Pan troglodytes (chimpanzee): 466915
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Entry
466915 CDS
T01005
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04010
MAPK signaling pathway
ptr04020
Calcium signaling pathway
ptr04022
cGMP-PKG signaling pathway
ptr04024
cAMP signaling pathway
ptr04260
Cardiac muscle contraction
ptr04261
Adrenergic signaling in cardiomyocytes
ptr04270
Vascular smooth muscle contraction
ptr04713
Circadian entrainment
ptr04720
Long-term potentiation
ptr04723
Retrograde endocannabinoid signaling
ptr04724
Glutamatergic synapse
ptr04725
Cholinergic synapse
ptr04726
Serotonergic synapse
ptr04727
GABAergic synapse
ptr04728
Dopaminergic synapse
ptr04742
Taste transduction
ptr04911
Insulin secretion
ptr04912
GnRH signaling pathway
ptr04921
Oxytocin signaling pathway
ptr04924
Renin secretion
ptr04925
Aldosterone synthesis and secretion
ptr04927
Cortisol synthesis and secretion
ptr04929
GnRH secretion
ptr04930
Type II diabetes mellitus
ptr04934
Cushing syndrome
ptr04935
Growth hormone synthesis, secretion and action
ptr05010
Alzheimer disease
ptr05020
Prion disease
ptr05022
Pathways of neurodegeneration - multiple diseases
ptr05031
Amphetamine addiction
ptr05207
Chemical carcinogenesis - receptor activation
ptr05410
Hypertrophic cardiomyopathy
ptr05412
Arrhythmogenic right ventricular cardiomyopathy
ptr05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
466915 (CACNA1C)
04020 Calcium signaling pathway
466915 (CACNA1C)
04024 cAMP signaling pathway
466915 (CACNA1C)
04022 cGMP-PKG signaling pathway
466915 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
466915 (CACNA1C)
04929 GnRH secretion
466915 (CACNA1C)
04912 GnRH signaling pathway
466915 (CACNA1C)
04921 Oxytocin signaling pathway
466915 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
466915 (CACNA1C)
04924 Renin secretion
466915 (CACNA1C)
04925 Aldosterone synthesis and secretion
466915 (CACNA1C)
04927 Cortisol synthesis and secretion
466915 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
466915 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
466915 (CACNA1C)
04270 Vascular smooth muscle contraction
466915 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
466915 (CACNA1C)
04727 GABAergic synapse
466915 (CACNA1C)
04725 Cholinergic synapse
466915 (CACNA1C)
04728 Dopaminergic synapse
466915 (CACNA1C)
04726 Serotonergic synapse
466915 (CACNA1C)
04720 Long-term potentiation
466915 (CACNA1C)
04723 Retrograde endocannabinoid signaling
466915 (CACNA1C)
09157 Sensory system
04742 Taste transduction
466915 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
466915 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
466915 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
466915 (CACNA1C)
05020 Prion disease
466915 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
466915 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
466915 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
466915 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
466915 (CACNA1C)
05414 Dilated cardiomyopathy
466915 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
466915 (CACNA1C)
04934 Cushing syndrome
466915 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
ptr04040
]
466915 (CACNA1C)
Ion channels [BR:
ptr04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
466915 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
GPHH
CAC1F_C
Ca_chan_IQ
PKD_channel
Motif
Other DBs
NCBI-GeneID:
466915
NCBI-ProteinID:
XP_016778223
Ensembl:
ENSPTRG00000004526
VGNC:
51248
LinkDB
All DBs
Position
10:9135636..9859443
Genome browser
AA seq
2251 aa
AA seq
DB search
MPLTPNLDSSLGPLQSRMTRGWPDRAGVLPSSWSPAAAPGCRRRMQMLSSGELGHLTGSN
YGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSST
QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV
ALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLD
FIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLN
SIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALE
TGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRD
WPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLD
WITQAEDIDPENEDEGMDEEKPRNRGTPAGMLDQKKGKFAWFSHSTETHVSMPTSETESV
NTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLV
FLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCF
VVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASL
LLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYD
GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE
RKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDK
SPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCH
RIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTA
YGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYI
TYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGP
IYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL
NMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTF
DALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGI
RTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAV
LLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFL
IINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQP
PLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQG
AEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEY
FRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAV
SAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEK
LVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEV
AWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDAEACSEPSLLSTEMLSYQDDENR
QLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHH
QALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQLVPTLRLEGVESSEKLNSSF
PSIHCGSWAETTPGGGGSSAARRARPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLG
QFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDR
AGGEEDAGCVRARGRLSEEELQDSRVYVSSL
NT seq
6756 nt
NT seq
+upstream
nt +downstream
nt
atgccactgactcctaacttggactcctcacttggacccttgcagagcagaatgacacga
ggctggccagaccgtgctggggtcctgccctcatcctggtccccagcagcagcacctggg
tgcaggaggaggatgcagatgctgtcttcaggggagctgggccatttgacaggttccaac
tatgggagcccacgccccgcccatgccaacatgaatgccaatgcggcagcggggctggcc
cctgagcacatccccaccccgggggccgccctgtcctggcaggcggccatcgacgcagcc
cggcaggctaagctgatgggcagcgctggcaatgcgaccatctccacagtcagctccacg
cagcggaagcggcagcaatatgggaaacccaagaagcagggcagcaccacggccacacgc
ccgccccgagccctgctctgcctgaccctgaagaaccccatccggagggcctgcatcagc
attgtcgaatggaaaccatttgaaataattattttactgactatttttgccaattgtgtg
gccttagcgatctatattccctttccagaagatgattccaacgccaccaattccaacctg
gaacgagtggaatatctctttctcataatttttacggtggaagcgtttttaaaagtaatc
gcctatggactcctctttcaccccaatgcctacctccgcaacggctggaacctactagat
tttataattgtggttgtggggctttttagtgcaattttagaacaagcaaccaaagcagat
ggggcaaacgctctcggagggaaaggggccggatttgatgtgaaggcgctgagggccttc
cgcgtgctgcgccccctgcggctggtgtccggagtcccaagtctccaggtggtcctgaat
tccatcatcaaggccatggtccccctgctgcacattgccctgcttgtgctgtttgtcatc
atcatctacgccatcatcggcttggagctcttcatggggaagatgcacaagacctgctac
aaccaggagggcatagcagatgttccagcagaagatgacccttccccttgtgcgctggaa
acgggccatgggcggcagtgccagaacggcacggtgtgcaagcccggctgggatggtccc
aagcacggcatcaccaactttgacaactttgccttcgccatgctcacggtgttccagtgc
atcaccatggagggctggacggacgtgctgtactgggtcaatgatgccgtaggaagggac
tggccctggatctattttgttacactaatcatcatagggtcattttttgtacttaacttg
gttctcggtgtgcttagcggagagttttccaaagagagggagaaggccaaggcccgggga
gatttccagaagctgcgggagaagcagcagctagaagaggatctcaaaggctacctggat
tggatcactcaggccgaagacatcgatcccgagaatgaggacgaaggcatggatgaggag
aagccccgaaacagaggcactccggcgggcatgcttgatcagaagaaagggaagtttgct
tggtttagtcactccacagaaacccatgtgagcatgcccaccagtgagaccgagtccgtc
aacaccgaaaacgtggctggaggtgacatcgagggagaaaactgcggggccaggctggcc
caccggatctccaagtcaaagttcagccgctactggcgccggtggaatcggttctgcaga
aggaagtgccgcgccgcagtcaagtctaatgtcttctactggctggtgattttcctggtg
ttcctcaacacgctcaccattgcctctgagcactacaaccagccccactggctcacagaa
gtccaagacacggcgaacaaggccctgctggccctgttcacggcggagatgctcctgaag
atgtacagcctgggcctgcaggcctacttcgtgtccctcttcaaccgctttgactgcttc
gtcgtgtgtggcggcatcctggagaccatcctggtggagaccaagatcatgtccccactg
ggcatctccgtgctcagatgcgtccggctgctgaggattttcaagatcacgaggtactgg
aactccttgagcaacctggtggcatccttgctgaactctgtgcgctccatcgcctccctg
ctccttctcctcttcctcttcatcatcatcttctccctcctggggatgcagctctttgga
ggaaagttcaactttgatgagatgcagacccggaggagcacattcgataacttcccccag
tccctcctcactgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgat
gggatcatggcttatggcggcccctcttttccagggatgttagtctgtatttacttcatc
atcctcttcatctgtggaaactatatcctactgaatgtgttcttggccattgctgtggac
aacctggctgatgctgagagcctcacatctgcccaaaaggaggaggaagaggagaaggag
agaaagaagctggccaggactgccagcccagagaagaaacaagagttggtggagaagcca
gcagtgggggaatccaaggaggagaagattgagctgaaatccatcacggctgacggagag
tctccacccgccaccaagatcaacatggatgacctccagcccaatgaaaatgaggataag
agcccctaccccaacccagaaactacaggagaagaggatgaggaggagccagagatgcct
gtcggccctcgcccacgaccactctctgagcttcaccttaaggaaaaggcagtgcccatg
ccagaagccagcgcgtttttcatcttcagctctaacaacaggtttcgcctccagtgccac
cgcattgtcaatgacacgatcttcaccaacctgatcctcttcttcattctgctcagcagc
atttccctggctgctgaggacccggtccagcacacctccttcaggaaccatattctgttt
tattttgatattgtttttaccaccattttcaccattgaaattgctctgaagatgactgct
tatggggctttcctgcacaagggctctttctgccggaactacttcaacatcctggacctg
ctggtggtcagcgtgtccctcatctcctttggcatccagtccagtgcaatcaatgtcgtg
aagatcttgcgagtcctgcgagtactcaggcccctgagggccatcaacagggccaagggg
ctaaagcatgtggttcagtgtgtgtttgtcgccatccggaccatcgggaacatcgtgatt
gtcaccaccctgctgcagttcatgtttgcctgcatcggggtccagctcttcaagggaaag
ctgtacacctgttcagacagttccaagcagacagaggcggaatgcaagggcaactacatc
acatacaaagacggggaggttgaccaccccatcatccaaccccgcagctgggagaacagc
aagtttgactttgacaatgttctggcagccatgatggccctcttcaccgtctccaccttc
gaagggtggccagagctgctgtaccgctccatcgactcccacacggaagacaagggcccc
atctacaactaccgtgtggagatctccatcttcttcatcatctacatcatcatcatcgcc
ttcttcatgatgaacatcttcgtgggcttcgtcatcgtcacctttcaggagcagggggag
caggagtacaagaactgtgagctggacaagaaccagcgacagtgcgtggaatacgccctc
aaggcccggcccctgcggaggtacatccccaagaaccagcaccagtacaaagtgtggtac
gttgtcaactccacctacttcgagtacctgatgttcgtcctcatcctgctcaacaccatc
tgcctggccatgcagcactacggccagagctgcctgttcaaaatcgccatgaacatcctc
aacatgctcttcactggcctcttcaccgtggagatgatcctgaagctcattgccttcaaa
cccaagggttactttagtgatccctggaatgtttttgacttcctcatcgtaattggcagc
ataattgacgtcattctcagtgagactaatcactatttctgtgatgcatggaatacattt
gacgccttgattgttgtgggtagcattgttgatatagcaatcaccgaggtaaacccagct
gaacatacccaatgctctccctctatgaacgcagaggaaaactcccgcatctccatcacc
ttcttccgcctgttccgggtcatgcgtctggtgaagctgctgagccgtggggagggcatc
cggacgctgctgtggaccttcatcaagtccttccaggccctgccctatgtggccctcctg
atcgtgatgctgttcttcatctacgcggtgatcgggatgcaggtgtttgggaaaattgcc
ctgaatgataccacagagatcaaccggaacaacaactttcagaccttcccccaggctgtg
ctgctcctcttcaggtgtgccaccggggaggcctggcaggacatcatgctggcctgcatg
ccaggcaagaagtgtgccccggagtcagagcccagcaacagcacggagggtgaaacaccc
tgtggtagcagctttgctgtcttctacttcatcagcttctacatgctctgtgccttcctg
atcatcaacctctttgtagctgtcatcatggacaactttgactacctgacaagggactgg
tccatccttggtccccaccacctggatgagtttaaaagaatctgggcagagtatgaccct
gaagccaagggtcgtatcaaacacctggatgtggtgaccctcctccggcggattcagccg
ccactaggtttcgggaagctgtgccctcaccgcgtggcttgcaaacgcctggtctccatg
aacatgcctctgaacagcgacgggacagtcatgttcaatgccactctgtttgccctggtc
aggacggccctgaggatcaaaacagaagagggacccagcccatcagaggcccaccaaggg
gctgaggatcctttccgccctgcagggaacctagaacaagccaatgaggagctgcgggcg
atcatcaagaagatctggaagcggaccagcatgaagctgctggaccaggtggtgccccct
gcaggtgatgatgaggtcaccgttggcaagttctacgccacgttcctgatccaggagtac
ttccggaagttcaagaagcgcaaagagcagggccttgtgggcaagccctcccagaggaac
gcactgtctctgcaggctggcttgcgcacactgcatgacatcgggcctgagatccgacgg
gccatctctggagatctcaccgctgaggaggagctggacaaggccatgaaggaggctgtg
tccgctgcttctgaagatgacatcttcaggagggccggtggcctgttcggcaaccacgtc
agctactaccaaagcgacggccggagcgccttcccccagaccttcaccactcagcgcccg
ctgcacatcaacaaggcgggcagcagccagggcgacactgagtcgccatcccacgagaag
ctggtggactccaccttcaccccgagcagctactcgtccaccggctccaacgccaacatc
aacaacgccaacaacaccgccctgggtcgcctccctcgccccgccggctaccccagcacg
gtcagcactgtggagggccacgggccccccttgtcccctgccatccgggtgcaggaggtg
gcgtggaagctcagctccaacaggtgccactcccgggagagccaggcagccatggcgggt
caggaggagacgtctcaggatgagacctatgaagtgaagatgaaccatgacgcggaggcc
tgcagtgagcccagcctgctctccacagagatgctctcctaccaggatgacgaaaatcgg
caactgacgctcccagaggaggacaagagggacatccggcaatctccaaagaggggtttc
ctccgctctgcctcactaggtcgaagggcctccttccacctggaatgtctgaagcgacag
aaggaccgagggggagacatctctcagaagacagtcctgcccttgcatctggttcatcat
caggcattggcagtggcaggcctgagccccctcctccagagaagccattcccctgcctca
ttccctaggccttttgccaccccaccagccacacctggtagccgaggctggcccccacag
ctcgtccccaccctgcggctggagggggtcgagtccagtgagaaactcaacagcagcttc
ccatccatccactgcggatcctgggctgagaccacccccggtggcgggggcagcagcgcc
gcccggagagcccggcccgtctccctcatggtgcccagccaggctggggccccagggagg
cagttccacggcagtgccagcagcctggtggaagcggtcttgatttcagaaggactgggg
cagtttgctcaagatcccaagttcatcgaggtcaccacccaggagctggccgacgcctgc
gacatgaccatagaggagatggagagcgcggccgacaacatcctcagcgggggcgcccca
cagagccccaatggcgccctcttaccctttgtgaactgcagggacgcggggcaggaccga
gccgggggcgaagaggacgcgggctgtgtgcgcgcgcggggtcgactgagtgaggaggag
ctccaggacagcagggtctacgtcagcagcctgtag
DBGET
integrated database retrieval system
