KEGG ORTHOLOGY: K09290

ORTHOLOGY: K09290

Entry

K09290                      KO

Symbol

TPM3

Name

tropomyosin 3

Pathway

map04260

Cardiac muscle contraction

map04261

Adrenergic signaling in cardiomyocytes

map04814

Motor proteins

map04820

Cytoskeleton in muscle cells

map05200

Pathways in cancer

map05216

Thyroid cancer

map05410

Hypertrophic cardiomyopathy

map05414

Dilated cardiomyopathy

Disease

H00032

Thyroid cancer

H00698

Nemaline myopathy

H00701

Congenital fiber type disproportion

H00702

Cap myopathy

H01810

Congenital myopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    K09290  TPM3; tropomyosin 3
   04820 Cytoskeleton in muscle cells
    K09290  TPM3; tropomyosin 3
09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K09290  TPM3; tropomyosin 3
   04261 Adrenergic signaling in cardiomyocytes
    K09290  TPM3; tropomyosin 3
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K09290  TPM3; tropomyosin 3
  09162 Cancer: specific types
   05216 Thyroid cancer
    K09290  TPM3; tropomyosin 3
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K09290  TPM3; tropomyosin 3
   05414 Dilated cardiomyopathy
    K09290  TPM3; tropomyosin 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K09290  TPM3; tropomyosin 3
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Tropomyosins
     K09290  TPM3; tropomyosin 3

Other DBs

GO:

0005862

Genes

HSA:	7170(TPM3)

PTR:	458000(TPM3) 470670

PPS:	100977130(TPM3) 100979041 103786661

GGO:	101150029(TPM3) 109025964

PON:	100174017(TPM3)

NLE:	100598772 100600342(TPM3)

HMH:	116469370(TPM3)

MCC:	716336(TPM3)

MCF:	101925252(TPM3) 102143897

MTHB:

126934335

MNI:	105497962(TPM3)

CSAB:

103223933(TPM3)

CATY:

105581062 105593482(TPM3)

PANU:

101022375(TPM3)

TGE:	112634916 112636488(TPM3)

MLEU:

105540689 105554059(TPM3)

RRO:	104663504(TPM3) 104677298 115898675

RBB:	108517077 108517668(TPM3)

TFN:	117089706 117090245 117093642

PTEH:

111530405 111543713(TPM3) 113219991

CANG:

105501997(TPM3) 105509672 105514649 105523059

CJC:	100386874 100393965 100412800(TPM3)

SBQ:	101038731(TPM3) 101040194 101052248 101052619

CIMI:

108292440(TPM3) 108307695

CSYR:

103250795 103260087 103262877(TPM3) 103267800

MMUR:

105855383 105885920(TPM3)

LCAT:

123634014(TPM3)

PCOQ:

105821796(TPM3)

OGA:	100941107 100966951(TPM3)

MMU:	59069(Tpm3)

MCAL:

110290600(Tpm3)

MPAH:

110320701(Tpm3)

RNO:	117557(Tpm3)

MCOC:

116093202(Tpm3) 116093484

ANU:	117706699(Tpm3)

MUN:

110554253

CGE:	100763482(Tpm3) 103164511 113833120

MAUA:

101822952(Tpm3)

PROB:

127233030(Tpm3)

PLEU:

114707877(Tpm3)

MORG:

121450391(Tpm3)

MFOT:

126516128

AAMP:

119800649(Tpm3)

NGI:	103751563(Tpm3)

HGL:	101701017(Tpm3) 101713035

CPOC:

100728267(Tpm3)

CCAN:

109688045(Tpm3)

DORD:

105981274 106002414

DSP:	122108101 122109756(Tpm3)

PLOP:

125360089(Tpm3)

NCAR:

124974851 124983652 124993462

MMMA:

107141701 107141896 107156756(Tpm3)

OCU:	100349893 100351420

OPI:	101524569(TPM3)

TUP:	102489298(TPM3)

GVR:	103607884(TPM3)

CFA:	480137(TPM3) 489252 491979

CLUD:

112647737(TPM3) 112666045

VVP:	112913093 112918879(TPM3)

VLG:	121476874 121484774(TPM3)

NPO:	129508744(TPM3) 129509253

AML:	100482767(TPM3) 117799607

UMR:	103668407(TPM3) 103668718

UAH:	113245168 113245319

UAR:	123783251(TPM3)

ELK:

111138967

LLV:	125085655 125103632 125104436

MPUF:

101681825(TPM3)

MNP:	132025942(TPM3)

MLK:	131814624(TPM3)

NVS:	122918227(TPM3)

ORO:	101378465(TPM3)

EJU:	114198692(TPM3) 114198695

ZCA:	113925838 113931949(TPM3)

MLX:	118004404 118013841(TPM3)

NSU:	110573579(TPM3) 110576922

LWW:	102741716(TPM3)

FCA:	101099019(TPM3)

PYU:	121015674(TPM3)

PCOO:

112851757(TPM3)

PBG:	122475969(TPM3)

PVIV:

125155798(TPM3)

LRUF:

124521247 124521888

PTG:	102950759 102952176(TPM3)

PPAD:

109256216(TPM3)

PUC:	125922516 125925744

AJU:

106987255

HHV:	120221531(TPM3)

BTA:	101904481 101906472 104970173 497019(TPM3)

BOM:	102268598 102278432 102283564(TPM3)

BIU:	109554330(TPM3)

BBUB:

102394237 102400496 102401750(TPM3) 112583857

BBIS:

104987441(TPM3) 104994615 104994681 105002326

CHX:	102179435(TPM3)

OAS:	101108973(TPM3) 101118433 114114091

BTAX:

128044429(TPM3) 128048068 128050312

ODA:	120855773(TPM3) 120857762

CCAD:

122433151(TPM3) 122435468 122441529

MBEZ:

129541774(TPM3) 129548206 129562093

SSC:	414388(TPM3)

CFR:	102518235(TPM3)

CBAI:

105068190(TPM3)

CDK:	105089246(TPM3)

VPC:	102531911(TPM3)

BACU:

103000535(TPM3) 103002139 103004609

BMUS:

118889574 118896657 118898138(TPM3)

LVE:	103082412(TPM3)

OOR:	101283198(TPM3)

DLE:	111167157(TPM3) 111174776

PCAD:

102987698(TPM3)

PSIU:

116739990(TPM3) 116753490

NASI:

112401747(TPM3)

ECB:	100056751(TPM3)

EPZ:	103555405(TPM3)

EAI:	106846242(TPM3)

MYB:	102259211(TPM3)

MYD:	102751364 102773123(TPM3)

MMYO:

118657297 118664998 118672903(TPM3)

MLF:	102439438(TPM3)

PKL:	118721123(TPM3)

EFUS:

103298926(TPM3)

MNA:	107543812(TPM3)

DRO:	112316450(TPM3)

SHON:

118990194(TPM3)

AJM:	119061771(TPM3)

PDIC:

114488738(TPM3)

PHAS:

123833461(TPM3)

MMF:	118637026(TPM3)

PPAM:

129062248(TPM3) 129069818

HAI:	109373515(TPM3)

RFQ:	117014457(TPM3)

PALE:

102898874(TPM3)

PGIG:

120592165(TPM3) 120604554(TPM1)

PVP:	105296457(TPM3)

RAY:	107509189(TPM3)

MJV:	108394124(TPM3)

TOD:	119237060(TPM3)

SARA:

101549588(TPM3)

SETR:

126015995 126020750(TPM3) 126022839

LAV:	100674827(TPM3)

TMU:

101341529

ETF:	101654867(TPM3)

DNM:	101410672 101446217(TPM3)

MDO:	100015402(TPM3)

GAS:	123245679(TPM3)

SHR:	100916994(TPM3)

AFZ:

127559867

PCW:	110211987(TPM3)

OAA:	100074158 100081283

GGA:	396430(TPM2) 770103(TPM3)

PCOC:

116237314(TPM3)

MGP:	100539084(TPM3)

CJO:	107324478(TPM3)

TPAI:

128073459(TPM3)

LMUT:

125685926 125685927

NMEL:

110387959(TPM3) 110387964

APLA:

101794835(TPM3)

ACYG:

106048522

CATA:

118258462(TPM3)

AFUL:

116499611(TPM3)

TGU:	100228823(TPM3)

LSR:	110471520(TPM3)

SCAN:

103823969(TPM3)

PMOA:

120498880(TPM3)

OTC:	121332098(TPM3)

PRUF:

121352136(TPM3)

GFR:	102032139(TPM3)

FAB:	101817683(TPM3)

OMA:	130263202(TPM3) 130264763(TPM2)

PHI:	102102780(TPM3)

PMAJ:

107214575(TPM3)

CCAE:

111939456(TPM3)

CBRC:

103611245(TPM3)

ETL:	114068434(TPM3)

ZAB:	102062141(TPM3)

ACHL:

103806137(TPM3)

SVG:	106863377(TPM3)

MMEA:

130583204(TPM3)

HRT:

120764269

FPG:	101918283(TPM3)

FCH:	102057451(TPM3)

CLV:	102093511(TPM3)

EGZ:	104123071(TPM3)

NNI:	104011981(TPM3)

PCRI:

PLET:

EHS:

PCAO:

ACUN:

TALA:

104356577(TPM3)

PADL:

103913884(TPM3)

AFOR:

103902348(TPM3)

ACHC:

115338507 115346352(TPM3)

HALD:

104312192

HLE:	104829660(TPM3)

AGEN:

126035316 126035905 126040396

GCL:

127027043

CCRI:

104166080(TPM3)

CSTI:

104550806

CMAC:

104485871 104486035

BREG:

104642274(TPM3)

FGA:

104071770

GSTE:

104261487(TPM3)

LDI:	104346131 104353173

MNB:

103769803

OHA:

104332893

NNT:

104402150

SHAB:

115602715(TPM3) 115609501 115619814(TPM2)

PGUU:

104460091 104470154

ACAR:

104528750

CPEA:

104390606(TPM3)

AVIT:

104279908(TPM3)

CVF:	104292236(TPM3)

RTD:	128900926(TPM3)

CUCA:

104058755

TEO:

104378344

BRHI:

104489590 104500985

AAM:	106484291(TPM3)

AROW:

112973220(TPM3)

NPD:	112950612(TPM3) 112952184(TPM2)

TGT:	104574608(TPM3)

DNE:	112991934 112994383(TPM3)

SCAM:

104141350(TPM3)

ASN:	102378388(TPM3)

AMJ:	102557705(TPM3)

CPOO:

109324775(TPM3)

GGN:	109304925(TPM3)

PSS:	102457475(TPM3)

CMY:	102940108(TPM3)

CCAY:

125625632(TPM3)

DCC:	119847595(TPM3)

CPIC:

101941050(TPM3)

TST:	117888446(TPM3)

CABI:

116832729(TPM3)

MRV:	120390011(TPM3)

ACS:	100555890(tpm3)

ASAO:

132764102(TPM3)

PVT:	110088481(TPM3)

SUND:

121916285(TPM3) 121918799 121918818

PBI:	103056624(TPM3)

PMUR:

107285200(TPM3)

CTIG:

120317190(TPM3) 120319775(TPM2)

PGUT:

117657973(TPM3)

APRI:

131186343(TPM3)

PTEX:

113451946

NSS:

113429591

VKO:

123032519

PMUA:

114586747(TPM3)

PRAF:

128403701(TPM3)

ZVI:	118075641(TPM3) 118092467

HCG:	128337033(TPM3)

GJA:	107117066 107117103

STOW:

125440521(TPM3)

EMC:	129340193(TPM3)

XLA:	397944 398952(tpm3.S) 399420(tpm3.L)

XTR:	116406865 394917(MGC76092)

NPR:	108798807(TPM3)

RTEM:

120920410 120931522(TPM1)

BBUF:

120982367 120985624(TPM1) 120991942(TPM2)

BGAR:

122922586 122927707(TPM1)

MUO:	115456948(TPM3)

GSH:	117349568(TPM3)

DRE:	373076(tpm3)

SRX:

107739596

SANH:

107703245

SGH:	107589334 107599555

CAUA:

113062353

LROH:

127181586(tpm3)

PPRM:

120482574 120483743(tpm3)

MASI:

127425683 127452545 127453900

TROS:

130557555

TDW:

130415287

IPU:	100305075(tpm3) 108280389

IFU:	128616059(tpm3) 128623985

PHYP:

113543071 113543831

SMEO:

124381861(tpm3) 124402887

TFD:	113640268 113641301(tpm3)

TVC:	132842852(tpm3) 132848485

AMEX:

103045363

CMAO:

118797342 118806031(tpm3)

EEE:	113584886 113589122

CHAR:

105896158 105905351 122131999(tpm2)

TRU:	101070032 445911(tpm3)

TFS:	130518392 130532125

TNG:	GSTEN00011539G001

LCO:	104933070 104937304

NCC:	104947129 104947317

TBEN:

117469466 117479238(tpm3)

CGOB:

115015700

PGEO:

117442594 117455089(tpm3)

GACU:

117537053(tpm3) 117557011

EMAC:

134862908 134874692

ELY:	117248496 117265784

EFO:	125893952 125904294

PLEP:

121957687(tpm3) 121965221

SLUC:

116035706 116058491

ECRA:

117957080(tpm3)

ESP:	116679036 116702105

PFLV:

114556715

GAT:	120826655(tpm3)

PPUG:

119197561 119218813(tpm3)

AFB:	129096829(tpm3) 129109133

CLUM:

117738563(tpm3) 117745055

PSWI:

130197075(tpm3) 130213091

MSAM:

119898251 119907194(tpm3)

SCHU:

122863784(tpm3)

CUD:	121513135 121524156

ALAT:

119006052 119017455(tpm3)

MZE:	101475874 101481732

ONL:	100703747 100708478

OAU:	116333393 116334904

OLA:	101168689 101175579(tpm3)

OML:	112137654 112139353 112163052

CSAI:

133440560 133461460

XMA:	102232298 102237830

XCO:	114140176 114156001

XHE:	116717893 116731084

PRET:

103461027 103471928 103477449

PFOR:

103131143 103142797

PLAI:

106940668 106945608

PMEI:

106932553 106932708

GAF:	122830909 122843962(tpm3)

PPRL:

129352798(tpm3) 129355853

CVG:	107095278 107103942

CTUL:

119780939 119784063(tpm3)

GMU:	124865449 124879868(tpm3)

NFU:	107379239 107383233

KMR:

108244469

ALIM:

106511571 106525106 106535523

NWH:	119409210 119429325 119429554 119429557

AOCE:

111569455 111571545 111585116(tpm3)

MCEP:

125020516

CSEM:

103394465

POV:	109642199 109643156 109644353

SSEN:

122775046 122786432(tpm3)

HHIP:

117771132(tpm3) 117776636

HSP:	118113438 118124742(tpm3)

SMAU:

118284561 118310629(tpm3)

LCF:	108884701 108896393(tpm3)

SDU:	111230506 111234083

SLAL:

111649955 111664591

XGL:	120784348 120786838(tpm3)

HCQ:	109512159 109514607

SSCV:

125974880 125979847 125987271

SBIA:

133499943 133513675

PEE:	133395399 133413227

PTAO:

133471296 133487425

BPEC:

110167917

MALB:

109954522 109970852 109974565

BSPL:

114842729

SJO:	128367055 128373959(tpm3)

SASA:

100217347(tpm3) 106570192 106580396 106605468(TPM3)

STRU:

115175775

OTW:	112228813 112229688 112264669

OMY:	110486570 110488220 110496358 110513633

OGO:	123997806 124012645 124043421

ONE:	115103228 115128501 115131505

OKI:	109901959 109903558 109908096

OKE:	118398069 118399439

SALP:

111950280 111954950 111955886 111965034

SNH:

120027183

CCLU:

121570059 121571974 121572414 121585981

ELS:

105019170

PKI:

111838426

LOC:	102685363(tpm3)

PSPA:

121306981 121309832

ARUT:

117962409

PSEX:

120538384 120541630(tpm1)

LCM:

CPLA:

HOC:

LERI:

PMRN:

116946071 116950645 116955038 116957900

LRJ:	133346465 133351652 133353594 133354187

BFO:	118407653 118410327

BBEL:

CIN:

LPIC:

NVE:

ATEN:

ADF:

PDAM:

DGT:

XEN:	124444121 124449452 124450920 124451390

HMG:

100200169

HSY:	130613536 130624198 130645893

» show all

Reference

PMID:11563548

Authors

Perry SV

Title

Vertebrate tropomyosin: distribution, properties and function.

Journal

J Muscle Res Cell Motil 22:5-49 (2001)
DOI:10.1023/A:1010303732441

LinkDB

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