KEGG   ENZYME: 1.5.1.24
Entry
EC 1.5.1.24                 Enzyme                                 
Name
N5-(carboxyethyl)ornithine synthase;
5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)
Reaction(IUBMB)
N5-(L-1-carboxyethyl)-L-ornithine + NADP+ + H2O = L-ornithine + pyruvate + NADPH + H+ [RN:R00666]
Reaction(KEGG)
R00666
Substrate
N5-(L-1-carboxyethyl)-L-ornithine [CPD:C04210];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
L-ornithine [CPD:C00077];
pyruvate [CPD:C00022];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
In the reverse direction, L-lysine can act instead of L-ornithine, but more slowly. Acts on the amino group. cf. EC 1.5.1.16, D-lysopine dehydrogenase.
History
EC 1.5.1.24 created 1990
Orthology
K00298  N5-(carboxyethyl)ornithine synthase
Genes
PPRPBPRB1416
PALNB0W48_20115
SALMD0Y50_08140
MEINmethR_P1275
FHIFSC454_06490
FPHFphi_1609
FPTBZ13_383
FPIBF30_1884
FPMLA56_557
FPXKU46_1691
FPJLA02_1634
FNAOOM_1398
FNLM973_04710
FHACDV26_04925
FRXF7310_01560
FADCDH04_01265
MMWMmwyl1_3833
HYLLPB072_17710
HYCE5678_09885
MPLIE1742_23480
ANTArnit_1194
AMARAMRN_1223(ceo)
ACAAACAN_1276(ceo)
HYTHXX25_04305
HBAHbal_1161
VIGBKP57_14870
LWIUE46_00935
BTHSCNY62_04875
PLNPlano_2285
PKUAUO94_04310
PRTAUC31_15320
PLLI858_011460
PANABBH88_07530
PDGBCM40_03835
PHCBBI08_08675
PPLABBI15_07260
PFAEAJGP001_13235
PLXCW734_13335
PMATBBI11_12805
PDECH1Q58_12105
SPOSDV702_04335
PANCE2636_12735
LLAL64332(ceo)
LLKLLKF_0282(ceo) LLKF_2279(ceo)
LLTCVCAS_1204(ceo)
LLSlilo_0584(ceo) lilo_1175(ceo)
LLDP620_07035
LLXNCDO2118_0284(ceo)
LLJLG36_1164(ceo)
LLMllmg_1237(ceo)
LLNLLNZ_06370 LLNZ_06540
LLWkw2_1126
LGRLCGT_1205
LGVLCGL_1225
LPKLACPI_1770
LRNCMV25_08150
LTIJW886_04715
LCARBHS00_01650
LPAABHS01_07915
LMALLM596_05535
EGVEGCR1_18955
VPIBW732_08670
VCPH9L18_15050
CRNCAR_c22550(ceo)
CMLBN424_537
CAWQ783_10275
CARCNY10_2074
CVDLHA31_08250
MARRBKP56_03415
JEHEJN90_04190
CTCCTC_00375
CTETBN906_00397
CBOCBO0515(ceo)
CBACLB_0555(ceo)
CBHCLC_0588(ceo)
CBYCLM_0606(ceo)
CBLCLK_3726(ceo)
CBBCLD_0234(ceo)
CBICLJ_B0591(ceo)
CBFCLI_0595(ceo)
CBMCBF_0563(ceo)
CBJH04402_00539
CLDCLSPO_c05530(ceo)
CCOHSAMEA4530647_0242(ceo)
CCAAKQH81_13680
CAPREQM14_11520
SINTK5I26_03770 K5I26_13125
ERDG7062_04315
ABSIA9CBEGH2_21820(ald)
LCGL3BBH23_17870(ald)
VBCC5Q97_18545
DRCG0Q07_07665
SDJNCTC13534_05009(ald2_1)
CAMUCA2015_2068
ALSDJ013_10265
FLLEI427_11725
FKAKM029_17770
MARFCJ739_2261
AQDD1816_11485
SABUMBM09_03920
FBEFF125_14430
WVIWeevi_0958
 » show all
Reference
1  [PMID:2498334]
  Authors
Thompson J
  Title
N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase from Streptococcus lactis. Purification and partial characterization.
  Journal
J Biol Chem 264:9592-601 (1989)
Other DBs
ExplorEnz - The Enzyme Database: 1.5.1.24
IUBMB Enzyme Nomenclature: 1.5.1.24
ExPASy - ENZYME nomenclature database: 1.5.1.24
BRENDA, the Enzyme Database: 1.5.1.24
CAS: 129070-70-8
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