Loxodonta africana (African savanna elephant): 100653632 Help Entry 100653632         CDS       T04351                                  Symbol TPM2 Name (RefSeq) tropomyosin beta chain isoform X3   KO K10374   tropomyosin 2 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04814   Motor proteins lav04820   Cytoskeleton in muscle cells lav05410   Hypertrophic cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     100653632 (TPM2)    04820 Cytoskeleton in muscle cells     100653632 (TPM2)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     100653632 (TPM2)    04261 Adrenergic signaling in cardiomyocytes     100653632 (TPM2)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100653632 (TPM2)    05414 Dilated cardiomyopathy     100653632 (TPM2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:lav04812]     100653632 (TPM2) Cytoskeleton proteins [BR:lav04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Tropomyosins      100653632 (TPM2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tropomyosin CLZ Laminin_II PUMA_CC ERM_helical TMF_DNA_bd DUF3450 Snapin_Pallidin Cluap1 DASH_Duo1 CENP-F_leu_zip ADIP ATG16 Crescentin Suppressor_APC DUF7310 Laminin_I XhlA Motif Other DBs NCBI-GeneID:  100653632 NCBI-ProteinID:  XP_003407342 LinkDB All DBs Position Unknown AA seq 284 aa AA seqDB search MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY SESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEQAEKAA DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL NT seq 855 nt NT seq  +upstreamnt  +downstreamnt atggacgccatcaagaagaagatgcagatgctaaagctggacaaggagaatgctatcgat cgcgccgagcaggccgaggccgacaagaaacaagctgaggaccgctgcaagcagctggag gaggagcagcaagccctccagaagaagctgaaggggacggaggacgaggtggaaaagtat tctgagtcagtgaaggatgcccaggagaaactggagcaggctgagaagaaagccacagac gccgaggcagatgtggcctccctgaaccgccgcattcagctagtagaggaggagctggac cgggcacaggagcgtctggccactgccctgcaaaagctggagcaggctgagaaggcagcc gatgagagtgagagaggaatgaaggtcattgaaaaccgggccatgaaggatgaggaaaag atggagcttcaggagatgcagctgaaggaggccaagcacattgctgaggactcagaccgc aaatacgaggaggtggccaggaagctggtgatcctggaaggagagctagaacgctcagaa gagagggctgaggtggctgagagtaaatgtggggacctagaggaagaactgaaaattgtt accaacaacttgaaatccctggaggcccaagcagacaagtattccaccaaagaggataaa tatgaagaggagatcaaactgctggaggagaaactgaaggaggctgagacccgagcagaa tttgccgaaagatctgtggcaaaactggagaaaaccatcgatgacctagaagagaccttg gccagtgccaaggaggagaatgtggagattcaccagaccctggaccagaccctgctggaa ctcaacaacctctga

Loxodonta africana (African savanna elephant): 100666675 Help Entry 100666675         CDS       T04351                                  Symbol TPM1 Name (RefSeq) tropomyosin alpha-1 chain isoform X5   KO K10373   tropomyosin 1 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04814   Motor proteins lav04820   Cytoskeleton in muscle cells lav05206   MicroRNAs in cancer lav05410   Hypertrophic cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     100666675 (TPM1)    04820 Cytoskeleton in muscle cells     100666675 (TPM1)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     100666675 (TPM1)    04261 Adrenergic signaling in cardiomyocytes     100666675 (TPM1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100666675 (TPM1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100666675 (TPM1)    05414 Dilated cardiomyopathy     100666675 (TPM1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:lav04812]     100666675 (TPM1)    04147 Exosome [BR:lav04147]     100666675 (TPM1) Cytoskeleton proteins [BR:lav04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Tropomyosins      100666675 (TPM1) Exosome [BR:lav04147]  Exosomal proteins   Exosomal proteins of microglial cells    100666675 (TPM1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tropomyosin CLZ Laminin_II TMF_DNA_bd ERM_helical PUMA_CC TMP_N ATG16 Crescentin DUF745 Laminin_I CENP-F_leu_zip Fib_alpha ADIP CCDC22_CC Motif Other DBs NCBI-GeneID:  100666675 NCBI-ProteinID:  XP_003418384 LinkDB All DBs Position Unknown AA seq 284 aa AA seqDB search MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDKYEEEIKVLSDKLKEAETRAE FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM NT seq 855 nt NT seq  +upstreamnt  +downstreamnt atggacgccatcaagaagaagatgcagatgctgaagctcgacaaggagaacgccttggat cgagccgagcaggcggaggcggataagaaggccgctgaagaccggagcaagcagctggaa gacgagctggtatcgctgcaaaagaaactcaagggcactgaagatgaactggacaaatac tccgaggctctcaaagatgcccaggagaagctggagctggctgagaaaaaggccacggat gctgaagccgatgtagcgtctctgaacagacgcatccagctggttgaggaagagttggat cgtgcccaggagcgtctggccacagctttgcagaagctggaggaggccgagaaggcagca gacgagagtgagagaggcatgaaagtcattgagagtcgagcccaaaaggatgaggaaaaa atggaaattcaggagatccaactcaaagaggccaagcacattgctgaagatgcagaccgc aagtacgaggaggtggcccgtaagctggtcatcattgagagtgaccttgaacgtgcagag gagagggctgagctctcagaaggccaagttcgacagctggaagaacaattaagaataatg gatcagaccttgaaagcattaatggctgcagaggataagtactcgcagaaggaggacaag tatgaggaagagatcaaggtcctttctgacaagctgaaggaggctgagacacgggccgag tttgcagagaggtcagtaactaaattggagaaaagcattgatgacttagaagagaaagtg gctcatgccaaagaagaaaaccttagtatgcatcagatgctggatcagactttactggag ttaaacaacatgtga

Loxodonta africana (African savanna elephant): 100671189 Help Entry 100671189         CDS       T04351                                  Symbol TPM4 Name (RefSeq) tropomyosin alpha-4 chain   KO K10375   tropomyosin 4 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04814   Motor proteins lav04820   Cytoskeleton in muscle cells lav05410   Hypertrophic cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     100671189 (TPM4)    04820 Cytoskeleton in muscle cells     100671189 (TPM4)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     100671189 (TPM4)    04261 Adrenergic signaling in cardiomyocytes     100671189 (TPM4)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100671189 (TPM4)    05414 Dilated cardiomyopathy     100671189 (TPM4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:lav04812]     100671189 (TPM4) Cytoskeleton proteins [BR:lav04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Tropomyosins      100671189 (TPM4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tropomyosin CLZ Laminin_II ERM_helical ATG16 DUF3450 FPP Laminin_I DUF1664 CENP-F_leu_zip NBP1 MscS_porin PUMA_CC Crescentin XhlA DUF4200 GAS ADIP DUF745 Nuf2_DHR10-like Motif Other DBs NCBI-GeneID:  100671189 NCBI-ProteinID:  XP_003413090 LinkDB All DBs Position Unknown AA seq 284 aa AA seqDB search MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDMY SENLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLAAALQKLEEAEKAA DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVVLEGELERAE ERAEVAELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLVSDKLKEAETRAE FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI NT seq 855 nt NT seq  +upstreamnt  +downstreamnt atggaggccatcaagaagaagatgcagatgctgaagctggacaaggagaacgccatcgac cgcgctgagcaggcggaggccgacaagaaggccgccgaggacaagtgtaagcaggtggag gaggagctaacacacctccagaaaaagctgaaggggacggaagacgagctggacatgtac tcggagaacctgaaggacgcgcaggagaagctggagctgactgagaagaaagcctccgat gctgaaggtgatgtggcagctctcaaccgacgcatccagcttgtggaggaggagctggac agggctcaggagcgcctggctgcggccctgcagaaactggaggaggcggagaaggctgca gatgaaagtgagagaggcatgaaggtgatagagaaccgggccatgaaagacgaggagaag atggaaatccaggagatgcagctcaaagaggccaagcacattgctgaggaggccgaccgc aaatacgaggaggtagctcgtaagctggtcgtcctggagggcgagctggagcgagcagag gaacgtgcagaggtggctgaactaaaatgtggtgacctggaagaagaactcaagaatgtc acaaacaatctgaaatcgctggaggcggcctcagaaaagtattctgaaaaggaggataaa tatgaagaagaaattaaacttgtgtctgacaaactgaaagaggctgagacccgtgctgag tttgcagagagaacggttgcaaaactggaaaagaccattgatgacctggaagaaaaactt gcccaggccaaagaagagaacgtgggcttacatcagacactggatcagacactaaacgaa cttaactgtatataa

Loxodonta africana (African savanna elephant): 100674827 Help Entry 100674827         CDS       T04351                                  Symbol TPM3 Name (RefSeq) tropomyosin alpha-3 chain isoform X1   KO K09290   tropomyosin 3 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav04814   Motor proteins lav04820   Cytoskeleton in muscle cells lav05200   Pathways in cancer lav05216   Thyroid cancer lav05410   Hypertrophic cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     100674827 (TPM3)    04820 Cytoskeleton in muscle cells     100674827 (TPM3)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     100674827 (TPM3)    04261 Adrenergic signaling in cardiomyocytes     100674827 (TPM3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100674827 (TPM3)   09162 Cancer: specific types    05216 Thyroid cancer     100674827 (TPM3)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100674827 (TPM3)    05414 Dilated cardiomyopathy     100674827 (TPM3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:lav04812]     100674827 (TPM3) Cytoskeleton proteins [BR:lav04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Tropomyosins      100674827 (TPM3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tropomyosin Laminin_II TMF_DNA_bd TMP_N CLZ HR1 PUMA_CC DUF745 CENP-F_leu_zip WS_DGAT_cat BORCS7 CALCOCO1 MAD LptF_LptG Motif Other DBs NCBI-GeneID:  100674827 NCBI-ProteinID:  XP_003415144 UniProt:  G3TYJ3 LinkDB All DBs Position Unknown AA seq 248 aa AA seqDB search MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ KEDKYEEEIKILSDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ TLLDLNEM NT seq 747 nt NT seq  +upstreamnt  +downstreamnt atggccgggatcaccaccatcgaggcggtgaagcgcaagatccaggttctgcagcagcag gccgatgatgccgaggagagggccgagcgcctccagcgggaagtggagggggaaaggcgg gcccgggaacaggctgaggctgaggtggcctccttgaaccgtcggatccagctggttgaa gaggagctggaccgtgctcaggagcgtctggccactgccctgcaaaagctggaggaggca gagaaagctgctgatgagagcgagagaggtatgaaggttattgaaaaccgggccttaaaa gatgaagagaagatggaactccaggaaatccaactcaaagaagctaaacacattgcagaa gaggcagatcggaagtacgaggaggtggctcgtaagttggtgattattgaaggggacttg gaacgcacagaggagcgagctgagctggcagagtcccgttgccgagagatggatgagcag atcagactgatggaccagaacctgaagtgtctgagtgctgctgaagaaaagtactctcaa aaagaagacaaatatgaggaagagataaagatactttctgataaactcaaggaggcagag acccgtgctgagtttgctgagagatcggtagccaagctggaaaagacaattgatgatttg gaagataaactgaaatgcaccaaagaggagcacctctgtacacaaaggatgctggaccag actctgcttgacctgaatgagatgtag

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