab21)

PPUG:

119210139(rab21)

AFB:	129112467(rab21)

CLUM:

117725955(rab21)

PSWI:

130200384(rab21)

CANA:

137791869(rab21)

CVE:	137889959(rab21)

MSAM:

119895008(rab21)

SCHU:

122870950(rab21)

CUD:	121505393(rab21)

SPUL:

138599757(rab21)

LMIX:

132956521(rab21)

ALAT:

119032533(rab21)

ASTR:

137589095(rab21)

MZE:	101475900(rab21)

ONL:	100709345(rab21)

OAU:	116319731(rab21)

OLA:	101158319(rab21)

OML:	112156905(rab21)

CSAI:

133424302(rab21)

XMA:	102230324(rab21)

XCO:	114161111(rab21)

XHE:	116736932(rab21)

PRET:

103459342(rab21)

PFOR:

103154271(rab21)

PLAI:

106957158(rab21)

PMEI:

106917299(rab21)

GAF:	122826523(rab21)

PPRL:

129352898(rab21)

CVG:	107089079(rab21)

CTUL:

119796589(rab21)

GMU:	124883215(rab21)

NFU:	107387637(rab21)

KMR:	108228812(rab21)

ALIM:

106532844(rab21)

NWH:	119428359(rab21)

AOCE:

111563455(rab21)

EJA:	138192192(rab21)

BFRE:

138633155(rab21)

MCEP:

124999871(rab21)

CSEM:

103383112(rab21)

POV:	109643614(rab21)

SSEN:

122761394(rab21)

SSOE:

131456618(rab21)

HHIP:

117757050(rab21)

HSP:	118101606(rab21)

PPLT:

128429113(rab21)

SMAU:

118287467(rab21)

LCF:

108901356

SDU:	111224765(rab21)

SLAL:

111664956(rab21)

XGL:	120802175(rab21)

HCQ:	109532605(rab21)

SSCV:

125991996(rab21)

SBIA:

133493267(rab21)

PEE:	133397404(rab21)

PTAO:

133471802(rab21)

BPEC:

110161638(rab21)

ENY:	140367422(rab21)

MALB:

109967748(rab21)

BSPL:

114862544(rab21)

SJO:	128385166(rab21)

SSCO:

134004273(rab21)

GMH:	115542476(rab21)

SASA:

106609839

STRU:

115189711 115189713

OTW:	112241931(rab21)

OMY:	110490591 110500958

OGO:

123995981

OKI:	116360636 116361747

OKE:	127927270(rab21)

OMM:	135532550(rab21)

OCLA:

139393243 139394654

SALP:

112076400(rab21)

SNH:	120036840 120042200

CCLU:

121553382 123480995

ELS:	105023118(rab21)

OEP:	134037759(rab21)

SFM:	108936608(rab21) 108942190

PKI:	111851520(rab21) 111858646

AANG:

118219172 118232509

AROT:

135245595 135258799(rab21)

CCOG:

133119020 133134425

LOC:	102699089(rab21)

PSPA:

121318035(rab21) 121319147

ARUT:

117415909 117420008

PSEX:

120534375(rab21)

LCM:	102364231(RAB21)

CMK:	103182442 103185328(rab21)

RTP:	109915422(rab21)

CPLA:

122563073

HOC:	132824899 132828144

LERI:

129706435 129708862

PMRN:

116939857(RAB21)

LRJ:

BFO:

BBEL:

CIN:

SCLV:

SPU:	105439762 105439764

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG17515(Rab21)

DER:

6549980

DSE:

6620096

DSI:	Dsimw501_GD22429(Dsim_GD22429)

DYA:	Dyak_GE15254

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DMO:	Dmoj_GI14949

DAZ:

108618826

DNV:

108656147

DHE:

111598401

DVI:	6631859(Rab21)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:	119669234 119670890

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135958599(Rab21)

GFS:

ECOE:

HIS:

CBRI:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139101780(Rab21)

HST:

DQU:

CFO:

FEX:

PMEC:

138939376(Rab21)

LHU:	105672237(Rab21)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124213110(Rab21)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138126899(Rab21)

DPA:

109542296

ESIM:

136416788(Rab21)

EFOR:

136339942(Rab21)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

DCOR:

135793367(Rab21)

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_200914

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106689643(Rab21)

NLU:

111050066

HVI:

124374836

MQU:	128994373 129004869

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138703004(Rab21)

SGRE:

126365839

BROR:

134538855

IEL:

124159308

HAMR:

139691788(Rab21)

DPX:	DAPPUDRAFT_305964

DMK:

DPZ:

AFRA:

PJA:

PCHN:

HAME:

PCLA:

123760357(Rab21)

CQD:	128686377(Rab21)

PTRU:

123516608

ESN:

126988742

MNZ:

135203168

MRJ:	136835011(Rab21)

PORN:

139766223(Rab21)

HAZT:

EAF:

TCF:

ISC:

DSV:

RSAN:

RMP:

CSCU:

CVS:	136984303(Rab21)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_T01B7.3(rab-21)

CBR:	CBG_03162(Cbr-rab-21)

CRQ:	GCK72_005590

BMY:	BM_BM5453(Bma-rab-21)

LOA:	LOAG_08070

LGI:	LOTGIDRAFT_235789

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:	115232407 115232509

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_61818

NNU:

MING:

TSS:

PSOM:

OSA:

DOSA:

OBR:

OGL:

MFLO:

SITA:

SVS:

PAUA:

PDA:

EGU:

MUS:

ZOF:	122001150 122005435

MSIN:

ACAK:

ATR:

CJF:

SMO:	SELMODRAFT_230104(Rab21-1)

PPP:

112288244

OLU:	OSTLU_32150

OTA:	OT_ostta06g02160

AAF:	AURANDRAFT_22182

PIF:	PITG_11726 PITG_19907

PSOJ:

PHYSODRAFT_350023

BLAC:

94349037(CCR75_005284)

SPAR:

SPRG_11446

NGR:	NAEGRDRAFT_82940

» show all

Reference

PMID:22648168

Authors

Jean S, Cox S, Schmidt EJ, Robinson FL, Kiger A

Title

Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling.

Journal

Mol Biol Cell 23:2723-40 (2012)
DOI:10.1091/mbc.E12-05-0375

Sequence

[dme:Dmel_CG17515]

Reference

PMID:18804435

Authors

Pellinen T, Tuomi S, Arjonen A, Wolf M, Edgren H, Meyer H, Grosse R, Kitzing T, Rantala JK, Kallioniemi O, Fassler R, Kallio M, Ivaska J

Title

Integrin trafficking regulated by Rab21 is necessary for cytokinesis.

Journal

Dev Cell 15:371-85 (2008)
DOI:10.1016/j.devcel.2008.08.001

Sequence

[hsa:23011] [mmu:216344]

LinkDB

DBGET integrated database retrieval system