KEGG   ENZYME: 1.5.1.11
Entry
EC 1.5.1.11                 Enzyme                                 
Name
D-octopine dehydrogenase;
D-octopine synthase;
octopine dehydrogenase;
octopine:NAD+ oxidoreductase;
ODH;
2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)
Reaction(IUBMB)
N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH + H+ [RN:R00562]
Reaction(KEGG)
R00562
Substrate
N2-(D-1-carboxyethyl)-L-arginine [CPD:C04137];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
L-arginine [CPD:C00062];
pyruvate [CPD:C00022];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
In the reverse direction, acts also on L-ornithine, L-lysine and L-histidine.
History
EC 1.5.1.11 created 1972
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K23233  D-octopine dehydrogenase
Genes
GAE121375148 121375171 121375569 121375879
HRF124130929 124130932 124135646 124141222 124141236 124143581
HRJ124269418 124275434 124275436 124275497 124279633 124285795 124285908
CRG105331524 105331525 105331526 105331584 105342796
MYI110451252
PMAX117318100 117324891 117325339 117332653
MMER123524662 123525369 123525370 123525934
OSN115219799 115219972
Reference
1
  Authors
Kemp, J.D., Hack, E., Sutton, D.W. and El-Wakil, M.
  Title
Unusual amino acids and their relationship to tumorigenesis.
  Journal
Proc Int Conf Plant Pathol Bact 4th:183-188 (1979)
Reference
2  [PMID:4310628]
  Authors
van Thoai N, Huc C, Pho DB, Olomucki A.
  Title
[Octopine dehydrogenase. Purification and catalytic properties]
  Journal
Biochim Biophys Acta 191:46-57 (1969)
DOI:10.1016/0005-2744(69)90313-1
Other DBs
ExplorEnz - The Enzyme Database: 1.5.1.11
IUBMB Enzyme Nomenclature: 1.5.1.11
ExPASy - ENZYME nomenclature database: 1.5.1.11
BRENDA, the Enzyme Database: 1.5.1.11
CAS: 37256-27-2
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