Entry |
|
Name |
EBV LMP2A/2B to IFN signaling pathway
|
Definition |
(LMP2A,LMP2B) -| (IFNAR1+IFNAR2) |
Expanded |
(K19460,K23074) -| (3454+3455) |
Class |
|
Type |
Pathogen
|
Pathway |
|
Disease |
|
Gene |
3454 | IFNAR1; interferon alpha and beta receptor subunit 1 |
3455 | IFNAR2; interferon alpha and beta receptor subunit 2 |
|
Perturbant |
K19460 (LMP2A) | LMP2A; EBV latent membrane protein 2A |
K23074 (LMP2B) | LMP2B; EBV latent membrane protein 2B |
|
Reference |
|
Authors |
Ning S |
Title |
Innate immune modulation in EBV infection. |
Journal |
|
Reference |
|
Authors |
Wang Y, Banerjee S, Ding L, Cai C, Wei F, Cai Q |
Title |
The regulatory role of protein phosphorylation in human gammaherpesvirus associated cancers. |
Journal |
|
Reference |
|
Authors |
Shah KM, Stewart SE, Wei W, Woodman CB, O'Neil JD, Dawson CW, Young LS |
Title |
The EBV-encoded latent membrane proteins, LMP2A and LMP2B, limit the actions of interferon by targeting interferon receptors for degradation. |
Journal |
|
Reference |
|
Authors |
Melchjorsen J |
Title |
Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines. |
Journal |
|
LinkDB |
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