Loxodonta africana (African savanna elephant): 100653632 Help Entry 100653632         CDS       T04351                                  Gene name TPM2 Definition (RefSeq) tropomyosin beta chain isoform X3   KO K10374   tropomyosin 2 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav05410   Hypertrophic cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     100653632 (TPM2)    04261 Adrenergic signaling in cardiomyocytes     100653632 (TPM2)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100653632 (TPM2)    05414 Dilated cardiomyopathy     100653632 (TPM2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:lav04812]     100653632 (TPM2) Cytoskeleton proteins [BR:lav04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Tropomyosins      100653632 (TPM2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tropomyosin Tropomyosin_1 CLZ Laminin_II ERM TMF_DNA_bd Crescentin DUF3450 SNARE Cluap1 Snapin_Pallidin DASH_Duo1 ADIP ATG16 CENP-F_leu_zip HrpB7 Suppressor_APC DUF1664 Laminin_I Motif Other DBs NCBI-GeneID:  100653632 NCBI-ProteinID:  XP_003407342 LinkDB All DBs Position Unknown AA seq 284 aa AA seqDB search MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY SESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEQAEKAA DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL NT seq 855 nt NT seq  +upstreamnt  +downstreamnt atggacgccatcaagaagaagatgcagatgctaaagctggacaaggagaatgctatcgat cgcgccgagcaggccgaggccgacaagaaacaagctgaggaccgctgcaagcagctggag gaggagcagcaagccctccagaagaagctgaaggggacggaggacgaggtggaaaagtat tctgagtcagtgaaggatgcccaggagaaactggagcaggctgagaagaaagccacagac gccgaggcagatgtggcctccctgaaccgccgcattcagctagtagaggaggagctggac cgggcacaggagcgtctggccactgccctgcaaaagctggagcaggctgagaaggcagcc gatgagagtgagagaggaatgaaggtcattgaaaaccgggccatgaaggatgaggaaaag atggagcttcaggagatgcagctgaaggaggccaagcacattgctgaggactcagaccgc aaatacgaggaggtggccaggaagctggtgatcctggaaggagagctagaacgctcagaa gagagggctgaggtggctgagagtaaatgtggggacctagaggaagaactgaaaattgtt accaacaacttgaaatccctggaggcccaagcagacaagtattccaccaaagaggataaa tatgaagaggagatcaaactgctggaggagaaactgaaggaggctgagacccgagcagaa tttgccgaaagatctgtggcaaaactggagaaaaccatcgatgacctagaagagaccttg gccagtgccaaggaggagaatgtggagattcaccagaccctggaccagaccctgctggaa ctcaacaacctctga

Loxodonta africana (African savanna elephant): 100666675 Help Entry 100666675         CDS       T04351                                  Gene name TPM1 Definition (RefSeq) tropomyosin alpha-1 chain isoform X5   KO K10373   tropomyosin 1 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav05206   MicroRNAs in cancer lav05410   Hypertrophic cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     100666675 (TPM1)    04261 Adrenergic signaling in cardiomyocytes     100666675 (TPM1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100666675 (TPM1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100666675 (TPM1)    05414 Dilated cardiomyopathy     100666675 (TPM1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:lav04812]     100666675 (TPM1)    04147 Exosome [BR:lav04147]     100666675 (TPM1) Cytoskeleton proteins [BR:lav04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Tropomyosins      100666675 (TPM1) Exosome [BR:lav04147]  Exosomal proteins   Exosomal proteins of microglial cells    100666675 (TPM1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tropomyosin Tropomyosin_1 CLZ Laminin_II TMF_DNA_bd ERM COG2 ADIP Laminin_I DUF745 Fib_alpha ATG16 AAA_13 HrpB7 DUF1664 CENP-F_leu_zip Motif Other DBs NCBI-GeneID:  100666675 NCBI-ProteinID:  XP_003418384 LinkDB All DBs Position Unknown AA seq 284 aa AA seqDB search MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDKYEEEIKVLSDKLKEAETRAE FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM NT seq 855 nt NT seq  +upstreamnt  +downstreamnt atggacgccatcaagaagaagatgcagatgctgaagctcgacaaggagaacgccttggat cgagccgagcaggcggaggcggataagaaggccgctgaagaccggagcaagcagctggaa gacgagctggtatcgctgcaaaagaaactcaagggcactgaagatgaactggacaaatac tccgaggctctcaaagatgcccaggagaagctggagctggctgagaaaaaggccacggat gctgaagccgatgtagcgtctctgaacagacgcatccagctggttgaggaagagttggat cgtgcccaggagcgtctggccacagctttgcagaagctggaggaggccgagaaggcagca gacgagagtgagagaggcatgaaagtcattgagagtcgagcccaaaaggatgaggaaaaa atggaaattcaggagatccaactcaaagaggccaagcacattgctgaagatgcagaccgc aagtacgaggaggtggcccgtaagctggtcatcattgagagtgaccttgaacgtgcagag gagagggctgagctctcagaaggccaagttcgacagctggaagaacaattaagaataatg gatcagaccttgaaagcattaatggctgcagaggataagtactcgcagaaggaggacaag tatgaggaagagatcaaggtcctttctgacaagctgaaggaggctgagacacgggccgag tttgcagagaggtcagtaactaaattggagaaaagcattgatgacttagaagagaaagtg gctcatgccaaagaagaaaaccttagtatgcatcagatgctggatcagactttactggag ttaaacaacatgtga

Loxodonta africana (African savanna elephant): 100671189 Help Entry 100671189         CDS       T04351                                  Gene name TPM4 Definition (RefSeq) tropomyosin alpha-4 chain   KO K10375   tropomyosin 4 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav05410   Hypertrophic cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     100671189 (TPM4)    04261 Adrenergic signaling in cardiomyocytes     100671189 (TPM4)  09160 Human Diseases   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100671189 (TPM4)    05414 Dilated cardiomyopathy     100671189 (TPM4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:lav04812]     100671189 (TPM4) Cytoskeleton proteins [BR:lav04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Tropomyosins      100671189 (TPM4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tropomyosin Tropomyosin_1 CLZ Laminin_II ATG16 DUF3450 ERM Laminin_I Crescentin DUF1664 FPP CENP-F_leu_zip NBP1 HrpB7 CCDC144C XhlA DHR10 GAS ADIP FliJ TPR_MLP1_2 Spc7 Motif Other DBs NCBI-GeneID:  100671189 NCBI-ProteinID:  XP_003413090 LinkDB All DBs Position Unknown AA seq 284 aa AA seqDB search MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDMY SENLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLAAALQKLEEAEKAA DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVVLEGELERAE ERAEVAELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLVSDKLKEAETRAE FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI NT seq 855 nt NT seq  +upstreamnt  +downstreamnt atggaggccatcaagaagaagatgcagatgctgaagctggacaaggagaacgccatcgac cgcgctgagcaggcggaggccgacaagaaggccgccgaggacaagtgtaagcaggtggag gaggagctaacacacctccagaaaaagctgaaggggacggaagacgagctggacatgtac tcggagaacctgaaggacgcgcaggagaagctggagctgactgagaagaaagcctccgat gctgaaggtgatgtggcagctctcaaccgacgcatccagcttgtggaggaggagctggac agggctcaggagcgcctggctgcggccctgcagaaactggaggaggcggagaaggctgca gatgaaagtgagagaggcatgaaggtgatagagaaccgggccatgaaagacgaggagaag atggaaatccaggagatgcagctcaaagaggccaagcacattgctgaggaggccgaccgc aaatacgaggaggtagctcgtaagctggtcgtcctggagggcgagctggagcgagcagag gaacgtgcagaggtggctgaactaaaatgtggtgacctggaagaagaactcaagaatgtc acaaacaatctgaaatcgctggaggcggcctcagaaaagtattctgaaaaggaggataaa tatgaagaagaaattaaacttgtgtctgacaaactgaaagaggctgagacccgtgctgag tttgcagagagaacggttgcaaaactggaaaagaccattgatgacctggaagaaaaactt gcccaggccaaagaagagaacgtgggcttacatcagacactggatcagacactaaacgaa cttaactgtatataa

Loxodonta africana (African savanna elephant): 100674827 Help Entry 100674827         CDS       T04351                                  Gene name TPM3 Definition (RefSeq) tropomyosin alpha-3 chain isoform X1   KO K09290   tropomyosin 3 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav04260   Cardiac muscle contraction lav04261   Adrenergic signaling in cardiomyocytes lav05200   Pathways in cancer lav05216   Thyroid cancer lav05410   Hypertrophic cardiomyopathy lav05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lav00001]  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     100674827 (TPM3)    04261 Adrenergic signaling in cardiomyocytes     100674827 (TPM3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100674827 (TPM3)   09162 Cancer: specific types    05216 Thyroid cancer     100674827 (TPM3)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100674827 (TPM3)    05414 Dilated cardiomyopathy     100674827 (TPM3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:lav04812]     100674827 (TPM3) Cytoskeleton proteins [BR:lav04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Tropomyosins      100674827 (TPM3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tropomyosin Tropomyosin_1 Laminin_II TMF_DNA_bd CLZ CENP-F_leu_zip WES_acyltransf DUF745 DUF1664 EzrA BORCS7 Lebercilin MAD Fib_alpha Crescentin Motif Other DBs NCBI-GeneID:  100674827 NCBI-ProteinID:  XP_003415144 UniProt:  G3TYJ3 LinkDB All DBs Position Unknown AA seq 248 aa AA seqDB search MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ KEDKYEEEIKILSDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ TLLDLNEM NT seq 747 nt NT seq  +upstreamnt  +downstreamnt atggccgggatcaccaccatcgaggcggtgaagcgcaagatccaggttctgcagcagcag gccgatgatgccgaggagagggccgagcgcctccagcgggaagtggagggggaaaggcgg gcccgggaacaggctgaggctgaggtggcctccttgaaccgtcggatccagctggttgaa gaggagctggaccgtgctcaggagcgtctggccactgccctgcaaaagctggaggaggca gagaaagctgctgatgagagcgagagaggtatgaaggttattgaaaaccgggccttaaaa gatgaagagaagatggaactccaggaaatccaactcaaagaagctaaacacattgcagaa gaggcagatcggaagtacgaggaggtggctcgtaagttggtgattattgaaggggacttg gaacgcacagaggagcgagctgagctggcagagtcccgttgccgagagatggatgagcag atcagactgatggaccagaacctgaagtgtctgagtgctgctgaagaaaagtactctcaa aaagaagacaaatatgaggaagagataaagatactttctgataaactcaaggaggcagag acccgtgctgagtttgctgagagatcggtagccaagctggaaaagacaattgatgatttg gaagataaactgaaatgcaccaaagaggagcacctctgtacacaaaggatgctggaccag actctgcttgacctgaatgagatgtag

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