Loxodonta africana (African savanna elephant): 100653766 Help Entry 100653766         CDS       T04351                                  Gene name SHC1 Definition (RefSeq) SHC-transforming protein 1 isoform X2   KO K06279   SHC-transforming protein 1 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav01521   EGFR tyrosine kinase inhibitor resistance lav01522   Endocrine resistance lav04012   ErbB signaling pathway lav04014   Ras signaling pathway lav04062   Chemokine signaling pathway lav04072   Phospholipase D signaling pathway lav04510   Focal adhesion lav04650   Natural killer cell mediated cytotoxicity lav04722   Neurotrophin signaling pathway lav04910   Insulin signaling pathway lav04915   Estrogen signaling pathway lav04917   Prolactin signaling pathway lav04926   Relaxin signaling pathway lav04935   Growth hormone synthesis, secretion and action lav05034   Alcoholism lav05100   Bacterial invasion of epithelial cells lav05206   MicroRNAs in cancer lav05214   Glioma lav05220   Chronic myeloid leukemia lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     100653766 (SHC1)    04014 Ras signaling pathway     100653766 (SHC1)    04072 Phospholipase D signaling pathway     100653766 (SHC1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100653766 (SHC1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     100653766 (SHC1)    04062 Chemokine signaling pathway     100653766 (SHC1)   09152 Endocrine system    04910 Insulin signaling pathway     100653766 (SHC1)    04915 Estrogen signaling pathway     100653766 (SHC1)    04917 Prolactin signaling pathway     100653766 (SHC1)    04926 Relaxin signaling pathway     100653766 (SHC1)    04935 Growth hormone synthesis, secretion and action     100653766 (SHC1)   09156 Nervous system    04722 Neurotrophin signaling pathway     100653766 (SHC1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100653766 (SHC1)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100653766 (SHC1)    05226 Gastric cancer     100653766 (SHC1)    05214 Glioma     100653766 (SHC1)    05220 Chronic myeloid leukemia     100653766 (SHC1)    05224 Breast cancer     100653766 (SHC1)   09165 Substance dependence    05034 Alcoholism     100653766 (SHC1)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     100653766 (SHC1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100653766 (SHC1)    01522 Endocrine resistance     100653766 (SHC1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PID SH2 Delta_lysin Motif Other DBs NCBI-GeneID:  100653766 NCBI-ProteinID:  XP_003415155 UniProt:  G3T4J5 LinkDB All DBs Position Unknown AA seq 583 aa AA seqDB search MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS FFPRMSNLKLANPVGGRPGPRGEPGRAAEDGEGIAGAAMLDSGPLHLLQDMNKLSGGGGR RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNEKVMGPGVSYLVRYMGCVEVLQSMRALD FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL GGVVDMRLREGATPGAARPTPPGGQTPSHLGATLPVGQPVGGEPEVRKQMPPLQPCPGRE LFDDPSYVNVQNLDKVRQAGGGGGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQLMSMA EQLREEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEG VVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL NT seq 1752 nt NT seq  +upstreamnt  +downstreamnt atggatctccttccccccaagcccaagtacaacccacttcggaatgagtctctgtcatcg ctggaggagggggcttcagggtccacgcccccggaggagctgccttccccatcagcctca tccttagggcccatcctgccacctctgcctggggacgacagtcccactaccctgtgctcc ttcttcccccggatgagcaacctgaaactggccaacccagttggggggcgaccagggcca agaggggaaccaggaagggcagccgaggatggggaggggatcgcaggggcagccatgctg gactcaggccccctgcacctcctccaggacatgaacaagctgagtggaggcggcgggcgc aggactcgggtggaagggggccagctggggggcgaggagtggacccgccacgggagcttt gtcaataagcccacgcggggctggctgcatcccaacgagaaagtcatgggacccggggtt tcctacttggttcggtacatgggctgtgtggaggtgctgcagtccatgcgtgccctggac ttcaacacccggactcaggtcaccagggaggccatcagtctggtgtgtgaggctgtgccg ggtgctaagggggcaacaaggaggagaaagccctgtagccgcccactcagctccatcctg gggaggagtaacctgaaatttgctggaatgccaatcactctcacagtctccaccagcagc cttaacctcatggcagctgactgcaaacagatcattgccaaccaccacatgcaatccatc tcgtttgcatccggcggggacccggacacagctgaatatgtcgcctacgttgccaaagac cccgtgaatcagagagcctgccacatcttggagtgtcctgaagggcttgctcaggatgtc atcagcaccattggccaggcctttgagttgcgcttcaaacagtacctcaggaatccaccc aagctagtcactccccacgacaggatggctggctttgatggctcagcttgggatgaggag gaggaagagccacctgaccatcagtactataatgacttcccggggaaggaaccccctctt gggggggtggtggacatgaggcttcgggaaggagccaccccaggggctgctcggcccact ccgcctggtggccagacccccagccacttgggggctaccttgcctgtgggtcagcctgtc gggggggaacctgaagtccgcaaacagatgccacctctgcaaccttgcccaggtagagag ctctttgatgatccctcctatgtcaacgtccagaacttagacaaggtccggcaagcaggg ggcgggggcgggccccccaatcctgccatcaatggcagtgcaccccgggacctctttgac atgaagccctttgaagatgcccttcgggtgcctccacctccccagttgatgtccatggct gagcagctccgagaggagccctggttccacgggaagctgagccggcgggaggctgaggca ctgctgcagctcaacggggacttcctggtgcgggagagcacaaccacacccggccagtat gtgctcaccggcttgcagagtggtcagcccaagcacttgctactggtggaccctgagggt gtggttcggacaaaggatcatcgtttcgagagtgtcagtcatctcatcagctaccacatg gacaatcacttgcccatcatctctgcgggcagcgaactgtgtctacagcagcctgtggag cggaaactgtga

Loxodonta africana (African savanna elephant): 100654827 Help Entry 100654827         CDS       T04351                                  Gene name SHC4 Definition (RefSeq) SHC-transforming protein 4   KO K17449   SHC-transforming protein 4 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav01521   EGFR tyrosine kinase inhibitor resistance lav01522   Endocrine resistance lav04012   ErbB signaling pathway lav04014   Ras signaling pathway lav04062   Chemokine signaling pathway lav04072   Phospholipase D signaling pathway lav04510   Focal adhesion lav04650   Natural killer cell mediated cytotoxicity lav04722   Neurotrophin signaling pathway lav04910   Insulin signaling pathway lav04915   Estrogen signaling pathway lav04917   Prolactin signaling pathway lav04926   Relaxin signaling pathway lav04935   Growth hormone synthesis, secretion and action lav05034   Alcoholism lav05100   Bacterial invasion of epithelial cells lav05206   MicroRNAs in cancer lav05214   Glioma lav05220   Chronic myeloid leukemia lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     100654827 (SHC4)    04014 Ras signaling pathway     100654827 (SHC4)    04072 Phospholipase D signaling pathway     100654827 (SHC4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100654827 (SHC4)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     100654827 (SHC4)    04062 Chemokine signaling pathway     100654827 (SHC4)   09152 Endocrine system    04910 Insulin signaling pathway     100654827 (SHC4)    04915 Estrogen signaling pathway     100654827 (SHC4)    04917 Prolactin signaling pathway     100654827 (SHC4)    04926 Relaxin signaling pathway     100654827 (SHC4)    04935 Growth hormone synthesis, secretion and action     100654827 (SHC4)   09156 Nervous system    04722 Neurotrophin signaling pathway     100654827 (SHC4)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100654827 (SHC4)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100654827 (SHC4)    05226 Gastric cancer     100654827 (SHC4)    05214 Glioma     100654827 (SHC4)    05220 Chronic myeloid leukemia     100654827 (SHC4)    05224 Breast cancer     100654827 (SHC4)   09165 Substance dependence    05034 Alcoholism     100654827 (SHC4)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     100654827 (SHC4)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100654827 (SHC4)    01522 Endocrine resistance     100654827 (SHC4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PID SH2 Delta_lysin Motif Other DBs NCBI-GeneID:  100654827 NCBI-ProteinID:  XP_003420183 UniProt:  G3T2F1 LinkDB All DBs Position Unknown AA seq 630 aa AA seqDB search MRERGQDGLAGLALCVGLFGHAAMLHRAKYSRFRNESVTSLDEGSPGGAVGAKGAPLPPY PALAPHPPAEEATLAPQESPTPLCTLIPRMASVKLASPATLLSLKNFCLGTKEVLRLKLQ DSQEAAPGRPASPETSQNRAGSAPAPQPEPVGHRAHALTPDVCPLPGPGEPVPGIRQDRH FLQHLLGMGMNYYVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANGAIRKRK PPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDT TDYVAYVAKDPVNQRACHILECRSGMAQDVISTIGQAFELRFKQYLKNPSLNTSCESEEV RPDGSAEEREDREYYNEIPGKPPPAGGVSDVRVTVPAAEQMAYCPIRCEKLCYLPGNSKC SSVYENCLEQSRAAGHAHERGVQPQQDTSLLKHTCRVDLFDDPCYINTQAFQSTLGSAWH QSSAQTLGSPWHHGKAPATVQPGATAQSAGTCSLPQIKQQLRNEDCYHGKLSRKAAESLL VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPEGKVRTKDHIFDNVGHLIRYHMDN SLPIISSGSEVSLKQPVRKDSNPGLLDSNK NT seq 1893 nt NT seq  +upstreamnt  +downstreamnt atgcgagagcgcggtcaggacggcctggcaggactcgcgctgtgtgtaggactcttcggg cacgccgcgatgctgcaccgggccaagtacagccgctttcggaacgagtccgtcacgtcc ttggacgaaggcagccccggaggcgcggtcggggccaagggcgctccgctgcccccctac cccgccttggcacctcatccgccggcggaagaagccaccctggcgccccaggagagcccc acgccgctctgcaccttgatcccccgcatggcgagtgtgaagctggccagcccggctacc ttgctgagtctgaagaacttctgcctggggaccaaagaggtgcttcggctaaagctccag gacagccaggaggccgctccgggccgccctgcttcccccgaaaccagtcaaaacagggcc gggtctgcacctgcgccccagcccgagccggtagggcacagagcacacgccttaactccc gacgtctgcccgcttccgggccctggggagccggtccctgggatcaggcaggacagacac tttctccagcacctgttggggatgggcatgaactactatgtgcggtacatgggctgtatt gaagtgctgcaatcaatgaggtcactggattttggaatgagaacccaagttacaagggaa gcaataagtcgcctgtgtgaagctgtccccggagcaaatggagccattagaaagcgaaag cctccagttaaattcctatcaacagttcttggcaaaagtaaccttcagttttcgggaatg aatataaaactgaccatctcaacatgtagcctcacactgatgaatctcgacaaccaacag attattgcaaatcatcatatgcagtctatttcatttgcctctggaggggatcctgatact acagactatgttgcctacgtagctaaagatccagttaatcaacgagcctgtcacatactg gaatgccgcagtggaatggcccaagatgtcatcagtaccatcgggcaggcctttgaactc cggtttaaacagtacttgaaaaatccttctttgaatacttcctgtgaaagtgaggaggtg cgccctgacggcagtgccgaggagagagaagaccgtgagtactacaatgaaatcccaggg aagccgccacctgccggcggtgtttccgatgtgcgggtgacagttccagctgcagagcaa atggcttactgcccaatacggtgtgagaagttgtgctatctgcctggaaactccaagtgc agcagtgtatacgagaactgtttagaacaaagcagggcagcgggtcacgcccatgagaga ggggtacagccccagcaagacacctcgttactgaagcacacgtgtcgagtggacctcttt gatgacccctgctacattaacactcaggcttttcaaagtactcttggctctgcttggcat caaagctcagctcagacgcttgggagcccgtggcaccatggaaaggcaccggcaactgtc cagccaggcgccacagcccagtctgctggcacatgttctttgccacaaattaagcagcag ctgcgaaatgaagactgctaccacggcaagctgagcaggaaggcagcagagagcctcttg gtaaaggatggggactttttggttcgagagagtgcaacatcccctggccaatatgtgctg agtggactgcagggaggccaggcaaaacatcttctcctggtggatcctgaaggcaaggtg aggaccaaagatcatatattcgataatgtcggccaccttatcagataccacatggataac agtttgccaatcatctcttctggaagtgaagtaagccttaaacaaccagtgagaaaagat agtaatccaggacttttggattccaacaaatga

Loxodonta africana (African savanna elephant): 100659669 Help Entry 100659669         CDS       T04351                                  Gene name SHC3 Definition (RefSeq) SHC-transforming protein 3   KO K17448   SHC-transforming protein 3 Organism lav  Loxodonta africana (African savanna elephant) Pathway lav01521   EGFR tyrosine kinase inhibitor resistance lav01522   Endocrine resistance lav04012   ErbB signaling pathway lav04014   Ras signaling pathway lav04062   Chemokine signaling pathway lav04072   Phospholipase D signaling pathway lav04510   Focal adhesion lav04650   Natural killer cell mediated cytotoxicity lav04722   Neurotrophin signaling pathway lav04910   Insulin signaling pathway lav04915   Estrogen signaling pathway lav04917   Prolactin signaling pathway lav04926   Relaxin signaling pathway lav04935   Growth hormone synthesis, secretion and action lav05034   Alcoholism lav05100   Bacterial invasion of epithelial cells lav05214   Glioma lav05220   Chronic myeloid leukemia lav05224   Breast cancer lav05225   Hepatocellular carcinoma lav05226   Gastric cancer Brite KEGG Orthology (KO) [BR:lav00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     100659669 (SHC3)    04014 Ras signaling pathway     100659669 (SHC3)    04072 Phospholipase D signaling pathway     100659669 (SHC3)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100659669 (SHC3)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     100659669 (SHC3)    04062 Chemokine signaling pathway     100659669 (SHC3)   09152 Endocrine system    04910 Insulin signaling pathway     100659669 (SHC3)    04915 Estrogen signaling pathway     100659669 (SHC3)    04917 Prolactin signaling pathway     100659669 (SHC3)    04926 Relaxin signaling pathway     100659669 (SHC3)    04935 Growth hormone synthesis, secretion and action     100659669 (SHC3)   09156 Nervous system    04722 Neurotrophin signaling pathway     100659669 (SHC3)  09160 Human Diseases   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100659669 (SHC3)    05226 Gastric cancer     100659669 (SHC3)    05214 Glioma     100659669 (SHC3)    05220 Chronic myeloid leukemia     100659669 (SHC3)    05224 Breast cancer     100659669 (SHC3)   09165 Substance dependence    05034 Alcoholism     100659669 (SHC3)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     100659669 (SHC3)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100659669 (SHC3)    01522 Endocrine resistance     100659669 (SHC3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PID SH2 Motif Other DBs NCBI-GeneID:  100659669 NCBI-ProteinID:  XP_003421619 LinkDB All DBs Position Unknown AA seq 618 aa AA seqDB search MLQRTKYNRFRNDSVTSVDELIHNLSMSGGSSGGGKVSAVPATSAASPYLVSSEALRKAP DDGPSSLGHLLHKVSHLKLSTSGLRSLSSAARERAGAKLTGSCSAPSLAAGAPDRTCARA PAPGSARPAPREMSAARKGRPGEELLPRHPRGWLHASDQVLGPGVTYVVKYLGCIEVLRS MRSLDFSTRTQITREAISRVCEAVPGARGAIKKRKPPSKMLSSILGKSNLQFAGMSISLT ISTTSLNLRTPDSKQIIANHHMQSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCGG LAQDVISSIGQAFELRFKQYLQCPSKMPALQDRMQSLDEPWTKEEGDDSDHPYYNSMPNK VPPPGGFHDARQKVRPYVPDTAQFAGKEQTYYQGRHLGDKFGEDWQQPSVRQGSLDIYSM PERKSLEAPPGVAPTYVNTQNIPQQAGLTQAGAALNMDTGAASSSGENSPRKDLFDMKPF EDALKNQTMGPMLSKAASVECISPIPPRAPDAKMVEELKEEPWYQGEMSRKEAEGLLKKD GDFLVRRSTTNSGSFVLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSIGHLINHHLENGIP IVSAGSDLCLQQPVERKH NT seq 1857 nt NT seq  +upstreamnt  +downstreamnt atgctgcaacggaccaagtataatcgcttcaggaatgattcggtgacatcagtcgatgaa cttatccacaacctgtccatgagcggcggcagcagcggcggcggcaaggtctcagcggtg cccgcgacctccgcggcgtccccctacctggtctccagtgaggcgctgcgcaaagcgccg gacgatgggcccagcagcctgggccacctgctccacaaggtgtcccacctgaaactctcc acctcgggcctccgtagcctgtcgtccgccgcgagggagcgggccggcgccaagctcacc ggcagctgcagcgctcccagcctggccgccggcgccccggaccgcacatgtgcccgcgcc ccggccccaggcagtgcgcggccggccccgagagagatgagcgccgccaggaagggccgg cccggcgaggagctgctgcccaggcacccccggggctggctgcacgccagcgaccaggtc ttggggcccggagtgacgtacgtcgtcaagtacttggggtgcattgaagttctgcgctca atgaggtctcttgacttcagtacaagaacacaaattaccagggaagccatcagccgtgtt tgtgaagctgttcctggtgccagaggagccatcaagaaaaggaagcctccaagcaaaatg ctgtccagcatcttgggaaagagcaacctccagtttgcaggaatgagtatctctctcacc atttccaccaccagcctgaatctgcggacacctgactccaaacagatcattgcaaaccat cacatgcagtccatctcctttgcctccggaggagacccggacacaacagactatgttgcc tatgtagctaaagaccctgttaatcgcagagcttgtcacatactggaatgttgtggaggg ctggcccaggatgtcatcagctccattggacaagccttcgagcttcggtttaagcaatat ttacagtgtccttccaagatgcctgctcttcaagatcggatgcagagtctggatgagcca tggaccaaagaagagggagatgattctgaccatccatactacaatagcatgccaaacaag gtgcctcctccaggggggtttcatgatgctcgacagaaagttaggccctatgttcctgac acagcccagttcgcaggaaaagagcaaacttattaccagggaagacacttaggagacaag ttcggtgaagactggcaacaaccatctgttagacaagggtctttggacatctacagcatg ccagaaagaaagtcacttgaggcccctccaggagtagcacccacctacgtcaatacccag aacatcccacagcaggctgggctgacccaggcaggagctgcactgaacatggacacggga gccgccagcagcagtggagaaaacagcccgcggaaagatttgtttgacatgaagcctttt gaagatgctctcaagaaccagaccatgggacccatgttaagcaaggctgcctccgtagag tgcatcagccccatcccgcccagagccccagatgccaagatggtggaagaactaaaggaa gagccatggtaccaaggagagatgagcaggaaggaggcggaggggctgctcaagaaggat ggggacttcctggtcagaagaagtaccacaaactccggttccttcgtcctcacgggcatg cacaacggccaggccaagcacctgctgctggtggatcctgaaggcacgatccgcaccaag gacagggtctttgacagcatcggccatctcatcaaccaccacctggagaacggcataccc atcgtctctgccgggagtgacctctgcctccagcagccagtggaaagaaagcactga

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