KEGG   Pan troglodytes (chimpanzee): 455214
Entry
455214            CDS       T01005                                 

Gene name
TP53
Definition
(RefSeq) cellular tumor antigen p53 isoform X2
  KO
K04451  tumor protein p53
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr01522  Endocrine resistance
ptr01524  Platinum drug resistance
ptr04010  MAPK signaling pathway
ptr04071  Sphingolipid signaling pathway
ptr04110  Cell cycle
ptr04115  p53 signaling pathway
ptr04137  Mitophagy - animal
ptr04151  PI3K-Akt signaling pathway
ptr04210  Apoptosis
ptr04211  Longevity regulating pathway
ptr04216  Ferroptosis
ptr04218  Cellular senescence
ptr04310  Wnt signaling pathway
ptr04722  Neurotrophin signaling pathway
ptr04919  Thyroid hormone signaling pathway
ptr05012  Parkinson disease
ptr05014  Amyotrophic lateral sclerosis
ptr05016  Huntington disease
ptr05160  Hepatitis C
ptr05161  Hepatitis B
ptr05162  Measles
ptr05163  Human cytomegalovirus infection
ptr05165  Human papillomavirus infection
ptr05166  Human T-cell leukemia virus 1 infection
ptr05167  Kaposi sarcoma-associated herpesvirus infection
ptr05168  Herpes simplex virus 1 infection
ptr05169  Epstein-Barr virus infection
ptr05200  Pathways in cancer
ptr05202  Transcriptional misregulation in cancer
ptr05203  Viral carcinogenesis
ptr05205  Proteoglycans in cancer
ptr05206  MicroRNAs in cancer
ptr05210  Colorectal cancer
ptr05212  Pancreatic cancer
ptr05213  Endometrial cancer
ptr05214  Glioma
ptr05215  Prostate cancer
ptr05216  Thyroid cancer
ptr05217  Basal cell carcinoma
ptr05218  Melanoma
ptr05219  Bladder cancer
ptr05220  Chronic myeloid leukemia
ptr05222  Small cell lung cancer
ptr05223  Non-small cell lung cancer
ptr05224  Breast cancer
ptr05225  Hepatocellular carcinoma
ptr05226  Gastric cancer
ptr05230  Central carbon metabolism in cancer
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    455214 (TP53)
   04310 Wnt signaling pathway
    455214 (TP53)
   04071 Sphingolipid signaling pathway
    455214 (TP53)
   04151 PI3K-Akt signaling pathway
    455214 (TP53)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    455214 (TP53)
  09143 Cell growth and death
   04110 Cell cycle
    455214 (TP53)
   04210 Apoptosis
    455214 (TP53)
   04216 Ferroptosis
    455214 (TP53)
   04115 p53 signaling pathway
    455214 (TP53)
   04218 Cellular senescence
    455214 (TP53)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    455214 (TP53)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    455214 (TP53)
  09149 Aging
   04211 Longevity regulating pathway
    455214 (TP53)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    455214 (TP53)
   05202 Transcriptional misregulation in cancer
    455214 (TP53)
   05206 MicroRNAs in cancer
    455214 (TP53)
   05205 Proteoglycans in cancer
    455214 (TP53)
   05203 Viral carcinogenesis
    455214 (TP53)
   05230 Central carbon metabolism in cancer
    455214 (TP53)
  09162 Cancer: specific types
   05210 Colorectal cancer
    455214 (TP53)
   05212 Pancreatic cancer
    455214 (TP53)
   05225 Hepatocellular carcinoma
    455214 (TP53)
   05226 Gastric cancer
    455214 (TP53)
   05214 Glioma
    455214 (TP53)
   05216 Thyroid cancer
    455214 (TP53)
   05220 Chronic myeloid leukemia
    455214 (TP53)
   05217 Basal cell carcinoma
    455214 (TP53)
   05218 Melanoma
    455214 (TP53)
   05219 Bladder cancer
    455214 (TP53)
   05215 Prostate cancer
    455214 (TP53)
   05213 Endometrial cancer
    455214 (TP53)
   05224 Breast cancer
    455214 (TP53)
   05222 Small cell lung cancer
    455214 (TP53)
   05223 Non-small cell lung cancer
    455214 (TP53)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    455214 (TP53)
   05014 Amyotrophic lateral sclerosis
    455214 (TP53)
   05016 Huntington disease
    455214 (TP53)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    455214 (TP53)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    455214 (TP53)
   05161 Hepatitis B
    455214 (TP53)
   05160 Hepatitis C
    455214 (TP53)
   05162 Measles
    455214 (TP53)
   05168 Herpes simplex virus 1 infection
    455214 (TP53)
   05163 Human cytomegalovirus infection
    455214 (TP53)
   05167 Kaposi sarcoma-associated herpesvirus infection
    455214 (TP53)
   05169 Epstein-Barr virus infection
    455214 (TP53)
   05165 Human papillomavirus infection
    455214 (TP53)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    455214 (TP53)
   01522 Endocrine resistance
    455214 (TP53)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ptr03000]
    455214 (TP53)
   03036 Chromosome and associated proteins [BR:ptr03036]
    455214 (TP53)
   03400 DNA repair and recombination proteins [BR:ptr03400]
    455214 (TP53)
Transcription factors [BR:ptr03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   p53
    455214 (TP53)
Chromosome and associated proteins [BR:ptr03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     455214 (TP53)
DNA repair and recombination proteins [BR:ptr03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    455214 (TP53)
SSDB
Motif
Pfam: P53 P53_tetramer TAD2 P53_TAD
Other DBs
NCBI-GeneID: 455214
NCBI-ProteinID: XP_001172077
Ensembl: ENSPTRG00000008703
VGNC: 9734
UniProt: H2QC53 A0A6D2Y7Y2
LinkDB
Position
17
AA seq 393 aa
MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGP
DEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAK
SVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE
RCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNS
SCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELP
PGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPG
GSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD
NT seq 1182 nt   +upstreamnt  +downstreamnt
atggaggagccgcagtcagatcctagcgtcgagccccctctgagtcaggaaacattttca
gacctatggaaactacttcctgaaaacaacgttctgtcccccttgccatcccaagcaatg
gatgatttgatgctgtccccggacgatattgaacaatggttcactgaagacccaggtcca
gatgaagctcccagaatgccagaggctgctccccccgtggcccctgcaccagcagctcct
acaccggcggcccctgcaccagccccctcctggcccctgtcatcttctgtcccttcccag
aaaacctaccagggcagctacggtttccgtctgggcttcttgcattctgggacagccaag
tctgtgacttgcacgtactcccctgccctcaacaagatgttttgccaactggccaagacc
tgccctgtgcagctgtgggttgattccacacccccacctggcacccgcgtccgcgccatg
gccatctacaagcagtcacagcacatgacggaggttgtgaggcgctgcccccaccatgag
cgctgctcagatagcgatggtctggcccctcctcagcatcttatccgagtggaaggaaat
ttgcgtgtggagtatttggatgacagaaacacttttcgacatagtgtggtggtgccctat
gagccgcctgaggttggctctgactgtaccaccatccactacaactacatgtgtaacagt
tcctgcatgggcggcatgaaccggaggcccatcctcaccatcatcacactggaagactcc
agtggtaatctactgggacggaacagctttgaggtgcgtgtttgtgcctgtcctgggaga
gaccggcgcacagaggaagagaatctccgcaagaaaggggagcctcaccacgagctgccc
ccagggagcactaagcgagcactgcccaacaacaccagctcctctccccagccaaagaag
aaaccactggatggagaatatttcacccttcagatccgtgggcgtgagcgcttcgagatg
ttccgagagctgaatgaggccttggaactcaaggatgcccaggctgggaaggagccaggg
gggagcagggctcactccagccacctgaagtccaaaaagggtcagtctacctcccgccat
aaaaaactcatgttcaagacagaagggcctgactcagactga

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